-
2
-
-
0029099086
-
Efficacy of metformin in patients with non-insulin-dependent diabetes mellitus
-
The Multicenter Metformin Study Group
-
DeFronzo, R.A.; Goodman, A.M. Efficacy of metformin in patients with non-insulin-dependent diabetes mellitus. The Multicenter Metformin Study Group. N. Engl. J. Med. 1995, 333, 541-549.
-
(1995)
N. Engl. J. Med
, vol.333
, pp. 541-549
-
-
Defronzo, R.A.1
Goodman, A.M.2
-
3
-
-
0032929173
-
Efficacy of metformin in the treatment of NIDDM: A metanalysis
-
Johansen, K. Efficacy of metformin in the treatment of NIDDM: a metanalysis. Diabetes Care 1999, 22, 33-37.
-
(1999)
Diabetes Care
, vol.22
, pp. 33-37
-
-
Johansen, K.1
-
4
-
-
0029132285
-
Worldwide experience of metformin as an effective glucose lowering agent: A metanalysis
-
Campbell, I.W.; Howlett, H.C.S. Worldwide experience of metformin as an effective glucose lowering agent: a metanalysis. Diabetes Metab. Rev. 1995, 11, 57-62.
-
(1995)
Diabetes Metab. Rev
, vol.11
, pp. 57-62
-
-
Campbell, I.W.1
Howlett, H.C.S.2
-
5
-
-
68449094325
-
The influence of glucose-lowering therapies on cancer risk in type 2 diabetes
-
Currie, C.J.; Poole, C.D.; Gale, E.A. The influence of glucose-lowering therapies on cancer risk in type 2 diabetes. Diabetologia 2009, 52, 1766-1777.
-
(2009)
Diabetologia
, vol.52
, pp. 1766-1777
-
-
Currie, C.J.1
Poole, C.D.2
Gale, E.A.3
-
6
-
-
34548658535
-
Metformin, heart failure, and lactic acidosis: Is metformin absolutely contraindicated?
-
Tahrani, A.A.; Varughese, G.I.; Scarpello, J.H.; Hanna, F.W. Metformin, heart failure, and lactic acidosis: is metformin absolutely contraindicated? Br. Med. J. 2007, 335, 508-512.
-
(2007)
Br. Med. J
, vol.335
, pp. 508-512
-
-
Tahrani, A.A.1
Varughese, G.I.2
Scarpello, J.H.3
Hanna, F.W.4
-
7
-
-
0034659785
-
Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain
-
Owen, M.R.; Doran, E.; Halestrap, A.P. Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain. Biochem. J. 2000, 348, 607-614.
-
(2000)
Biochem. J
, vol.348
, pp. 607-614
-
-
Owen, M.R.1
Doran, E.2
Halestrap, A.P.3
-
8
-
-
44649110211
-
Reality of severe metformin-induced lactic acidosis in the absence of chronic renal impairment
-
Bruijstens, L.A.; van Luin, M.; Buscher-Jungerhans, P.M.M; Bosch, F.H. Reality of severe metformin-induced lactic acidosis in the absence of chronic renal impairment. Netherlands J. Med. 2008, 66, 185-190.
-
(2008)
Netherlands J. Med
, vol.66
, pp. 185-190
-
-
Bruijstens, L.A.1
van Luin, M.2
Buscher-Jungerhans, P.M.M.3
Bosch, F.H.4
-
9
-
-
24044478791
-
Metformin contraindications should be contraindicated
-
McCormack, J.; Johns, K.; Tildesley, H. Metformin contraindications should be contraindicated. Ca. Med. Ass. J. 2005, 173, 502-504.
-
(2005)
Ca. Med. Ass. J
, vol.173
, pp. 502-504
-
-
McCormack, J.1
Johns, K.2
Tildesley, H.3
-
10
-
-
0029024314
-
Cloning the ß cell high-affinity sulfonylurea receptor: A regulator of insulin secretion
-
Aguilar-Bryan, L.; Nichols, C.G.; Wechsler, S.W.; Clement, J.P.; Boyd, A.E.; González, G.; Herrera-Sosa, H,; Nguy, K.; Bryan, J.; Nelson, D.A. Cloning the ß cell high-affinity sulfonylurea receptor: A regulator of insulin secretion. Science 1995, 268, 423-426.
-
(1995)
Science
, vol.268
, pp. 423-426
-
-
Aguilar-Bryan, L.1
Nichols, C.G.2
Wechsler, S.W.3
Clement, J.P.4
Boyd, A.E.5
González, G.6
Herrera-Sosa, H.7
Nguy, K.8
Bryan, J.9
Nelson, D.A.10
-
11
-
-
0031396662
-
Pharmacological regulation of blood glucose levels in non-insulindependent diabetes mellitus
-
Bressler, R.; Johnson, D.G. Pharmacological regulation of blood glucose levels in non-insulindependent diabetes mellitus. Arch. Intern. Med. 1997, 157, 836-848.
-
(1997)
Arch. Intern. Med
, vol.157
, pp. 836-848
-
-
Bressler, R.1
Johnson, D.G.2
-
12
-
-
0030974812
-
Prospective randomized study of intensive insulin treatment on long term survival after acute myocardial infarction in patients with diabetes mellitus
-
The DIGAMI Study Group
-
Malmberg, K.; The DIGAMI Study Group. Prospective randomized study of intensive insulin treatment on long term survival after acute myocardial infarction in patients with diabetes mellitus. Br. Med. J. 1997, 314, 1512-1515.
-
(1997)
Br. Med. J
, vol.314
, pp. 1512-1515
-
-
Malmberg, K.1
-
13
-
-
34948847587
-
Are sulphonylureas all the same? A cohort study on cardiovascular and cancerrelated mortality
-
Monami, M.; Balzi, D.; Lamanna, C.; Barchielli, A.; Masotti, G.; Buiatti, E.; Marchionni, N.; Mannucci, E. Are sulphonylureas all the same? A cohort study on cardiovascular and cancerrelated mortality. Diabetes Metab. Res. Rev. 2007, 23, 479-484.
-
(2007)
Diabetes Metab. Res. Rev
, vol.23
, pp. 479-484
-
-
Monami, M.1
Balzi, D.2
Lamanna, C.3
Barchielli, A.4
Masotti, G.5
Buiatti, E.6
Marchionni, N.7
Mannucci, E.8
-
14
-
-
0032511583
-
Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)
-
United Kingdom Prospective Diabetes Study (UKPDS) Group, (Published erratum appears in Lancet 1999, 354, 602)
-
United Kingdom Prospective Diabetes Study (UKPDS) Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 1998, 352, 837-853, (Published erratum appears in Lancet 1999, 354, 602).
-
(1998)
Lancet
, vol.837-853
, pp. 352
-
-
-
15
-
-
45149133036
-
Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes
-
ADVANCE Collaborative Group
-
ADVANCE Collaborative Group; Patel, A.; MacMahon, S.; Chalmers, J.; Neal, B., Billot, L.; Woodward, M.; Marre, M.; Cooper, M.; Glasziou, P.; Grobbee, D.; Hamet, P.; Harrap, S.; Heller, S.; Liu, L.; Mancia, G.; Mogensen, C.E.; Pan, C.; Poulter, N.; Rodgers, A.; Williams, B.; Bompoint, S.; de Galan, B.E.; Joshi. R.; Travert, F. Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes. N. Eng.l J. Med. 2008, 358, 2560-2572.
-
(2008)
N. Eng.l J. Med
, vol.358
, pp. 2560-2572
-
-
Patel, A.1
MacMahon, S.2
Chalmers, J.3
Neal, B.4
Billot, L.5
Woodward, M.6
Marre, M.7
Cooper, M.8
Glasziou, P.9
Grobbee, D.10
Hamet, P.11
Harrap, S.12
Heller, S.13
Liu, L.14
Mancia, G.15
Mogensen, C.E.16
Pan, C.17
Poulter, N.18
Rodgers, A.19
Williams, B.20
Bompoint, S.21
de Galan, B.E.22
more..
-
16
-
-
0033578476
-
Pharmacologic therapy for type 2 diabetes mellitus
-
DeFronzo, R.A. Pharmacologic therapy for type 2 diabetes mellitus. Ann. Intern. Med. 1999, 131, 281-303.
-
(1999)
Ann. Intern. Med
, vol.131
, pp. 281-303
-
-
Defronzo, R.A.1
-
17
-
-
70449360911
-
Combined effects of routine blood pressure lowering and intensive glucose control on macrovascular and microvascular outcomes in patients with type 2 diabetes: New results from ADVANCE trial
-
ADVANCE Collaborative Group; Cass, A.; Glasziou, P.; Harrap, S.; Lisheng, L.; Mancia, G.; Pillai, A.; Poulter, N.; Perkovic, V.; Travert, F
-
Zoungas, S.; de Galan, B.E.; Ninomiya, T.; Grobbee, D.; Hamet, P.; Heller, S.; MacMahon, S.; Marre, M.; Neal, B.; Patel, A.; Woodward, M.; Chalmers, J, ADVANCE Collaborative Group; Cass, A.; Glasziou, P.; Harrap, S.; Lisheng, L.; Mancia, G.; Pillai, A.; Poulter, N.; Perkovic, V.; Travert, F. Combined effects of routine blood pressure lowering and intensive glucose control on macrovascular and microvascular outcomes in patients with type 2 diabetes: New results from ADVANCE trial. Diabetes Care 2009, 32, 2068-2074.
-
(2009)
Diabetes Care
, vol.32
, pp. 2068-2074
-
-
Zoungas, S.1
de Galan, B.E.2
Ninomiya, T.3
Grobbee, D.4
Hamet, P.5
Heller, S.6
MacMahon, S.7
Marre, M.8
Neal, B.9
Patel, A.10
Woodward, M.11
Chalmers, J.12
-
18
-
-
0028019713
-
Glibenclamide Vs gliclazide in type 2 diabetes of the elderly
-
Tessier, D.; Dawson, K.; Tetrault, J.P.; Bravo, G.; Meneilly, G.S. Glibenclamide vs gliclazide in type 2 diabetes of the elderly. Diabet. Med. 1994, 11, 974-980.
-
(1994)
Diabet. Med
, vol.11
, pp. 974-980
-
-
Tessier, D.1
Dawson, K.2
Tetrault, J.P.3
Bravo, G.4
Meneilly, G.S.5
-
19
-
-
0031892659
-
Stimulation of insulin release by repaglinide and glibenclamide involves both common and distinct processes
-
Fuhlendorff, J.; Rorsman, P.; Kofod, H.; Brand, C.L,; Rolin, B.; MacKay, P.; Shymko, R.; Carr, R.D. Stimulation of insulin release by repaglinide and glibenclamide involves both common and distinct processes. Diabetes 1998, 47, 345-351.
-
(1998)
Diabetes
, vol.47
, pp. 345-351
-
-
Fuhlendorff, J.1
Rorsman, P.2
Kofod, H.3
Brand, C.L.4
Rolin, B.5
Mackay, P.6
Shymko, R.7
Carr, R.D.8
-
20
-
-
35448978003
-
Meglitinide analogues for type 2 diabetes mellitus
-
Black, O.; Donnelly, P.; McIntyre, L.; Royle, P.L.; Shepherd, J.P., Thomas, S. Meglitinide analogues for type 2 diabetes mellitus. Cochrane Database Syst. Rev. 2007, 2, CD004654.
-
(2007)
Cochrane Database Syst. Rev
, vol.2
-
-
Black, O.1
Donnelly, P.2
McIntyre, L.3
Royle, P.L.4
Shepherd, J.P.5
Thomas, S.6
-
21
-
-
0037579664
-
Multinational Repaglinide Renal Study Group. Safety and efficacy of repaglinide in type 2 diabetic patients with and without impaired renal function
-
Hasslacher, C. Multinational Repaglinide Renal Study Group. Safety and efficacy of repaglinide in type 2 diabetic patients with and without impaired renal function. Diabetes Care 2003, 26, 886-891.
-
(2003)
Diabetes Care
, vol.26
, pp. 886-891
-
-
Hasslacher, C.1
-
22
-
-
19244365650
-
Drug Therapy: Thiazolidinediones
-
Yki-Jarvinen, H. Drug Therapy: Thiazolidinediones. N. Engl. J. Med. 2004, 351, 1106-1118.
-
(2004)
N. Engl. J. Med
, vol.351
, pp. 1106-1118
-
-
Yki-Jarvinen, H.1
-
23
-
-
0034033388
-
Mechanism of troglitazone action in type 2 diabetes
-
Petersen, K.F.; Krssak, M.; Inzucchi, S.; Cline, G.W.; Dufour, S.; Shulman, G.I. Mechanism of troglitazone action in type 2 diabetes. Diabetes 2000, 49, 827-831.
-
(2000)
Diabetes
, vol.49
, pp. 827-831
-
-
Petersen, K.F.1
Krssak, M.2
Inzucchi, S.3
Cline, G.W.4
Dufour, S.5
Shulman, G.I.6
-
24
-
-
33846964860
-
Effects of chronic rosiglitazone therapy on gene expression in human adipose tissue in vivo in patients with type 2 diabetes
-
Kolak, M.; Yki-Jarvinen, H.; Kannisto, K. Effects of chronic rosiglitazone therapy on gene expression in human adipose tissue in vivo in patients with type 2 diabetes. J. Clin. Endocrinol. Metab. 2007, 92, 720-724.
-
(2007)
J. Clin. Endocrinol. Metab
, vol.92
, pp. 720-724
-
-
Kolak, M.1
Yki-Jarvinen, H.2
Kannisto, K.3
-
25
-
-
0030977450
-
Peroxisome proliferator-activated receptor gene expression in human tissues. Effects of obesity, weight loss, and regulation by insulin and glucocorticoids
-
Vidal-Puig, A.J.; Considine, R.V.; Jimenez-Linan, M.; Werman, A.; Pories, W.J.; Caro, J.F.; Flier, J.S. Peroxisome proliferator-activated receptor gene expression in human tissues. Effects of obesity, weight loss, and regulation by insulin and glucocorticoids. J. Clin. Invest. 1997, 99, 2416-2422.
-
(1997)
J. Clin. Invest
, vol.99
, pp. 2416-2422
-
-
Vidal-Puig, A.J.1
Considine, R.V.2
Jimenez-Linan, M.3
Werman, A.4
Pories, W.J.5
Caro, J.F.6
Flier, J.S.7
-
26
-
-
0004473133
-
PPARgamma Gene Expression is Elevated In Skeletal Muscle of Obese and Type II Diabetic Subjects
-
Park, K.S.; Ciaraldi, T.P.; Abrams-Carter, L.; Mudaliar, S.; Nikoulina, S.E.; Henry, R.R. PPARgamma Gene Expression is Elevated In Skeletal Muscle of Obese and Type II Diabetic Subjects. Diabetes 1997, 46, 1230-1234.
-
(1997)
Diabetes
, vol.46
, pp. 1230-1234
-
-
Park, K.S.1
Ciaraldi, T.P.2
Mudaliar, S.3
Nikoulina, S.E.4
Henry, R.R.5
-
27
-
-
33847006604
-
Review: Peroxisome proliferator-activated receptor gamma and adipose tissue--understanding obesity-related changes in regulation of lipid and glucose metabolism
-
Sharma, A.M.; Staels, B. Review: Peroxisome proliferator-activated receptor gamma and adipose tissue--understanding obesity-related changes in regulation of lipid and glucose metabolism. J. Clin. Endocrinol. Metab. 2007, 92, 386-395.
-
(2007)
J. Clin. Endocrinol. Metab
, vol.92
, pp. 386-395
-
-
Sharma, A.M.1
Staels, B.2
-
28
-
-
28144451163
-
Effect of muraglitazar on death and major adverse cardiovascular events in patients with type 2 diabetes mellitus
-
Nissen, S.E.; Wolski, K.; Topol, E.J. Effect of muraglitazar on death and major adverse cardiovascular events in patients with type 2 diabetes mellitus. JAMA 2005, 294, 2581-2586.
-
(2005)
JAMA
, vol.294
, pp. 2581-2586
-
-
Nissen, S.E.1
Wolski, K.2
Topol, E.J.3
-
29
-
-
67649839953
-
Effect of the dual peroxisome proliferator-activated receptor-alpha/gamma agonist aleglitazar on risk of cardiovascular disease in patients with type 2 diabetes (SYNCHRONY): A phase II, randomised, dose-ranging study
-
Henry, R.R.; Lincoff, A.M.; Mudaliar, S.; Rabbia, M.; Chognot, C.; Herz, M.; Effect of the dual peroxisome proliferator-activated receptor-alpha/gamma agonist aleglitazar on risk of cardiovascular disease in patients with type 2 diabetes (SYNCHRONY): a phase II, randomised, dose-ranging study. Lancet 2009, 374, 126-135.
-
(2009)
Lancet
, vol.374
, pp. 126-135
-
-
Henry, R.R.1
Lincoff, A.M.2
Mudaliar, S.3
Rabbia, M.4
Chognot, C.5
Herz, M.6
-
30
-
-
33847403059
-
A randomized trial of the effects of rosiglitazone and metformin on inflammation and subclinical atherosclerosis in patients with type 2 diabetes
-
Stocker, D.J.; Taylor, A.J.; Langley, R.W.; Jezior, M.R.; Vigersky, R.A. A randomized trial of the effects of rosiglitazone and metformin on inflammation and subclinical atherosclerosis in patients with type 2 diabetes. Am. Heart J. 2007, 153, 445.e1-6.
-
(2007)
Am. Heart J
, vol.153
, Issue.445
-
-
Stocker, D.J.1
Taylor, A.J.2
Langley, R.W.3
Jezior, M.R.4
Vigersky, R.A.5
-
31
-
-
33845400193
-
Effect of pioglitazone compared with glimepiride on carotid intima-media thickness in type 2 diabetes: A randomized trial
-
Mazzone, T.; Meyer, P.M.; Feinstein, S.B.; Davidson, M.H.; Kondos, G.T.; D'Agostino, R.B.; Sr, Perez, A.; Provost, J.C.; Haffner, S.M.;Effect of pioglitazone compared with glimepiride on carotid intima-media thickness in type 2 diabetes: a randomized trial. JAMA 2006, 296, 2572-2581.
-
(2006)
JAMA
, vol.296
, pp. 2572-2581
-
-
Mazzone, T.1
Meyer, P.M.2
Feinstein, S.B.3
Davidson, M.H.4
Kondos, G.T.5
D'Agostino, R.B.6
Provost, J.C.7
Haffner, S.M.8
-
32
-
-
33846961821
-
Differential effects of oral hypoglycemic agents on glucose control and cardiovascular risk
-
Uwaifo, G.I.; Ratner, R.E. Differential effects of oral hypoglycemic agents on glucose control and cardiovascular risk. Am. J. Cardiol. 2007, 99, 51B-67B.
-
(2007)
Am. J. Cardiol
, vol.99
-
-
Uwaifo, G.I.1
Ratner, R.E.2
-
33
-
-
41649084422
-
PERISCOPE Investigators; Comparison of pioglitazone vs glimepiride on progression of coronary atherosclerosis in patients with type 2 diabetes: The PERISCOPE randomized controlled trial
-
Nissen, S.E.; Nicholls, S.J.; Wolski, K.; Nesto, R.; Kupfer, S.; Perez, A.; Jure, H.; De Larochellière, R.; Staniloae, C.S.; Mavromatis, K.; Saw, J., Hu, B.; Lincoff, A.M.; Tuzcu, E.M. PERISCOPE Investigators; Comparison of pioglitazone vs glimepiride on progression of coronary atherosclerosis in patients with type 2 diabetes: the PERISCOPE randomized controlled trial. JAMA 2008, 299, 1561-1573.
-
(2008)
JAMA
, vol.299
, pp. 1561-1573
-
-
Nissen, S.E.1
Nicholls, S.J.2
Wolski, K.3
Nesto, R.4
Kupfer, S.5
Perez, A.6
Jure, H.7
de Larochellière, R.8
Staniloae, C.S.9
Mavromatis, K.10
Saw, J.11
Hu, B.12
Lincoff, A.M.13
Tuzcu, E.M.14
-
34
-
-
34250212715
-
Effect of Rosiglitazone on the Risk of Myocardial Infarction and Death from Cardiovascular Causes
-
Nissen, S.E.; Wolski, K. Effect of Rosiglitazone on the Risk of Myocardial Infarction and Death from Cardiovascular Causes. N. Engl. J. Med. 2007, 356, 2457-2471.
-
(2007)
N. Engl. J. Med
, vol.356
, pp. 2457-2471
-
-
Nissen, S.E.1
Wolski, K.2
-
35
-
-
34548590934
-
Pioglitazone and risk of cardiovascular events in patients with type 2 diabetes mellitus: A meta-analysis of randomized trials
-
Lincoff, A.M.; Wolski, K.; Nicholls, S.J.; Nissen, S.E. Pioglitazone and risk of cardiovascular events in patients with type 2 diabetes mellitus: a meta-analysis of randomized trials. JAMA 2007, 298, 1180-1188.
-
(2007)
JAMA
, vol.298
, pp. 1180-1188
-
-
Lincoff, A.M.1
Wolski, K.2
Nicholls, S.J.3
Nissen, S.E.4
-
36
-
-
34548303246
-
The Rosiglitazone Story - Lessons from an FDA Advisory Committee Meeting
-
Rosen, C.J. The Rosiglitazone Story - Lessons from an FDA Advisory Committee Meeting. N. Engl. J. Med. 2007, 357, 844-846.
-
(2007)
N. Engl. J. Med
, vol.357
, pp. 844-846
-
-
Rosen, C.J.1
-
37
-
-
34548580881
-
Long-term risk of cardiovascular events with rosiglitazone: A meta-analysis
-
Singh, S. Long-term risk of cardiovascular events with rosiglitazone: a meta-analysis. JAMA 2007, 298, 1189-1195.
-
(2007)
JAMA
, vol.298
, pp. 1189-1195
-
-
Singh, S.1
-
38
-
-
34548330055
-
Rosiglitazone for type 2 diabetes mellitus
-
Art. No.: CD006063; doi: 10.1002/14651858.CD006063.pub2
-
Richter, B.; Bandeira-Echtler, E.; Bergerhoff, K.; Clar, C.; Ebrahim, S.H. Rosiglitazone for type 2 diabetes mellitus. Cochrane Database Syst. Rev. 2007, 3. Art. No.: CD006063; doi: 10.1002/14651858.CD006063.pub2.
-
(2007)
Cochrane Database Syst. Rev
, pp. 3
-
-
Richter, B.1
-
39
-
-
35848930559
-
Uncertain effects of rosiglitazone on the risk for myocardial infarction and cardiovascular death
-
Diamond, G.A.; Bax, L.; Kaul, S. Uncertain effects of rosiglitazone on the risk for myocardial infarction and cardiovascular death. Ann. Intern. Med. 2007, 147, 578-581.
-
(2007)
Ann. Intern. Med
, vol.147
, pp. 578-581
-
-
Diamond, G.A.1
Bax, L.2
Kaul, S.3
-
40
-
-
24944569269
-
Rosiglitazone Evaluated for Cardiac Outcomes and Regulation of Glycaemia in Diabetes (RECORD): Study design and protocol
-
Home, P.D.; Pocock, S.J.; Beck-Nielsen, H.; Gomis, R.; Hanefeld, M.; Dargie, H.; Komajda, M.; Gubb, J.; Biswas, N.; Jones, N.P. Rosiglitazone Evaluated for Cardiac Outcomes and Regulation of Glycaemia in Diabetes (RECORD): study design and protocol. Diabetologia 2005, 48, 1726-1735.
-
(2005)
Diabetologia
, vol.48
, pp. 1726-1735
-
-
Home, P.D.1
Pocock, S.J.2
Beck-Nielsen, H.3
Gomis, R.4
Hanefeld, M.5
Dargie, H.6
Komajda, M.7
Gubb, J.8
Biswas, N.9
Jones, N.P.10
-
41
-
-
67149146438
-
RECORD Study Team;Rosiglitazone evaluated for cardiovascular outcomes in oral agent combination therapy for type 2 diabetes (RECORD): A multicentre, randomised, open-label trial
-
Home, P.D.; Pocock, S.J.; Beck-Nielsen, H.; Curtis, P.S.; Gomis, R.; Hanefeld, M.; Jones, N.P.; Komajda, M.; McMurray, J.J. RECORD Study Team;Rosiglitazone evaluated for cardiovascular outcomes in oral agent combination therapy for type 2 diabetes (RECORD): a multicentre, randomised, open-label trial. Lancet 2009, 373, 2125-2135.
-
(2009)
Lancet
, vol.373
, pp. 2125-2135
-
-
Home, P.D.1
Pocock, S.J.2
Beck-Nielsen, H.3
Curtis, P.S.4
Gomis, R.5
Hanefeld, M.6
Jones, N.P.7
Komajda, M.8
McMurray, J.J.9
-
42
-
-
26244453309
-
PROactive investigators; Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): A randomised controlled trial
-
Dormandy, J.A.; Charbonnel, B.; Eckland, D.J.; Erdmann, E.; Massi-Benedetti, M.; Moules, I.K.; Skene, A.M.; Tan, M.H.; Lefèbvre, P.J.; Murray, G.D.; Standl, E.; Wilcox, R.G.; Wilhelmsen, L.; Betteridge, J.; Birkeland, K.; Golay, A.; Heine, R.J.; Korányi, L.; Laakso, M.; Mokán, M.; Norkus, A.; Pirags, V.; Podar, T.; Scheen, A.; Scherbaum, W.; Schernthaner, G.; Schmitz, O.; Skrha, J.; Smith, U.; Taton, J. PROactive investigators; Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): A randomised controlled trial. Lancet 2005, 366, 1279-1289.
-
(2005)
Lancet
, vol.366
, pp. 1279-1289
-
-
Dormandy, J.A.1
Charbonnel, B.2
Eckland, D.J.3
Erdmann, E.4
Massi-Benedetti, M.5
Moules, I.K.6
Skene, A.M.7
Tan, M.H.8
Lefèbvre, P.J.9
Murray, G.D.10
Standl, E.11
Wilcox, R.G.12
Wilhelmsen, L.13
Betteridge, J.14
Birkeland, K.15
Golay, A.16
Heine, R.J.17
Korányi, L.18
Laakso, M.19
Mokán, M.20
Norkus, A.21
Pirags, V.22
Podar, T.23
Scheen, A.24
Scherbaum, W.25
Schernthaner, G.26
Schmitz, O.27
Skrha, J.28
Smith, U.29
Taton, J.30
more..
-
43
-
-
23844472901
-
Thiazolidinediones expand body fluid volume through PPARgamma stimulation of ENaC-mediated renal salt absorption
-
Guan, Y.; Hao, C.; Cha, D.R. Thiazolidinediones expand body fluid volume through PPARgamma stimulation of ENaC-mediated renal salt absorption. Nat. Med. 2005, 11, 861-866.
-
(2005)
Nat. Med
, vol.11
, pp. 861-866
-
-
Guan, Y.1
Hao, C.2
Cha, D.R.3
-
44
-
-
33845405222
-
Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy
-
Kahn, S.E.; Haffner, S.M.; Heise, M.A.; Rao, R.; Lu, W.; Kohan, D.E.; Magnuson, M.A.; Redha, R.; Zhang, Y.; Breyer, M.D. Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy. N. Engl. J. Med. 2006, 355, 2427-2443.
-
(2006)
N. Engl. J. Med
, vol.355
, pp. 2427-2443
-
-
Kahn, S.E.1
Haffner, S.M.2
Heise, M.A.3
Rao, R.4
Lu, W.5
Kohan, D.E.6
Magnuson, M.A.7
Redha, R.8
Zhang, Y.9
Breyer, M.D.10
-
45
-
-
0027947449
-
The efficacy of acarbose in the treatment of patients with non-insulindependent diabetes mellitus. A multicenter controlled clinical trial
-
Chiasson, J.L.; Josse, R.G.; Hunt, J.A.; Palmason, C.; Rodger, N.W.; Ross, S.A.; Ryan, E.A.; Tan, M.H.; Wolever, T.M. The efficacy of acarbose in the treatment of patients with non-insulindependent diabetes mellitus. A multicenter controlled clinical trial. Ann. Intern. Med. 1994, 121, 928-935.
-
(1994)
Ann. Intern. Med
, vol.121
, pp. 928-935
-
-
Chiasson, J.L.1
Josse, R.G.2
Hunt, J.A.3
Palmason, C.4
Rodger, N.W.5
Ross, S.A.6
Ryan, E.A.7
Tan, M.H.8
Wolever, T.M.9
-
46
-
-
63849220179
-
Incretin-Based Therapies in Type 2 Diabetes Mellitus
-
Chee, W.; Egan, C.; Egan, J.M. Incretin-Based Therapies in Type 2 Diabetes Mellitus. Curr. Protein Pept. Sci. 2009, 10, 46-55.
-
(2009)
Curr. Protein Pept. Sci
, vol.10
, pp. 46-55
-
-
Chee, W.1
Egan, C.2
Egan, J.M.3
-
47
-
-
0032982267
-
Role of the vagus nerve in mediating proximal nutrient-induced glucagon-like peptide-1 secretion
-
Rocca, A.S.; Brubaker, P.L. Role of the vagus nerve in mediating proximal nutrient-induced glucagon-like peptide-1 secretion. Endocrinology 1999, 140, 1687-1694.
-
(1999)
Endocrinology
, vol.140
, pp. 1687-1694
-
-
Rocca, A.S.1
Brubaker, P.L.2
-
48
-
-
22744442874
-
Type 2 diabetes--therapy with dipeptidyl peptidase IV inhibitors
-
Demuth, H.U.; McIntosh, C.H.; Pederson, R.A. Type 2 diabetes--therapy with dipeptidyl peptidase IV inhibitors. Biochim. Biophys. Acta 2005, 1751, 33-34.
-
(2005)
Biochim. Biophys. Acta
, vol.1751
, pp. 33-34
-
-
Demuth, H.U.1
McIntosh, C.H.2
Pederson, R.A.3
-
49
-
-
0036323269
-
Insulinotropic hormone glucagon-like peptide-1 differentiation of human pancreatic islet-derived progenitor cells into insulin-producing cells
-
Abraham, E.J.; Leech, C.A.; Lin, J.C.; Zulewski, H.; Habener, J.F. Insulinotropic hormone glucagon-like peptide-1 differentiation of human pancreatic islet-derived progenitor cells into insulin-producing cells. Endocrinology 2002, 143, 3152-3161.
-
(2002)
Endocrinology
, vol.143
, pp. 3152-3161
-
-
Abraham, E.J.1
Leech, C.A.2
Lin, J.C.3
Zulewski, H.4
Habener, J.F.5
-
50
-
-
33644618433
-
The biology of incretin hormones
-
Drucker, D.J. The biology of incretin hormones. Cell. Metab. 2006, 3, 153-65.
-
(2006)
Cell. Metab
, vol.3
, pp. 153-165
-
-
Drucker, D.J.1
-
51
-
-
0038497464
-
Synthetic exendin-4 (exenatide) significantly reduces postprandial and fasting plasma glucose in subjects with type 2 diabetes
-
Kolterman, O.G.; Buse, J.B.; Fineman, M.S.; Gaines, E.; Heintz, S.; Bicsak, T.A.; Taylor, K.; Kim, D.; Aisporna, M.; Wang, Y.; Baron, A.D.; Synthetic exendin-4 (exenatide) significantly reduces postprandial and fasting plasma glucose in subjects with type 2 diabetes. J. Clin. Endocrinol. Metab. 2003, 88, 3082-3089.
-
(2003)
J. Clin. Endocrinol. Metab
, vol.88
, pp. 3082-3089
-
-
Kolterman, O.G.1
Buse, J.B.2
Fineman, M.S.3
Gaines, E.4
Heintz, S.5
Bicsak, T.A.6
Taylor, K.7
Kim, D.8
Aisporna, M.9
Wang, Y.10
Baron, A.D.11
-
52
-
-
68949159829
-
Novel therapeutics for type 2 diabetes: Incretin hormone mimetics (glucagon-like peptide-1 receptor agonists) and dipeptidyl peptidase-4 inhibitors Pharmacol
-
Verspohl, E.J. Novel therapeutics for type 2 diabetes: Incretin hormone mimetics (glucagon-like peptide-1 receptor agonists) and dipeptidyl peptidase-4 inhibitors Pharmacol. Ther. 2009, 124, 113-138.
-
(2009)
Ther
, vol.124
, pp. 113-138
-
-
Verspohl, E.J.1
-
53
-
-
7444228521
-
Exenatide-113 Clinical Study Group; Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylureatreated patients with type 2 diabetes
-
Buse, J.B.; Henry, R.R.; Han, J.; Kim, D.D.; Fineman, M.S.; Baron, A.D. Exenatide-113 Clinical Study Group; Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylureatreated patients with type 2 diabetes. Diabetes Care 2004, 27, 2628-2635.
-
(2004)
Diabetes Care
, vol.27
, pp. 2628-2635
-
-
Buse, J.B.1
Henry, R.R.2
Han, J.3
Kim, D.D.4
Fineman, M.S.5
Baron, A.D.6
-
54
-
-
53249142132
-
DURATION-1 Study Group; Exenatide once weekly versus twice daily for the treatment of type 2 diabetes: A randomised, open-label, non-inferiority study
-
Drucker, D.J.; Buse, J.B.; Taylor, K.; Kendall, D.M.; Trautmann, M.; Zhuang, D.; Porter, L. DURATION-1 Study Group; Exenatide once weekly versus twice daily for the treatment of type 2 diabetes: a randomised, open-label, non-inferiority study. Lancet 2008, 372, 1240-1250.
-
(2008)
Lancet
, vol.372
, pp. 1240-1250
-
-
Drucker, D.J.1
Buse, J.B.2
Taylor, K.3
Kendall, D.M.4
Trautmann, M.5
Zhuang, D.6
Porter, L.7
-
55
-
-
26944477362
-
GWAA Study Group; Exenatide versus insulin glargine in patients with suboptimally controlled type 2 diabetes: A randomized trial
-
Heine, R.J.; Van Gaal, L.F.; Johns, D.; Mihm, M.J.; Widel, M.H.; Brodows, R.G. GWAA Study Group; Exenatide versus insulin glargine in patients with suboptimally controlled type 2 diabetes: a randomized trial. Ann. Intern. Med. 2005, 143, 559-569.
-
(2005)
Ann. Intern. Med
, vol.143
, pp. 559-569
-
-
Heine, R.J.1
van Gaal, L.F.2
Johns, D.3
Mihm, M.J.4
Widel, M.H.5
Brodows, R.G.6
-
56
-
-
18144401971
-
Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin treated patients with type 2 diabetes
-
De Fronzo, R.A.; Ratner, R.E.; Han, J.; Kim, D.D.; Fineman, M.S.; Baron, A.D. Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin treated patients with type 2 diabetes. Diabetes Care 2005, 28, 1092-1100.
-
(2005)
Diabetes Care
, vol.28
, pp. 1092-1100
-
-
de Fronzo, R.A.1
Ratner, R.E.2
Han, J.3
Kim, D.D.4
Fineman, M.S.5
Baron, A.D.6
-
57
-
-
77957312776
-
-
FDC reports
-
FDC reports. The Pink Sheet. 2008, 70, 9.
-
(2008)
The Pink Sheet
, vol.70
, pp. 9
-
-
-
58
-
-
0036066641
-
Bedtime administration of NN2211, a long-acting GLP-1 derivative, substantially reducesfasting and postprandial glycemia in type 2 diabetes
-
Juhl, C.B.; Hollingdal, M.; Sturis, J.; Jakobsen, G.; Agersø, H.; Veldhuis, J.; Pørksen, N.; Schmitz, O. Bedtime administration of NN2211, a long-acting GLP-1 derivative, substantially reducesfasting and postprandial glycemia in type 2 diabetes. Diabetes 2002, 51, 424-429.
-
(2002)
Diabetes
, vol.51
, pp. 424-429
-
-
Juhl, C.B.1
Hollingdal, M.2
Sturis, J.3
Jakobsen, G.4
Agersø, H.5
Veldhuis, J.6
Pørksen, N.7
Schmitz, O.8
-
59
-
-
34249891874
-
Effects of once-weekly dosing of a long-acting release formulation of exenatide on glucose control and body weight in subjects with type 2 diabetes
-
Kim, D.; MacConell, L.; Zhuang, D.; Kothare, P.A.; Trautmann, M.; Fineman, M.; Taylor, K. Effects of once-weekly dosing of a long-acting release formulation of exenatide on glucose control and body weight in subjects with type 2 diabetes. Diabetes Care 2007, 30, 1487-1493.
-
(2007)
Diabetes Care
, vol.30
, pp. 1487-1493
-
-
Kim, D.1
Macconell, L.2
Zhuang, D.3
Kothare, P.A.4
Trautmann, M.5
Fineman, M.6
Taylor, K.7
-
60
-
-
34447120048
-
Effect of renal insufficiency on the pharmacokinetics of sitagliptin, a dipeptidyl peptidase-4 inhibitor
-
Bergman, A.J.; Cote, J.; Yi, B.; Marbury, T.; Swan, S.K.; Smith, W.; Gottesdiener, K.; Wagner, J.; Herman, G.A. Effect of renal insufficiency on the pharmacokinetics of sitagliptin, a dipeptidyl peptidase-4 inhibitor. Diabetes Care 2007, 30, 1862-1864.
-
(2007)
Diabetes Care
, vol.30
, pp. 1862-1864
-
-
Bergman, A.J.1
Cote, J.2
Yi, B.3
Marbury, T.4
Swan, S.K.5
Smith, W.6
Gottesdiener, K.7
Wagner, J.8
Herman, G.A.9
-
61
-
-
33749993064
-
Multiple dose administration ofMK-0431 (sitagliptin), an inhibitor of dipeptidyl peptidase-IV, does not meaningfully alter the plasma pharmacokinetics or pharmacodynamics of single doses of warfarin
-
Wright, D.; Maes, A.L.; Yi, B.; Liu, Q.; Johnson-Levonas, A.O.; Wagner, J.A. Multiple dose administration ofMK-0431 (sitagliptin), an inhibitor of dipeptidyl peptidase-IV, does not meaningfully alter the plasma pharmacokinetics or pharmacodynamics of single doses of warfarin. Clin. Pharmacol. Ther. 2006, 79, 76-76.
-
(2006)
Clin. Pharmacol. Ther
, vol.79
, pp. 76-76
-
-
Wright, D.1
Maes, A.L.2
Yi, B.3
Liu, Q.4
Johnson-Levonas, A.O.5
Wagner, J.A.6
-
62
-
-
53049091868
-
Dipeptidyl peptidase-4 as a new target of action for type 2 diabetes mellitus: A systematic review
-
Wani, J.H.; John-Kalarickal, J.; Fonseca, V.A. Dipeptidyl peptidase-4 as a new target of action for type 2 diabetes mellitus: a systematic review. Cardiol. Clin. 2008, 26, 639-648.
-
(2008)
Cardiol. Clin
, vol.26
, pp. 639-648
-
-
Wani, J.H.1
John-Kalarickal, J.2
Fonseca, V.A.3
|