Magnetic resonance imaging study of hippocampus structural alterations in post-traumatic stress disorder: A brief review (translated version)

East Asian Archives of Psychiatry

Volumn 20, Issue 3, 2010, Pages 138-144

  Wang, Zhen ^a   Xiao, Ze Ping ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Hippocampus; Magnetic resonance imaging; Stress disorders, post traumatic

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; HYDROCORTISONE; PAROXETINE; SEROTONIN UPTAKE INHIBITOR; SERTRALINE;

BRAIN SIZE; CHRONIC STRESS; COGNITIVE THERAPY; CROSS-SECTIONAL STUDY; DENTATE GYRUS; HIPPOCAMPUS; HUMAN; HYDROCORTISONE BLOOD LEVEL; LONGITUDINAL STUDY; NERVOUS SYSTEM DEVELOPMENT; NEUROIMAGING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; POSTTRAUMATIC STRESS DISORDER; REVIEW;

EID: 77957309369     PISSN: 20789947     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (73)

1. Vasterling JJ, Duke LM, Brailey K, Constans JI, Allain AN Jr, Sutker PB. Attention, learning, and memory performances and intellectual resources in Vietnam veterans: PTSD and no disorder comparisons. Neuropsychology 2002;16:5-14.
2. Karl A, Malta LS, Maercker A. Meta-analytic review of event-related potential studies in post-traumatic stress disorder. Biol Psychol 2006;71:123-47.
3. Bannerman DM, Rawlins JN, McHugh SB, Deacon RM, Yee BK, Bast T, et al. Regional dissociations within the hippocampus - memory and anxiety. Neurosci Biobehav Rev 2004;28:273-83.
4. Whittle S, Allen NB, Lubman DI, Yücel M. The neurobiological basis of temperament: towards a better understanding of psychopathology. Neurosci Biobehav Rev 2006;30:511-25.
5. Phillips LJ, McGorry PD, Garner B, Thompson KN, Pantelis C, Wood SJ, et al. Stress, the hippocampus and the hypothalamic-pituitary-adrenal axis: implications for the development of psychotic disorders. Aust N Z J Psychiatry 2006;40:725-41.
6. Bremner JD, Randall P, Scott TM, Bronen RA, Seibyl JP, Southwick SM, et al. MRI-based measurement of hippocampal volume in patients with combat-related posttraumatic stress disorder. Am J Psychiatry 1995;152:973-81.
7. Bremner JD, Randall P, Vermetten E, Staib L, Bronen RA, Mazure C, et al. Magnetic resonance imaging-based measurement of hippocampal volume in posttraumatic stress disorder related to childhood physical and sexual abuse - a preliminary report. Biol Psychiatry 1997;41:23-32.
8. Stein MB, Koverola C, Hanna C, Torchia MG, McClarty B. Hippocampal volume in women victimized by childhood sexual abuse. Psychol Med 1997;27:951-9.
9. Villarreal G, Hamilton DA, Petropoulos H, Driscoll I, Rowland LM, Griego JA, et al. Reduced hippocampal volume and total white matter volume in posttraumatic stress disorder. Biol Psychiatry 2002;52:119-25.
10. Jatzko A, Rothenhöfer S, Schmitt A, Gaser C, Demirakca T, Weber-Fahr W, et al. Hippocampal volume in chronic posttraumatic stress disorder (PTSD): MRI study using two different evaluation methods. J Affect Disord 2006;94:121-6.
11. Hedges DW, Allen S, Tate DF, Thatcher GW, Miller MJ, Rice SA, et al. Reduced hippocampal volume in alcohol and substance naïve Vietnam combat veterans with posttraumatic stress disorder. Cogn Behav Neurol 2003;16:219-24.
12. Emdad R, Bonekamp D, Sondergaard HP, Bjorklund T, Agartz I, Ingvar M, et al. Morphometric and psychometric comparisons between non-substance-abusing patients with posttraumatic stress disorder and normal controls. Psychother Psychosom 2006;75:122-32. (Pubitemid 43313383)
13. Bossini L, Tavanti M, Calossi S, Lombardelli A, Polizzotto NR, Galli R, et al. Magnetic resonance imaging volumes of the hippocampus in drug-naive patients with post-traumatic stress disorder without comorbidity conditions. J Psychiatr Res 2008;42:752-62.
14. Pavić L, Gregurek R, Rados M, Brkljacić B, Brajković L, Simetin-Pavić I, et al. Smaller right hippocampus in war veterans with posttraumatic stress disorder. Psychiatry Res 2007;154:191-8.
15. Gurvits TV, Shenton ME, Hokama H, Ohta H, Lasko NB, Gilbertson MW, et al. Magnetic resonance imaging study of hippocampal volume in chronic, combat-related posttraumatic stress disorder. Biol Psychiatry 1996;40:192-9.
16. Lindauer RJ, Vlieger EJ, Jalink M, Olff M, Carlier IV, Majoie CB, et al. Smaller hippocampal volume in Dutch police officers with posttraumatic stress disorder. Biol Psychiatry 2004;56:356-63.
17. Winter H, Irle E. Hippocampal volume in adult burn patients with and without posttraumatic stress disorder. Am J Psychiatry 2004;161:2194-200.
18. Xiong YM, Hu ZY, Zhou YC, Xia LM, Wang CY, Shi QJ. MRI-based measurement of hippocampus volume in patients with post traumatic stress disorders [in Chinese]. Neural Injury and Functional Reconstruction 2007;2:96-9.
19. Weniger G, Lange C, Sachsse U, Irle E. Amygdala and hippocampal volumes and cognition in adult survivors of childhood abuse with dissociative disorders. Acta Psychiatr Scand 2008;118:281-90.
20. Felmingham K, Williams LM, Whitford TJ, Falconer E, Kemp AH, Peduto A, et al. Duration of posttraumatic stress disorder predicts hippocampal grey matter loss. Neuroreport 2009;20:1402-6.
21. Stein MB, Koverola C, Hanna C, Torchia MG, McClarty B. Hippocampal volume in women victimized by childhood sexual abuse. Psychol Med 1997;27:9519. (Pubitemid 27332181)
22. Shin LM, Shin PS, Heckers S, Krangel TS, Macklin ML, Orr SP, et al. Hippocampal function in posttraumatic stress disorder. Hippocampus 2004;14:292-300.
23. Wignall EL, Dickson JM, Vaughan P, Farrow TF, Wilkinson ID, Hunter MD, et al. Smaller hippocampal volume in patients with recent-onset posttraumatic stress disorder. Biol Psychiatry 2004;56:832-6.
24. Li L, Chen S, Liu J, Zhang J, He Z, Lin X. Magnetic resonance imaging and magnetic resonance spectroscopy study of deficits in hippocampal structure in fire victims with recent-onset posttraumatic stress disorder. Can J Psychiatry 2006;51:431-7.
25. Chen SL, Liu J, Li LJ, Xia WW, Hu DW, Zhang JL. A magnetic resonance imaging study of brain structure in post-traumatic stress disorder [in Chinese]. Chinese Journal of Psychiatry 2006;39:9-11.
26. Schuff N, Neylan TC, Lenoci MA, Du AT, Weiss DS, Marmar CR, et al. Decreased hippocampal N-acetylaspartate in the absence of atrophy in posttraumatic stress disorder. Biol Psychiatry 2001;50:952-9.
27. Schuff N, Neylan TC, Fox-Bosetti S, Lenoci M, Samuelson KW, Studholme C, et al. Abnormal N-acetylaspartate in hippocampus and anterior cingulate in posttraumatic stress disorder. Psychiatry Res 2008;162:147-57.
28. Fennema-Notestine C, Stein MB, Kennedy CM, Archibald SL, Jernigan TL. Brain morphometry in female victims of intimate partner violence with and without posttraumatic stress disorder. Biol Psychiatry 2002;52:1089-101.
29. Bremner JD, Vythilingam M, Vermetten E, Southwick SM, McGlashan T, Nazeer A, et al. MRI and PET study of deficits in hippocampal structure and function in women with childhood sexual abuse and posttraumatic stress disorder. Am J Psychiatry 2003;160:924-32.
30. Golier JA, Yehuda R, De Santi S, Segal S, Dolan S, de Leon MJ. Absence of hippocampal volume differences in survivors of the Nazi Holocaust with and without posttraumatic stress disorder. Psychiatry Res 2005;139:53-64.
31. Hara E, Matsuoka Y, Hakamata Y, Nagamine M, Inagaki M, Imoto S, et al. Hippocampal and amygdalar volumes in breast cancer survivors with posttraumatic stress disorder. J Neuropsychiatry Clin Neurosci 2008;20:302-8.
32. Nakano T, Wenner M, Inagaki M, Kugaya A, Akechi T, Matsuoka Y, et al. Relationship between distressing cancer-related recollections and hippocampal volume in cancer survivors. Am J Psychiatry 2002;159:2087-93.
33. Kitayama N, Vaccarino V, Kutner M, Weiss P, Bremner JD. Magnetic resonance imaging (MRI) measurement of hippocampal volume in posttraumatic stress disorder: a meta-analysis. J Affect Disord 2005;88:79-86.
34. Smith ME. Bilateral hippocampal volume reduction in adults with post-traumatic stress disorder: a meta-analysis of structural MRI studies. Hippocampus 2005;15:798-807.
35. Freeman TW, Cardwell D, Karson CN, Komoroski RA. In vivo proton magnetic resonance spectroscopy of the medial temporal lobes of subjects with combat-related posttraumatic stress disorder. Magn Reson Med 1998;40:66-71.
36. Gilbertson MW, Shenton ME, Ciszewski A, Kasai K, Lasko NB, Orr SP, et al. Smaller hippocampal volume predicts pathologic vulnerability to psychological trauma. Nat Neurosci 2002;5:1242-7. (Pubitemid 35247185)
37. Irle E, Lange C, Sachsse U. Reduced size and abnormal asymmetry of parietal cortex in women with borderline personality disorder. Biol Psychiatry 2005;57:173-82.
38. Lindauer RJ, Vlieger EJ, Jalink M, Olff M, Carlier IV, Majoie CB, et al. Effects of psychotherapy on hippocampal volume in out-patients with post-traumatic stress disorder: a MRI investigation. Psychol Med 2005;35:1421-31.
39. Mahmutyazicioǧlu K, Konuk N, Ozdemir H, Atasoy N, Atik L, Gündoǧdu S. Evaluation of the hippocampus and the anterior cingulate gyrus by proton MR spectroscopy in patients with post-traumatic stress disorder. Diagn Interv Radiol 2005;11:125-9.
40. Chen SL, Liu J, Li LJ, He Z, Zhang JL, Ma N, Gao XP. An in vivo MR spectroscopy imaging on hippocampus in patients with posttraumatic stress disorder [in Chinese]. Chinese Journal of Radiology 2006;40:594-6.
41. Felmingham K, Williams LM, Whitford TJ, Falconer E, Kemp AH, Peduto A, et al. Duration of posttraumatic stress disorder predicts hippocampal grey matter loss. Neuroreport 2009;20:1402-6.
42. Kasai K, Yamasue H, Gilbertson MW, Shenton ME, Rauch SL, Pitman RK. Evidence for acquired pregenual anterior cingulate gray matter loss from a twin study of combat-related post-traumatic stress disorder. Biol Psychiatry 2008;63:550-6.
43. Yehuda R, Golier JA, Tischler L, Harvey PD, Newmark R, Yang RK, et al. Hippocampal volume in aging combat veterans with and without post-traumatic stress disorder: relation to risk and resilience factors. J Psychiatr Res 2007;41:435-45.
44. Vermetten E, Vythilingam M, Southwick SM, Charney DS, Bremner JD. Long-term treatment with paroxetine increases verbal declarative memory and hippocampal volume in posttraumatic stress disorder. Biol Psychiatry 2003;54:693-702.
45. Bossini L, Tavanti M, Lombardelli A, Calossi S, Polizzotto NR, Galli R, et al. Changes in hippocampal volume in patients with post-traumatic stress disorder after sertraline treatment. J Clin Psychopharmacol 2007;27:233-5.
46. Cloitre M. Effective psychotherapies for posttraumatic stress disorder: a review and critique. CNS Spectr 2009; 14(1 Suppl 1):S32-43.
47. Kaufman J, Plotsky PM, Nemeroff CB, Charney DS. Effects of early adverse experiences on brain structure and function: clinical implications. Biol Psychiatry 2000;48:778-90.
48. De Bellis MD, Keshavan MS, Clark DB, Casey BJ, Giedd JN, Boring AM, et al. A.E. Bennett Research Award. Developmental traumatology. Part II: Brain development. Biol Psychiatry 1999;45:1271-84.
49. Karl A, Schaefer M, Malta LS, Dörfel D, Rohleder N, Werner A. A meta-analysis of structural brain abnormalities in PTSD. Neurosci Biobehav Rev 2006;30:1004-31.
50. Tupler LA, De Bellis MD. Segmented hippocampal volume in children and adolescents with posttraumatic stress disorder. Biol Psychiatry 2006;59:523-9.
51. Gogtay N, Nugent TF 3rd, Herman DH, Ordonez A, Greenstein D, Hayashi KM, et al. Dynamic mapping of normal human hippocampal development. Hippocampus 2006;16:664-72.
52. De Bellis MD, Baum AS, Birmaher B, Keshavan MS, Eccard CH, Boring AM, et al. A.E. Bennett Research Award. Developmental traumatology. Part I: Biological stress systems. Biol Psychiatry 1999;45:1259-70.
53. Carrion VG, Weems CF, Ray RD, Glaser B, Hessl D, Reiss AL. Diurnal salivary Cortisol in pediatric posttraumatic stress disorder. Biol Psychiatry 2002;51:575-82.
54. Vythilingam M, Luckenbaugh DA, Lam T, Morgan CA 3rd, Lipschitz D, Charney DS, et al. Smaller head of the hippocampus in Gulf War-related posttraumatic stress disorder. Psychiatry Res 2005;139:89-99.
55. Bonne O, Brandes D, Gilboa A, Gomori JM, Shenton ME, Pitman RK, et al. Longitudinal MRI study of hippocampal volume in trauma survivors with PTSD. Am J Psychiatry 2001;158:1248-51.
56. Duvernoy HM, Vannson JL, Cattin F, Naidich TP, Raybaud C, Risold PY, et al. The human hippocampus: functional anatomy, vascularization and serial sections with MRI. 3rd ed. New York: Springer-Verlag; 2005.
57. Wang Z, Neylan TC, Mueller SG, Lenoci M, Truran D, Marmar CR, et al. Magnetic resonance imaging of hippocampal subfields in posttraumatic stress disorder. Arch Gen Psychiatry 2010;67:296-303.
58. Cameron HA, McKay RD. Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus. J Comp Neurol 2001;435:406-17.
59. Kee N, Teixeira CM, Wang AH, Frankland PW. Preferential incorporation of adult-generated granule cells into spatial memory networks in the dentate gyrus. Nat Neurosci 2007;10:355-62. (Pubitemid 46310466)
60. Pham K, Nacher J, Hof PR, McEwen BS. Repeated restraint stress suppresses neurogenesis and induces biphasic PSA-NCAM expression in the adult rat dentate gyrus. Eur J Neurosci 2003;17:879-86.
61. Xu Y, Kong H, Song Q, Li Y. Effects of chronic stress on ability of spatial learning-memory and expression of brain derived neurotrophic factor in the hippocampus and prefrontal cortex of mice [in Chinese]. Journal of Qufu Normal University (Natural Science) 2009;46:85-9.
62. Jin HY, Liu SW, Yang Q, Zhang LH. Ultrastructural changes of dendrites of pyramidal neurons in hippocampal CA3 region of rats with chronic stress [in Chinese]. Chinese Journal of Clinical Rehabilitation 2005;9:76-7.
63. Magarinos AM, McEwen BS, Flügge G, Fuchs E. Chronic psychosocial stress causes apical dendritic atrophy of hippocampal CA3 pyramidal neurons in subordinate tree shrews. J Neurosci 1996;16:3534-40.
64. Takemura NU, Kato N. Adult neurogenesis and systemic adaptation: animal experiments and clinical perspectives for PTSD. Prog Brain Res 2008;167:99-109.
65. Cole J, Toga AW, Hojatkashani C, Thompson P, Costafreda SG, Cleare AJ, et al. Subregional hippocampal deformations in major depressive disorder. J Affect Disord 2010 Apr 13. Epub ahead of print.
66. Ebdrup BH, Glenthøj B, Rasmussen H, Aggernaes B, Langkilde AR, Paulson OB, et al. Hippocampal and caudate volume reductions in antipsychotic-naive first-episode schizophrenia. J Psychiatry Neurosci 2010;35:95-104.
67. Ewers M, Cheng X, Nural HF, Walsh C, Meindl T, Teipel SJ, et al. Increased CSF- BACE1 activity associated with decreased hippocampus volume in Alzheimer's disease. J Alzheimers Dis 2010 Apr 26. Epub ahead of print.
68. Vermetten E, Schmahl C, Lindner S, Loewenstein RJ, Bremner JD. Hippocampal and amygdalar volumes in dissociative identity disorder. Am J Psychiatry 2006;163:630-6. (Pubitemid 44464572)
69. Mueller SG, Schuff N, Raptentsetsang S, Elman J, Weiner MW Selective effect of Apo e4 on CA3 and dentate in normal aging and Alzheimer's disease using high resolution MRI at 4 T. Neuroimage 2008;42:42-8.
70. De Bellis MD, Hall J, Boring AM, Frustaci K, Moritz G. A pilot longitudinal study of hippocampal volumes in pediatric maltreatment-related posttraumatic stress disorder. Biol Psychiatry 2001;50:305-9.
71. Bonne O, Vythilingam M, Inagaki M, Wood S, Neumeister A, Nugent AC, et al. Reduced posterior hippocampal volume in posttraumatic stress disorder. J Clin Psychiatry 2008;69:1087-91.
72. Lui S, Huang X, Chen L, Tang H, Zhang T, Li X, et al. High-field MRI reveals an acute impact on brain function in survivors of the magnitude 8.0 earthquake in China. Proc Natl Acad Sci U S A 2009;106:15412-7.
73. Carrion VG, Weems CF, Reiss AL. Stress predicts brain changes in children: a pilot longitudinal study on youth stress, posttraumatic stress disorder, and the hippocampus. Pediatrics 2007;119:509-16.