메뉴 건너뛰기




Volumn 11, Issue 10, 2010, Pages 1469-1476

Neurosteroids and Self-Reported Pain in Veterans Who Served in the U.S. Military after September 11, 2001

Author keywords

Allopregnanolone; DHEA; Neuroactive Steroid; Neurosteroid; Nociception; Pain; Pregnenolone

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 4 AMINOBUTYRIC ACID A RECEPTOR; PRASTERONE; PRASTERONE SULFATE; PREGNENOLONE; PROGESTERONE;

EID: 77957245229     PISSN: 15262375     EISSN: 15264637     Source Type: Journal    
DOI: 10.1111/j.1526-4637.2010.00927.x     Document Type: Article
Times cited : (32)

References (71)
  • 1
    • 46849093902 scopus 로고    scopus 로고
    • and, Invisible Wounds Study Team, Rand Report, Santa Monica, CA, Center for Military Health Policy Research
    • Tanielian T, Jaycox LH, Schell TL. Invisible Wounds of War 2008, and, Invisible Wounds Study Team, Rand Report, Santa Monica, CA, Center for Military Health Policy Research
    • (2008) Invisible Wounds of War
    • Tanielian, T.1    Jaycox, L.H.2    Schell, T.L.3
  • 2
    • 10044273152 scopus 로고    scopus 로고
    • Casualties of war-Military care for the wounded from Iraq and Afghanistan
    • Gawande A. Casualties of war-Military care for the wounded from Iraq and Afghanistan. N Engl J Med 2004, 351(24):2471-5.
    • (2004) N Engl J Med , vol.351 , Issue.24 , pp. 2471-2475
    • Gawande, A.1
  • 3
    • 3042642128 scopus 로고    scopus 로고
    • Combat duty in Iraq and Afghanistan, mental health problems, and barriers to care
    • Hoge CW, Castro CA, Messer SC. Combat duty in Iraq and Afghanistan, mental health problems, and barriers to care. N Engl J Med 2004, 351(1):13-22.
    • (2004) N Engl J Med , vol.351 , Issue.1 , pp. 13-22
    • Hoge, C.W.1    Castro, C.A.2    Messer, S.C.3
  • 4
    • 38749111066 scopus 로고    scopus 로고
    • Mild traumatic brain injury in U.S. Soldiers returning from Iraq
    • Hoge CW, McGurk D, Thomas JL. Mild traumatic brain injury in U.S. Soldiers returning from Iraq. N Engl J Med 2008, 358(5):453-63.
    • (2008) N Engl J Med , vol.358 , Issue.5 , pp. 453-463
    • Hoge, C.W.1    McGurk, D.2    Thomas, J.L.3
  • 5
    • 33947251652 scopus 로고    scopus 로고
    • Bringing the war back home: Mental health disorders among 103,788 US veterans returning from Iraq and Afghanistan seen at Department of Veterans Affairs facilities
    • Seal KH, Bertenthal D, Miner CR, Sen S, Marmar C. Bringing the war back home: Mental health disorders among 103,788 US veterans returning from Iraq and Afghanistan seen at Department of Veterans Affairs facilities. Arch Int Med 2007, 167(5):476-82.
    • (2007) Arch Int Med , vol.167 , Issue.5 , pp. 476-482
    • Seal, K.H.1    Bertenthal, D.2    Miner, C.R.3    Sen, S.4    Marmar, C.5
  • 6
    • 33746288076 scopus 로고    scopus 로고
    • Pain among veterans of Operations Enduring Freedom and Iraqi Freedom
    • Gironda RJ, Clark ME, Massengale JP, Walker RL. Pain among veterans of Operations Enduring Freedom and Iraqi Freedom. Pain Med 2006, 7(4):339-43.
    • (2006) Pain Med , vol.7 , Issue.4 , pp. 339-343
    • Gironda, R.J.1    Clark, M.E.2    Massengale, J.P.3    Walker, R.L.4
  • 7
    • 73949110387 scopus 로고    scopus 로고
    • Chronic widespread pain, mental health, and physical role function in OEF/OIF veterans
    • Helmer DA, Chandler HK, Quigley KS. Chronic widespread pain, mental health, and physical role function in OEF/OIF veterans. Pain Med 2009, 10(7):1174-82.
    • (2009) Pain Med , vol.10 , Issue.7 , pp. 1174-1182
    • Helmer, D.A.1    Chandler, H.K.2    Quigley, K.S.3
  • 8
    • 0022483382 scopus 로고
    • Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor
    • Majewska MD, Harrison NL, Schwartz RD, Barker JL, Paul SM. Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor. Science 1986, 232(4753):1004-7.
    • (1986) Science , vol.232 , Issue.4753 , pp. 1004-1007
    • Majewska, M.D.1    Harrison, N.L.2    Schwartz, R.D.3    Barker, J.L.4    Paul, S.M.5
  • 9
    • 0023548049 scopus 로고
    • Steroid hormone metabolites potentiate GABA receptor-mediated chloride ion flux with nanomolar potency
    • Morrow AL, Suzdak PD, Paul SM. Steroid hormone metabolites potentiate GABA receptor-mediated chloride ion flux with nanomolar potency. Eur J Pharmacol 1987, 142(3):483-5.
    • (1987) Eur J Pharmacol , vol.142 , Issue.3 , pp. 483-485
    • Morrow, A.L.1    Suzdak, P.D.2    Paul, S.M.3
  • 10
    • 0023114555 scopus 로고
    • Pregnenolone-sulfate: An endogenous antagonist of the gamma-aminobutyric acid receptor complex in brain?
    • Majewska MD, Schwartz RD. Pregnenolone-sulfate: An endogenous antagonist of the gamma-aminobutyric acid receptor complex in brain? Brain Res 1987, 404(1-2):355-60.
    • (1987) Brain Res , vol.404 , Issue.1-2 , pp. 355-360
    • Majewska, M.D.1    Schwartz, R.D.2
  • 11
    • 0025149413 scopus 로고
    • Binding of pregnenolone sulfate to rat brain membranes suggests multiple sites of steroid action at the GABAA receptor
    • Majewska MD, Demirgoren S, London ED. Binding of pregnenolone sulfate to rat brain membranes suggests multiple sites of steroid action at the GABAA receptor. Eur J Pharmacol 1990, 189(4-5):307-15.
    • (1990) Eur J Pharmacol , vol.189 , Issue.4-5 , pp. 307-315
    • Majewska, M.D.1    Demirgoren, S.2    London, E.D.3
  • 12
    • 0025091447 scopus 로고
    • The neurosteroid dehydroepiandrosterone sulfate is an allosteric antagonist of the GABAA receptor
    • Majewska MD, Demirgoren S, Spivak CE, London ED. The neurosteroid dehydroepiandrosterone sulfate is an allosteric antagonist of the GABAA receptor. Brain Res 1990, 526(1):143-6.
    • (1990) Brain Res , vol.526 , Issue.1 , pp. 143-146
    • Majewska, M.D.1    Demirgoren, S.2    Spivak, C.E.3    London, E.D.4
  • 13
    • 0032562092 scopus 로고    scopus 로고
    • Modulation of GABA-gated chloride ion influx in the brain by dehydroepiandrosterone and its metabolites
    • Imamura M, Prasad C. Modulation of GABA-gated chloride ion influx in the brain by dehydroepiandrosterone and its metabolites. Biochem Biophys Res Commun 1998, 243(3):771-5.
    • (1998) Biochem Biophys Res Commun , vol.243 , Issue.3 , pp. 771-775
    • Imamura, M.1    Prasad, C.2
  • 14
    • 0033614716 scopus 로고    scopus 로고
    • Sulfated and unsulfated steroids modulate γ-aminobutyric acidA receptor function through distinct sites
    • Park-Chung M, Malayev A, Purdy RH, Gibbs TT, Farb DH. Sulfated and unsulfated steroids modulate γ-aminobutyric acidA receptor function through distinct sites. Brain Res 1999, 830(1):72-87.
    • (1999) Brain Res , vol.830 , Issue.1 , pp. 72-87
    • Park-Chung, M.1    Malayev, A.2    Purdy, R.H.3    Gibbs, T.T.4    Farb, D.H.5
  • 15
    • 0023022470 scopus 로고
    • Anxiolytic activity of an endogenous adrenal steroid
    • Crawley JN, Glowa JR, Majewska MD, Paul SM. Anxiolytic activity of an endogenous adrenal steroid. Brain Res 1986, 398(2):382-5.
    • (1986) Brain Res , vol.398 , Issue.2 , pp. 382-385
    • Crawley, J.N.1    Glowa, J.R.2    Majewska, M.D.3    Paul, S.M.4
  • 16
    • 0025987983 scopus 로고
    • Anxiolytic activity of the progesterone metabolite 5 α-pregnan-3 α-ol-20-one
    • Wieland S, Lan NC, Mirasedeghi S, Gee KW. Anxiolytic activity of the progesterone metabolite 5 α-pregnan-3 α-ol-20-one. Brain Res 1991, 565(2):263-8.
    • (1991) Brain Res , vol.565 , Issue.2 , pp. 263-268
    • Wieland, S.1    Lan, N.C.2    Mirasedeghi, S.3    Gee, K.W.4
  • 17
    • 0033873643 scopus 로고    scopus 로고
    • The neurosteroid pregnanolone prevents the anxiogenic-like effect of inescapable shock in the rat
    • Bitran D, Klibansky DA, Martin GA. The neurosteroid pregnanolone prevents the anxiogenic-like effect of inescapable shock in the rat. Psychopharmacology 2000, 151(1):31-7.
    • (2000) Psychopharmacology , vol.151 , Issue.1 , pp. 31-37
    • Bitran, D.1    Klibansky, D.A.2    Martin, G.A.3
  • 18
    • 16244367134 scopus 로고    scopus 로고
    • Reversal of caffeine-induced anxiety by neurosteroid 3-α-hydroxy-5-α-pregnane-20-one in rats
    • Jain NS, Hirani K, Chopde CT. Reversal of caffeine-induced anxiety by neurosteroid 3-α-hydroxy-5-α-pregnane-20-one in rats. Neuropharmacology 2005, 48(5):627-38.
    • (2005) Neuropharmacology , vol.48 , Issue.5 , pp. 627-638
    • Jain, N.S.1    Hirani, K.2    Chopde, C.T.3
  • 19
    • 0023608657 scopus 로고
    • The effect of progesterone and its metabolites on the interictal epileptiform discharge in the cat's cerebral cortex
    • Landgren S, Aasly J, Backstrom T, Dubrovsky B, Danielsson E. The effect of progesterone and its metabolites on the interictal epileptiform discharge in the cat's cerebral cortex. Acta Physiol Scand 1987, 131(1):33-42.
    • (1987) Acta Physiol Scand , vol.131 , Issue.1 , pp. 33-42
    • Landgren, S.1    Aasly, J.2    Backstrom, T.3    Dubrovsky, B.4    Danielsson, E.5
  • 20
    • 0024321145 scopus 로고
    • Anticonvulsant profile of the progesterone metabolite 5 α-pregnan-3 α-ol-20-one
    • Belelli D, Bolger MB, Gee KW. Anticonvulsant profile of the progesterone metabolite 5 α-pregnan-3 α-ol-20-one. Eur J Pharmacol 1989, 166(2):325-9.
    • (1989) Eur J Pharmacol , vol.166 , Issue.2 , pp. 325-329
    • Belelli, D.1    Bolger, M.B.2    Gee, K.W.3
  • 21
    • 0028149787 scopus 로고
    • Anticonvulsant activity of neurosteroids: Correlation with gamma-aminobutyric acid-evoked chloride current potentiation
    • Kokate TG, Svensson BE, Rogawski MA. Anticonvulsant activity of neurosteroids: Correlation with gamma-aminobutyric acid-evoked chloride current potentiation. J Pharmacol Exp Ther 1994, 270(3):1223-9.
    • (1994) J Pharmacol Exp Ther , vol.270 , Issue.3 , pp. 1223-1229
    • Kokate, T.G.1    Svensson, B.E.2    Rogawski, M.A.3
  • 22
    • 0028932249 scopus 로고
    • The neurosteroid, 3 α-hydroxy-5 α-pregnan-20-one, protects against bicuculline-induced seizures during ethanol withdrawal in rats
    • Devaud LL, Purdy RH, Morrow AL. The neurosteroid, 3 α-hydroxy-5 α-pregnan-20-one, protects against bicuculline-induced seizures during ethanol withdrawal in rats. Alcohol Clin Exp Res 1995, 19(2):350-5.
    • (1995) Alcohol Clin Exp Res , vol.19 , Issue.2 , pp. 350-355
    • Devaud, L.L.1    Purdy, R.H.2    Morrow, A.L.3
  • 23
    • 0030472538 scopus 로고    scopus 로고
    • Neuroactive steroids protect against pilocarpine- and kainic acid-induced limbic seizures and status epilepticus in mice
    • Kokate TG, Cohen AL, Karp E, Rogawski MA. Neuroactive steroids protect against pilocarpine- and kainic acid-induced limbic seizures and status epilepticus in mice. Neuropharmacology 1996, 35(8):1049-56.
    • (1996) Neuropharmacology , vol.35 , Issue.8 , pp. 1049-1056
    • Kokate, T.G.1    Cohen, A.L.2    Karp, E.3    Rogawski, M.A.4
  • 24
    • 0023809472 scopus 로고
    • Inhibitory influences of the adrenal steroid, 3 α, 5 α-tetrahydrodeoxycorticosterone (correction of tetrahydroxycorticosterone) on aggression and defeat-induced analgesia in mice
    • Kavaliers M. Inhibitory influences of the adrenal steroid, 3 α, 5 α-tetrahydrodeoxycorticosterone (correction of tetrahydroxycorticosterone) on aggression and defeat-induced analgesia in mice. Psychopharmacology 1988, 95(4):488-92.
    • (1988) Psychopharmacology , vol.95 , Issue.4 , pp. 488-492
    • Kavaliers, M.1
  • 25
    • 0037452699 scopus 로고    scopus 로고
    • In socially isolated mice, the reversal of brain allopregnanolone down-regulation mediates the anti-aggressive action of fluoxetine
    • Pinna G, Dong E, Matsumoto K, Costa E, Guidotti A. In socially isolated mice, the reversal of brain allopregnanolone down-regulation mediates the anti-aggressive action of fluoxetine. Proc Natl Acad Sci U S A 2003, 100(4):2035-40.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.4 , pp. 2035-2040
    • Pinna, G.1    Dong, E.2    Matsumoto, K.3    Costa, E.4    Guidotti, A.5
  • 26
    • 0023182380 scopus 로고
    • Analgesic effects of the progesterone metabolite, 3 α-hydroxy-5 α-pregnan-20-one, and possible modes of action in mice
    • Kavaliers M, Wiebe JP. Analgesic effects of the progesterone metabolite, 3 α-hydroxy-5 α-pregnan-20-one, and possible modes of action in mice. Brain Res 1987, 415(2):393-8.
    • (1987) Brain Res , vol.415 , Issue.2 , pp. 393-398
    • Kavaliers, M.1    Wiebe, J.P.2
  • 27
    • 0026501159 scopus 로고
    • Analgesic effects of intrathecally-administered 3 α-hydroxy-5 α-pregnan-20-one in a rat mechanical visceral pain model
    • Winfree CJ, Coombs DW, DeLeo JA, Colburn RW. Analgesic effects of intrathecally-administered 3 α-hydroxy-5 α-pregnan-20-one in a rat mechanical visceral pain model. Life Sci 1992, 50(14):1007-12.
    • (1992) Life Sci , vol.50 , Issue.14 , pp. 1007-1012
    • Winfree, C.J.1    Coombs, D.W.2    DeLeo, J.A.3    Colburn, R.W.4
  • 28
    • 0028329702 scopus 로고
    • Progesterone metabolites, effective at the GABAA receptor complex, attenuate pain sensitivity in rats
    • Frye CA, Duncan JE. Progesterone metabolites, effective at the GABAA receptor complex, attenuate pain sensitivity in rats. Brain Res 1994, 643(1-2):194-203.
    • (1994) Brain Res , vol.643 , Issue.1-2 , pp. 194-203
    • Frye, C.A.1    Duncan, J.E.2
  • 29
    • 0029895224 scopus 로고    scopus 로고
    • Allopregnanolone (THP) mediates anesthetic effects of progesterone in rat brain
    • Korneyev A, Costa E. Allopregnanolone (THP) mediates anesthetic effects of progesterone in rat brain. Horm Behav 1996, 30(1):37-43.
    • (1996) Horm Behav , vol.30 , Issue.1 , pp. 37-43
    • Korneyev, A.1    Costa, E.2
  • 30
    • 0032793381 scopus 로고    scopus 로고
    • Antinociceptive effects of the neuroactive steroid, 3α-hydroxy-5α-pregnan-20-one and progesterone in the land snail, Cepaea nemoralis
    • Kavaliers M, Perrot-Sinal TS, Desjardins DC, Cross-Mellor SK, Wiebe JP. Antinociceptive effects of the neuroactive steroid, 3α-hydroxy-5α-pregnan-20-one and progesterone in the land snail, Cepaea nemoralis. Neuroscience 2000, 95(3):807-12.
    • (2000) Neuroscience , vol.95 , Issue.3 , pp. 807-812
    • Kavaliers, M.1    Perrot-Sinal, T.S.2    Desjardins, D.C.3    Cross-Mellor, S.K.4    Wiebe, J.P.5
  • 31
    • 20144373040 scopus 로고    scopus 로고
    • New evidence that both T-type calcium channels and GABAA channels are responsible for the potent peripheral analgesic effects of 5α-reduced neuroactive steroids
    • Pathirathna S, Brimelow BC, Jagodic MM. New evidence that both T-type calcium channels and GABAA channels are responsible for the potent peripheral analgesic effects of 5α-reduced neuroactive steroids. Pain 2005, 114(3):429-43.
    • (2005) Pain , vol.114 , Issue.3 , pp. 429-443
    • Pathirathna, S.1    Brimelow, B.C.2    Jagodic, M.M.3
  • 32
    • 0035068825 scopus 로고    scopus 로고
    • Acute phenobarbital administration induces hyperalgesia: Pharmacological evidence for the involvement of supraspinal GABA-A receptors
    • Yokoro CM, Pesquero SM, Turchetti-Maia RM, Francischi JN, Tatsuo MA. Acute phenobarbital administration induces hyperalgesia: Pharmacological evidence for the involvement of supraspinal GABA-A receptors. Braz J Med Biol Res 2001, 34(3):397-405.
    • (2001) Braz J Med Biol Res , vol.34 , Issue.3 , pp. 397-405
    • Yokoro, C.M.1    Pesquero, S.M.2    Turchetti-Maia, R.M.3    Francischi, J.N.4    Tatsuo, M.A.5
  • 33
    • 0037184688 scopus 로고    scopus 로고
    • The effects of sympathectomy on capsaicin-evoked fos expression of spinal dorsal horn GABAergic neurons
    • Zou X, Lin Q, Willis WD. The effects of sympathectomy on capsaicin-evoked fos expression of spinal dorsal horn GABAergic neurons. Brain Res 2002, 958(2):322-9.
    • (2002) Brain Res , vol.958 , Issue.2 , pp. 322-329
    • Zou, X.1    Lin, Q.2    Willis, W.D.3
  • 34
    • 33846158169 scopus 로고    scopus 로고
    • The role of GABA in the mediation and perception of pain
    • Enna SJ, McCarson KE. The role of GABA in the mediation and perception of pain. Adv Pharmacol 2006, 54:1-27.
    • (2006) Adv Pharmacol , vol.54 , pp. 1-27
    • Enna, S.J.1    McCarson, K.E.2
  • 35
    • 0025007290 scopus 로고
    • Evidence that 5 α-pregnan-3 α-ol-20-one is the metabolite responsible for progesterone anesthesia
    • Mok WM, Krieger NR. Evidence that 5 α-pregnan-3 α-ol-20-one is the metabolite responsible for progesterone anesthesia. Brain Res 1990, 533(1):42-5.
    • (1990) Brain Res , vol.533 , Issue.1 , pp. 42-45
    • Mok, W.M.1    Krieger, N.R.2
  • 36
    • 5644232982 scopus 로고    scopus 로고
    • Mechanism underlying inhibition of the capsaicin receptor-mediated current by pregnenolone sulfate in rat dorsal root ganglion neurons
    • Chen SC, Wu FS. Mechanism underlying inhibition of the capsaicin receptor-mediated current by pregnenolone sulfate in rat dorsal root ganglion neurons. Brain Res 2004, 1027(1-2):196-200.
    • (2004) Brain Res , vol.1027 , Issue.1-2 , pp. 196-200
    • Chen, S.C.1    Wu, F.S.2
  • 37
    • 33748414175 scopus 로고    scopus 로고
    • Intradermal pregnenolone sulfate attenuates capsaicin-induced nociception in rats
    • Chen SC, Liu BC, Chen CW, Wu FS. Intradermal pregnenolone sulfate attenuates capsaicin-induced nociception in rats. Biochem Biophys Res Commun 2006, 349(2):626-33.
    • (2006) Biochem Biophys Res Commun , vol.349 , Issue.2 , pp. 626-633
    • Chen, S.C.1    Liu, B.C.2    Chen, C.W.3    Wu, F.S.4
  • 38
    • 33751522303 scopus 로고    scopus 로고
    • Effects of chronic osteoarthritis pain on neuroendocrine function in men
    • Khoromi S, Muniyappa R, Nackers L. Effects of chronic osteoarthritis pain on neuroendocrine function in men. J Clin Endocrinol Metab 2006, 91(11):4313-8.
    • (2006) J Clin Endocrinol Metab , vol.91 , Issue.11 , pp. 4313-4318
    • Khoromi, S.1    Muniyappa, R.2    Nackers, L.3
  • 39
    • 0142059031 scopus 로고    scopus 로고
    • Musculo-skeletal pain, psychological distress, and hormones during the menopausal transition
    • Finset A, Overlie I, Holte A. Musculo-skeletal pain, psychological distress, and hormones during the menopausal transition. Psychoneuroendocrinology 2004, 29(1):49-64.
    • (2004) Psychoneuroendocrinology , vol.29 , Issue.1 , pp. 49-64
    • Finset, A.1    Overlie, I.2    Holte, A.3
  • 40
    • 22244441097 scopus 로고    scopus 로고
    • A randomized controlled trial of dehydroepiandrosterone in postmenopausal women with fibromyalgia
    • Finckh A, Berner IC, Aubry-Rozier B, So AK. A randomized controlled trial of dehydroepiandrosterone in postmenopausal women with fibromyalgia. J Rheumatol 2005, 32(7):1336-40.
    • (2005) J Rheumatol , vol.32 , Issue.7 , pp. 1336-1340
    • Finckh, A.1    Berner, I.C.2    Aubry-Rozier, B.3    So, A.K.4
  • 41
    • 4644246248 scopus 로고    scopus 로고
    • Long-term low-dose dehydroepiandrosterone replacement therapy in aging males with partial androgen deficiency
    • Genazzani AR, Inglese S, Lombardi I. Long-term low-dose dehydroepiandrosterone replacement therapy in aging males with partial androgen deficiency. Aging Male 2004, 7(2):133-43.
    • (2004) Aging Male , vol.7 , Issue.2 , pp. 133-143
    • Genazzani, A.R.1    Inglese, S.2    Lombardi, I.3
  • 42
    • 34547522672 scopus 로고    scopus 로고
    • The relationship of allopregnanolone immunoreactivity and HPA-axis measures to experimental pain sensitivity: Evidence for ethnic differences
    • Mechlin B, Morrow AL, Maixner W, Girdler SS. The relationship of allopregnanolone immunoreactivity and HPA-axis measures to experimental pain sensitivity: Evidence for ethnic differences. Pain 2007, 131(1-2):142-52.
    • (2007) Pain , vol.131 , Issue.1-2 , pp. 142-152
    • Mechlin, B.1    Morrow, A.L.2    Maixner, W.3    Girdler, S.S.4
  • 44
    • 0029862925 scopus 로고    scopus 로고
    • Preemptive analgesic effects of steroid anesthesia with αxalone in the rat formalin test. Evidence for differential GABA(A) receptor modulation in persistent nociception
    • Gilron I, Coderre TJ. Preemptive analgesic effects of steroid anesthesia with αxalone in the rat formalin test. Evidence for differential GABA(A) receptor modulation in persistent nociception. Anesthesiology 1996, 84(3):572-9.
    • (1996) Anesthesiology , vol.84 , Issue.3 , pp. 572-579
    • Gilron, I.1    Coderre, T.J.2
  • 45
    • 0035065192 scopus 로고    scopus 로고
    • Antinociceptive properties of neurosteroids IV: Pilot study demonstrating the analgesic effects of αdolone administered orally to humans
    • Goodchild CS, Robinson A, Nadeson R. Antinociceptive properties of neurosteroids IV: Pilot study demonstrating the analgesic effects of αdolone administered orally to humans. Br J Anaesth 2001, 86(4):528-34.
    • (2001) Br J Anaesth , vol.86 , Issue.4 , pp. 528-534
    • Goodchild, C.S.1    Robinson, A.2    Nadeson, R.3
  • 46
    • 0035032016 scopus 로고    scopus 로고
    • Antinociceptive properties of neurosteroids III: Experiments with αdolone given intravenously, intraperitoneally, and intragastrically
    • Nadeson R, Goodchild CS. Antinociceptive properties of neurosteroids III: Experiments with αdolone given intravenously, intraperitoneally, and intragastrically. Br J Anaesth 2001, 86(5):704-8.
    • (2001) Br J Anaesth , vol.86 , Issue.5 , pp. 704-708
    • Nadeson, R.1    Goodchild, C.S.2
  • 47
    • 0041828387 scopus 로고    scopus 로고
    • Antinociceptive properties of neurosteroids: A comparison of αdolone and αxalone in potentiation of opioid antinociception
    • Winter L, Nadeson R, Tucker AP, Goodchild CS. Antinociceptive properties of neurosteroids: A comparison of αdolone and αxalone in potentiation of opioid antinociception. Anesth Analg 2003, 97(3):798-805.
    • (2003) Anesth Analg , vol.97 , Issue.3 , pp. 798-805
    • Winter, L.1    Nadeson, R.2    Tucker, A.P.3    Goodchild, C.S.4
  • 48
    • 0035311361 scopus 로고    scopus 로고
    • A comparison of symptom checklist 90-revised profiles from patients with chronic pain from whiplash and patients with other musculoskeletal injuries
    • Peebles JE, McWilliams LA, MacLennan R. A comparison of symptom checklist 90-revised profiles from patients with chronic pain from whiplash and patients with other musculoskeletal injuries. Spine 2001, 26(7):766-70.
    • (2001) Spine , vol.26 , Issue.7 , pp. 766-770
    • Peebles, J.E.1    McWilliams, L.A.2    MacLennan, R.3
  • 49
    • 33744496282 scopus 로고    scopus 로고
    • Neuroactive steroids, negative affect, and nicotine dependence severity in male smokers
    • Marx CE, Trost WT, Shampine L. Neuroactive steroids, negative affect, and nicotine dependence severity in male smokers. Psychopharmacology 2006, 186(3):462-72.
    • (2006) Psychopharmacology , vol.186 , Issue.3 , pp. 462-472
    • Marx, C.E.1    Trost, W.T.2    Shampine, L.3
  • 50
    • 33751539032 scopus 로고    scopus 로고
    • The neurosteroid allopregnanolone is reduced in prefrontal cortex in Alzheimer's disease
    • Marx CE, Trost WT, Shampine LJ. The neurosteroid allopregnanolone is reduced in prefrontal cortex in Alzheimer's disease. Biol Psychiatry 2006, 60(12):1287-94.
    • (2006) Biol Psychiatry , vol.60 , Issue.12 , pp. 1287-1294
    • Marx, C.E.1    Trost, W.T.2    Shampine, L.J.3
  • 52
    • 0142209421 scopus 로고    scopus 로고
    • Traumatic brain injury in U.S. Army paratroopers: Prevalence and character
    • Ivins BJ, Schwab KA, Warden D. Traumatic brain injury in U.S. Army paratroopers: Prevalence and character. J Trauma 2003, 55(4):617-21.
    • (2003) J Trauma , vol.55 , Issue.4 , pp. 617-621
    • Ivins, B.J.1    Schwab, K.A.2    Warden, D.3
  • 53
    • 33846471098 scopus 로고    scopus 로고
    • The alcohol use disorders identification test: An update of research findings
    • Reinert DF, Allen JP. The alcohol use disorders identification test: An update of research findings. Alcohol Clin Exp Res 2007, 31(2):185-99.
    • (2007) Alcohol Clin Exp Res , vol.31 , Issue.2 , pp. 185-199
    • Reinert, D.F.1    Allen, J.P.2
  • 54
    • 15144344290 scopus 로고    scopus 로고
    • Circulating levels of allopregnanolone in humans: Gender, age, and endocrine influences
    • Genazzani AR, Petraglia F, Bernardi F. Circulating levels of allopregnanolone in humans: Gender, age, and endocrine influences. J Clin Endocrinol Metab 1998, 83(6):2099-103.
    • (1998) J Clin Endocrinol Metab , vol.83 , Issue.6 , pp. 2099-2103
    • Genazzani, A.R.1    Petraglia, F.2    Bernardi, F.3
  • 55
    • 0035336907 scopus 로고    scopus 로고
    • Allopregnanolone levels and reactivity to mental stress in premenstrual dysphoric disorder
    • Girdler SS, Straneva PA, Light KC, Pedersen CA, Morrow AL. Allopregnanolone levels and reactivity to mental stress in premenstrual dysphoric disorder. Biol Psychiatry 2001, 49(9):788-97.
    • (2001) Biol Psychiatry , vol.49 , Issue.9 , pp. 788-797
    • Girdler, S.S.1    Straneva, P.A.2    Light, K.C.3    Pedersen, C.A.4    Morrow, A.L.5
  • 56
    • 0036204519 scopus 로고    scopus 로고
    • Pulsatile secretory characteristics of allopregnanolone, a neuroactive steroid, during the menstrual cycle and in amenorrheic subjects
    • Genazzani AD, Luisi M, Malavasi B. Pulsatile secretory characteristics of allopregnanolone, a neuroactive steroid, during the menstrual cycle and in amenorrheic subjects. Eur J Endocrinol 2002, 146(3):347-56.
    • (2002) Eur J Endocrinol , vol.146 , Issue.3 , pp. 347-356
    • Genazzani, A.D.1    Luisi, M.2    Malavasi, B.3
  • 57
    • 33744497811 scopus 로고    scopus 로고
    • 3α,5α-THP: A potential plasma neurosteroid biomarker in Alzheimer's disease and perhaps non-Alzheimer's dementia
    • Smith CD, Wekstein DR, Markesbery WR, Frye CA. 3α,5α-THP: A potential plasma neurosteroid biomarker in Alzheimer's disease and perhaps non-Alzheimer's dementia. Psychopharmacology 2006, 186(3):481-5.
    • (2006) Psychopharmacology , vol.186 , Issue.3 , pp. 481-485
    • Smith, C.D.1    Wekstein, D.R.2    Markesbery, W.R.3    Frye, C.A.4
  • 58
    • 0034455530 scopus 로고    scopus 로고
    • Neurosteroid levels are increased in vivo after LPS treatment and negatively regulate LPS-induced TNF production
    • Ghezzi P, Santo ED, Sacco S. Neurosteroid levels are increased in vivo after LPS treatment and negatively regulate LPS-induced TNF production. Eur Cytokine Netw 2000, 11(3):464-9.
    • (2000) Eur Cytokine Netw , vol.11 , Issue.3 , pp. 464-469
    • Ghezzi, P.1    Santo, E.D.2    Sacco, S.3
  • 59
    • 4544282704 scopus 로고    scopus 로고
    • Progesterone and allopregnanolone reduce inflammatory cytokines after traumatic brain injury
    • He J, Evans CO, Hoffman SW, Oyesiku NM, Stein DG. Progesterone and allopregnanolone reduce inflammatory cytokines after traumatic brain injury. Exp Neurol 2004, 189(2):404-12.
    • (2004) Exp Neurol , vol.189 , Issue.2 , pp. 404-412
    • He, J.1    Evans, C.O.2    Hoffman, S.W.3    Oyesiku, N.M.4    Stein, D.G.5
  • 60
    • 11244306642 scopus 로고    scopus 로고
    • Niemann pick type C disease as a model for defects in neurosteroidogenesis
    • Mellon S, Gong W, Griffin LD. Niemann pick type C disease as a model for defects in neurosteroidogenesis. Endo Res 2004, 30(4):727-35.
    • (2004) Endo Res , vol.30 , Issue.4 , pp. 727-735
    • Mellon, S.1    Gong, W.2    Griffin, L.D.3
  • 61
    • 3142774112 scopus 로고    scopus 로고
    • Niemann-Pick type C disease involves disrupted neurosteroidogenesis and responds to allopregnanolone
    • Griffin LD, Gong W, Verot L, Mellon SH. Niemann-Pick type C disease involves disrupted neurosteroidogenesis and responds to allopregnanolone. Nat Med 2004, 10(7):704-11.
    • (2004) Nat Med , vol.10 , Issue.7 , pp. 704-711
    • Griffin, L.D.1    Gong, W.2    Verot, L.3    Mellon, S.H.4
  • 62
    • 28544432842 scopus 로고    scopus 로고
    • Allopregnanolone treatment, both as a single injection or repetitively, delays demyelination and enhances survival of Niemann-Pick C mice
    • Ahmad I, Lope-Piedrafita S, Bi X. Allopregnanolone treatment, both as a single injection or repetitively, delays demyelination and enhances survival of Niemann-Pick C mice. J Neurosci Res 2005, 82(6):811-21.
    • (2005) J Neurosci Res , vol.82 , Issue.6 , pp. 811-821
    • Ahmad, I.1    Lope-Piedrafita, S.2    Bi, X.3
  • 63
    • 0041730324 scopus 로고    scopus 로고
    • Progesterone and its metabolites increase myelin basic protein expression in organotypic slice cultures of rat cerebellum
    • Ghoumari AM, Ibanez C, El-Etr M. Progesterone and its metabolites increase myelin basic protein expression in organotypic slice cultures of rat cerebellum. J Neurochem 2003, 86(4):848-59.
    • (2003) J Neurochem , vol.86 , Issue.4 , pp. 848-859
    • Ghoumari, A.M.1    Ibanez, C.2    El-Etr, M.3
  • 64
    • 0347418151 scopus 로고    scopus 로고
    • Allopregnanolone and progesterone decrease cell death and cognitive deficits after a contusion of the rat pre-frontal cortex
    • Djebaili M, Hoffman SW, Stein DG. Allopregnanolone and progesterone decrease cell death and cognitive deficits after a contusion of the rat pre-frontal cortex. Neuroscience 2004, 123(2):349-59.
    • (2004) Neuroscience , vol.123 , Issue.2 , pp. 349-359
    • Djebaili, M.1    Hoffman, S.W.2    Stein, D.G.3
  • 65
    • 12544255204 scopus 로고    scopus 로고
    • The neurosteroids progesterone and allopregnanolone reduce cell death, gliosis, and functional deficits after traumatic brain injury in rats
    • Djebaili M, Guo Q, Pettus EH, Hoffman SW, Stein DG. The neurosteroids progesterone and allopregnanolone reduce cell death, gliosis, and functional deficits after traumatic brain injury in rats. J Neurotrauma 2005, 22(1):106-18.
    • (2005) J Neurotrauma , vol.22 , Issue.1 , pp. 106-118
    • Djebaili, M.1    Guo, Q.2    Pettus, E.H.3    Hoffman, S.W.4    Stein, D.G.5
  • 66
    • 0027505544 scopus 로고
    • Traumatic brain injury and chronic pain: Differential types and rates by head injury severity
    • Uomoto JM, Esselman PC. Traumatic brain injury and chronic pain: Differential types and rates by head injury severity. Arch Phys Med Rehabil 1993, 74(1):61-4.
    • (1993) Arch Phys Med Rehabil , vol.74 , Issue.1 , pp. 61-64
    • Uomoto, J.M.1    Esselman, P.C.2
  • 67
    • 0029787316 scopus 로고    scopus 로고
    • Incidence of chronic pain following traumatic brain injury
    • Lahz S, Bryant RA. Incidence of chronic pain following traumatic brain injury. Arch Phys Med Rehabil 1996, 77(9):889-91.
    • (1996) Arch Phys Med Rehabil , vol.77 , Issue.9 , pp. 889-891
    • Lahz, S.1    Bryant, R.A.2
  • 68
    • 0033388437 scopus 로고    scopus 로고
    • Interaction of posttraumatic stress disorder and chronic pain following traumatic brain injury
    • Bryant RA, Marosszeky JE, Crooks J, Baguley IJ, Gurka JA. Interaction of posttraumatic stress disorder and chronic pain following traumatic brain injury. J Head Trauma Rehabil 1999, 14(6):588-94.
    • (1999) J Head Trauma Rehabil , vol.14 , Issue.6 , pp. 588-594
    • Bryant, R.A.1    Marosszeky, J.E.2    Crooks, J.3    Baguley, I.J.4    Gurka, J.A.5
  • 69
    • 25144492663 scopus 로고    scopus 로고
    • Headache after moderate and severe traumatic brain injury: A longitudinal analysis
    • Walker WC, Seel RT, Curtiss G, Warden DL. Headache after moderate and severe traumatic brain injury: A longitudinal analysis. Arch Phys Med Rehabil 2005, 86(9):1793-800.
    • (2005) Arch Phys Med Rehabil , vol.86 , Issue.9 , pp. 1793-1800
    • Walker, W.C.1    Seel, R.T.2    Curtiss, G.3    Warden, D.L.4
  • 70
    • 50249159949 scopus 로고    scopus 로고
    • Integrative outpatient treatment for returning service members
    • Batten SV, Pollack SJ. Integrative outpatient treatment for returning service members. J Clin Psychol 2008, 64(8):928-39.
    • (2008) J Clin Psychol , vol.64 , Issue.8 , pp. 928-939
    • Batten, S.V.1    Pollack, S.J.2
  • 71
    • 77957233350 scopus 로고    scopus 로고
    • VHA Office of Public Health and Environmental Hazards. Reports on Returning Combat Veterans
    • Washington, DC, Veterans Health Administration
    • VHA Office of Public Health and Environmental Hazards. Reports on Returning Combat Veterans. 2008, Washington, DC, Veterans Health Administration
    • (2008)


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.