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Volumn 34, Issue 5, 2010, Pages 634-638

Distribution of TYMS, MTHFR, p53 and MDR1 gene polymorphisms in patients with breast cancer treated with neoadjuvant chemotherapy

Author keywords

Adverse reaction; Breast cancer; MTHFR; Neoadjuvant chemotherapy; P53; Polymorphism; Toxicity

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); CYCLOPHOSPHAMIDE; DOCETAXEL; EPIRUBICIN; FLUOROURACIL; METHOTREXATE; MULTIDRUG RESISTANCE PROTEIN 1; PACLITAXEL; PROTEIN P53; THYMIDYLATE SYNTHASE;

EID: 77957240834     PISSN: 18777821     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canep.2010.06.013     Document Type: Article
Times cited : (30)

References (44)
  • 1
    • 33646568784 scopus 로고    scopus 로고
    • Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world
    • Kamangar F., Dores G.M., Anderson W.F. Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world. J Clin Oncol 2006, 24:2137-2150.
    • (2006) J Clin Oncol , vol.24 , pp. 2137-2150
    • Kamangar, F.1    Dores, G.M.2    Anderson, W.F.3
  • 3
    • 17444454498 scopus 로고    scopus 로고
    • Effect of preoperative chemotherapy on local-regional disease in women with operable breast cancer: findings from National Surgical Adjuvant Breast and Bowel Project B-18
    • Fisher B., Brown A., Mamounas E., Wieand S., Robidoux A., Margolese R.G., et al. Effect of preoperative chemotherapy on local-regional disease in women with operable breast cancer: findings from National Surgical Adjuvant Breast and Bowel Project B-18. J Clin Oncol 1997, 15:2483-2493.
    • (1997) J Clin Oncol , vol.15 , pp. 2483-2493
    • Fisher, B.1    Brown, A.2    Mamounas, E.3    Wieand, S.4    Robidoux, A.5    Margolese, R.G.6
  • 4
    • 1442300286 scopus 로고    scopus 로고
    • Polymorphisms in genes involved in folate metabolism and colorectal neoplasia: a HuGE review
    • Sharp L., Little J. Polymorphisms in genes involved in folate metabolism and colorectal neoplasia: a HuGE review. Am J Epidemiol 2004, 159:423-443.
    • (2004) Am J Epidemiol , vol.159 , pp. 423-443
    • Sharp, L.1    Little, J.2
  • 5
    • 33745775921 scopus 로고    scopus 로고
    • Pharmacogenomics: from bedside to clinical practice
    • Marsh S., McLeod HL Pharmacogenomics: from bedside to clinical practice. Hum Mol Genet 2006, 15(Spec No. 1):R89-R93.
    • (2006) Hum Mol Genet , vol.15 , Issue.SPEC NO. 1
    • Marsh, S.1    McLeod, H.L.2
  • 6
    • 0033427561 scopus 로고    scopus 로고
    • Polymorphic tandem repeats in the thymidylate synthase gene is associated with its protein expression in human gastrointestinal cancers
    • Kawakami K., Omura K., Kanehira E., Watanabe Y. Polymorphic tandem repeats in the thymidylate synthase gene is associated with its protein expression in human gastrointestinal cancers. Anticancer Res 1999, 19:3249-3252.
    • (1999) Anticancer Res , vol.19 , pp. 3249-3252
    • Kawakami, K.1    Omura, K.2    Kanehira, E.3    Watanabe, Y.4
  • 7
    • 23244434827 scopus 로고    scopus 로고
    • Pharmacogenomics in colorectal carcinomas: future perspectives in personalized therapy
    • Russo A., Corsale S., Cammareri P., Agnese V., Cascio S., Di Fede G., et al. Pharmacogenomics in colorectal carcinomas: future perspectives in personalized therapy. J Cell Physiol 2005, 204:742-749.
    • (2005) J Cell Physiol , vol.204 , pp. 742-749
    • Russo, A.1    Corsale, S.2    Cammareri, P.3    Agnese, V.4    Cascio, S.5    Di Fede, G.6
  • 8
    • 34147111853 scopus 로고    scopus 로고
    • Impact of pharmacogenomics on clinical practice in oncology
    • Marsh S. Impact of pharmacogenomics on clinical practice in oncology. Mol Diagn Ther 2007, 11:79-82.
    • (2007) Mol Diagn Ther , vol.11 , pp. 79-82
    • Marsh, S.1
  • 9
    • 37349058652 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase (MTHFR) variants and fluorouracil-based treatments in colorectal cancer
    • Etienne-Grimaldi M.C., Francoual M., Formento J.L., Milano G. Methylenetetrahydrofolate reductase (MTHFR) variants and fluorouracil-based treatments in colorectal cancer. Pharmacogenomics 2007, 8:1561-1566.
    • (2007) Pharmacogenomics , vol.8 , pp. 1561-1566
    • Etienne-Grimaldi, M.C.1    Francoual, M.2    Formento, J.L.3    Milano, G.4
  • 10
    • 58849149494 scopus 로고    scopus 로고
    • Pharmacogenetics and pharmacogenomics of anticancer agents
    • Huang R.S., Ratain M.J. Pharmacogenetics and pharmacogenomics of anticancer agents. CA Cancer J Clin 2009, 59:42-55.
    • (2009) CA Cancer J Clin , vol.59 , pp. 42-55
    • Huang, R.S.1    Ratain, M.J.2
  • 11
    • 40549098155 scopus 로고    scopus 로고
    • Polymorphisms in the methylenetetrahydrofolate reductase gene are determinant for vascular complications after liver transplantation
    • Akoglu B., Kindl P., Weber N., Trojan J., Caspary W.F., Faust D. Polymorphisms in the methylenetetrahydrofolate reductase gene are determinant for vascular complications after liver transplantation. Eur J Clin Nutr 2008, 62:430-435.
    • (2008) Eur J Clin Nutr , vol.62 , pp. 430-435
    • Akoglu, B.1    Kindl, P.2    Weber, N.3    Trojan, J.4    Caspary, W.F.5    Faust, D.6
  • 13
    • 34547699409 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase C677T and A1298C gene variants in adult non-Hodgkin's lymphoma patients: association with toxicity and survival
    • Gemmati D., Ongaro A., Tognazzo S., Catozzi L., Federici F., Mauro E., et al. Methylenetetrahydrofolate reductase C677T and A1298C gene variants in adult non-Hodgkin's lymphoma patients: association with toxicity and survival. Haematologica 2007, 92:478-485.
    • (2007) Haematologica , vol.92 , pp. 478-485
    • Gemmati, D.1    Ongaro, A.2    Tognazzo, S.3    Catozzi, L.4    Federici, F.5    Mauro, E.6
  • 14
    • 0037221767 scopus 로고    scopus 로고
    • TP53 and breast cancer
    • Borresen-Dale A.L. TP53 and breast cancer. Hum Mutat 2003, 21:292-300.
    • (2003) Hum Mutat , vol.21 , pp. 292-300
    • Borresen-Dale, A.L.1
  • 15
    • 0033744152 scopus 로고    scopus 로고
    • P53 codon 72 polymorphism as a risk factor in the development of breast cancer
    • Papadakis E.N., Dokianakis D.N., Spandidos D.A. p53 codon 72 polymorphism as a risk factor in the development of breast cancer. Mol Cell Biol Res Commun 2000, 3:389-392.
    • (2000) Mol Cell Biol Res Commun , vol.3 , pp. 389-392
    • Papadakis, E.N.1    Dokianakis, D.N.2    Spandidos, D.A.3
  • 16
    • 0037372005 scopus 로고    scopus 로고
    • The codon 72 polymorphic variants of p53 have markedly different apoptotic potential
    • Dumont P., Leu J.I., Della Pietra A.C., George D.L., Murphy M. The codon 72 polymorphic variants of p53 have markedly different apoptotic potential. Nat Genet 2003, 33:357-365.
    • (2003) Nat Genet , vol.33 , pp. 357-365
    • Dumont, P.1    Leu, J.I.2    Della Pietra, A.C.3    George, D.L.4    Murphy, M.5
  • 17
    • 27144536311 scopus 로고    scopus 로고
    • P53 Codon 72 polymorphism predicts the pathologic response to neoadjuvant chemotherapy in patients with breast cancer
    • Xu Y., Yao L., Ouyang T., Li J., Wang T., Fan Z., et al. p53 Codon 72 polymorphism predicts the pathologic response to neoadjuvant chemotherapy in patients with breast cancer. Clin Cancer Res 2005, 11:7328-7333.
    • (2005) Clin Cancer Res , vol.11 , pp. 7328-7333
    • Xu, Y.1    Yao, L.2    Ouyang, T.3    Li, J.4    Wang, T.5    Fan, Z.6
  • 18
    • 0037362355 scopus 로고    scopus 로고
    • ATP binding cassette transporters and drug resistance in breast cancer
    • Leonessa F., Clarke R. ATP binding cassette transporters and drug resistance in breast cancer. Endocr Relat Cancer 2003, 10:43-73.
    • (2003) Endocr Relat Cancer , vol.10 , pp. 43-73
    • Leonessa, F.1    Clarke, R.2
  • 19
    • 0034724324 scopus 로고    scopus 로고
    • Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
    • Hoffmeyer S., Burk O., von Richter O., Arnold H.P., Brockmoller J., Johne A., et al. Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. Proc Natl Acad Sci U S A 2000, 97:3473-3478.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 3473-3478
    • Hoffmeyer, S.1    Burk, O.2    von Richter, O.3    Arnold, H.P.4    Brockmoller, J.5    Johne, A.6
  • 20
    • 35448992847 scopus 로고    scopus 로고
    • Silent polymorphisms speak: how they affect pharmacogenomics and the treatment of cancer
    • Sauna Z.E., Kimchi-Sarfaty C., Ambudkar S.V., Gottesman M.M. Silent polymorphisms speak: how they affect pharmacogenomics and the treatment of cancer. Cancer Res 2007, 67:9609-9612.
    • (2007) Cancer Res , vol.67 , pp. 9609-9612
    • Sauna, Z.E.1    Kimchi-Sarfaty, C.2    Ambudkar, S.V.3    Gottesman, M.M.4
  • 21
    • 34548007925 scopus 로고    scopus 로고
    • A polymorphism C3435T of the MDR-1 gene associated with smoking or high body mass index increases the risk of sporadic breast cancer in women
    • Zubor P., Lasabova Z., Hatok J., Stanclova A., Danko J. A polymorphism C3435T of the MDR-1 gene associated with smoking or high body mass index increases the risk of sporadic breast cancer in women. Oncol Rep 2007, 18:211-217.
    • (2007) Oncol Rep , vol.18 , pp. 211-217
    • Zubor, P.1    Lasabova, Z.2    Hatok, J.3    Stanclova, A.4    Danko, J.5
  • 23
    • 0033168038 scopus 로고    scopus 로고
    • The SYT-SSX1 variant of synovial sarcoma is associated with a high rate of tumor cell proliferation and poor clinical outcome
    • Nilsson G., Skytting B., Xie Y., Brodin B., Perfekt R., Mandahl N., et al. The SYT-SSX1 variant of synovial sarcoma is associated with a high rate of tumor cell proliferation and poor clinical outcome. Cancer Res 1999, 59:3180-3184.
    • (1999) Cancer Res , vol.59 , pp. 3180-3184
    • Nilsson, G.1    Skytting, B.2    Xie, Y.3    Brodin, B.4    Perfekt, R.5    Mandahl, N.6
  • 24
    • 0036274024 scopus 로고    scopus 로고
    • C-erbB-2 in breast cancer: development of a clinically useful marker
    • Hayes D.F., Thor A.D. c-erbB-2 in breast cancer: development of a clinically useful marker. Semin Oncol 2002, 29:231-245.
    • (2002) Semin Oncol , vol.29 , pp. 231-245
    • Hayes, D.F.1    Thor, A.D.2
  • 27
    • 67650739707 scopus 로고    scopus 로고
    • 249 TP53 mutation has high prevalence and is correlated with larger and poorly differentiated HCC in Brazilian patients
    • Nogueira J.A., Ono-Nita S.K., Nita M.E., de Souza M.M., do Carmo E.P., Mello E.S., et al. 249 TP53 mutation has high prevalence and is correlated with larger and poorly differentiated HCC in Brazilian patients. BMC Cancer 2009, 9:204.
    • (2009) BMC Cancer , vol.9 , pp. 204
    • Nogueira, J.A.1    Ono-Nita, S.K.2    Nita, M.E.3    de Souza, M.M.4    do Carmo, E.P.5    Mello, E.S.6
  • 28
    • 43149111567 scopus 로고    scopus 로고
    • Influence of MTHFR and RFC1 polymorphisms on toxicities during maintenance chemotherapy for childhood acute lymphoblastic leukemia or lymphoma
    • Shimasaki N., Mori T., Torii C., Sato R., Shimada H., Tanigawara Y., et al. Influence of MTHFR and RFC1 polymorphisms on toxicities during maintenance chemotherapy for childhood acute lymphoblastic leukemia or lymphoma. J Pediatr Hematol Oncol 2008, 30:347-352.
    • (2008) J Pediatr Hematol Oncol , vol.30 , pp. 347-352
    • Shimasaki, N.1    Mori, T.2    Torii, C.3    Sato, R.4    Shimada, H.5    Tanigawara, Y.6
  • 29
    • 34548798662 scopus 로고    scopus 로고
    • GSTP1 and MTHFR polymorphisms are related with toxicity in breast cancer adjuvant anthracycline-based treatment
    • Zarate R., Gonzalez-Santigo S., de la Haba J., Bandres E., Morales R., Salgado J., et al. GSTP1 and MTHFR polymorphisms are related with toxicity in breast cancer adjuvant anthracycline-based treatment. Curr Drug Metab 2007, 8:481-486.
    • (2007) Curr Drug Metab , vol.8 , pp. 481-486
    • Zarate, R.1    Gonzalez-Santigo, S.2    de la Haba, J.3    Bandres, E.4    Morales, R.5    Salgado, J.6
  • 30
    • 67749114009 scopus 로고    scopus 로고
    • Gene polymorphisms in folate metabolizing enzymes in adult acute lymphoblastic leukemia: effects on methotrexate-related toxicity and survival
    • Ongaro A., De Mattei M., Della Porta M.G., Rigolin G., Ambrosio C., Di Raimondo F., et al. Gene polymorphisms in folate metabolizing enzymes in adult acute lymphoblastic leukemia: effects on methotrexate-related toxicity and survival. Haematologica 2009, 94:1391-1398.
    • (2009) Haematologica , vol.94 , pp. 1391-1398
    • Ongaro, A.1    De Mattei, M.2    Della Porta, M.G.3    Rigolin, G.4    Ambrosio, C.5    Di Raimondo, F.6
  • 31
    • 38949175429 scopus 로고    scopus 로고
    • Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphisms and toxicity to capecitabine in advanced colorectal cancer patients
    • Sharma R., Hoskins J.M., Rivory L.P., Zucknick M., London R., Liddle C., et al. Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphisms and toxicity to capecitabine in advanced colorectal cancer patients. Clin Cancer Res 2008, 14:817-825.
    • (2008) Clin Cancer Res , vol.14 , pp. 817-825
    • Sharma, R.1    Hoskins, J.M.2    Rivory, L.P.3    Zucknick, M.4    London, R.5    Liddle, C.6
  • 32
    • 70249135219 scopus 로고    scopus 로고
    • Molecular markers of response and toxicity to FOLFOX chemotherapy in metastatic colorectal cancer
    • Chua W., Goldstein D., Lee C.K., Dhillon H., Michael M., Mitchell P., et al. Molecular markers of response and toxicity to FOLFOX chemotherapy in metastatic colorectal cancer. Br J Cancer 2009, 101:998-1004.
    • (2009) Br J Cancer , vol.101 , pp. 998-1004
    • Chua, W.1    Goldstein, D.2    Lee, C.K.3    Dhillon, H.4    Michael, M.5    Mitchell, P.6
  • 33
    • 0033998678 scopus 로고    scopus 로고
    • MTHFR gene polymorphism and severe toxicity during adjuvant treatment of early breast cancer with cyclophosphamide, methotrexate, and fluorouracil (CMF)
    • Toffoli G., Veronesi A., Boiocchi M., Crivellari D. MTHFR gene polymorphism and severe toxicity during adjuvant treatment of early breast cancer with cyclophosphamide, methotrexate, and fluorouracil (CMF). Ann Oncol 2000, 11:373-374.
    • (2000) Ann Oncol , vol.11 , pp. 373-374
    • Toffoli, G.1    Veronesi, A.2    Boiocchi, M.3    Crivellari, D.4
  • 34
    • 67349244038 scopus 로고    scopus 로고
    • Predictors of survival and toxicity in patients on adjuvant therapy with 5-fluorouracil for colorectal cancer
    • Gusella M., Frigo A.C., Bolzonella C., Marinelli R., Barile C., Bononi A., et al. Predictors of survival and toxicity in patients on adjuvant therapy with 5-fluorouracil for colorectal cancer. Br J Cancer 2009, 100:1549-1557.
    • (2009) Br J Cancer , vol.100 , pp. 1549-1557
    • Gusella, M.1    Frigo, A.C.2    Bolzonella, C.3    Marinelli, R.4    Barile, C.5    Bononi, A.6
  • 35
    • 68449090047 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase C677T and A1298C gene polymorphisms and therapy-related toxicity in children treated for acute lymphoblastic leukemia and non-Hodgkin lymphoma
    • Kantar M., Kosova B., Cetingul N., Gumus S., Toroslu E., Zafer N., et al. Methylenetetrahydrofolate reductase C677T and A1298C gene polymorphisms and therapy-related toxicity in children treated for acute lymphoblastic leukemia and non-Hodgkin lymphoma. Leuk Lymphoma 2009, 50:912-917.
    • (2009) Leuk Lymphoma , vol.50 , pp. 912-917
    • Kantar, M.1    Kosova, B.2    Cetingul, N.3    Gumus, S.4    Toroslu, E.5    Zafer, N.6
  • 36
    • 70349646312 scopus 로고    scopus 로고
    • MTHFR polymorphisms and 5-FU-based adjuvant chemotherapy in colorectal cancer
    • Afzal S., Jensen S.A., Vainer B., Vogel U., Matsen J.P., Sorensen J.B., et al. MTHFR polymorphisms and 5-FU-based adjuvant chemotherapy in colorectal cancer. Ann Oncol 2009, 20:1660-1666.
    • (2009) Ann Oncol , vol.20 , pp. 1660-1666
    • Afzal, S.1    Jensen, S.A.2    Vainer, B.3    Vogel, U.4    Matsen, J.P.5    Sorensen, J.B.6
  • 37
    • 67651229706 scopus 로고    scopus 로고
    • Role of the MTHFR polymorphisms in cancer risk modification and treatment
    • Kim Y.I. Role of the MTHFR polymorphisms in cancer risk modification and treatment. Future Oncol 2009, 5:523-542.
    • (2009) Future Oncol , vol.5 , pp. 523-542
    • Kim, Y.I.1
  • 38
    • 33749659481 scopus 로고    scopus 로고
    • Association of specific p53 polymorphisms with keratosis in individuals exposed to arsenic through drinking water in West Bengal, India
    • De Chaudhuri S., Mahata J., Das J.K., Mukherjee A., Ghosh P., Sau T.J., et al. Association of specific p53 polymorphisms with keratosis in individuals exposed to arsenic through drinking water in West Bengal, India. Mutat Res 2006, 601:102-112.
    • (2006) Mutat Res , vol.601 , pp. 102-112
    • De Chaudhuri, S.1    Mahata, J.2    Das, J.K.3    Mukherjee, A.4    Ghosh, P.5    Sau, T.J.6
  • 39
    • 0029618736 scopus 로고
    • Single-agent paclitaxel by 3-hour infusion in the treatment of non-small cell lung cancer: links between p53 and K-ras gene status and chemosensitivity
    • Rosell R., Gonzalez-Larriba J.L., Alberola V., Molina F., Monzo M., Benito D., et al. Single-agent paclitaxel by 3-hour infusion in the treatment of non-small cell lung cancer: links between p53 and K-ras gene status and chemosensitivity. Semin Oncol 1995, 22:12-18.
    • (1995) Semin Oncol , vol.22 , pp. 12-18
    • Rosell, R.1    Gonzalez-Larriba, J.L.2    Alberola, V.3    Molina, F.4    Monzo, M.5    Benito, D.6
  • 40
    • 0027285380 scopus 로고
    • P53 mutations increase resistance to ionizing radiation
    • Lee J.M., Bernstein A. p53 mutations increase resistance to ionizing radiation. Proc Natl Acad Sci U S A 1993, 90:5742-5746.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 5742-5746
    • Lee, J.M.1    Bernstein, A.2
  • 42
    • 75549089797 scopus 로고    scopus 로고
    • Genetic polymorphisms and the efficacy and toxicity of cisplatin-based chemotherapy in ovarian cancer patients
    • Khrunin A.V., Moisseev A., Gorbunova V., Limborska S. Genetic polymorphisms and the efficacy and toxicity of cisplatin-based chemotherapy in ovarian cancer patients. Pharmacogenomics J 2010, 10:54-61.
    • (2010) Pharmacogenomics J , vol.10 , pp. 54-61
    • Khrunin, A.V.1    Moisseev, A.2    Gorbunova, V.3    Limborska, S.4
  • 43
    • 59149097713 scopus 로고    scopus 로고
    • Limits to thymidylate synthase and TP53 genes as predictive determinants for fluoropyrimidine sensitivity and further evidence for RNA-based toxicity as a major influence
    • Brody J.R., Hucl T., Costantino C.L., Eshleman J.R., Gallmeier E., Zhu H., et al. Limits to thymidylate synthase and TP53 genes as predictive determinants for fluoropyrimidine sensitivity and further evidence for RNA-based toxicity as a major influence. Cancer Res 2009, 69:984-991.
    • (2009) Cancer Res , vol.69 , pp. 984-991
    • Brody, J.R.1    Hucl, T.2    Costantino, C.L.3    Eshleman, J.R.4    Gallmeier, E.5    Zhu, H.6
  • 44
    • 35648997048 scopus 로고    scopus 로고
    • Pharmacogenetic assessment of toxicity and outcome after platinum plus taxane chemotherapy in ovarian cancer: the Scottish Randomised Trial in Ovarian Cancer
    • Marsh S., Paul J., King C.R., Gifford G., McLeod H.L., Brown R. Pharmacogenetic assessment of toxicity and outcome after platinum plus taxane chemotherapy in ovarian cancer: the Scottish Randomised Trial in Ovarian Cancer. J Clin Oncol 2007, 25:4528-4535.
    • (2007) J Clin Oncol , vol.25 , pp. 4528-4535
    • Marsh, S.1    Paul, J.2    King, C.R.3    Gifford, G.4    McLeod, H.L.5    Brown, R.6


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