메뉴 건너뛰기




Volumn 62, Issue 3, 2010, Pages 227-235

The minipig as a platform for new technologies in toxicology

Author keywords

Gene manipulation; Genomics; Methods; Minipig; RETHINK; Toxicology

Indexed keywords

AGRICULTURE; ANIMAL DISEASE; ANIMAL GENETICS; ARTICLE; BIOSENSOR; COMPUTER MODEL; DOG; GENOMICS; IMMUNE SYSTEM; KNOWLEDGE BASE; MINIPIG; MONKEY; NONHUMAN; PHENOTYPE; SAFETY; SEQUENCE HOMOLOGY; TOXICOLOGY; TRANSGENIC ANIMAL; TRANSGENICS;

EID: 77957240562     PISSN: 10568719     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vascn.2010.05.007     Document Type: Article
Times cited : (67)

References (62)
  • 2
    • 0033569332 scopus 로고    scopus 로고
    • Reciprocal chromosome painting reveals detailed regions of conserved synteny between the karyotypes of the domestic dog /Canis familiaris) and human
    • Breen M., Thomas R., Binns M.M., Carter N.P., Langford C.F. Reciprocal chromosome painting reveals detailed regions of conserved synteny between the karyotypes of the domestic dog /Canis familiaris) and human. Genomics 1999, 61:145-155.
    • (1999) Genomics , vol.61 , pp. 145-155
    • Breen, M.1    Thomas, R.2    Binns, M.M.3    Carter, N.P.4    Langford, C.F.5
  • 3
    • 0024533770 scopus 로고
    • Gene transfer in swine by DNA microinjection into zygotes
    • Brem G., Springmann K. Gene transfer in swine by DNA microinjection into zygotes. Tierarztliche Praxis. Supplement 1989, 4:31-34.
    • (1989) Tierarztliche Praxis. Supplement , vol.4 , pp. 31-34
    • Brem, G.1    Springmann, K.2
  • 4
    • 36549033276 scopus 로고    scopus 로고
    • Producing primate embryonic stem cells by somatic cell nuclear transfer
    • Byrne J.A., Pedersen D.A., Clepper L.L., Nelson M., Sanger W.G., et al. Producing primate embryonic stem cells by somatic cell nuclear transfer. Nature 2007, 450:497-502.
    • (2007) Nature , vol.450 , pp. 497-502
    • Byrne, J.A.1    Pedersen, D.A.2    Clepper, L.L.3    Nelson, M.4    Sanger, W.G.5
  • 5
    • 25144438620 scopus 로고    scopus 로고
    • Xenotransplantation: An update on recent progress and future perspectives
    • Bucher P., Morel P., Bucher L.H. Xenotransplantation: An update on recent progress and future perspectives. Transplant International 2005, 18:894-901.
    • (2005) Transplant International , vol.18 , pp. 894-901
    • Bucher, P.1    Morel, P.2    Bucher, L.H.3
  • 6
    • 0035847075 scopus 로고    scopus 로고
    • Transgenic monkeys produced by retroviral gene transfer into mature oocytes
    • Chan A.W., Chong K.Y., Martinovich C., Simerly C., Schatten G. Transgenic monkeys produced by retroviral gene transfer into mature oocytes. Science 2001, 291:309-312.
    • (2001) Science , vol.291 , pp. 309-312
    • Chan, A.W.1    Chong, K.Y.2    Martinovich, C.3    Simerly, C.4    Schatten, G.5
  • 8
    • 33745062852 scopus 로고    scopus 로고
    • Health status of transgenic pigs expressing the human complement regulatory protein CD59
    • Deppenmeier S., Bock O., Mengel M., Niemann H., Kues W., et al. Health status of transgenic pigs expressing the human complement regulatory protein CD59. Xenotransplantation 2006, 13:345-356.
    • (2006) Xenotransplantation , vol.13 , pp. 345-356
    • Deppenmeier, S.1    Bock, O.2    Mengel, M.3    Niemann, H.4    Kues, W.5
  • 9
    • 77957226434 scopus 로고    scopus 로고
    • The RETHINK project, mini-pigs as models for the toxicity testing of new medicines and chemicals: an impact assessment
    • (this issue)
    • Forster R., Bode G., Ellegaard L., van der Laan J-W. The RETHINK project, mini-pigs as models for the toxicity testing of new medicines and chemicals: an impact assessment. Journal Pharmacological and Toxicological Methods 2010, 62:158-159. (this issue).
    • (2010) Journal Pharmacological and Toxicological Methods , vol.62 , pp. 158-159
    • Forster, R.1    Bode, G.2    Ellegaard, L.3    van der Laan, J.-W.4
  • 10
    • 77957226435 scopus 로고    scopus 로고
    • The RETHINK project on minipigs in the toxicity testing of new medicines and chemicals: conclusions and recommendations
    • (this issue)
    • Forster R., Bode G., Ellegaard L., van der Laan J-W. The RETHINK project on minipigs in the toxicity testing of new medicines and chemicals: conclusions and recommendations. Journal Pharmacological and Toxicological Methods 2010, 62:236-242. (this issue).
    • (2010) Journal Pharmacological and Toxicological Methods , vol.62 , pp. 236-242
    • Forster, R.1    Bode, G.2    Ellegaard, L.3    van der Laan, J.-W.4
  • 11
    • 0026319058 scopus 로고    scopus 로고
    • Identification of a mutation in porcine ryanodine receptor associated with malignant hyperthermia
    • Fujii J., Otsu K., Zorzato F., DE Leon S., Khanna V.K., O'Brian P.J., et al. Identification of a mutation in porcine ryanodine receptor associated with malignant hyperthermia. Science 1998, 253:448-451.
    • (1998) Science , vol.253 , pp. 448-451
    • Fujii, J.1    Otsu, K.2    Zorzato, F.3    DE Leon, S.4    Khanna, V.K.5    O'Brian, P.J.6
  • 12
    • 84934442861 scopus 로고    scopus 로고
    • Somatic cell nuclear transfer (SCNT) in mammals: The cytoplast and its reprogramming activities
    • Fulka J., Fulka H. Somatic cell nuclear transfer (SCNT) in mammals: The cytoplast and its reprogramming activities. Advances in Experimental Medicine and Biology 2007, 591:93-102.
    • (2007) Advances in Experimental Medicine and Biology , vol.591 , pp. 93-102
    • Fulka, J.1    Fulka, H.2
  • 13
    • 0030122590 scopus 로고    scopus 로고
    • A comparative map of the porcine and human genomes demonstrates Zoo-FISH and gene mapping-based chromosomal homologies
    • Frönicke L., Chowdhary B.P., Scherthan H., Gustavsson I. A comparative map of the porcine and human genomes demonstrates Zoo-FISH and gene mapping-based chromosomal homologies. Mammalian Genome 1996, 7:285-290.
    • (1996) Mammalian Genome , vol.7 , pp. 285-290
    • Frönicke, L.1    Chowdhary, B.P.2    Scherthan, H.3    Gustavsson, I.4
  • 15
    • 34547831828 scopus 로고    scopus 로고
    • Porcine transcriptome analysis based on 97 non-normalized cDNA libraries and assembly of 1,021,891 ESTs
    • Gorodkin J., Cirera S., Gilchrist M., Paniz F., Jørgensen C.B., Scheiby-Knudsen K., et al. Porcine transcriptome analysis based on 97 non-normalized cDNA libraries and assembly of 1,021,891 ESTs. Genome Biology 2007, 8(4):45.
    • (2007) Genome Biology , vol.8 , Issue.4 , pp. 45
    • Gorodkin, J.1    Cirera, S.2    Gilchrist, M.3    Paniz, F.4    Jørgensen, C.B.5    Scheiby-Knudsen, K.6
  • 17
    • 33751537273 scopus 로고    scopus 로고
    • Production of endothelial nitrite oxide synthase (eNOS) over-expressing piglets
    • Hao Y.H., Yong H.Y., Murphy C.N., Wax D., Samuel M., et al. Production of endothelial nitrite oxide synthase (eNOS) over-expressing piglets. Transgenic Research 2006, 15:739-750.
    • (2006) Transgenic Research , vol.15 , pp. 739-750
    • Hao, Y.H.1    Yong, H.Y.2    Murphy, C.N.3    Wax, D.4    Samuel, M.5
  • 18
    • 2642549957 scopus 로고    scopus 로고
    • Transgenic analysis of human drug-metabolising enzymes: preclinical drug development and toxicology
    • Henderson C.J., Wolf C.R. Transgenic analysis of human drug-metabolising enzymes: preclinical drug development and toxicology. Molecular Interventions 2003, 3:331-343.
    • (2003) Molecular Interventions , vol.3 , pp. 331-343
    • Henderson, C.J.1    Wolf, C.R.2
  • 20
    • 1842563105 scopus 로고    scopus 로고
    • Use of transgenic mice in carcinogenicity hazard assessment
    • Jacobson-Kram D., Sistare F.D., Jacobs A.C. Use of transgenic mice in carcinogenicity hazard assessment. Toxicologic Pathology 2004, 32(Suppl 1):49-52.
    • (2004) Toxicologic Pathology , vol.32 , Issue.SUPPL. 1 , pp. 49-52
    • Jacobson-Kram, D.1    Sistare, F.D.2    Jacobs, A.C.3
  • 21
    • 0034201574 scopus 로고    scopus 로고
    • ARPP-16 mRNA is up-regulated in the longissimus muscle of pigs possessing an elevated growth rate
    • Janzen M.A., Kuhlers D.L., Jungst S.B., Louis C.F. ARPP-16 mRNA is up-regulated in the longissimus muscle of pigs possessing an elevated growth rate. Journal of Animal Science 2000, 78(6):1475-1484.
    • (2000) Journal of Animal Science , vol.78 , Issue.6 , pp. 1475-1484
    • Janzen, M.A.1    Kuhlers, D.L.2    Jungst, S.B.3    Louis, C.F.4
  • 24
    • 22944473622 scopus 로고    scopus 로고
    • CDNA microarray analysis of the gene expression profile of swine muscle. Asian-Aust
    • Kim C.K., Chang Kyu Tae, Hong Yeon Hee, Jung Won Yong, Kwon Eun Jung, Cho Kwang Keun, et al. cDNA microarray analysis of the gene expression profile of swine muscle. Asian-Aust. Journal of Animal Science 2005, 18(No. 8):1080.
    • (2005) Journal of Animal Science , vol.18 , Issue.8 , pp. 1080
    • Kim, C.K.1    Chang, K.T.2    Hong, Y.H.3    Jung, W.Y.4    Kwon, E.J.5    Cho, K.K.6
  • 25
    • 69449096843 scopus 로고    scopus 로고
    • Hemizygous minipigs produced by random gene insertion and handmade cloning express the Alzheimer's disease-causing dominant mutation APPsw
    • Kragh P.M., Nielsen A.L., Li J., Du Y., Lin L., Schmidt M., et al. Hemizygous minipigs produced by random gene insertion and handmade cloning express the Alzheimer's disease-causing dominant mutation APPsw. Transgenic Research 2009, 18(4):545-558.
    • (2009) Transgenic Research , vol.18 , Issue.4 , pp. 545-558
    • Kragh, P.M.1    Nielsen, A.L.2    Li, J.3    Du, Y.4    Lin, L.5    Schmidt, M.6
  • 26
    • 29944439836 scopus 로고    scopus 로고
    • Altered light response of single rod photoreceptors in transgenic pigs expressing P347L or P347S rhodopsin
    • Kraft T.W., Allen D., Petters R.M., Hao Y., Peng Y.M., Wong F. Altered light response of single rod photoreceptors in transgenic pigs expressing P347L or P347S rhodopsin. Molecular Vision 2005, 11:1246-1256.
    • (2005) Molecular Vision , vol.11 , pp. 1246-1256
    • Kraft, T.W.1    Allen, D.2    Petters, R.M.3    Hao, Y.4    Peng, Y.M.5    Wong, F.6
  • 27
    • 33745083815 scopus 로고    scopus 로고
    • Epigenetic silencing and tissue independent expression of a novel tetracycline inducible system in double-transgenic pigs
    • Kues W.A., Schwinzer R., Wirth D., Verhoeyen E., Lemme E., et al. Epigenetic silencing and tissue independent expression of a novel tetracycline inducible system in double-transgenic pigs. The FASEB Journal 2006, 20:1200-1202.
    • (2006) The FASEB Journal , vol.20 , pp. 1200-1202
    • Kues, W.A.1    Schwinzer, R.2    Wirth, D.3    Verhoeyen, E.4    Lemme, E.5
  • 30
    • 34250708477 scopus 로고    scopus 로고
    • CYP1A1 induction and human risk assessment: An evolving tale of in vitro and in vivo studies
    • Ma Q., Lu A.Y. CYP1A1 induction and human risk assessment: An evolving tale of in vitro and in vivo studies. Drug Metabolism and Disposition 2007, 35:10009-10016.
    • (2007) Drug Metabolism and Disposition , vol.35 , pp. 10009-10016
    • Ma, Q.1    Lu, A.Y.2
  • 33
    • 0031260423 scopus 로고    scopus 로고
    • Two alfa(1, 2) fucosyltransferase genes on porcine chromosome 6q11 are closely linked to the blood group inhibitor (S) and Escherichia coli F18 receptor (ECF18R) loci
    • Meijerink E., Fries R., Voegeli P., Masabanda J., Wigger G., Stricker C., et al. Two alfa(1, 2) fucosyltransferase genes on porcine chromosome 6q11 are closely linked to the blood group inhibitor (S) and Escherichia coli F18 receptor (ECF18R) loci. Mammalian Genome 1997, 8:736-741.
    • (1997) Mammalian Genome , vol.8 , pp. 736-741
    • Meijerink, E.1    Fries, R.2    Voegeli, P.3    Masabanda, J.4    Wigger, G.5    Stricker, C.6
  • 35
    • 2442559277 scopus 로고    scopus 로고
    • A mixed-model approach for the analysis of cDNA microarray gene expression data from extreme-performing pigs after infection with Actinobacillus pleuropneumoniae
    • Moser R.J., Reverter A., Kerr C.A., Beh K.J., Lehnert S.A. A mixed-model approach for the analysis of cDNA microarray gene expression data from extreme-performing pigs after infection with Actinobacillus pleuropneumoniae. Journal of Animal Science 2004, 82(5):1261-1271.
    • (2004) Journal of Animal Science , vol.82 , Issue.5 , pp. 1261-1271
    • Moser, R.J.1    Reverter, A.2    Kerr, C.A.3    Beh, K.J.4    Lehnert, S.A.5
  • 36
    • 34147184456 scopus 로고    scopus 로고
    • Using genomic data to unravel the root of the placental mammal phylogeny
    • Apr
    • Murphy W.J., Pringle T.H., Crider T.A., Springer M.S., Miller W. Using genomic data to unravel the root of the placental mammal phylogeny. Genome Research 2007, Apr., 17(4):413-421.
    • (2007) Genome Research , vol.17 , Issue.4 , pp. 413-421
    • Murphy, W.J.1    Pringle, T.H.2    Crider, T.A.3    Springer, M.S.4    Miller, W.5
  • 38
    • 0000738795 scopus 로고
    • Production of normal piglets from microsurgically split morulae and blastocysts
    • Nagashima H., Katoh Y., Shibata K., Ogawa S. Production of normal piglets from microsurgically split morulae and blastocysts. Theriogenology 1988, 29:485-495.
    • (1988) Theriogenology , vol.29 , pp. 485-495
    • Nagashima, H.1    Katoh, Y.2    Shibata, K.3    Ogawa, S.4
  • 39
    • 0035874969 scopus 로고    scopus 로고
    • Rat-mouse and rat-human comparison maps based on gene homology and high-resolution Zoo-FISH
    • Nilsson S., Helou K., Walentinsson A., Szpirer, Nerman O., Ståhl Rat-mouse and rat-human comparison maps based on gene homology and high-resolution Zoo-FISH. Genomics 2001, 74:287-298.
    • (2001) Genomics , vol.74 , pp. 287-298
    • Nilsson, S.1    Helou, K.2    Walentinsson, A.3    Szpirer4    Nerman, O.5    Ståhl6
  • 40
    • 33644872392 scopus 로고    scopus 로고
    • Molecular genetics: DNA analysis of a putative dog clone
    • Parker H.G., Kruglyak L., Ostrander E.S. Molecular genetics: DNA analysis of a putative dog clone. Nature 2006, 440:E1-E2.
    • (2006) Nature , vol.440
    • Parker, H.G.1    Kruglyak, L.2    Ostrander, E.S.3
  • 43
    • 66449106662 scopus 로고    scopus 로고
    • Generation of transgenic non-human primates with germline transmission
    • Sasaki E., Suemizu H., Shimada A., Hanazawa K., Oiwa R., Kamioka M., et al. Generation of transgenic non-human primates with germline transmission. Nature 2009, 28(459(7246)):523-527.
    • (2009) Nature , vol.28 , Issue.459-7246 , pp. 523-527
    • Sasaki, E.1    Suemizu, H.2    Shimada, A.3    Hanazawa, K.4    Oiwa, R.5    Kamioka, M.6
  • 44
    • 4344611542 scopus 로고    scopus 로고
    • Strategies for the production of genetically identical monkeys by embryo splitting
    • Schramm R.D., Paprocki A.M. Strategies for the production of genetically identical monkeys by embryo splitting. Reproductive Biology and Endocrinology 2004, 2:38.
    • (2004) Reproductive Biology and Endocrinology , vol.2 , pp. 38
    • Schramm, R.D.1    Paprocki, A.M.2
  • 46
    • 9944234198 scopus 로고    scopus 로고
    • Embryogenesis and blastocyst development after somatic cell nuclear transfer in nonhuman primates: Overcoming defects caused by meiotic spindle extraction
    • Simerly C., Navara C., Hyun S.H., Lee B.C., Kang S.K., Campuano S., et al. Embryogenesis and blastocyst development after somatic cell nuclear transfer in nonhuman primates: Overcoming defects caused by meiotic spindle extraction. Developmental Biology 2004, 237-252.
    • (2004) Developmental Biology , pp. 237-252
    • Simerly, C.1    Navara, C.2    Hyun, S.H.3    Lee, B.C.4    Kang, S.K.5    Campuano, S.6
  • 47
    • 0037417891 scopus 로고    scopus 로고
    • Placental mammal diversification and the Cretaceous-Tertiary boundary
    • Springer M.S., Murphy W.J., Eizirik E., O'Brien S.J. Placental mammal diversification and the Cretaceous-Tertiary boundary. PNAS 2003, 100:1056-1061.
    • (2003) PNAS , vol.100 , pp. 1056-1061
    • Springer, M.S.1    Murphy, W.J.2    Eizirik, E.3    O'Brien, S.J.4
  • 48
    • 33846167435 scopus 로고    scopus 로고
    • Dolly for dinner? Assessing commercial and regulatory trends in cloned livestock
    • Suk J., Bruce A., Gertz R., Warkup C., Whitelaw C.B., Braun A., et al. Dolly for dinner? Assessing commercial and regulatory trends in cloned livestock. Natural Biotechnology 2007, 25:47-53.
    • (2007) Natural Biotechnology , vol.25 , pp. 47-53
    • Suk, J.1    Bruce, A.2    Gertz, R.3    Warkup, C.4    Whitelaw, C.B.5    Braun, A.6
  • 49
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • Takahashi K., Tanabe K., Ohnuki M., Nariat M., Ischisaka T., Tomoda K., et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007, 131:1-12.
    • (2007) Cell , vol.131 , pp. 1-12
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3    Nariat, M.4    Ischisaka, T.5    Tomoda, K.6
  • 51
    • 33846641694 scopus 로고    scopus 로고
    • Somatic cell nuclear transfer in pigs: Recent achievements and future possibilities
    • Vajta G., Zhang Y., Machaty Z.N. Somatic cell nuclear transfer in pigs: Recent achievements and future possibilities. Reproduction, Fertility, and Development 2007, 19:402-423.
    • (2007) Reproduction, Fertility, and Development , vol.19 , pp. 402-423
    • Vajta, G.1    Zhang, Y.2    Machaty, Z.N.3
  • 52
    • 0242363235 scopus 로고    scopus 로고
    • A regulatory mutation in IGF2 causes a major QTL effect on muscle growth in the pig
    • Van Laere A.S., Nguyen M., Braunschweig M., Nezer C., Collette C., Moreau L., et al. A regulatory mutation in IGF2 causes a major QTL effect on muscle growth in the pig. Nature 2003, 425:832-836.
    • (2003) Nature , vol.425 , pp. 832-836
    • Van Laere, A.S.1    Nguyen, M.2    Braunschweig, M.3    Nezer, C.4    Collette, C.5    Moreau, L.6
  • 54
    • 0033178095 scopus 로고    scopus 로고
    • Sperm-mediated gene transfer: Advances in sperm cell research and applications
    • Wall R.J. Sperm-mediated gene transfer: Advances in sperm cell research and applications. Transgenic Research 1999, 8:313-315.
    • (1999) Transgenic Research , vol.8 , pp. 313-315
    • Wall, R.J.1
  • 57
    • 1642291044 scopus 로고    scopus 로고
    • Transgenic livestock made easy
    • Whitelaw C.B. Transgenic livestock made easy. Trends Biotechnology 2004, 22:157-159.
    • (2004) Trends Biotechnology , vol.22 , pp. 157-159
    • Whitelaw, C.B.1
  • 58
  • 59
    • 21044444140 scopus 로고    scopus 로고
    • Transcriptional profiling of pig embryogenesis by using a 15-K member unigene set specific for pig reproductive tissues and embryos
    • Whitworth K.M., Agca C., Kim J.G., Patel R.V., Springer G.K., Bivens N.J., et al. Transcriptional profiling of pig embryogenesis by using a 15-K member unigene set specific for pig reproductive tissues and embryos. Biology of Reproduction 2005, 72(6):1437-1451.
    • (2005) Biology of Reproduction , vol.72 , Issue.6 , pp. 1437-1451
    • Whitworth, K.M.1    Agca, C.2    Kim, J.G.3    Patel, R.V.4    Springer, G.K.5    Bivens, N.J.6
  • 62
    • 33645455600 scopus 로고    scopus 로고
    • Production of a transgenic piglet by a sperm injection technique in which no chemical or physical treatments were used for oocyte or sperm
    • Yong H.Y., Hao Y., Lai L., Li R., Murphy C.N., Rieke A., et al. Production of a transgenic piglet by a sperm injection technique in which no chemical or physical treatments were used for oocyte or sperm. Molecular Reproduction and Development 2006, 73:595-599.
    • (2006) Molecular Reproduction and Development , vol.73 , pp. 595-599
    • Yong, H.Y.1    Hao, Y.2    Lai, L.3    Li, R.4    Murphy, C.N.5    Rieke, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.