Molecular Insight into the Conformational Dynamics of the Elongin BC Complex and Its Interaction with HIV-1 Vif

Journal of Molecular Biology

Volumn 402, Issue 5, 2010, Pages 892-904

  Marcsisin, Sean R ^a   Engen, John R ^a  

^a NORTHEASTERN UNIVERSITY   (United States)

Author keywords

APOBEC3; E3 ubiquitin ligase; Hydrogen exchange mass spectrometry; Protein conformation; Viral SOCS box

Indexed keywords

BINDING PROTEIN; CYTIDINE DEAMINASE; DEUTERIUM; ELONGATION BC COMPLEX; HETERODIMER; PROTEASOME; PROTEIN APOBEC3; RECOMBINANT PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG; VIF PROTEIN; ELONGIN; HYDROGEN; PROTEIN BINDING; TRANSCRIPTION FACTOR; VIF PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 1;

ARTICLE; CONFORMATIONAL TRANSITION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; IN VITRO STUDY; MASS SPECTROMETRY; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN FAMILY; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; UBIQUITINATION; VIRUS IMMUNITY; AMINO ACID SEQUENCE; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; MOLECULAR GENETICS; PROTEIN ANALYSIS; PROTEIN QUATERNARY STRUCTURE;

HUMAN IMMUNODEFICIENCY VIRUS 1;

AMINO ACID SEQUENCE; HUMANS; HYDROGEN; MASS SPECTROMETRY; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN INTERACTION MAPPING; PROTEIN STRUCTURE, QUATERNARY; TRANSCRIPTION FACTORS; VIF GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS;

EID: 77957235518     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2010.08.026     Document Type: Article

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