Matrix metalloproteinase (MMP-9 and MMP-2) gene polymorphisms influence allograft survival in renal transplant recipients

Nephrology Dialysis Transplantation

Volumn 25, Issue 10, 2010, Pages 3393-3401

  Singh, Ranjana ^a   Srivastava, Priyanka ^a   Srivastava, Aneesh ^a   Mittal, Rama Devi ^a  

^a SANJAY GANDHI POSTGRADUATE INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

allograft rejection; MMP 2; MMP 9; PCR RFLP; renal transplantation

Indexed keywords

CREATININE; CYCLOSPORIN A; GELATINASE A; GELATINASE B; GENOMIC DNA; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; TACROLIMUS;

ADULT; ARTICLE; BLOOD SAMPLING; CHRONIC GLOMERULONEPHRITIS; CLINICAL ASSESSMENT; CREATININE BLOOD LEVEL; DIABETIC NEPHROPATHY; DNA EXTRACTION; DRUG BLOOD LEVEL; FEMALE; GENE FREQUENCY; GENETIC POLYMORPHISM; GENOTYPE; GRAFT RECIPIENT; GRAFT REJECTION; GRAFT SURVIVAL; HAPLOTYPE; HETEROZYGOTE; HLA MATCHING; HUMAN; HYPERTENSION; IMMUNOSUPPRESSIVE TREATMENT; INDIA; INTERSTITIAL NEPHRITIS; KIDNEY GRAFT; MAJOR CLINICAL STUDY; MALE; METHODOLOGY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGNOSIS; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK REDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; TREATMENT DURATION;

ADOLESCENT; ADULT; AGED; CHILD; FEMALE; GENE FREQUENCY; GRAFT REJECTION; GRAFT SURVIVAL; HUMANS; KIDNEY TRANSPLANTATION; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; TRANSPLANTATION, HOMOLOGOUS;

EID: 77957226350     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfq174     Document Type: Article

References (25)

1. Norman JT, Lewis MP. Matrix metalloproteinases (MMPs) in renal fibrosis. Kidney Int Suppl 1996; 54: S61-S63
2. Sternlicht MD, Werb Z. How matrix metalloproteinases regulate cell behavior. Annu Rev Cell Dev Biol 2001; 17: 463-516
3. McCawley LJ, Matrisian LM. Matrix metalloproteinases: they're not just for matrix anymore! Curr Opin Cell Biol 2001; 13: 534-540
4. Garton KJ, Gough PJ, Raines EW. Emerging roles for ectodomain shedding in the regulation of inflammatory responses. J Leukoc Biol 2006; 79: 1105-1116
5. Lenz O, Elliot SJ, Stetler-Stevenson WG. Matrix metalloproteinases in renal development and disease. J Am Soc Nephrol 2000; 11: 574-581
6. Inkinen KA, Soots AP, Krogerus LA et al. Fibrosis and matrix me-talloproteinases in rat renal allografts. Transpl Int 2005; 18: 506-512
7. Johnson TS, Haylor JL, Thomas GL et al. Matrix metalloproteinases and their inhibitions in experimental renal scarring. Exp Nephrol 2002; 10: 182-195
8. Hu Z, Huo X, Lu D et al. Functional polymorphisms of matrix me-talloproteinase-9 are associated with risk of occurrence and metastasis of lung cancer. Clin Cancer Res 2005; 11: 5433-5439
9. Wu J, Zhang L, Luo H et al. Association of matrix metalloprotei-nases-9 gene polymorphisms with genetic susceptibility to esophage-al squamous cell carcinoma. DNA Cell Biol 2008; 27: 553-557
10. Li Y, Sun DL, Duan YN et al. Association of functional polymorphisms in MMPs genes with gastric cardia adenocarcinoma and esoph-ageal squamous cell carcinoma in high incidence region of North China. Mol Biol Rep 2010; 37: 197-205
11. Yamani MH, Starling RC, Young JB et al. Acute vascular rejection is associated with up-regulation of vitronectin receptor (avb3), increased expression of tissue factor, and activation of the extracellular matrix metalloproteinase induction system. J Heart Lung Transplant 2002; 21: 983-989
12. Berthier CC, Lods N, Joosten SA et al. Differential regulation of met-zincins in experimental chronic renal allograft rejection: Potential markers and novel therapeutic targets. Kidney Int 2006; 69: 358-368
13. Racusen LC, Solez K, Colvin RB et al. The Banff 97 working classification of renal allograft pathology. Kidney Int 1999; 55: 713-723
14. Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1988; 16: 1215-1215
15. Shibata N, Ohnuma T, Higashi S et al. Genetic association between matrix metalloproteinase MMP-9 and MMP-3 polymorphisms and Japanese sporadic Alzheimer's disease. Neurobiol Aging 2005; 26: 1011-1014
16. Falk V, Soccal PM, Grunenfelder J, Hoyt G, Walther T, Robbins RC. Regulation of matrix metalloproteinases and effect of MMP-inhibition in heart transplant related reperfusion injury. Eur J Cardiothorac Surg 2002; 22: 53-58
17. Campbell LG, Ramachandran S, Liu W et al. Different roles for matrix metalloproteinase-2 and matrix metalloproteinase-9 in the pathogenesis of cardiac allograft rejection. Am J Transplant 2005; 5: 517-528
18. Suzuki J, Isobe M, Kawauchi M et al. Altered expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in acutely rejected myocardium and coronary arteriosclerosis in cardiac allografts of nonhuman primates. TransplInt 2000; 13: 106-113
19. Wen H, Zhang L, Li J et al. Expression of matrix metalloproteinase-2,-9 in human esophageal cancer tissue. JZhengzhou Univ (Med Sci) 2005; 40: 497-499
20. O'Farrell TJ, Pourmotabbed T. Identification of structural elements important for matrix metalloproteinase type V collagenolytic activity as revealed by chimeric enzymes. Role of fibronectin-like domain and active site of gelatinase B. J Biol Chem 2000; 275: 27964-27972
21. Murphy G, Knauper V Relating matrix metalloproteinase structure to function: why the "hemopexin" domain? Matrix Biol 1997; 15: 511-518
22. Jin G, Miao R, Hu Z et al. Putative functional polymorphisms of MMP9 predict survival of NSCLC in a Chinese population. Int J Cancer 2009;124: 2172-2178
23. Price SJ, Greaves DR, Watkins H. Identification of novel, functional genetic variants in the human matrix metalloproteinase-2 gene: role of Sp1 in allele-specific transcriptional regulation. J Biol Chem 2000; 276: 7549-7558
24. Berthier C, Marti HP. Metzincins, including matrix metalloproteinases and meprin, in kidney transplantation. Swiss Med Wkly 2006; 136: 789-794
25. Kirimlioglu H, Kirimlioglu V, Yilmaz S. Expression of matrix metalloproteinases 2 and 9 in donor liver, cirrhotic liver, and acute rejection after human liver transplantation. Transplant Proc 2008; 40: 3574-3577