Acute vascular rejection is associated with up-regulation of vitronectin receptor (αvβ3), increased expression of tissue factor, and activation of the extracellular matrix metalloproteinase induction system

Journal of Heart and Lung Transplantation

Volumn 21, Issue 9, 2002, Pages 983-989

  Yamani, Mohamad H ^a   Starling, Randall C ^a   Young, James B ^a   Cook, Daniel ^a   Yu, Yang ^a   Vince, D Geoffrey ^a   McCarthy, Patrick ^a   Ratliff, Norman B ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MATRIX METALLOPROTEINASE; THROMBOPLASTIN; VITRONECTIN RECEPTOR;

ACUTE DISEASE; ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE COURSE; EXTRACELLULAR MATRIX; FEMALE; GRAFT REJECTION; HEART MUSCLE BIOPSY; HEMODYNAMICS; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; ISCHEMIA; LETHALITY; MALE; MORTALITY; NECROSIS; PLASMAPHERESIS; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; TIME; UPREGULATION;

ACUTE DISEASE; ADULT; ANTIGENS, CD; ANTIGENS, CD147; ANTIGENS, NEOPLASM; ENDOTHELIUM, VASCULAR; FEMALE; GRAFT REJECTION; HEART TRANSPLANTATION; HUMANS; MALE; MEMBRANE GLYCOPROTEINS; MYOCARDIUM; NECROSIS; RECEPTORS, VITRONECTIN; THROMBOPLASTIN; UP-REGULATION;

EID: 0036754489     PISSN: 10532498     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1053-2498(02)00408-4     Document Type: Article

References (27)

1. Caple J.F., McMahon J.T., Myles J.L., et al. Acute vascular (humoral) rejection in non-OKT3 treated cardiac transplants. Cardiovasc Pathol. 4:1995;13-18.
2. Hammond E.H., Yowell R.L., Nunoda S., et al. Vascular (humoral) rejection in heart transplantation pathologic observations and clinical implications . J Heart Transplant. 8:1989;430-443.
3. Miller L.W., Wesp A., Jennison S.H., et al. Vascular rejection in heart transplant recipients. J Heart Lung Transplant. 12:(2):1993;147-152.
4. Olsen S.L., Wagoner L.E., Hammond E.H., et al. Vascular rejection in heart transplantation clinical correlation, treatment options, and future considerations . J Heart Lung Transplant. 12:1993;S135-S142.
5. Ratliff N.B., McMahon J.T. Activation of intravascular macrophages within myocardial small vessels is a feature of acute vascular rejection in human heart transplants. J Heart Lung Transplant. 14:(2):1995;338-345.
6. Hook S., Caple J.F., McMahon J.T., et al. Comparison of myocardial cell injury in acute cellular rejection versus acute vascular rejection in cyclosporine-treated heart transplants. J Heart Lung Transplant. 14:1995;351-358.
7. Taylor D.O., Yowell R.L., Kfoury A.G., et al. Allograft coronary artery disease clinical correlations with circulating anti-HLA antibodies and the immunohistopathologic pattern of vascular rejection . J Heart Lung Transplant. 19:(6):2000;518-521.
8. Cherry R., Nielson H., Reed E., et al. Vascular (humoral) rejection in human cardiac allograft biopsies relationship to circulating anti-HLA antibodies . J Heart Lung Transplant. 11:1992;24-30.
9. Byzova T.V., Rabbani R., D'Souza S.E., Plow E.F. Role of integrin αvβ3 in vascular biology. Thromb Haemost. 80:1998;726-734.
10. Byzova T.V., Plow E.F. Activation of alphaVbeta3 on vascular cells controls recognition of prothrombin. J Cell Biology. 143:(7):1998;2081-2092.
11. Hermann P., Armant M., Brown E., et al. The vitronectin receptor and its associated CD47 molecule mediates proinflammatory cytokine synthesis in human monocytes by interaction with soluble CD23. J Cell Biol. 144:(4):1999;767-775.
12. Mackman N. Regulation of tissue factor gene expression in human monocytic and endothelial cells. Haemostasis. 26:1996;17-19.
13. Rajavashisth T.B., Xu X.P., Jovinge S., et al. Membrane type 1 matrix metalloproteinase expression in human atherosclerotic plaques evidence for activation by proinflammatory mediators . Circulation. 99:(24):1999;3103-3109.
14. Li Y.Y., McTiernan C.F., Feldman A.M. Proinflammatory cytokines regulate tissue inhibitors of metalloproteinases and disintegrin metalloproteinase in cardiac cells. Cardiovasc Res. 42:(1):1999;162-172.
15. Felding-Habermann B., Cheresh D.A. Vitronectin and its receptor. Curr Opin Cell Biol. 5:1993;864-868.
16. Tremoli E., Camera M., Toschi V., et al. Tissue factor in atherosclerosis. Atherosclerosis. 144:(2):1999;273-283.
17. Ries C., Petrides P.E. Cytokine regulation of matrix metalloproteinase activity and regulatory dysfunction in disease. Biol Chem. 376:1995;345-355.
18. Kanda S., Kuzuya M., Ramos M.A., et al. Matrix metalloproteinase and alphaVbeta3 integrin-dependent vascular smooth muscle cell invasion through a type I collagen lattice. Arterioscler Thromb Vasc Biol. 20:(4):2000;998-1005.
19. Hofmann U.B., Westphal J.R., VanKraats A.A., Ruiter D.J., Van Muijen G.N. Expression of integrin alpha(v)beta(3) correlates with activation of membrane-type matrix metalloproteinase-1(MT1-MMP) and matrix metalloproteinase-2 (MMP-2) in human melanoma cells in vitro and in vivo. Int J Cancer. 87:(1):2000;12-19.
20. Cook D.J., Klingman L.L., Koo A.P., et al. Quantitative flow cytometry cross-matching for precise measurement of donor-specific alloreactivity. Transplant Proc. 26:(5):1994;2866-2867.
21. Yang J., Moravec C.S., Sussman M.A., et al. Decreased SLIM1 expression and increased gelsolin expression in failing human hearts measured by high-density oligonucleotide arrays. Circulation. 102:(25):2000;3046-3052.
22. Mallat Z., Hugel B., Ohan J., et al. Shed membrane microparticles with procoagulant potential in human atherosclerotic plaques a role for apoptosis in plaque thrombogenecity . Circulation. 99:(3):1999;348-353.
23. Nagayasu T., Saadi S., Holzknecht R.A., et al. Expression of tissue factor mRNA in cardiac xenografts Clues to the pathogenesis of acute vascular rejection . Transplantation. 69:2000;475-482.
24. Saadi S., Holzknecht R.A., Patte C.P., et al. Complement mediated regulation of tissue factor activity in endothelium. J Exp Med. 182:1995;1807-1811.
25. Nemerson Y. Tissue factor and hemostasis. Blood. 71:1988;71-78.
26. Kitazawa S., Ross F., McHugh K., et al. Interleukin-4 induces expression of the integrin αvβ3 via transactivation of the β3 gene. J Biol Chem. 270:1995;4115-4120.
27. Lindsey M., Wedin K., Brown M.D., et al. Matrix-dependent mechanism of neutrophil-mediated release and activation of matrix metalloproteinase 9 in myocardial ischemia/reperfusion. Circulation. 103:2001;2181-2187.