Identification of novel, functional genetic variants in the human matrix metalloproteinase-2 gene. Role of Sp1 in allele-specific transcriptional regulation

Journal of Biological Chemistry

Volumn 276, Issue 10, 2001, Pages 7549-7558

  Price, Simon J ^a   Greaves, David R ^b   Watkins, Hugh ^a,c  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c JOHN RADCLIFFE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; ELECTROPHORESIS; GENES; GENETIC ENGINEERING; PATHOLOGY; TISSUE;

FUNCTIONAL GENETIC VARIANTS;

ENZYMES;

CIS ACTING ELEMENT; DNA; GELATINASE A; NUCLEAR PROTEIN; TRANSCRIPTION FACTOR SP1;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ANIMAL CELL; ARTICLE; ATHEROGENESIS; BASEMENT MEMBRANE; CANCER INVASION; CONTROLLED STUDY; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; GENE FREQUENCY; GENETIC DISORDER; GENETIC VARIABILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; INTRON; METASTASIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; RAT; REPORTER GENE; SINGLE NUCLEOTIDE POLYMORPHISM; TRANSCRIPTION REGULATION; ALLELE; ANIMAL; BIOLOGICAL MODEL; CELL LINE; CELL NUCLEUS; EXON; FACTUAL DATABASE; GENETIC POLYMORPHISM; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; GENETICS; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY;

ANIMALIA;

3' UNTRANSLATED REGIONS; 5' UNTRANSLATED REGIONS; ALLELES; ANIMALS; CELL LINE; CELL NUCLEUS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DATABASES, FACTUAL; EXONS; GENES, REPORTER; HUMANS; INTRONS; MATRIX METALLOPROTEINASE 2; MICE; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); SP1 TRANSCRIPTION FACTOR; TRANSCRIPTION, GENETIC; TRANSFECTION; VARIATION (GENETICS);

EID: 0035831536     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M010242200     Document Type: Article

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