Effect of plant neutrophil elastase inhibitor on leucocyte migration, adhesion and cytokine release in inflammatory conditions

British Journal of Pharmacology

Volumn 161, Issue 4, 2010, Pages 899-910

  Oliveira, C ^a   Navarro Xavier, R A ^b   Anjos Vallota, E A ^b   Martins, J O ^c   Silveira, V L F ^a   Goncalves L R C ^d   Araujo M S ^a   Motta, G ^a   Sannomiya, P ^c   Oliva, M L V ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b INSTITUTO OSWALDO CRUZ   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

^d INSTITUTO BUTANTAN   (Brazil)

Author keywords

Bauhinia; bradykinin; cytokines; elastase; inflammation; intravital microscopy; Kunitz inhibitor; paw oedema; pleurisy

Indexed keywords

BAUHINIA BAUHINIOIDES SERINE AND CYSTEINE PEPTIDASE INHIBITOR; BRADYKININ; CARRAGEENAN; CATHEPSIN G; CATHEPSIN L; CYTOKINE; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT; ELASTASE; INTERLEUKIN 1BETA; LEUKOCYTE ELASTASE INHIBITOR; PLANT EXTRACT; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BAUHINIA; BLOOD FLOW VELOCITY; CELL INTERACTION; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG ISOLATION; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; HEMODYNAMIC PARAMETERS; INFLAMMATION; LEUKOCYTE ADHERENCE; LEUKOCYTE MIGRATION; MALE; MEAN ARTERIAL PRESSURE; MICROCIRCULATION; MICROSCOPY; NONHUMAN; PAW EDEMA; PLEURA CAVITY; PLEURA FLUID; PLEURISY; PRIORITY JOURNAL; RAT; SCROTUM; SHEAR RATE; VEIN WALL;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BAUHINIA; CARRAGEENAN; CATHEPSIN G; CATHEPSIN L; CELL ADHESION; CELL MOVEMENT; CYTOKINES; DISEASE MODELS, ANIMAL; EDEMA; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; INFLAMMATION; LEUKOCYTE ELASTASE; LEUKOCYTES; MALE; MICROSCOPY; PLANT PROTEINS; RATS; RATS, WISTAR; SEEDS;

EID: 77957225606     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2010.00924.x     Document Type: Article

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