Donor pretreatment with tetrahydrobiopterin saves pancreatic isografts from ischemia reperfusion injury in a mouse model

American Journal of Transplantation

Volumn 10, Issue 10, 2010, Pages 2231-2240

  Maglione, M ^a   Oberhuber, R ^a   Cardini, B ^a   Watschinger, K ^b   Hermann, M ^c   Obrist, P ^d   Hengster, P ^a,c   Mark, W ^a   Schneeberger, S ^a   Werner Felmayer, G ^b   Pratschke, J ^a   Margreiter, R ^a   Werner, E R ^b   Brandacher, G ^a  

^a Transplant and Thoracic Surgery   (United States)

^b Division of Biological Chemistry   (United States)

^c INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^d RESEARCH INSTITUTE OF MOLECULAR PATHOLOGY   (Austria)

Author keywords

Animal models; donor preconditioning; endothelial dysfunction; endothelial nitric oxide synthase; ischemia reperfusion injury; mice; nitric oxide; oxidative stress; pancreas transplantation

Indexed keywords

3 NITROTYROSINE; PEROXYNITRITE; TETRAHYDROBIOPTERIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENDOCRINE FUNCTION; GRAFT RECIPIENT; GRAFT SURVIVAL; HISTOPATHOLOGY; ISCHEMIA; ISOGRAFT; MALE; MICROCIRCULATION; MOUSE; NONHUMAN; PANCREAS TRANSPLANTATION; PARENCHYMA; PRIORITY JOURNAL; REPERFUSION INJURY; SURVIVAL RATE; TISSUE INJURY;

ANIMALS; BIOPTERIN; COLD ISCHEMIA; MALE; MICE; MICE, INBRED C57BL; MICROCIRCULATION; MODELS, ANIMAL; PANCREAS; PANCREAS TRANSPLANTATION; PEROXYNITROUS ACID; REPERFUSION INJURY; TISSUE DONORS; TRANSPLANTATION, ISOGENEIC; TYROSINE;

EID: 77957199464     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2010.03262.x     Document Type: Article

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