Conjugated PDT drug: Photosensitizing activity and tissue distribution of PEGylated pheophorbide a

Cancer Biology and Therapy

Volumn 10, Issue 5, 2010, Pages 471-482

  Rapozzi, Valentina ^a   Zacchigna, Marina ^b   Biffi, Stefania ^c   Garrovo, Chiara ^c   Cateni, Francesca ^b   Stebel, Marco ^b   Zorzet, Sonia ^b   Bonora, Gian Maria ^b   Drioli, Sara ^b   Xodo, Luigi E ^a  

^a UNIVERSITY OF UDINE   (Italy)

^b Department of Pharmaceutical Science ^*  (Italy)

^c CBM   (Italy)

Author keywords

Biodistribution; In vivo imaging; PDT; PEGylated pheophorbide a; Phototoxicity

Indexed keywords

METHOXYPOLYETHYLENE GLYCOL PHEOPHORBIDE A; PHEOPHORBIDE; PHEOPHORBIDE A; PHOTOSENSITIZING AGENT; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL DAMAGE; CELL PROLIFERATION; CLINICAL EVALUATION; CYTOTOXICITY; DRUG ACCUMULATION; DRUG BRAIN LEVEL; DRUG DESIGN; DRUG DISTRIBUTION; DRUG LIVER LEVEL; DRUG MECHANISM; DRUG SOLUBILITY; DRUG STABILITY; DRUG STRUCTURE; DRUG UPTAKE; DUODENUM; FEMALE; HUMAN; HUMAN CELL; IC 50; IN VIVO STUDY; KIDNEY; LIPID PEROXIDATION; LUNG; MELANOMA; MITOCHONDRION; MOUSE; NONHUMAN; PHOTOACTIVATION; PHOTODYNAMIC THERAPY; PHOTOSENSITIZATION; SPLEEN; TISSUE DISTRIBUTION; TREATMENT OUTCOME;

ANIMALS; ANTINEOPLASTIC AGENTS; CHLOROPHYLL; FEMALE; HELA CELLS; HEP G2 CELLS; HUMANS; INJECTIONS, INTRAPERITONEAL; MALONDIALDEHYDE; MICE; MITOCHONDRIAL MEMBRANES; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; POLYETHYLENE GLYCOLS; REACTIVE OXYGEN SPECIES; TISSUE DISTRIBUTION; TUMOR CELLS, CULTURED;

EID: 77957109697     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.10.5.12536     Document Type: Article

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