메뉴 건너뛰기




Volumn 3, Issue , 2009, Pages 205-214

Dasatinib in the treatment of imatinib refractory chronic myeloid leukemia

Author keywords

Chronic myeloid leukemia (CML); Dasatinib; Imatinib; Nilotinib; Resistance (imatinib resistance); Tyrosine kinase inhibitor

Indexed keywords


EID: 77957067159     PISSN: 11775475     EISSN: 11775491     Source Type: Journal    
DOI: 10.2147/BTT.S3791     Document Type: Review
Times cited : (9)

References (55)
  • 1
    • 33745102555 scopus 로고    scopus 로고
    • Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias
    • Talpaz M, Shah NP, et al. 2006. Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias. N Engl J Med. 354(24):2531-2541.
    • (2006) N Engl J Med. , vol.354 , Issue.24 , pp. 2531-2541
    • Talpaz, M.1    Shah, N.P.2
  • 2
    • 45149087139 scopus 로고    scopus 로고
    • Dasatinib induces durable cytogenetic responses in patients with chronic myelogenous leukemia in chronic phase with resistance or intolerance to imatinib
    • Hochhaus A, Baccarani M, et al. Dasatinib induces durable cytogenetic responses in patients with chronic myelogenous leukemia in chronic phase with resistance or intolerance to imatinib. Leukemia. 2008;22(6):1200-1206.
    • (2008) Leukemia. , vol.22 , Issue.6 , pp. 1200-1206
    • Hochhaus, A.1    Baccarani, M.2
  • 3
    • 34447544253 scopus 로고    scopus 로고
    • BCR-ABL tyrosine kinase inhibitors for chronic myelogenous leukemia
    • Schiffer CA. BCR-ABL tyrosine kinase inhibitors for chronic myelogenous leukemia. N Engl J Med. 2007;357(3):258-265.
    • (2007) N Engl J Med. , vol.357 , Issue.3 , pp. 258-265
    • Schiffer, C.A.1
  • 4
    • 33845444046 scopus 로고    scopus 로고
    • Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia
    • Druker BJ, Guilhot F, et al. 2006. Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia. N Engl J Med. 355(23):2408-2417.
    • (2006) N Engl J Med. , vol.355 , Issue.23 , pp. 2408-2417
    • Druker, B.J.1    Guilhot, F.2
  • 5
    • 35748952533 scopus 로고    scopus 로고
    • Dasatinib: A new step in molecular target therapy
    • Olivieri, A, Manzione L. Dasatinib: a new step in molecular target therapy. Ann Oncol. 2007;18 Suppl 6:vi42-46.
    • (2007) Ann Oncol. , vol.18 , Issue.SUPPL. 6
    • Olivieri, A.1    Manzione, L.2
  • 6
    • 51649120694 scopus 로고    scopus 로고
    • Therapeutic options against BCR-ABL1 T315I-positive chronic myelogenous leukemia
    • Quintas-Cardama A, Cortes J. Therapeutic options against BCR-ABL1 T315I-positive chronic myelogenous leukemia. Clin Cancer Res. 2008;14(14):4392-4399.
    • (2008) Clin Cancer Res. , vol.14 , Issue.14 , pp. 4392-4399
    • Quintas-Cardama, A.1    Cortes, J.2
  • 7
    • 45549088374 scopus 로고    scopus 로고
    • Management of patients with resistant or refractory chronic myelogenous leukemia
    • discussion 437, 442, 446 passim
    • Quintas-Cardama A, Cortes J. Management of patients with resistant or refractory chronic myelogenous leukemia. Oncology (Williston Park). 2008;22(4):430-7; discussion 437, 442, 446 passim.
    • (2008) Oncology (Williston Park). , vol.22 , Issue.4 , pp. 430-437
    • Quintas-Cardama, A.1    Cortes, J.2
  • 8
    • 2942567555 scopus 로고    scopus 로고
    • Treatment of Philadelphia chromosome-positive acute lymphocytic leukemia with hyper-CVAD and imatinib mesylate
    • Thomas DA, Faderl S. Treatment of Philadelphia chromosome-positive acute lymphocytic leukemia with hyper-CVAD and imatinib mesylate. Blood, 2004;103(12):4396-4407.
    • (2004) Blood , vol.103 , Issue.12 , pp. 4396-4407
    • Thomas, D.A.1    Faderl, S.2
  • 9
    • 0037438640 scopus 로고    scopus 로고
    • BCR-ABL independence and LYN kinase overexpression in chronic myelogenous leukemia cells selected for resistance to STI571
    • Donato NJ, Wu JY, et al. BCR-ABL independence and LYN kinase overexpression in chronic myelogenous leukemia cells selected for resistance to STI571. Blood. 2003;101(2):690-698.
    • (2003) Blood. , vol.101 , Issue.2 , pp. 690-698
    • Donato, N.J.1    Wu, J.Y.2
  • 10
    • 51649111035 scopus 로고    scopus 로고
    • Dasatinib crosses the blood-brain barrier and is an efficient therapy for central nervous system Philadelphia chromosome-positive leukemia
    • Porkka, K, Koskenvesa, P, et al. Dasatinib crosses the blood-brain barrier and is an efficient therapy for central nervous system Philadelphia chromosome-positive leukemia. Blood. 2008;112(4): 1005-12.
    • (2008) Blood. , vol.112 , Issue.4 , pp. 1005-1012
    • Porkka, K.1    Koskenvesa, P.2
  • 11
    • 61449158211 scopus 로고    scopus 로고
    • A phase II study of dasatinib in relapsed and refractory chronic lymphocytic leukemia (CLL/SLL)
    • ASH Annual Meeting Abstracts
    • Amrein PC, Attar EC, et al. A phase II study of dasatinib in relapsed and refractory chronic lymphocytic leukemia (CLL/SLL). Blood. (ASH Annual Meeting Abstracts). 2007;110:3126.
    • (2007) Blood , vol.110 , pp. 3126
    • Amrein, P.C.1    Attar, E.C.2
  • 12
    • 68449090883 scopus 로고    scopus 로고
    • Phase I trial evaluating the epidermal growth factor receptor inhibitor erlotinib in combination with the SRC kinase inhibitor dasatinib for patients with recurrent nonsmall cell lung cancer (NSCLC)
    • MAY 20, abstr 14605
    • Chiappori AA, Tanvetyanon T, et al. Phase I trial evaluating the epidermal growth factor receptor inhibitor erlotinib in combination with the SRC kinase inhibitor dasatinib for patients with recurrent nonsmall cell lung cancer (NSCLC). J Clin Oncol. 2008;26(May 20 suppl): abstr 14605.
    • (2008) J Clin Oncol. , vol.26 , Issue.SUPPL.
    • Chiappori, A.A.1    Tanvetyanon, T.2
  • 13
    • 84900548823 scopus 로고    scopus 로고
    • Phase I trial of cetuximab (C) and dasatinib (D) in patients (pts) with advanced solid malignancies
    • MAY 20, abstr 14668
    • Esteve FR, Stoller RG, et al. 2008. Phase I trial of cetuximab (C) and dasatinib (D) in patients (pts) with advanced solid malignancies. J Clin Oncol. 2008;26(May 20 suppl):abstr 14668.
    • (2008) J Clin Oncol. 2008 , vol.26 , Issue.SUPPL.
    • Esteve, F.R.1    Stoller, R.G.2
  • 14
    • 84993796265 scopus 로고    scopus 로고
    • Phase I study of Src inhibition with dasatinib in combination with 5-fluoruracil, leucovorin, oxaliplatin (FOLFOX) and cetuximab in metastatic colorectal cancer
    • Abstract No: 325
    • Kopetz S, Wolff RA, et al. Phase I study of Src inhibition with dasatinib in combination with 5-fluoruracil, leucovorin, oxaliplatin (FOLFOX) and cetuximab in metastatic colorectal cancer. ASCO Gastrointestinal Symposium. 2008;Abstract No: 325.
    • (2008) ASCO Gastrointestinal Symposium
    • Kopetz, S.1    Wolff, R.A.2
  • 15
    • 59249108004 scopus 로고    scopus 로고
    • Dasatinib in patients with hormonerefractory progressive prostate cancer: A phase II study
    • MAY 20, abstr 5156
    • Yu EY, Wilding G, et al. Dasatinib in patients with hormonerefractory progressive prostate cancer: A phase II study. J Clin Oncol. 2008;26(May 20 suppl):abstr 5156.
    • (2008) J Clin Oncol. , vol.26 , Issue.SUPPL.
    • Yu, E.Y.1    Wilding, G.2
  • 16
    • 61449151432 scopus 로고    scopus 로고
    • Dasatinib induces apoptosis in chronic lymphocytic leukemia and enhances the activity of rituximab and fludarabine
    • ASH Annual Meeting Abstracts
    • Aguillon RA, Llanos CA, et al. Dasatinib induces apoptosis in chronic lymphocytic leukemia and enhances the activity of rituximab and fludarabine. Blood. (ASH Annual Meeting Abstracts). 2007;110:1116.
    • (2007) Blood , vol.110 , pp. 1116
    • Aguillon, R.A.1    Llanos, C.A.2
  • 17
    • 84900525579 scopus 로고    scopus 로고
    • Dasatinib inhibits the growth of neoplastic human eosinophils (EOL-1) through targeting of FIP1L1-PDGFR
    • ASH Annual Meeting Abstracts
    • Baumgartner C, Gleixner KV, et al. Dasatinib inhibits the growth of neoplastic human eosinophils (EOL-1) through targeting of FIP1L1-PDGFR. Blood. (ASH Annual Meeting Abstracts). 2007;110:3559.
    • (2007) Blood , vol.110 , pp. 3559
    • Baumgartner, C.1    Gleixner, K.V.2
  • 18
    • 47949104247 scopus 로고    scopus 로고
    • Response to dasatinib in patients with aggressive systemic mastocytosis with D816V kit mutation
    • ASH Annual Meeting Abstracts
    • Rondoni M, Paolini S, et al. Response to dasatinib in patients with aggressive systemic mastocytosis with D816V kit mutation. Blood. (ASH Annual Meeting Abstracts). 2007;110:3562.
    • (2007) Blood , vol.110 , pp. 3562
    • Rondoni, M.1    Paolini, S.2
  • 19
    • 56449121145 scopus 로고    scopus 로고
    • The activity and toxicity of dasatinib in relapsed or plateau-phase multiple myeloma
    • ASH Annual Meeting Abstracts
    • Wildes TM, Ruddell A, et al. The activity and toxicity of dasatinib in relapsed or plateau-phase multiple myeloma. Blood. (ASH Annual Meeting Abstracts). 2007;110:1182.
    • (2007) Blood , vol.110 , pp. 1182
    • Wildes, T.M.1    Ruddell, A.2
  • 20
    • 84900548858 scopus 로고    scopus 로고
    • Dasatinib (sprycell) for CML and Ph22ALL
    • Dasatinib (sprycell) for CML and Ph22ALL. Med Lett Drugs Ther 2007;49:1252.
    • (2007) Med Lett Drugs Ther , vol.49 , pp. 1252
  • 21
    • 33744486584 scopus 로고    scopus 로고
    • Dasatinib (BMS-354825) targets an earlier progenitor population than imatinib in primary CML but does not eliminate the quiescent fraction
    • Copland M, Hamilton A, et al. Dasatinib (BMS-354825) targets an earlier progenitor population than imatinib in primary CML but does not eliminate the quiescent fraction. Blood. 2006;107(11):4532-4539.
    • (2006) Blood. , vol.107 , Issue.11 , pp. 4532-4539
    • Copland, M.1    Hamilton, A.2
  • 23
    • 33947280081 scopus 로고    scopus 로고
    • Dasatinib induces notable hematologic and cytogenetic responses in chronic-phase chronic myeloid leukemia after failure of imatinib therapy
    • Hochhaus A, Kantarjian HM, et al. Dasatinib induces notable hematologic and cytogenetic responses in chronic-phase chronic myeloid leukemia after failure of imatinib therapy. Blood. 2007;109(6): 2303-2309.
    • (2007) Blood. , vol.109 , Issue.6 , pp. 2303-2309
    • Hochhaus, A.1    Kantarjian, H.M.2
  • 24
    • 54949154484 scopus 로고    scopus 로고
    • Dasatinib 2-year efficacy in patients with chronic-phase chronic myelogenous leukemia (CML-CP) with resistance or intolerance to imatinib (START-C)
    • MAY 20, abstr 7009
    • Mauro MJ, Baccarani M, et al. Dasatinib 2-year efficacy in patients with chronic-phase chronic myelogenous leukemia (CML-CP) with resistance or intolerance to imatinib (START-C). J Clin Oncol. 2008;26(May 20 suppl):abstr 7009.
    • (2008) J Clin Oncol. , vol.26 , Issue.SUPPL.
    • Mauro, M.J.1    Baccarani, M.2
  • 25
    • 41349123259 scopus 로고    scopus 로고
    • Monitoring the response and course of chronic myeloid leukemia in the modern era of BCR-ABL tyrosine kinase inhibitors: Practical advice on the use and interpretation of monitoring methods
    • Kantarjian H, Schiffer C, et al. Monitoring the response and course of chronic myeloid leukemia in the modern era of BCR-ABL tyrosine kinase inhibitors: practical advice on the use and interpretation of monitoring methods. Blood. 2008;111(4):1774-1780.
    • (2008) Blood. , vol.111 , Issue.4 , pp. 1774-1780
    • Kantarjian, H.1    Schiffer, C.2
  • 26
    • 34248324467 scopus 로고    scopus 로고
    • Dasatinib induces significant hematologic and cytogenetic responses in patients with imatinib-resistant or-intolerant chronic myeloid leukemia in accelerated phase
    • Guilhot F, Apperley J, et al. Dasatinib induces significant hematologic and cytogenetic responses in patients with imatinib-resistant or-intolerant chronic myeloid leukemia in accelerated phase. Blood. 2007;109(10):4143-4150.
    • (2007) Blood. , vol.109 , Issue.10 , pp. 4143-4150
    • Guilhot, F.1    Apperley, J.2
  • 27
    • 49249109701 scopus 로고    scopus 로고
    • Efficacy of dasatinib in patients with accelerated phase chronic myelogenous leukemia with resistance or intolerance to imatinib: 2 year follow-up data from START-A (CA180-005)
    • (ASH Annual Meeting Abstracts Nov 2007)
    • Guilhot F, Apperley J, et al. Efficacy of dasatinib in patients with accelerated phase chronic myelogenous leukemia with resistance or intolerance to imatinib: 2 year follow-up data from START-A (CA180-005). Blood (ASH Annual Meeting Abstracts Nov 2007). 2008;110:470.
    • (2008) Blood , vol.110 , pp. 470
    • Guilhot, F.1    Apperley, J.2
  • 28
    • 33947356135 scopus 로고    scopus 로고
    • Dasatinib induces complete hematologic and cytogenetic responses in patients with imatinib-resistant or-intolerant chronic myeloid leukemia in blast crisis
    • Cortes J, Rousselot P, et al. Dasatinib induces complete hematologic and cytogenetic responses in patients with imatinib-resistant or-intolerant chronic myeloid leukemia in blast crisis. Blood. 2007;109(8):3207-3213.
    • (2007) Blood. , vol.109 , Issue.8 , pp. 3207-3213
    • Cortes, J.1    Rousselot, P.2
  • 29
    • 58649117545 scopus 로고    scopus 로고
    • Efficacy and safety of dasatinib in patients with chronic myeloid leukemia in blast phase whose disease is resistant or intolerant to imatinib: 2-year follow-up data from the START Program
    • ASH Annual Meeting Abstracts
    • Gambacorti C, Cortes J, et al. Efficacy and safety of dasatinib in patients with chronic myeloid leukemia in blast phase whose disease is resistant or intolerant to imatinib: 2-year follow-up data from the START Program. Blood. (ASH Annual Meeting Abstracts). 2007;110:472.
    • (2007) Blood , vol.110 , pp. 472
    • Gambacorti, C.1    Cortes, J.2
  • 30
    • 34948829146 scopus 로고    scopus 로고
    • Dasatinib induces rapid hematologic and cytogenetic responses in adult patients with Philadelphia chromosome positive acute lymphoblastic leukemia with resistance or intolerance to imatinib: Interim results of a phase 2 study
    • Ottmann O, Dombret H, et al. Dasatinib induces rapid hematologic and cytogenetic responses in adult patients with Philadelphia chromosome positive acute lymphoblastic leukemia with resistance or intolerance to imatinib: interim results of a phase 2 study. Blood. 2007;110(7):2309-2315.
    • (2007) Blood. , vol.110 , Issue.7 , pp. 2309-2315
    • Ottmann, O.1    Dombret, H.2
  • 31
    • 47849116810 scopus 로고    scopus 로고
    • Dasatinib as front-line monotherapy for the induction treatment of adult and elderly Phiiacute lymphoblastic leukemia (ALL) patients: Interim analysis of the GIMEMA Prospective Study LAL1205
    • ASH Annual Meeting Abstracts
    • Foa R, Vignetti M, et al. Dasatinib as front-line monotherapy for the induction treatment of adult and elderly Phiiacute lymphoblastic leukemia (ALL) patients: interim analysis of the GIMEMA Prospective Study LAL1205. Blood. (ASH Annual Meeting Abstracts). 2007;110:7.
    • (2007) Blood , vol.110 , pp. 7
    • Foa, R.1    Vignetti, M.2
  • 32
    • 47549105329 scopus 로고    scopus 로고
    • Phase II study of combination of the hyperCVAD regimen with dasatinib in patients with Philadelphia chromosome (Ph) or BCR-ABL positive acute lymphoblastic leukemia (ALL) and lymphoid blast phase chronic myeloid leukemia (CML-LB)
    • ASH Annual Meeting Abstracts
    • Ravandi F, Thomas D, et al. Phase II study of combination of the hyperCVAD regimen with dasatinib in patients with Philadelphia chromosome (Ph) or BCR-ABL positive acute lymphoblastic leukemia (ALL) and lymphoid blast phase chronic myeloid leukemia (CML-LB). Blood. (ASH Annual Meeting Abstracts). 2007;110:2814.
    • (2007) Blood , vol.110 , pp. 2814
    • Ravandi, F.1    Thomas, D.2
  • 33
    • 49249109701 scopus 로고    scopus 로고
    • Efficacy of dasatinib in patients with chronic-phase chronic myelogenous leukemia with resistance or intolerance to imatinib: 2-year follow-up data from START-C (CA180-013)
    • Stone RM, Kantarjian HM, et al. Efficacy of dasatinib in patients with chronic-phase chronic myelogenous leukemia with resistance or intolerance to imatinib: 2-year follow-up data from START-C (CA180-013). Blood (ASH Annual Meeting Abstracts). 2007;110:734.
    • (2007) Blood (ASH Annual Meeting Abstracts). , vol.110 , pp. 734
    • Stone, R.M.1    Kantarjian, H.M.2
  • 34
    • 34548523623 scopus 로고    scopus 로고
    • Pleural effusion in patients with chronic myelogenous leukemia treated with dasatinib after imatinib failure
    • Quintas-Cardama A, Kantarjian H, et al. Pleural effusion in patients with chronic myelogenous leukemia treated with dasatinib after imatinib failure. J Clin Oncol. 2007;25(25):3908-3914.
    • (2007) J Clin Oncol. , vol.25 , Issue.25 , pp. 3908-3914
    • Quintas-Cardama, A.1    Kantarjian, H.2
  • 35
    • 70350104375 scopus 로고    scopus 로고
    • Pleural effusions associated with use of dasatinib in chronic myeloid leukemia may have an autoimmune pathogenesis
    • ASH Annual Meeting Abstracts
    • Punnialingam S, de Lavallade H, et al. Pleural effusions associated with use of dasatinib in chronic myeloid leukemia may have an autoimmune pathogenesis. Blood. (ASH Annual Meeting Abstracts). 2007;110:2945.
    • (2007) Blood , vol.110 , pp. 2945
    • Punnialingam, S.1    de Lavallade, H.2
  • 36
    • 65249125980 scopus 로고    scopus 로고
    • Clonal large granular lymphocyte (LGL) expansion associated with dasatinib therapy
    • ASH Annual Meeting Abstracts
    • Mustjoki S, Laurinolli T, et al. Clonal large granular lymphocyte (LGL) expansion associated with dasatinib therapy. Blood. (ASH Annual Meeting Abstracts). 2007;110:2938.
    • (2007) Blood , vol.110 , pp. 2938
    • Mustjoki, S.1    Laurinolli, T.2
  • 37
    • 0037307095 scopus 로고    scopus 로고
    • The influence of the src-family kinases, Lck and Fyn, on T cell differentiation, survival and activation
    • Zamoyska R, Basson A, et al. The influence of the src-family kinases, Lck and Fyn, on T cell differentiation, survival and activation. Immunol Rev. 2003;191:107-118.
    • (2003) Immunol Rev. , vol.191 , pp. 107-118
    • Zamoyska, R.1    Basson, A.2
  • 38
    • 49249121723 scopus 로고    scopus 로고
    • Intermittent target inhibition with dasatinib 100 mg once daily preserves efficacy and improves tolerability in imatinib-resistant and-intolerant chronic-phase chronic myeloid leukemia
    • Shah NP, Kantarjian HM, et al. Intermittent target inhibition with dasatinib 100 mg once daily preserves efficacy and improves tolerability in imatinib-resistant and-intolerant chronic-phase chronic myeloid leukemia. J Clin Oncol. 2008;26(19):3204-3212.
    • (2008) J Clin Oncol. , vol.26 , Issue.19 , pp. 3204-3212
    • Shah, N.P.1    Kantarjian, H.M.2
  • 40
    • 34249074686 scopus 로고    scopus 로고
    • Dasatinib or high-dose imatinib for chronicphase chronic myeloid leukemia after failure of first-line imatinib: A randomized phase 2 trial
    • Kantarjian H, Pasquini R, et al. Dasatinib or high-dose imatinib for chronicphase chronic myeloid leukemia after failure of first-line imatinib: a randomized phase 2 trial. Blood. 2007;109(12):5143-5150.
    • (2007) Blood. , vol.109 , Issue.12 , pp. 5143-5150
    • Kantarjian, H.1    Pasquini, R.2
  • 41
    • 34247248807 scopus 로고    scopus 로고
    • Outcome of patients with Philadelphia chromosome-positive chronic myelogenous leukemia post-imatinib mesylate failure
    • Kantarjian H, O'Brien S, et al. Outcome of patients with Philadelphia chromosome-positive chronic myelogenous leukemia post-imatinib mesylate failure. Cancer. 2007;109(8):1556-1560.
    • (2007) Cancer. , vol.109 , Issue.8 , pp. 1556-1560
    • Kantarjian, H.1    O'Brien, S.2
  • 42
    • 33745086350 scopus 로고    scopus 로고
    • Nilotinib in imatinib-resistant CML and Philadelphia chromosome-positive ALL
    • Kantarjian H, Giles F, et al. Nilotinib in imatinib-resistant CML and Philadelphia chromosome-positive ALL. N Engl J Med. 2006;354(24):2542-2551.
    • (2006) N Engl J Med. , vol.354 , Issue.24 , pp. 2542-2551
    • Kantarjian, H.1    Giles, F.2
  • 43
    • 43549116467 scopus 로고    scopus 로고
    • Nilotinib Is highly active and safe in chronic phase chronic myelogenous leukemia (CML-CP) patients with imatinib-resistance or intolerance
    • ASH Annual Meeting Abstracts
    • Kantarjian H, Hochhaus A, et al. Nilotinib Is highly active and safe in chronic phase chronic myelogenous leukemia (CML-CP) patients with imatinib-resistance or intolerance. Blood. (ASH Annual Meeting Abstracts). 2007;110:735.
    • (2007) Blood , vol.110 , pp. 735
    • Kantarjian, H.1    Hochhaus, A.2
  • 44
    • 43549107806 scopus 로고    scopus 로고
    • Nilotinib is safe and effective in accelerated phase chronic myelogenous leukemia (CML-AP) patients with imatinib resistance or intolerance
    • ASH Annual Meeting Abstracts
    • Le Coutre P, Giles FJ, et al. Nilotinib is safe and effective in accelerated phase chronic myelogenous leukemia (CML-AP) patients with imatinib resistance or intolerance. Blood. (ASH Annual Meeting Abstracts). 2007;110:471.
    • (2007) Blood , vol.110 , pp. 471
    • Le Coutre, P.1    Giles, F.J.2
  • 45
    • 43549112174 scopus 로고    scopus 로고
    • Nilotinib in patients (pts) with Philadelphia chromosome-positive (Phc) chronic myelogenous leukemia in blast crisis (CML-BC) who are resistant or intolerant to imatinib
    • ASH Annual Meeting Abstracts
    • Giles FJ, Larson RA, et al. Nilotinib in patients (pts) with Philadelphia chromosome-positive (Phc) chronic myelogenous leukemia in blast crisis (CML-BC) who are resistant or intolerant to imatinib. Blood. (ASH Annual Meeting Abstracts). 2007;110:1025.
    • (2007) Blood , vol.110 , pp. 1025
    • Giles, F.J.1    Larson, R.A.2
  • 46
    • 65749091319 scopus 로고    scopus 로고
    • P-loop mutations and novel therapeutic approaches for imatinib failures in chronic myeloid leukemia
    • Cang S, Liu D. P-loop mutations and novel therapeutic approaches for imatinib failures in chronic myeloid leukemia. J Hematol Oncol. 2008;1:15.
    • (2008) J Hematol Oncol. , vol.1 , pp. 15
    • Cang, S.1    Liu, D.2
  • 47
    • 33846847772 scopus 로고    scopus 로고
    • Resistance to targeted therapy in chronic myelogenous leukemia
    • Hochhaus A, Erben P, et al. Resistance to targeted therapy in chronic myelogenous leukemia. Semin Hematol; 2007;44(1 Suppl 1): S15-S24.
    • (2007) Semin Hematol; , vol.44 , Issue.1 SUPPL. 1
    • Hochhaus, A.1    Erben, P.2
  • 51
    • 47149088793 scopus 로고    scopus 로고
    • Efficacy of nilotinib (AMN107) in patients (pts) with newly diagnosed, previously untreated philadelphia chromosome (Ph)-positive chronic myelogenous leukemia in early chronic phase (CML-CP)
    • Cortes J, O'Brien S, et al. Efficacy of nilotinib (AMN107) in patients (pts) with newly diagnosed, previously untreated philadelphia chromosome (Ph)-positive chronic myelogenous leukemia in early chronic phase (CML-CP). Blood (ASH Annual Meeting Abstracts). 2007;110:29.
    • (2007) Blood (ASH Annual Meeting Abstracts). , vol.110 , pp. 29
    • Cortes, J.1    O'Brien, S.2
  • 52
    • 47149088793 scopus 로고    scopus 로고
    • Efficacy of dasatinib in patients (pts) with previously untreated chronic myelogenous leukemia (CML) in early chronic phase (CML-CP)
    • Cortes J, O'Brien S, et al. Efficacy of dasatinib in patients (pts) with previously untreated chronic myelogenous leukemia (CML) in early chronic phase (CML-CP). Blood (ASH Annual Meeting Abstracts). 2007;110:30.
    • (2007) Blood (ASH Annual Meeting Abstracts). , vol.110 , pp. 30
    • Cortes, J.1    O'Brien, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.