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MK-0457, a novel multikinase inhibitor, is active in patients with chronic myeloid leukemia (CML) and acute lymphocytic leukemia (ALL) with the T315I BCR-ABL resistance mutation and patients with refractory JAK2-positive myeloproliferative diseases (MPD)
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(EHA Annual Meeting Abstracts) Abstract 0927
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Giles J, Cortes J, Bergstrom DA, Xiao A, Jones D, Verstovsek S, Thomas D, Rizzieri D, Freedman SJ, Kantarjian H: MK-0457, a novel multikinase inhibitor, is active in patients with chronic myeloid leukemia (CML) and acute lymphocytic leukemia (ALL) with the T315I BCR-ABL resistance mutation and patients with refractory JAK2-positive myeloproliferative diseases (MPD). Haematologica (EHA Annual Meeting Abstracts) 2007, 92:347-347. Abstract 0927.
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Thomas, D.7
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Freedman, S.J.9
Kantarjian, H.10
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PHA-739358, an aurora kinase inhibitor, induces clinical responses in chronic myeloid leukemia harboring T315I mutations of BCR-ABL
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(ASH Annual Meeting Abstracts) Abstract 1030
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Paquette R, Shah NP, Sawyers CL, Martinelli G, John N, Chalukya M, Rocchetti M, Fiocchi C, Comis S, Capolongo L, Laffranchi B: PHA-739358, an aurora kinase inhibitor, induces clinical responses in chronic myeloid leukemia harboring T315I mutations of BCR-ABL. Blood (ASH Annual Meeting Abstracts) 2007, 110:. Abstract 1030.
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Fiocchi, C.8
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Laffranchi, B.11
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Orally active inhibitors of the imatinib resistant Bcr-Abl mutant T3151
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(ASH Annual Meeting Abstracts) Abstract 2180
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Shakespeare WC, Wang F, Xu Q, Zhu X, Narasimham N, Metcalf CA, Wang Y, Sundaramoorthi R, Huang W, Zou D, Thomas M, Romero J, Wen D, Chen I, Cai L, Liu S, Wardwell S, Ning Y, Keats J, Snodgrass J, Russian K, Broudy M, O'Hare T, Smith C, Corbin A, Druker B, Iuliucci J, Dalgarno D, Sawyer TK, Clackson T: Orally active inhibitors of the imatinib resistant Bcr-Abl mutant T3151. Blood (ASH Annual Meeting Abstracts) 2006, 108:. Abstract 2180.
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Wang, Y.7
Sundaramoorthi, R.8
Huang, W.9
Zou, D.10
Thomas, M.11
Romero, J.12
Wen, D.13
Chen, I.14
Cai, L.15
Liu, S.16
Wardwell, S.17
Ning, Y.18
Keats, J.19
Snodgrass, J.20
Russian, K.21
Broudy, M.22
O'Hare, T.23
Smith, C.24
Corbin, A.25
Druker, B.26
Iuliucci, J.27
Dalgarno, D.28
Sawyer, T.K.29
Clackson, T.30
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Zhang, W.1
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