메뉴 건너뛰기




Volumn 299, Issue 3, 2010, Pages

PepT1 mediates transport of the proinflammatory bacterial tripeptide L-Ala-γ-D-Glu-meso-DAP in intestinal epithelial cells

Author keywords

Inflammation; Inflammatory bowel diseases

Indexed keywords

ALANYL GAMMA DEXTRO GLUTAMYLMESODIAMINOPIMELIC ACID; BACTERIAL PROTEIN; GLYCINE; PEPTIDE TRANSPORTER 1; SARCOSINE; SHORT HAIRPIN RNA; TETRACYCLINE; UNCLASSIFIED DRUG; COTRANSPORTER;

EID: 77957000911     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00527.2009     Document Type: Article
Times cited : (64)

References (35)
  • 4
    • 33646858115 scopus 로고    scopus 로고
    • The oligopeptide transporter hPepT1: Gateway to the innate immune response
    • Charrier L, Merlin D. The oligopeptide transporter hPepT1: gateway to the innate immune response. Lab Invest 86: 538-546, 2006.
    • (2006) Lab Invest , vol.86 , pp. 538-546
    • Charrier, L.1    Merlin, D.2
  • 8
    • 1242272750 scopus 로고    scopus 로고
    • The proton oligopeptide cotransporter family SLC15 in physiology and pharmacology
    • Daniel H, Kottra G. The proton oligopeptide cotransporter family SLC15 in physiology and pharmacology. Pflügers Arch 447: 610-618, 2004.
    • (2004) Pflügers Arch , vol.447 , pp. 610-618
    • Daniel, H.1    Kottra, G.2
  • 15
    • 0030636792 scopus 로고    scopus 로고
    • Evidence for altered regulation of I kappa B alpha degradation in human colonic epithelial cells
    • Jobin C, Haskill S, Mayer L, Panja A, Sartor RB. Evidence for altered regulation of I kappa B alpha degradation in human colonic epithelial cells. J Immunol 158: 226-234, 1997.
    • (1997) J Immunol , vol.158 , pp. 226-234
    • Jobin, C.1    Haskill, S.2    Mayer, L.3    Panja, A.4    Sartor, R.B.5
  • 16
    • 33748857158 scopus 로고    scopus 로고
    • Neutrophil infiltration and chemokines
    • Kobayashi Y. Neutrophil infiltration and chemokines. Crit Rev Immunol 26: 307-316, 2006.
    • (2006) Crit Rev Immunol , vol.26 , pp. 307-316
    • Kobayashi, Y.1
  • 17
    • 69949125920 scopus 로고    scopus 로고
    • pH-dependent internalization of muramyl peptides from early endosomes enables Nod1 and Nod2 signaling
    • Lee J, Tattoli I, Wojtal KA, Vavricka SR, Philpott DJ, Girardin SE. pH-dependent internalization of muramyl peptides from early endosomes enables Nod1 and Nod2 signaling. J Biol Chem 284: 23818-23829, 2009.
    • (2009) J Biol Chem , vol.284 , pp. 23818-23829
    • Lee, J.1    Tattoli, I.2    Wojtal, K.A.3    Vavricka, S.R.4    Philpott, D.J.5    Girardin, S.E.6
  • 19
    • 0035011324 scopus 로고    scopus 로고
    • Colonic epithelial hPepT1 expression occurs in inflammatory bowel disease: Transport of bacterial peptides influences expression of MHC class 1 molecules
    • Merlin D, Si-Tahar M, Sitaraman SV, Eastburn K, Williams I, Liu X, Hediger MA, Madara JL. Colonic epithelial hPepT1 expression occurs in inflammatory bowel disease: transport of bacterial peptides influences expression of MHC class 1 molecules. Gastroenterology 120: 1666-1679, 2001.
    • (2001) Gastroenterology , vol.120 , pp. 1666-1679
    • Merlin, D.1    Si-Tahar, M.2    Sitaraman, S.V.3    Eastburn, K.4    Williams, I.5    Liu, X.6    Hediger, M.A.7    Madara, J.L.8
  • 20
    • 0032435805 scopus 로고    scopus 로고
    • hPepT1-mediated epithelial transport of bacteria-derived chemotactic peptides enhances neutrophil-epithelial interactions
    • Merlin D, Steel A, Gewirtz AT, Si-Tahar M, Hediger MA, Madara JL. hPepT1-mediated epithelial transport of bacteria-derived chemotactic peptides enhances neutrophil-epithelial interactions. J Clin Invest 102: 2011-2018, 1998.
    • (1998) J Clin Invest , vol.102 , pp. 2011-2018
    • Merlin, D.1    Steel, A.2    Gewirtz, A.T.3    Si-Tahar, M.4    Hediger, M.A.5    Madara, J.L.6
  • 21
    • 33847700163 scopus 로고    scopus 로고
    • Leptin transcriptionally enhances peptide transporter (hPepT1) expression and activity via the cAMP-response element-binding protein and Cdx2 transcription factors
    • Nduati V, Yan Y, Dalmasso G, Driss A, Sitaraman S, Merlin D. Leptin transcriptionally enhances peptide transporter (hPepT1) expression and activity via the cAMP-response element-binding protein and Cdx2 transcription factors. J Biol Chem 282: 1359-1373, 2007.
    • (2007) J Biol Chem , vol.282 , pp. 1359-1373
    • Nduati, V.1    Yan, Y.2    Dalmasso, G.3    Driss, A.4    Sitaraman, S.5    Merlin, D.6
  • 24
    • 33745594044 scopus 로고    scopus 로고
    • The gut flora as a forgotten organ
    • O'Hara AM, Shanahan F. The gut flora as a forgotten organ. EMBO Rep 7: 688-693, 2006.
    • (2006) EMBO Rep , vol.7 , pp. 688-693
    • O'Hara, A.M.1    Shanahan, F.2
  • 26
    • 0030593695 scopus 로고    scopus 로고
    • Immunolocalization and pharmacological relevance of oligopeptide transporter PepT1 in intestinal absorption of beta-lactam antibiotics
    • DOI 10.1016/0014-5793(96)00778-8
    • Sai Y, Tamai I, Sumikawa H, Hayashi K, Nakanishi T, Amano O, Numata M, Iseki S, Tsuji A. Immunolocalization and pharmacological relevance of oligopeptide transporter PepT1 in intestinal absorption of beta-lactam antibiotics. FEBS Lett 392: 25-29, 1996. (Pubitemid 26268325)
    • (1996) FEBS Letters , vol.392 , Issue.1 , pp. 25-29
    • Sai, Y.1    Tamai, I.2    Sumikawa, H.3    Hayashi, K.4    Nakanishi, T.5    Amano, O.6    Numata, M.7    Iseki, S.8    Tsuji, A.9
  • 27
    • 33646083226 scopus 로고    scopus 로고
    • The transcription factor Cdx2 regulates the intestine-specific expression of human peptide transporter 1 through functional interaction with Sp1
    • Shimakura J, Terada T, Shimada Y, Katsura T, Inui K. The transcription factor Cdx2 regulates the intestine-specific expression of human peptide transporter 1 through functional interaction with Sp1. Biochem Pharmacol 71: 1581-1588, 2006.
    • (2006) Biochem Pharmacol , vol.71 , pp. 1581-1588
    • Shimakura, J.1    Terada, T.2    Shimada, Y.3    Katsura, T.4    Inui, K.5
  • 29
    • 0031053682 scopus 로고    scopus 로고
    • Stoichiometry and pH dependence of the rabbit proton-dependent oligopeptide transporter PepT1
    • Steel A, Nussberger S, Romero MF, Boron WF, Boyd CA, Hediger MA. Stoichiometry and pH dependence of the rabbit proton-dependent oligopeptide transporter PepT1. J Physiol 498: 563-569, 1997.
    • (1997) J Physiol , vol.498 , pp. 563-569
    • Steel, A.1    Nussberger, S.2    Romero, M.F.3    Boron, W.F.4    Boyd, C.A.5    Hediger, M.A.6
  • 31
    • 0027281573 scopus 로고
    • + symport in intact human intestinal (Caco-2) epithelium: A novel method utilising continuous intracellular pH measurement
    • + symport in intact human intestinal (Caco-2) epithelium: a novel method utilising continuous intracellular pH measurement. Biochem Biophys Res Commun 194: 432-438, 1993.
    • (1993) Biochem Biophys Res Commun , vol.194 , pp. 432-438
    • Thwaites, D.T.1    Hirst, B.H.2    Simmons, N.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.