5-HT1A receptor-mediated inhibition of acetylcholine release from guinea pig myenteric plexus: Potential mechanisms

Neuropharmacology

Volumn 35, Issue 4, 1996, Pages 483-488

  Dietrich, C ^a   Kilbinger, H ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

5 HT1A receptor; Acetylcholine release; Forskolin; Myenteric plexus; Pertussis toxin; Protein kinase C

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; ACETYLCHOLINE; ADENYLATE CYCLASE TOXIN; AH 21 132; AH 21-132; BORDETELLA VIRULENCE FACTOR; CYCLIC AMP; FORSKOLIN; NAPHTHYRIDINE DERIVATIVE; PERTUSSIS TOXIN; PHORBOL DIBUTYRATE; PHOSPHODIESTERASE INHIBITOR; PROTEIN KINASE C; SEROTONIN AGONIST; SEROTONIN RECEPTOR; 6 (4 ACETAMIDOPHENYL) 1,2,3,4,4A,10B HEXAHYDRO 8,9 DIMETHOXY 2 METHYLBENZO[C][1,6]NAPHTHYRIDINE; PRESYNAPTIC RECEPTOR; SEROTONIN 1A RECEPTOR;

ANIMAL; ARTICLE; ENZYME ACTIVATION; FEMALE; GUINEA PIG; IN VITRO STUDY; MALE; METABOLISM; MYENTERIC PLEXUS; PHYSIOLOGY; SIGNAL TRANSDUCTION; ACETYLCHOLINE RELEASE; ANIMAL TISSUE; CHOLINERGIC NERVE; INTESTINE INNERVATION; NONHUMAN; PRIORITY JOURNAL;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ACETYLCHOLINE; ADENYLATE CYCLASE TOXIN; ANIMALS; CYCLIC AMP; ENZYME ACTIVATION; FEMALE; FORSKOLIN; GUINEA PIGS; MALE; MYENTERIC PLEXUS; NAPHTHYRIDINES; PERTUSSIS TOXIN; PHORBOL 12,13-DIBUTYRATE; PHOSPHODIESTERASE INHIBITORS; PROTEIN KINASE C; RECEPTORS, SEROTONIN; SEROTONIN AGONISTS; SIGNAL TRANSDUCTION; VIRULENCE FACTORS, BORDETELLA;

EID: 0029665567     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/0028-3908(95)00197-2     Document Type: Article

References (25)

1. B receptors in the same channels in hippocampus. Science 234: 1261-1265.
2. Ashendal C. L. (1985) The phorbol ester receptor: a phospholipid-regulated protein kinase. Biochim. biophys. Acta 822: 219-242.
3. 1A receptors in the dorsal raphe and hippocampus: II. Effect of pertussis and cholera toxins. J. Pharmacol. exp. Ther. 265: 16-23.
4. Böhm M., Brückner R., Neumann J., Schmitz W., Scholz H. and Sherbatty I. (1986) Role of guanine nucleotide-binding protein in the regulation by adenosine of cardiac potassium conductance and force of contraction. Evaluation with pertussis toxin. Naunyn-Schmiedeberg's Arch Pharmacol. 332: 403-405.
5. Christofi F. L. and Wood J. D. (1993) Presynaptic inhibition by adenosine-A1 receptors on guinea pig small intestinal myenteric neurons. Gastroenterology 104: 1420-1429.
6. Clarke D. E., Bond R. A., Charlton K. G. and Blue D. R. (1989) Pre-synaptic 5-HT receptors mediating inhibition of transmitter release from peripheral cholinergic and noradrenaergic nerves. In: Serotonin - Actions, Receptors, Pathophysiology (Mylecharane E. J., Angus J. A., de la Lande I. S. and Humphrey P. P. A., eds), pp. 48-55. Macmillan Press, London.
7. 1A-receptors and carbachol-stimulated phosphoinositide turnover in the rat hippocampus. J. Neurochem. 56: 1276-1285.
8. Colino A. and Halliwell J. V. (1987) Differential modulation of three seperate K-conductances in hippocampal CA1-neurones by serotonin. Nature 328: 73-77.
9. 1A receptor - an overview of recent advances. Neurochem. Res. 16: 1-10.
10. 1A receptors. Br. J Pharmacol. 86: 601P.
11. 1 receptors on myenteric and submucosal neurons. Am. J. Physiol. 255: G603-G611.
12. Hoyer D., Clarke D. E., Fozard J. R., Hartig P. R., Martin G. R., Mylecharane E. J., Saxena P. R. and Humphrey P. P. A. (1994): International union of pharmacology classification of receptors for 5-hydroxytryptamine (serotonin). Pharmacol. Rev. 46: 157-203.
13. Kilbinger H. and Pfeuffer-Friederich I. (1985) Two types of receptors for 5-hydroxytryptamine on the cholinergic nerves of the guinea-pig myenteric plexus. Br. J. Pharmacol. 85: 529-539.
14. 4 receptor stimulation on basal and electrically evoked release of acetylcholine from guinea-pig myenteric plexus. Naunyn-Schmiedeberg's Arch. Pharmacol. 345: 270-275.
15. Lux B. L. and Schulz R. (1986) Effect of cholera toxin and pertussis toxin on opiod tolerance and dependence in the guinea-pig myenteric plexus. J. Pharmacol. exp. Ther. 237: 995-1000.
16. Markstein R., Digges K., Marshall N. R. and Starke K. (1984) Forskolin and the release of noradrenaline in cerebrocortical slices. Naunyn-Schmiedeberg's Arch. Pharmacol. 325: 17-24.
17. 4 receptors mediate inhibition and facilitation of fast synaptic transmission in enteric neurones. Am. J. Physiol. 266: G230-G238.
18. 1A receptor. J. biol. Chem. 266: 14,747-14,753.
19. Seamon K. B. and Daly J. W. (1986) Forskolin: its biogical and chemical properties. In: Advances in Cyclic Nucleotide and Protein Phosphorylation Research, Vol. 20 (Greengard P. and Robison G. A., eds), pp. 1-150. Raven Press, New York.
20. Small R. C., Boyle J. P., Elliott K. R. F., Foster R. W. and Watt A. I. (1989) Inhibitory effects of AH 21-132 in guinea-pig isolated ileum and taenia caeci. Br. J. Pharmacol. 97: 1174-1181.
21. 1A receptors: anomalous effects with RS-30199-193. Br. J. Pharmacol. 104: 519-525.
22. Starke K., Göthert M. and Kilbinger H. (1989) Modulation of neurotransmitter release by presynaptic autoreceptors. Physiol. Rev. 69: 864-989.
23. Tanaka C. and Nishizuka Y. (1994) The protein kinase C family for neuronal signaling. A. Rev. Neurosci. 17: 551-567.
24. Tanaka C., Taniyama K. and Kusunoki M. (1984) A phorbol ester and A 23187 act synergistically to release acetylcholine from the guinea-pig ileum. FEBS Lett. 175: 165-169.
25. Vizi E. S. and Knoll J. (1976) The inhibitory effect of adenosine and related nucleotides on the release of acetylcholine. Neuroscience 1: 391-398.