Suppression of radiation-induced testicular germ cell apoptosis by 2,5-hexanedione pretreatment. II. Gene array analysis reveals adaptive changes in cell cycle and cell death pathways

Toxicological Sciences

Volumn 117, Issue 2, 2010, Pages 457-465

  Campion, Sarah N ^a   Houseman, E Andres ^b   Sandrof, Moses A ^a   Hensley, Janan B ^c   Sui, Yunxia ^b   Gaido, Kevin W ^c   Wu, Zhijin ^b   Boekelheide, Kim ^a  

^a BROWN UNIVERSITY   (United States)

^b BROWN UNIVERSITY   (United States)

^c HAMNER INSTITUTES FOR HEALTH SCIENCES   (United States)

Author keywords

2,5 hexanedione; Co exposure; Microarray; Testis; X radiation

Indexed keywords

ACETONYLACETONE; APOPTOSIS ENHANCING NUCLEASE; CASPASE 3; FAS ANTIGEN; FAS LIGAND; NUCLEASE; PROTEIN BCL 2; PROTEIN P53; PUMA PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL POPULATION; CELL TYPE; CONTROLLED STUDY; CYTOTOXICITY; GENE EXPRESSION; GENETIC ANALYSIS; GERM CELL; LASER CAPTURE MICRODISSECTION; MALE; MICROARRAY ANALYSIS; NONHUMAN; RADIATION EXPOSURE; RAT; REAL TIME POLYMERASE CHAIN REACTION; SEMINIFEROUS TUBULE; TESTIS; X RAY;

ANIMALS; APOPTOSIS; GENE EXPRESSION REGULATION; GENES, CDC; HEXANONES; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RADIATION-PROTECTIVE AGENTS; RATS; RATS, INBRED F344; SEMINIFEROUS TUBULES; SPERMATOZOA;

RATTUS;

EID: 77956929094     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfq204     Document Type: Article

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