Gene expression profiles in rainbow trout, onchorynchus mykiss, exposed to a simple chemical mixture

Toxicological Sciences

Volumn 102, Issue 1, 2008, Pages 42-60

  Hook, Sharon E ^a   Skillman, Ann D ^a   Gopalan, Banu ^b,c   Small, Jack A ^b   Schultz, Irvin R ^a  

^a BATTELLE MEMORIAL INSTITUTE   (United States)

^b PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

^c LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Chemical mixtures; Gene expression; Microarrays; Rainbow trout; Toxicokinetics

Indexed keywords

CHROMIUM; COMPLEMENTARY DNA; ENVIRONMENTAL CHEMICAL; ETHINYLESTRADIOL;

ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHEMICAL ANALYSIS; CLUSTER ANALYSIS; COMPUTER PROGRAM; CONTAMINATION; CONTROLLED STUDY; DOSIMETRY; DOWN REGULATION; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL IMPACT; FLUORESCENCE ANALYSIS; GENE CLUSTER; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GENE MUTATION; MICROARRAY ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; RAINBOW TROUT; SALMONID; TOXICOKINETICS; TRANSCRIPTOMICS;

ANIMALS; BODY BURDEN; CHROMIUM; CLUSTER ANALYSIS; DRUG INTERACTIONS; ENVIRONMENTAL MONITORING; ETHINYL ESTRADIOL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HYDROCARBONS, BROMINATED; LIVER; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; ONCORHYNCHUS MYKISS; PHENYL ETHERS; POLYMERASE CHAIN REACTION; REPRODUCIBILITY OF RESULTS; TIME FACTORS; WATER POLLUTANTS, CHEMICAL;

ONCORHYNCHUS MYKISS; SALMONIDAE;

EID: 39149119635     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfm293     Document Type: Article

References (56)

1. Altschul, S. F., Gish, W., Miller, W., Myers, E. W., and Lipman, D. J. (1990). Basic local alignment search tool. J. Mol. Biol. 215 403-410.
2. Amin, R. P., Hamadeh, H. K., Bushel, P. R., Bennett, L., Afshari, C. A., and Paules, R. S. (2002). Genomic interrogation of mechanism(s) underlying cellular responses to toxicants. Toxicology 181-182 555-563.
3. Ankley, G. T., Daston, G. P., Degitz, S. J., Denslow, N. D., Hoke, R. A., Kennedy, S. W., Miracle, A. L., Perkins. E. J, Snape, J., Tillitt, D. E., et al. (2006). Toxicogenomics in regulatory ecotoxicology. Environ. Sci. Technol. 102 (1), 42-60.
4. Arukwe, A., Kullman, S. W., and Hinton, D. E (2001). Differential biomarker and protein expressions in nonylphenol and estradiol-17β treated rainbow trout (Onchorynchus mykiss). Comp. Biochem. Phys. C 129, 1-10.
5. Bartosiewicz, M., Penn, S., and Buckpitt, A. (2001). Applications of gene arrays in environmental toxicology, fingerprints of gene regulation associated with cadmium chloride, benzo(a)pyrene and trichloroethylene. Environ. Health Perspect. 109, 71-74.
6. Brazma, A., Hingamp, P., Quackenbush, J., Sherlock, G., Spellman, P., Stoeckert, C., Aach, J., Ansorge, W., Ball, C. A., Causton, H. C., et al. (2001). Minimum information about a microarray experiment (MIAME) - Toward standards for microarray data. Nat. Rev. Genet. 29, 365-371.
7. Butte, A. (2002). The use and analysis of microarray data. Nat. Rev. Genet. 1, 951-960.
8. Chapman, L. M., Roling, J. A., Bingham, L. K., Herald, M. R., and Baldwin, W. S. (2004). Constraction of a subtractive library from hexavalent chromium treated winter flounder (Pseduopleuronectes americanus) reveals alterations in non-selenium glutathione peroxidases. Aquat. Toxicol. 67, 181-194.
9. Claverie, J.-M. (1999). Computational methods for the identification of differential and co-ordinated gene expression. Hum. Mol. Genet. 8, 1821-1832.
10. Donnelly, K. C., Lingenfelter, R., Cizmas, L., Falahatpisheh, M. H., Qian, Y., Tang, Y., Garcia, S., Ramos, K., Tiffany-Castiglioni, E., and Mumtaz, M. M., (2004). Toxicity assessment of complex mixtures remains a goal. Environ. Toxicol. Pharmacol. 18, 135-141.
11. Draghici, S. (2003). Data Analysis Tools for DNA Microarrays. Chapman & Hall, London.
12. Eide, I., Neverdal, G., Thorvaldsen, B., Arneberg, R., Grung, B., and Kvalheim, O. M. (2006). Toxicological evaluator of complex mixtures: Fingerprinting and multivariate analysis. Environ. Toxicol Pharmacol. 18, 127-133.
13. Farag, A. M., May, F., Marty, G. D., Easton, M., Harper, D.D., Little, E. E., and Cleveland, L. (2006). The effect of chronic chromium exposure on the health of Chinook salmon (Ohcorhynchus tshawytscha). Aquat. Toxicol. 76, 246-257.
14. Finne, E. F., Cooper, G. A., Koop, B. F., Hyllaud, K., and Tollefsen, K. E. (2007). Toxicogenomic responses in rainbow trout (Onchorynchus mykiss) hepatocytes exposed to model chemicals and a synthetic mixture. Aquat. Toxicol. 81, 292-303.
15. Folt, C. L., Chen, C. Y., Moore, M. V., and Burnaford, J. (1999). Synergism and antagonism among multiple stressors. Limnol Ocean 44, 864-877.
16. Gibaldi, M., and Perrier, D. (1982). Pharmacokinetics. Marcel Dekker, Inc. New York. p.487.
17. Hook, S. E., Skillman, A. D., Small, J. A., and Schultz, I. R. (2006a). Gene expression patterns in rainbow trout, Onchorynchus mykiss, exposed to a suite of model toxicants. Aquat. Toxicol. 77, 372-385.
18. Hook, S. E., Skillman, A. D., Small, J. A., and Schultz, I. R. (2006b). Dose response relationships in gene expression profiles in rainbow trout, Onchorynchus mykiss exposed to ethinylestradiol. Mar. Environ. Res. 62, S151-154.
19. Hook, S. E., Skillman, A. D., Small, J. A., and Schultz, I. R. (2007). Temporal changes in gene expression in rainbow trout exposed to ethynyl estradiol. Comp. Biochem. Phys. 145, 73-85.
20. Koskinen, H., Pehkonen, P., Vehniainen, E., Krasnov, A., Rexroad, C., Afanasyev, S., Molsa, H., and Oikari, A. (2004). Response of rainbow trout transcriptome to model chemical contaminants. Biochem. Biophys. Res. Commun. 320, 745-753.
21. Larkin, P., Folmar, L. C., Hemmer, M. C., Poston, A. J., and Denslow, N. D. (2003b). Expression profiling of estrogenic compounds using a sheepshead minnow cDNA Macroarray. Environ. Health Perspect. 111, 839-846.
22. Larkin, P., Folmar, L. C., Hemmer, M. J., Poston, A. J., Lee, H. S., and Denslow, N. D. (2002). Array technology as a tool to monitor exposure to fish xenoestrogens. Mar. Environ. Res. 54, 395-399.
23. Larkin, P., Sabo-Attwood, T., Kelso, J., and Denslow, N. D. (2003a). Analysis of gene expression profiles in largemouth bass exposed to 17-B-estradiol and to anthroprogenic contaminants that behave as estrogens. Ecotoxicology 12, 463-468.
24. Le Roux, M. G., Theze, N., Wolff, J., and Le Pennec, J. P. (1993). Organization of a rainbow trout estrogen receptor gene. Biochhn. Biophys. Acta 1172, 226-230.
25. Lopez, F., Rougemont, J., Loriod, B., Bourgeois, A., Loi, L., Bertucci, F., Hingamp, P., Houlgatte, R., and Granjeaud, S. (2004). Feature extraction and signal processing for nylon DNA microarrays. BMC Genomics 5, 38.
26. Monteverdi, G. H., and Di Giulio, R. T. (2000). In vitro and in vivo association of 2,3,7,8-tetrachlorodibenzo-p-dioxin and benzo[a]pyrene with the yolk-precursor protein vitellogenin. Environ. Toxicol. Chem. 19, 2502-2511.
27. Moreira, P. I., Custodio, J. B. A., Nunes, E., Moreno, A., Seica, R., Oliveira, C. R., and Santos, M. S. (2007). Estradiol affects liver mitochondrial function in ovariectomized and tamoxifen-treated ovariectomized female rats. Toxicol. Appl. Pharmacol. 221, 102-110.
28. Morel, F., Rauch, C., Petit, E., Piton, A., Theret, N., Coles, B., and Guillouzo, A. (2004). Gene and protein characterization of the human glutathione S-transferase kappa and evidence for a peroxisomal localization. J. Biol. Chem. 279, 16246-16253.
29. Muirhead, E. K., Skillman, A. D., Hook, S., and Schultz, I. R. (2006). Oral exposure of PBDE-47 in fish: Toxicokinetics and reproductive effects in Japanese medaka (Oryzias latipes) and fathead minnows (Pimephales promelas). Environ. Sci. Technol. 40, 523-528.
30. Nagler, J. J., Cavileer, T., Sullivan, J., Cyr, D. G., and Rexroad, C. (2007). The complete nuclear estrogen receptor family in the rainbow trout: Discovery of the novel ER alpha 2 and both ER beta isoforms. Gene 392, 164-473.
31. Oleksiak, M. F., Churchill, G. A., and Crawford, D. L. (2002). Variation in gene expression within and among natural populations. Nat. Genet. 32, 261-266.
32. O'Lone, R., Knorr, K., Jaffe, I. Z., Schaffer, M. E., Martini, P. G. V., Karas, R. H., Bienkowska, J., Mendelsohn, M. E., and Hansen, U. (2007). Estrogen receptors alpha and beta mediate distinct pathways of vascular gene expression, including genes involved in mitochondrial electron transport and generation of reactive oxygen species. Mol. Endocrinol. 21, 1281-1296.
33. Pakdel, F., Metivier, R., Flouriot, G., and Valotaire, Y. (2000). Two different estrogen receptor (ER) isciforms with different estrogen dependencies are generated from the trout ER gene. Endocrinology. 141, 571-580.
34. Patton, G., Dauble, D., and McKinstry, C. (2007). Evaluation of early life stage fall chinook salmon exposed to hexavalent chromium from a contaminated groundwater source. Environ. Monit. Assess. 133 285-295.
35. Posse, C., Sanfilippo, A., Gopalan, B., Riensche, R., Beagley, N., and Baddeley, B. (2006). Cross-Ontological Analytics: Combining associative and hierarchical relations in the Gene Ontologies to assess gene product similarity. Proceedings of International Workshop on Bioinformatics Research and Applications. Reading, U.K.
36. Riensche, R. M., Baddeley, B. L., Sanfilippo, A., Posse, C., and Gopalan, B. (2007). XOA: Web-Enabled Cross-Ontological Analytics, IEEE International Workshop on Service Oriented Technologies for Biological Datababes and Tools, July 2007. Utah, USA.
37. Rise, M. L., Jones,. S. R. M., Brown, G. D., von Schalburg, K. R., Davidson, W. S., and Koop, B. F. (2004b). Microarray analyses identify molecular biomarkers of Atlantic salmon macrophage and hematopoietic kidney response to Piscirickettsia, salmonis infection. Physiol. Genomics 20, 31-35.
38. Rise, M. L., von Schalburg, K. R., Brown, G. D., Mawer. M. A., Devlin, R. H., Kuipers, N., Busby, M., Beetz-Sargent, M., Alberto, R., Gibbs, A. R., et al. (2004a). Development and application of a Salmonind EST database and cDNA microarray: Data mining aiid interspecific hybridization characteristics. Genome Res. 14, 478-490.
39. Sabo-Atwood, T., Kroll, K. J., and Denslow, N. D. (2004). Differential expression of largemouth bass (Micropterus salmoides) estrogen receptor isotypes by alpha, beta and gamma by estradiol. Mol. Cell. Endocrinol. 218, 107-118.
40. Sanfilippo, A., Posse, C., Gopalan, B., Tratz, S., and Gregory, M. (2007). Combining hierarchical and associative gene ontology relations with textual evidence in estimating gone and gene product similarity. IEEE Trans. NanoBiosci. 6(1).
41. Schultz, I. R., and Hayton, W. L. (1997). Influence of body fat on trifluralin toxicokinetics in rainbow trout (Oncorhynchus mykiss). Environ. Toxicol. Chem. 16, 997-1001.
42. Schultz, I. R., Orner, G., Merdenik, J. L., and Skillman, A. (2001). Dose-response relationships and pharmacokinetics of vitellogenin in rainbow trout after intravascular administration of 17alpha-ethynylestradiol. Aquat. Toxicol. 51, 305-318.
43. Schultz, I. R., Skillman, A., Nicolas, J. M., Cyr, D. G., and Nagler, J. J. (2003). Short-term exposure to 17 alpha-ethynylestradiol decreases the fertility of sexually maturing male rainbow trout. (Oncorhynchus mykiss). Enviroin. Toxicol. Chem. 22, 1272-1280.
44. Skillman, A. D., Nagler, J. J., Hook S. E., Small, J. A., and Schultz, I. R. (2006). Dynamics of ethynylestradiol exposure in rainbow trout ( Oncorhynchus mykiss): Absorption, tissue distribution and hepatic gene expression patterns. Environ. Toxicol. Chem. 25, 2297-3005:
45. Soetaert, A., Moens, L. N., Van de Ven K., Van Leemput, K., Naudts, B., Blust, R., and De Coen, W. M. (2006) Molecular impact of propiconazole on Daphnia magna using a reproduction-related cDNA array. Comp. Biochem. Phys. C 142, 66-76.
46. Tagliari, K. C., Vargas, V. M. F., Zimiani, K., and Cecchini, R. (2004). Oxidative stress damage in the liver of fish and rats receiving an intraperitoneal injection of hexavalent chromium as evaluated by chemiluminescence. Environ. Toxicol. Pharmacol. 17(3), 149-157.
47. Van Der Putte, I.; Lubbers, I., and Kolar, Z. (1980). Effect of pH on uptake, tissue distribution and retention of hexavalent chromium insrainbow trout (Salmo gairdneri). Aquat. Toxicol. 1(1), 3-18.
48. Venier, P., De Pitta, C., Pallavicini, A., Marsano, F., Varotto, L., Romuali, C., Dondero, F., Viarengo, A., and Lanfranchi, G. (2006). Development of mussel mRNA profiling: Can gene expression trends reveal coastal water pollution? Mutat. Res. 602, 121-134.
49. von Schalburg, K. R., Rise, M. L., Brown, G. D., Davidson, W. S., and Koop, B. F. (2005a). A comprehensive survey of the genes involved in maturation and development of the rainbow trout ovary. Biol. Reprod. 72, 687-99.
50. von Schalburg, K. R., Rise, M. L., Cooper, G. A., Brown, G. D., Gibbs, A. R., Nelson, C. C., Davidson, W. S., and Koop, B. F. (2005b). Fish and chips: Various methodologies demonstrate utility of a 16,006-gene salmonid microarray. BMC Genomics Sep 15, 6-126.
51. Williams, T. D., Gensberg, K., Minchin, S. D., and Chipman, J. K. (2003). A DNA expression array to detect toxic strew response in European flounder (Platichtys flesus). Aquat. Toxicol. 65, 141-157.
52. Williams, T. D., Diab, A. M., George, S. G., Godfrey, R. E., Sabine, V., Conesa, A., Minchin, S. D., Watts, P. C., and Chipman, J. K. (2006). Development of the GENIPOL European Flounder (Platichthys flesus) microarray and determination of temporal transcriptional responses to cadmium at low dose. Environ. Sci. Technol. 40, 6479-6488.
53. Wintz, H., Yoo, L. J., Longuinov, A., Wul Y. Y., Steevens, J. A., Holland, R. D., Beger, R. D., Perkins, E. J., Hughes, O., and Valpe, C. D. (2006). Gene expressiorr profiles in fathead minnow exposed to 2,4-DNT: Correlation with toxicity in mammals. Toxicol. Sci. 94 71-82.
54. Yamaoka, K., Nakagawa, T., and Uno, T. (1978). Statistical moments in pharmacokinetics. J Pharmacokinet Biopharm 6, 587-558.
55. Yang, R. S. H., El-Masri, H. A., Thomas, R. S., Dobrev, I.D., Dennison, J. E., Jr, Bae, D.-S., Campain, J. A., Liao, K. H., Reisfeld, B., Andersen, M. E., et al. (2004). Chemical mixture toxicology: From descriptive to mechanistic, and going on to in silicio toxicology. Environ. Toxicol. Pharmacol. 18, 65-81.
56. Young, W. P., Wheeler, P. A., Fields, R. D., and Thorgaard, G. H. (1996). DNA fingerprinting confirms isogenicity of androgenetically-derived rainbow trout lines. J. Hered. 87, 77-81.