Lysophosphatidic acid stimulates gastric cancer cell proliferation via ERK1-dependent upregulation of sphingosine kinase 1 transcription

FEBS Letters

Volumn 584, Issue 18, 2010, Pages 4077-4082

  Ramachandran, Subramaniam ^a   Shida, Dai ^a   Nagahashi, Masayuki ^a   Fang, Xianjun ^a,b   Milstien, Sheldon ^a   Takabe, Kazuaki ^a,b   Spiegel, Sarah ^a,b  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

Gastric cancer; Lysophosphatidic acid; Proliferation; Sphingosine kinase

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN BETA; EPIDERMAL GROWTH FACTOR RECEPTOR; LYSOPHOSPHATIDIC ACID; LYSOPHOSPHATIDIC ACID RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE B; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE KINASE 1; STRESS ACTIVATED PROTEIN KINASE; CEBPB PROTEIN, HUMAN; LYSOPHOSPHOLIPID; PHOSPHOTRANSFERASE; PROTEIN KINASE INHIBITOR; SPHINGOSINE KINASE;

ARTICLE; CANCER CELL; CELL PROLIFERATION; CELL STRAIN; CELL STRAIN MKN1; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INDUCTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; STOMACH CANCER; TRANSCRIPTION REGULATION; ANTAGONISTS AND INHIBITORS; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; PATHOLOGY; STOMACH TUMOR; TRANSCRIPTION INITIATION; TUMOR CELL LINE; UPREGULATION;

CCAAT-ENHANCER-BINDING PROTEIN-BETA; CELL LINE, TUMOR; CELL PROLIFERATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LYSOPHOSPHOLIPIDS; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTEIN KINASE INHIBITORS; STOMACH NEOPLASMS; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION; UP-REGULATION;

EID: 77956918126     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2010.08.035     Document Type: Article

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