Do antioxidant micronutrients protect against the development and progression of knee osteoarthritis?

Arthritis and Rheumatism

Volumn 39, Issue 4, 1996, Pages 648-656

  McAlindon, Timothy E ^a   Jacques, Paul ^b   Zhang, Yuqing ^a   Hannan, Marian T ^a   Aliabadi, Piran ^c   Weissman, Barbara ^c   Rush, David ^b   Levy, Daniel ^d   Felson, David T ^a  

^a BOSTON UNIVERSITY MEDICAL CENTER   (United States)

^b TUFTS UNIVERSITY   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d FRAMINGHAM HEART STUDY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; BETA CAROTENE; FOLIC ACID; NICOTINIC ACID; PYRIDOXINE; REACTIVE OXYGEN METABOLITE; THIAMINE;

ADULT; AGED; ANTIOXIDANT ACTIVITY; ARTICLE; CARTILAGE DEGENERATION; DIET SUPPLEMENTATION; DIETARY INTAKE; DISEASE CONTROL; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; KNEE OSTEOARTHRITIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RISK ASSESSMENT; SCORING SYSTEM;

AGED; ANTIOXIDANTS; ASCORBIC ACID; BETA CAROTENE; CAROTENOIDS; COHORT STUDIES; DISEASE PROGRESSION; FEMALE; FOOD HABITS; HUMANS; INCIDENCE; KNEE JOINT; MALE; MICRONUTRIENTS; OSTEOARTHRITIS; RETROSPECTIVE STUDIES; VITAMIN E;

EID: 0029917748     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.1780390417     Document Type: Article

References (38)

1. Ames BN, Shigenaga MK, Hagen TM: Oxidants, antioxidants and the degenerative diseases of aging. Proc Natl Acad Sci USA 90:7915-7922, 1993
2. Frei B: Reactive oxygen species and antioxidant vitamins: mechanisms of action. Am J Med 97 (suppl 3A):5S-13S, 1994
3. Jacques PF, Chylack LT, Taylor A: Relationships between natural antioxidants and cataract formation. In, Natural Antioxidants in Human Health and Disease. Edited by B Frei. San Diego, CA, Academic Press, 1994
4. Gaziano JM: Antioxidant vitamins and coronary artery disease risk. Am J Med 97 (suppl 3A):18S-21S, 1994
5. Hennekens CH: Antioxidant vitamins and cancer. Am J Med 97 (suppl 3A):2S-4S, 1994
6. Henrotin Y, Deby-Dupont G, Deby C, Franchimont P, Emerit I: Active oxygen species, articular inflammation, and cartilage damage. EXS 62:308-322, 1992
7. Blake DR, Unsworth J, Outhwaite JM, Morris CJ, Merry P, Kido BL, Ballard R, Gray L, Lunec J: Hypoxic-reperfusion injury in the inflamed human. Lancet ii:290-293, 1989
8. Mandell BF, Lipani J: Refractory OA: differential diagnosis and treatment. Rheum Dis Clin North Am 21:163-178, 1995
9. Briviba K, Seis H: Non-enzymatic antioxidant defense systems. In, Natural Antioxidants in Human Health and Disease. Edited by B Frei. San Diego, CA, Academic Press, 1994
10. Hankinson SE, Stampfer MJ, Seddon JM, Colditz GA, Rosner B, Speizer FE, Willett WC: Nutrient intake and cataract extraction in women: a prospective study. BMJ 305:335-339, 1992
11. Jacques PF, Chylack LT: Epidemiological evidence of a role for the antioxidant vitamins and carotenoids in cataract prevention. Am J Clin Nutr 53:352S-355S, 1991
12. Manson JE, Stampfer MJ, Willett WC: A prospective study of antioxidant vitamins and incidence of coronary artery disease in women (abstract). Circulation 84 (suppl II):2168, 1991
13. Rimm EB, Stampfer MJ, Ascherio A, Giovannucci EL, Colditz GA, Willett WC: Vitamin E supplementation and risk of coronary heart disease among men. N Engl J Med 328:1450-1456, 1993
14. Schwartz ER, Leveille C, Oh WH: Experimentally induced osteoarthritis in guinea pigs: effect of surgical procedure and dietary intake of vitamin C. Lab Anim Sci 31:683-687, 1981
15. Meacock SCR, Bodmer JL, Billingham MEJ: Experimental OA in guinea pigs. J Exp Pathol 71:279-293, 1990
16. Felson DT: Osteoarthritis. Rheum Dis Clin North Am 16:499-512, 1990
17. McAlindon T, Dieppe P: The medical management of osteoarthritis of the knee: an inflammatory issue? Br J Rhematol 29:471-473, 1990
18. Felson DT, Zhang Y, Hannan MT, Naimark A, Weissman B, Aliabadi P, Levy D: The incidence and natural history of knee osteoarthritis in the elderly: the Framingham Osteoarthritis Study. Arthritis Rheum 38:1500-1505, 1995
19. Kellgren JH, Lawrence JS: The Epidemiology of Chronic Rheumatism: Atlas of Standard Radiographs. Vol. 2. Oxford, Blackwell Scientific, 1963
20. Spector TD, Hochberg MC: Methodological problems in the epidemiological study of osteoarthritis. Ann Rheum Dis 53:143-146, 1994
21. Reproducibility and validity of food frequency questionnaires. In, Nutritional Epidemiology. Monographs in Epidemiology and Biostatistics. Vol. 15. Edited by W Willett. New York, Oxford University Press, 1990
22. Rimm EB, Giovannucci EL, Stampfer MJ, Colditz GA, Litin LB, Willett WC: Reproducibility and validity of an expanded self-administered semi-quantitative food frequency questionnaire among male health professionals. Am J Epidemiol 135: 1114-1126, 1992
23. Salvini S, Hunter DJ, Sampson L, Colditz GA, Stampfer MJ, Rosner B, Willett WC: Food-based validation of a dietary questionnaire: the effects of week-to-week variation in food consumption. Int J Epidemiol 18:858-867, 1989
24. Jacques PF, Sulsky SI, Sadowski JA, Phillips JCC, Rush D, Willett WC: Comparison of micronutrient intake measured by a dietary questionnaire and biochemical indicators of micronutrient status. Am J Clin Nutr 57:182-189, 1993
25. Ascherio A, Stampfer MJ, Colditz GA, Rimm EB, Litin L, Willett WC: Correlations of vitamin A and E intakes with plasma concentrations of carotenoids and tocopherols among American men and women. J Nutr 122:1792-1801, 1992
26. Willett WC: Implications of total energy intake for epidemiologic analyses. In, Nutritional Epidemiology. Monographs in Epidemiology and Biostatistics. Vol. 15. Edited by W Willett. New York, Oxford University Press, 1990
27. Kannel WB, Sorlie PD: Some health benefits of physical activity: the Framingham Study. Arch Intern Med 139:857-861, 1979
28. Hannan MT, Felson DT, Anderson JJ, Naimark A: Habitual physical activity is not associated with knee osteoarthritis: the Framingham Study. J Rheumatol 20:704-709, 1993
29. Grant MD, Piotrowski ZH, Chappell R: Self-reported health and survival in the Longitudinal Study of Aging 3984-1986. J Clin Epidemiol 48:375-387, 1995
30. Liang KY, Zeger SL: Longitudinal data analysis using generalized linear models. Biometrika 73:13-22, 1986
31. Altman RD, Fries JF, Bloch DA, Carstens J, Cooke TD, Genant H, Gofton P, Groth H, McShane DJ, Murphy WA, Sharp JT, Spitz P, Williams CA, Wolfe F: Radiologic assessment of progression in osteoarthritis. Arthritis Rheum 30:1214-1225, 1987
32. Schumacher HR Jr: Synovial inflammation, crystals and osteoarthritis. J Rheumatol 22: (suppl 43):101-103, 1995
33. McAlindon TE, Hannan MT, Naimark A, Weissman B, Felson DT: Comparison of risk factors for patello-femoral and tibiofemoral osteoarthritis (abstract). Arthritis Rheum 37 (suppl 9): S370, 1994
34. Peterkofsky B: Ascorbate requirement for hydroxylation and secretion of procollagen: relationship to inhibition of collagen synthesis in scurvy. Am J Clin Nutr 54:1135S-1140S, 1991
35. Peterkofsky B, Palka J, Wilson S, Takeda K, Shah V: Elevated activity of low molecular weight insulin-like growth factor binding proteins in sera of vitamin C deficient and fasted guinea pigs. Endocrinology 128:1769-1779, 1991
36. Poole C: Multiple comparisons? No problem! Epidemiology 2:241-243, 1991
37. Schwartz ER, Adam L: Effect of ascorbic acid on arylsulfatase activities and sulfated proteoglycan metabolism in chonrocyte cultures. J Clin Invest 60:96-106, 1977
38. Spanheimer RG, Bird TA, Peterkofsky B: Regulation of collagen synthesis and mRNA levels in articular cartilage of scorbutic guinea pigs. Arch Biochem Biophys 246:33-41, 1986