Expression of early and late differentiation markers (proliferating cell nuclear antigen, syndecan-3, annexin VI, and alkaline phosphatase) by human osteoarthritic chondrocytes

American Journal of Pathology

Volumn 159, Issue 5, 2001, Pages 1777-1783

  Pfander, David ^a   Swoboda, Bernd ^a   Kirsch, Thorsten ^b  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; CALPHOBINDIN II; CYCLINE; SYNDECAN;

ARTICLE; CARTILAGE CELL; CELL DIFFERENTIATION; CONTROLLED STUDY; DISEASE COURSE; EXTRACELLULAR MATRIX; GROWTH PLATE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; OSTEOARTHRITIS; PRIORITY JOURNAL;

EID: 0035153590     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)63024-6     Document Type: Article

References (40)

1. Osteoarthritic Disorders
2. Discoordinate gene expression of aggrecan and type II collagen in experimental osteo arthritis
3. Changes in messenger RNA and protein levels of proteoglycans and link protein in human osteoarthritic cartilage samples
4. Type X collagen synthesis in human osteoarthritic cartilage. Indication of chondrocyte hypertrophy
5. Distribution of type X collagen mRNA in normal and osteoarthritic human cartilage
6. Expression of anchorin CII (cartilage annexin V) in human young, normal adult, and osteoarthritic cartilage
7. Activation of annexin II and V expression, terminal differentiation, mineralization and apoptosis in human osteoarthritic cartilage
8. Differentiation, modulation and dedifferentiation of chondrocytes
9. Phosphatases of epiphyseal cartilage studied by electron microscopic cytochemical methods
10. Differences in collagen metabolism between normal and osteoarthritic human articular cartilage
11. Altered expression of collagen phenotype in osteoarthrosis
12. Independent expression of fibril-forming collagens I, II, and III in chondrocytes of human osteoarthritic cartilage
13. Syndecan-3 and the control of chondrocyte proliferation during endochondral ossification
14. Biology of syndecans: A family of heparan sulfate proteoglycans
15. 2+ regulated phospholipid-binding proteins
16. Similarity in calcium channel activity of annexin v and matrix vesicles in planar lipid bilayers
17. The roles of annexins and types II and X collagen in matrix vesicle-mediated mineralization of growth plate cartilage
18. Molecular biology of matrix vesicles
19. Regulatory roles of zinc in matrix vesicle-mediated mineralization of growth plate cartilage
20. In vivo modulation of proliferating cell nuclear antigen in growth plate chondrocytes from normal, hypophysectomized, and growth hormone-treated hypophysectomized rats: A comparative immunohistochemical study with image analysis
21. Biochemical and metabolic abnormalities in articular cartilage from osteoarthritic human hips. II. Correlation of morphology and metabolic data
22. Expression of thrombospondin-1 and its receptor CD36 in human osteoarthritic cartilage
23. Characterization of chicken syndecan-3 as a heparan sulfate proteoglycan and its expression during embryogenesis
24. Isolation and preliminary, characterization of a monoclonal antibody that interacts preferentially with the liver isoenzyme of human alkaline phosphatase
25. Association of matrix acid and alkaline phosphatases with mineralization of cartilage and endochondral bone
26. Analysis of proliferative grade using anti-PCNA cyclin monoclonal antibodies in fixed, embedded tissues
27. Proliferating cell nuclear antigen (PCNA) immunolocalization in paraffin sections: An index of cell proliferation with evidence of deregulated expression in some neoplasms
28. Chondrocyte-derived apoptotic bodies and calcification of articular cartilage
29. Matrix vesicle enzymes in human osteoarthritis
30. Human osteoarthritic cartilage matrix vesicles generate both calcium pyrophosphate dihydrate and apatite in vitro
31. Identity of the proliferating cell nuclear antigen and cyclin
32. Blundell PA: Cyclin/PCNA is the auxiliary protein of DNA polymerase delta
33. Localization and quantification of proliferating cells during rat fracture repair: Detection of proliferating cell nuclear antigen by immunohistochemistry
34. Ultrastructural study of chondrocytes from fibrillated and non-fibrillated human osteoarthritic cartilage
35. Mitosis in human articular osteoarthritic cartilage
36. Osteoarthritis chondrocytes die by apoptosis-a possible pathway for osteoarthritis pathology
37. Ultrastructural localisation of alkaline phosphatase activity in osteoarthritic human articular cartilage
38. Chondrocyte differentiation in human osteoarthritis: Expression of osteocalcin in normal and osteoarthritic cartilage and bone
39. Osteopontin is expressed by adult human osteoarthritic chondrocytes: Protein and mRNA analysis of normal and osteoarthritic cartilage