C-reactive protein (CRP) up-regulates expression of receptor for advanced glycation end products (RAGE) and its inflammatory ligand EN-RAGE in THP-1 cells: Inhibitory effects of atorvastatin

International Journal of Cardiology

Volumn 142, Issue 3, 2010, Pages 273-278

  Mahajan, Nitin ^a   Bahl, Ajay ^a   Dhawan, Veena ^a  

^a POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

Atorvastatin; C reactive protein; EN RAGE; MAPK; RAGE

Indexed keywords

ATORVASTATIN; BINDING PROTEIN; C REACTIVE PROTEIN; EN RAGE BINDING PROTEIN; LIGAND; MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; RECEPTOR FOR ADVANCED GLYCATION END PRODUCT; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; UNCLASSIFIED DRUG; ADVANCED GLYCATION END PRODUCT; ADVANCED GLYCOSYLATION END-PRODUCT RECEPTOR; FC RECEPTOR; HEPTANOIC ACID DERIVATIVE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IMMUNOGLOBULIN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN S 100; PYRROLE DERIVATIVE; S100A12 PROTEIN, HUMAN;

ARTICLE; CELL LINE; CELL PROLIFERATION; CELL VIABILITY; DRUG EFFECT; GENE EXPRESSION; HUMAN; HUMAN CELL; MODULATION; MONOCYTE; PRIORITY JOURNAL; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; CELL DIVISION; CELL SURVIVAL; CYTOLOGY; DRUG EFFECTS; GENETICS; IMMUNOLOGY; METABOLISM; TUMOR CELL LINE; UPREGULATION;

C-REACTIVE PROTEIN; CELL DIVISION; CELL LINE, TUMOR; CELL SURVIVAL; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION; GLYCOSYLATION END PRODUCTS, ADVANCED; HEPTANOIC ACIDS; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE SIGNALING SYSTEM; MONOCYTES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PYRROLES; RECEPTORS, IGG; RECEPTORS, IMMUNOLOGIC; S100 PROTEINS; UP-REGULATION;

EID: 77956870724     PISSN: 01675273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijcard.2009.01.008     Document Type: Article

References (41)

1. E. Paffen, and M.P.K. de Maat C-reactive protein in atherosclerosis: a causal factor? Cardiovasc Res 71 2006 30 39
2. J. Cermak, N.S. Key, and R.R. Bach, et al. C-reactive protein induces human peripheral blood monocytes to synthesize tissue factor Blood 82 1993 513 520
3. T.N. Williams, C.X. Zhang, and B.A. Game, et al. C-reactive protein stimulates MMP-1 expression in U937 histocytes through Fc[gamma]RII and extracellular signal-regulated kinase pathway: an implication of CRP involvement in plaque destabilization Arterioscler Thromb Vasc Biol 24 2004 61 66
4. A. Naoki, T. Osanai, and T. Fujiwara, et al. C-reactive protein-induced up-regulation of extracellular matrix metalloproteinase inducer in macrophages: inhibitory effect of fluvastatin Life Sci 78 2006 1021 1028
5. Y. Zhong, S.H. Li, and S.M. Liu, et al. Expression in human endothelial cells C-reactive protein upregulates receptor for advanced glycation end products Hypertension 48 2006 504 511
6. C.H. Wang, S.H. Li, and R.D. Weisel, et al. C-reactive protein up-regulates angiotensin type 1 receptors in vascular smooth muscle Circulation 107 2003 1783 1790
7. K. Herold, B. Moser, and Y. Chen, et al. Receptor for advanced glycation end products (RAGE) in a dash to the rescue: inflammatory signals gone awry in the primal response to stress J Leukoc Biol 82 2007 204 212
8. H. Koyama, H. Yamamoto, and Y. Nishizawa RAGE and soluble RAGE: potential therapeutic targets for cardiovascular diseases Mol Med 13 2007 625 635
9. G. Basta Receptor for advanced glycation end products and atherosclerosis: from basic mechanisms to clinical implications Atherosclerosis 196 2008 9 21
10. M.A. Hofmann, S. Drury, and C. Fu, et al. RAGE mediates a novel pro-inflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides Cell 97 1999 889 901
11. J. Pietzsch, and S. Hoppmann Human S100A12: a novel key player in inflammation? Amino Acids 2008 10.1007/s00726-008-0097-7
12. Z. Yang, T. Tao, and M.J. Raftery, et al. Inflammatory properties of the human S100 protein S100A12 J Leukoc Biol 69 2001 986 994
13. S. Kumar, J. Boehm, and J.C. Lee p38 MAPKs: key signalling molecules as therapeutic targets for inflammatory diseases Nat Rev Drug Discov 2 2003 717 726
14. S.P. Ballou, and G. Lozanski Induction of inflammatory cytokine release from cultured human monocytes by C-reactive protein Cytokine 4 1992 361 368
15. T. Force, C.M. Pombo, and A.J. Avruch, et al. Stress activated protein kinases in cardiovascular disease Circ Res 78 1996 947 953
16. S. Wassmann, U. Laufs, and K. Muller, et al. Cellular antioxidant effects of atorvastatin in vitro and in vivo Arterioscler Thromb Vasc Biol 22 2002 300 305
17. W. Palinski, and S. Tsimikas Immunomodulatory effects of statins: mechanisms and potential impact on arteriosclerosis J Am Soc Nephrol 13 2002 1673 1681
18. R. Paoletti, C. Bolego, and A. Cignarella Lipid and non-lipid effects of statins Hand Exp Pharm 170 2005 359 382
19. Heart Protection Study Collaborative Group MRC/BHF heart protection study of cholesterol lowering with simvastatin in 20536 high risk individuals: a randomised placebo controlled trial Lancet 360 2002 7 22
20. Y. Fukumoto, P. Libby, and E. Rabkin, et al. Statins alter smooth muscle cell accumulation and collagen content in established atheroma of watanabe heritable hyperlipidemic rabbits Circulation 103 2001 993 999
21. N. Mahajan, V. Dhawan, G. Sharma, S. Jain, and D. Kaul Induction of inflammatory gene expression by THP-1 macrophages cultured in normocholesterolaemic hypertensive sera and modulatory effects of green tea polyphenols J Hum Hypertens 22 2008 141 143
22. R. Ross Atherosclerosis-an inflammatory disease NEJM 340 1999 115 126
23. S. Verma, S. Devaraj, and I. Jialal Is C-reactive protein an innocent bystander or proatherogenic culprit? C-reactive protein promotes atherothrombosis Circulation 113 2006 2135 2150
24. G. Basta, A.M. Sironi, and G. Lazzerini, et al. Circulating soluble receptor for advanced glycation end products is inversely associated with glycemic control and S100A12 protein J Clin Endocrinol Metab 91 2006 4628 4634
25. L.P. Miranda, T. Tao, and A. Jones, et al. Total chemical synthesis and chemotactic activity of human S100A12 (EN-RAGE) FEBS Lett 488 2001 85 90
26. P. Rouleau, K. Vandal, and C. Ryckman The calcium-binding protein S100A12 induces neutrophil adhesion, migration, and release from bone marrow in mouse at concentrations similar to those found in human inflammatory arthritis Clin Immunol 107 2003 46 54
27. G. Fuellen, D. Foell, and W. Nacken, et al. Absence of S100A12 in mouse: implications for RAGE-S100A12 interaction Trends Immunol 24 2003 622 624
28. M.H. Kim, Y.W. Choi, and H.Y. Choi, et al. The expression of RAGE and EN-RAGE in leprosy Br J Dermatol 154 2006 594 601
29. K. Kawahara, K.K. Biswas, and M. Unoshima, et al. C-reactive protein induces high-mobility group box-1 protein release through activation of p38 MAPK in macrophage RAW264.7 cells Cardiovasc Pathol 17 2008 129 138
30. T. Hasegawa, A. Kosaki, and T. Kimura, et al. The regulation of EN-RAGE (S100A12) gene expression in human THP-1 macrophages Atherosclerosis 171 2003 211 218
31. B. Clyne, and J.S. Olshaker The C-reactive protein J Emerg Med 17 1999 1019 1025
32. K. Yasojima, C. Schwab, and E.G. Mc Geer, et al. Generation of C-reactive protein and complement components in atherosclerotic plaques Am J Pathol 158 2001 1039 1051
33. Y. Ichida, G. Hasegawa, and M. Fukui, et al. Effect of atorvastatin on in vitro expression of resistin in adipocytes and monocytes/macrophages and effect of atorvastatin treatment on serum resistin levels in patients with type 2 diabetes Pharmacology 76 2006 34 39
34. G. Qiu, and J.S. Hill Atorvastatin decreases lipoprotein lipase and endothelial lipase expression in human THP-1 macrophages J Lipid Res 48 2007 2112 2122
35. W.L. Hu, S.B. Qian, and J.J. Li Decreased C-reactive protein-induced resistin production in human monocytes by simvastatin Cytokine 40 2007 201 206
36. E. Kibayashi, M. Urakaze, and C. Kobashi, et al. Inhibitory effect of pitavastatin (NK-104) on the C-reactive protein-induced interleukin-8 production in human aortic endothelial cells Clin Sci 108 2005 515 521
37. M. Takata, M. Urakaze, and R. Temaru, et al. Pravastatin suppresses the interleukin-8 production induced by thrombin in human aortic endothelial cells cultured with high glucose by inhibiting the p44/42 mitogen activated protein kinase Br J Pharmacol 134 2005 753 762
38. A.P. Negre, A.K. Van Viiet, and M. Van Erck, et al. Inhibition of proliferation of human smooth muscle cells by various HMG-CoA reductase inhibitors; comparison with other human cell types Biochim Biophys Acta 1345 1997 259 268
39. S. Oi, T. Haneda, and J. Osaki, et al. Lovastatin prevents angiotensin II-induced cardiac hypertrophy in cultural neonatal rat heart cells Eur J Pharmacol 376 1999 139 148
40. S. Tsuchiya, M. Yamabe, and Y. Yamaguchi, et al. Establishment and characterization of a human acute monocytic leukaemia cell line (THP-1 cells) Int J Cancer 26 1980 171 176
41. A.J. Coats Ethical authorship and publishing Int J Cardiol 131 2009 149 150