'Induction of inflammatory gene expression by THP-1 macrophages cultured in normocholesterolaemic hypertensive sera and modulatory effects of green tea polyphenols'

Journal of Human Hypertension

Volumn 22, Issue 2, 2008, Pages 141-143

  Mahajan, N ^a   Dhawan, V ^a   Sharma, G ^a   Jain, S ^a   Kaul, D ^a  

^a POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE B; GREEN TEA EXTRACT; INTERLEUKIN 6; MESSENGER RNA; POLYPHENOL DERIVATIVE;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HUMAN; HUMAN CELL CULTURE; HYPERTENSION; IMMUNOMODULATION; INFLAMMATION; MACROPHAGE; SERUM; SYSTOLIC BLOOD PRESSURE;

ANTIOXIDANTS; CELLS, CULTURED; FLAVONOIDS; GENE EXPRESSION; HUMANS; HYPERTENSION; INTERLEUKIN-6; MACROPHAGES; MATRIX METALLOPROTEINASE 9; PHENOLS; PLANT EXTRACTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TEA;

EID: 38349177572     PISSN: 09509240     EISSN: 14765527     Source Type: Journal    
DOI: 10.1038/sj.jhh.1002277     Document Type: Article

References (8)

1. Intengan HD, Schiffrin EL. Vascular remodeling in hypertension, role of apoptosis, inflammation and fibrosis. Hypertension 2001; 38: 581-587.
2. Hertog MG, Feskens EJ, Hollman PC, Katan MB, Kromhout D. Dietary antioxidant flavanoids and risk of coronary heart disease: The Zutphen Elderly study. Lancet 1993; 342: 1007-1011.
3. JNC-VI. The sixth report of Joint National Committee on prevention, detection, evaluation and treatment of high blood pressure. Arch Intern Med 1997; 157: 2413-2446.
4. Kaul D, Shukla AR, Sikand K, Dhawan V. Effect of herbal polyphenols on atherosclerotic transcriptome. Mol Cell Biochem 2005; 278: 177-184.
5. Worley JR, Baugh MD, Hughes III DA, Edwards DR, Hogan A, Sampson MJ et al. Metalloproteinase expression in PMA stimulated THP-1 cells: effects of PPARγ agonists and 9-cis-retinoic acid. J Biol Chem 2003; 278: 51340-51346.
6. Kaul D, Sikand K, Shukla AR. Effect of green tea polyphenols on genes with atherosclerotic potential. Phytother Res 2004; 18: 177-179.
7. Liu Y, Liu T, McCarron RM, Spatz M, Feuerstein G, Hallenbeck JM et al Evidence for activation of endothelium and monocytes in hypertensive rats. Am J Physiol 1996; 270: H2125-H2131.
8. Heinrich PC, Castell JV, Andus T. Interleukin-6 and the acute phase response. Biochem J 1990; 265: 621-636.