Intracellular localization of sphingosine kinase 1 alters access to substrate pools but does not affect the degradative fate of sphingosine-1- phosphate

Journal of Lipid Research

Volumn 51, Issue 9, 2010, Pages 2546-2559

  Siow, Deanna L ^a   Anderson, Charles D ^a   Berdyshev, Evgeny V ^b,e   Skobeleva, Anastasia ^b,e   Pitson, Stuart M ^c,d   Wattenberg, Binks W ^a  

^a University of Louisville School of Medicine   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c CENTRE FOR CANCER BIOLOGY   (Australia)

^d UNIVERSITY OF ADELAIDE   (Australia)

^e UNIVERSITY OF ILLINOIS   (United States)

Author keywords

Ceramide; Lipid kinase; Phosphorylated sphingolipid; Sphingolipid metabolism; Sphingosine; Sphingosine 1 phosphate lyase

Indexed keywords

CERAMIDE; DIHYDROSPHINGOSINE 1 PHOSPHATE; LYASE; PHOSPHATASE; SPHINGANINE; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE KINASE 1; UNCLASSIFIED DRUG;

ARTICLE; CELL COMPARTMENTALIZATION; CELL MEMBRANE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; LIPID METABOLISM; LIPOGENESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING;

CELL MEMBRANE; CERAMIDES; ENDOPLASMIC RETICULUM; GENE KNOCKDOWN TECHNIQUES; HELA CELLS; HUMANS; LYSOPHOSPHOLIPIDS; MEMBRANE PROTEINS; PHOSPHORIC MONOESTER HYDROLASES; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); RECOMBINANT PROTEINS; SPHINGOSINE;

EID: 77956862615     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M004374     Document Type: Article

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