Recombinant activated factor VII is reabsorbed in renal proximal tubules and is a ligand to megalin and cubilin

Nephron - Experimental Nephrology

Volumn 117, Issue 3, 2011, Pages

  Seested, Torben ^a   Appa, Rupa Shree ^a   Jacobsen, Christian ^b   Christensen, Erik Ilso ^c  

^a NOVO NORDISK A S   (Denmark)

^b AARHUS UNIVERSITY   (Denmark)

^c AARHUS UNIVERSITY   (Denmark)

Author keywords

Cubilin; Megalin; Recombinant activated factor VII; Renal proximal tubules

Indexed keywords

CUBILIN; LIGAND; MEGALIN; RECEPTOR ASSOCIATED PROTEIN; RECEPTOR PROTEIN; RECOMBINANT BLOOD CLOTTING FACTOR 7A; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BINDING; ENDOCYTOSIS; ENDOSOME; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; KIDNEY CELL; KIDNEY CLEARANCE; KIDNEY CORTEX; KIDNEY PROXIMAL TUBULE; LYSOSOME; MALE; MOUSE; NONHUMAN; OPOSSUM KIDNEY CELL; PRIORITY JOURNAL; RAT; SURFACE PLASMON RESONANCE;

ANIMALS; CELLS, CULTURED; ENDOCYTOSIS; FACTOR VIIA; KIDNEY; KIDNEY TUBULES, PROXIMAL; LDL-RECEPTOR RELATED PROTEIN 2; MALE; MICE; OPOSSUMS; RATS; RECEPTORS, CELL SURFACE; RECOMBINANT PROTEINS; SURFACE PLASMON RESONANCE; TISSUE DISTRIBUTION;

EID: 77956831719     PISSN: 16602129     EISSN: None     Source Type: Journal    
DOI: 10.1159/000321161     Document Type: Article

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