Intramuscular AAV delivery of NT-3 alters synaptic transmission to motoneurons in adult rats

European Journal of Neuroscience

Volumn 32, Issue 6, 2010, Pages 997-1005

  Petruska, Jeffrey C ^a,d   Kitay, Brandon ^b   Boyce, Vanessa S ^a   Kaspar, Brian K ^c,e,f   Pearse, Damien D ^b   Gage, Fred H ^c   Mendell, Lorne M ^a  

^a STONY BROOK UNIVERSITY   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^c SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^d University of Louisville School of Medicine   (United States)

^e THE RESEARCH INSTITUTE AT NATIONWIDE CHILDREN S HOSPITAL   (United States)

^f OHIO STATE UNIVERSITY   (United States)

Author keywords

electrophysiology; gene therapy; spinal cord; viral vector

Indexed keywords

NEUROTROPHIN 3; VIRUS VECTOR;

ADENO ASSOCIATED VIRUS; ANIMAL EXPERIMENT; ARTICLE; EXCITATORY POSTSYNAPTIC POTENTIAL; FEMALE; GASTROCNEMIUS MUSCLE; MOTONEURON; MUSCLE SPINDLE AFFERENT NERVE; NONHUMAN; PRIORITY JOURNAL; RAT; SEROTYPE; SPINAL CORD; SPINAL GANGLION; SYNAPTIC TRANSMISSION;

AGE FACTORS; ANIMALS; CELL LINE; DEPENDOVIRUS; DRUG DELIVERY SYSTEMS; EXCITATORY POSTSYNAPTIC POTENTIALS; FEMALE; GENETIC VECTORS; HUMANS; INJECTIONS, INTRAMUSCULAR; MOTOR NEURONS; NEUROTROPHIN 3; RATS; RATS, SPRAGUE-DAWLEY; SYNAPTIC TRANSMISSION;

EID: 77956825686     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2010.07392.x     Document Type: Article

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