EPO-mediated reduction in Hamp expression in vivo corrects iron deficiency anaemia in TMPRSS6 deficiency

British Journal of Haematology

Volumn 151, Issue 1, 2010, Pages 106-109

  Peng, Hongfan ^a   Truksa, Jaroslav ^a,b   Lee, Pauline ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b INSTITUTE OF BIOTECHNOLOGY   (Czech Republic)

Author keywords

anaemia; erythropoietin; haemojuvelin; hepcidin; iron; matriptase 2

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENETIC PROTEIN 6; C REACTIVE PROTEIN; HEMOGLOBIN; HEMOJUVELIN; HEPCIDIN; INTERLEUKIN 6; MATRIPTASE; MESSENGER RNA; PROTEIN HAMP; PROTEIN TMPRSS 6; RECOMBINANT ERYTHROPOIETIN; SMAD4 PROTEIN; SMAD6 PROTEIN; SMAD7 PROTEIN; UNCLASSIFIED DRUG; ANTIMICROBIAL CATIONIC PEPTIDE; ERYTHROPOIETIN; HAMP1 PROTEIN, MOUSE; MATRIPTASE 2; MEMBRANE PROTEIN; RECOMBINANT PROTEIN; SERINE PROTEINASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ERYTHROPOIESIS; IN VIVO STUDY; IRON DEFICIENCY ANEMIA; IRON OVERLOAD; LETTER; MEAN CORPUSCULAR HEMOGLOBIN; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; THROMBOCYTE COUNT; ANEMIA, IRON-DEFICIENCY; ANIMAL; BIOSYNTHESIS; DEFICIENCY; DRUG EFFECTS; DRUG SCREENING; GENE EXPRESSION REGULATION; MUTANT MOUSE STRAIN; PROCEDURES;

ANEMIA, IRON-DEFICIENCY; ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; DRUG EVALUATION, PRECLINICAL; ERYTHROPOIETIN, RECOMBINANT; GENE EXPRESSION REGULATION; MEMBRANE PROTEINS; MICE; MICE, MUTANT STRAINS; SERINE ENDOPEPTIDASES; ERYTHROPOIETIN; HEPCIDINS; RECOMBINANT PROTEINS;

EID: 77956822859     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2010.08306.x     Document Type: Letter

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