Suppression of the hepcidin-encoding gene Hamp permits iron overload in mice lacking both hemojuvelin and matriptase-2/TMPRSS6

British Journal of Haematology

Volumn 147, Issue 4, 2009, Pages 571-581

  Truksa, Jaroslav ^a   Gelbart, Terri ^a   Peng, Hongfan ^a   Beutler, Ernest ^a   Beutler, Bruce ^a   Lee, Pauline ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Hemojuvelin; Hepcidin encoding gene; Iron; Matriptase; TMPRSS

Indexed keywords

BONE MORPHOGENETIC PROTEIN; HEMOJUVELIN; HEPCIDIN; INTERLEUKIN 6; IRON; MATRIPTASE; MATRIPTASE 2; MESSENGER RNA; SMAD PROTEIN; TRANSFERRIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENE; GENE EXPRESSION; GENE FUNCTION; GENE MUTATION; GENE REPRESSION; HAMP GENE; IRON BLOOD LEVEL; IRON DEFICIENCY; IRON OVERLOAD; MALE; MEAN CORPUSCULAR VOLUME; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; BONE MORPHOGENETIC PROTEINS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; HEPATOCYTES; INTERLEUKIN-6; IRON; IRON OVERLOAD; IRON, DIETARY; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; RNA, MESSENGER; SERINE ENDOPEPTIDASES; TRANSFERRIN; UP-REGULATION;

EID: 70350482508     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2009.07873.x     Document Type: Article

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