The minipig as an animal model in biomedical stem cell research

Source Book of Models for Biomedical Research

Volumn , Issue , 2008, Pages 241-248

  Vodicka, Petr ^a   Hlucilova, Jana ^a,b   Klima, Jiri ^a,b   Prochazka, Radek ^c   Ourednik, Jitka ^c   Ourednik, Vaclav ^c   Motlik, Jan ^a,b  

^a INSTITUTE OF ANIMAL PHYSIOLOGY AND GENETICS   (Czech Republic)

^b CHARLES UNIVERSITY   (Czech Republic)

^c IOWA STATE UNIVERSITY   (United States)

Author keywords

Animal model; Biomedicine; Cell transplantation; Epidermal stem cell; Mesenchymal stem cell; Method(ology); Minipig; Neural stem cell; Swine

Indexed keywords

EID: 77956820447     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-59745-285-4_27     Document Type: Chapter

References (46)

1. Kolber-Simonds D, Lai L, Watt SR, Denaro M, Arn S, Augenstein ML, et al. Production of alpha-1,3-galactosyltransferase null pigs by means of nuclear transfer with fibroblasts bearing loss of heterozygosity mutations. Proc Natl Acad Sci USA 2004;101:7335-7340.
2. Tseng YL, Kuwaki K, Dor FJ, Shimizu A, Houser S, Hisashi Y, et al. alpha1,3-Galactosyltransferase gene-knockout pig heart transplantation in baboons with survival approaching 6 months. Transplantation 2005;80:1493-1500.
3. Chapman LE, Wilson CA. Implications of the advent of homozygous alpha l,3-galactosyltransferase gene-deficient pigs on transmission of infectious agents. Xenotransplantation 2003;10:287-288.
4. Wood JC, Quinn G, Suling KM, Oldmixon BA, Van Tine BA, Cina R , et al. Identifi cation of exogenous forms of human-tropic porcine endogenous retrovirus in miniature swine. J Virol 2004;78:2494-2501.
5. Quinn G, Wood JC, Ryan DJ, Suling KM, Moran KM, Kolber-Simonds DL, et al. Porcine endogenous retrovirus transmission characteristics of galactose alpha1-3 galactose-deficient pig cells. J Virol 2004;78:5805-5811.
6. Levy GA, Ghanekar A, Mendicino M, Phillips MJ, Grant DR. The present status of xenotransplantation. Transplant Proc 2001;33: 3050-3052.
7. Kues WA, Niemann H. The contribution of farm animals to human health. Trends Biotechnol 2004;22:286-294.
8. Li M, Zhang D, Hou Y, Jiao L, Zheng X, Wang WH. Isolation and culture of embryonic stem cells from porcine blastocysts. Mol Reprod Dev 2003;65:429-434.
9. Li M, Ma W, Hou Y , Sun XF, Sun QY, Wang WH. Improved isolation and culture of embryonic stem cells from Chinese miniature pig. J Reprod Dev 2004;50:237-244.
10. Tsung HC, Du ZW, Rui R, Li XL, Bao LP, Wu J, et al. The culture and establishment of embryonic germ (EG) cell lines from Chinese mini swine. Cell Res 2003;13:195-202.
11. Park KI, Ourednik J, Ourednik V, Taylor RM, Aboody KS, Auguste KI, et al. Global gene and cell replacement strategies via stem cells. Gene Ther 2002;9:613-624.
12. Molenaar GJ, Hogenesch RI, Sprengers ME, Staal MJ. Ontogenesis of embryonic porcine ventral mesencephalon in the perspective of its potential use as a xenograft in Parkinson's disease. J Comp Neurol 1997;382:19-28.
13. Fink JS, Schumacher JM, Ellias SL, Palmer EP, Saint-Hilaire M, Shannon K, et al. Porcine xenografts in Parkinson's disease and Huntington's disease patients: Preliminary results. Cell Transplant 2000;9:273-278.
14. Schumacher JM, Ellias SA, Palmer EP, Kott HS, Dinsmore J, Dempsey PK, et al. Transplantation of embryonic porcine mesencephalic tissue in patients with PD. Neurology 2000;54:1042-1050.
15. Barker RA, Widner H. Immune problems in central nervous system cell therapy. NeuroRx 2004;1:472-481.
16. Ourednik J, Ourednik V, Lynch WP, Schachner M, Snyder EY. Neural stem cells display an inherent mechanism for rescuing dysfunctional neurons. Nat Biotechnol 2002;20:1103-1110.
17. Harrower TP, Tyers P, Hooks Y, Barker RA. Long-term survival and integration of porcine expanded neural precursor cell grafts in a rat model of Parkinson's disease. Exp Neurol 2006;197:56-69.
18. Mikkelsen M, Moller A, Jensen LH, Pedersen A, Harajehi JB, Pakkenberg H. MPTP-induced Parkinsonism in minipigs: A behavioral, biochemical, and histological study. Neurotoxicol Teratol 1999;21:169-175.
19. Cumming P, Gillings NM, Jensen SB, Bjarkam C, Gjedde A. Kinetics of the uptake and distribution of the dopamine D(2,3) agonist (R)-N-[1-(11)C]n- propylnorapomorphine in brain of healthy and MPTP-treated Gottingen miniature pigs. Nucl Med Biol 2003;30: 547-553.
20. Matsuyama N, Hadano S, Onoe K, Osuga H, Showguchi-Miyata J, Gondo Y, et al. Identifi cation and characterization of the miniature pig Huntington's disease gene homolog: Evidence for conservation and polymorphism in the CAG triplet repeat. Genomics 2000;69: 72-85.
21. Uchida M, Shimatsu Y, Onoe K, Matsuyama N, Niki R, Ikeda JE, et al. Production of transgenic miniature pigs by pronuclear microinjection. Transgenic Res 2001;10:577-582.
22. Ringe J, Kaps C, Schmitt B, Buscher K, Bartel J, Smolian H, et al. Porcine mesenchymal stem cells. Induction of distinct mesenchymal cell lineages. Cell Tissue Res 2002;307:321-327.
23. Bosch P, Pratt SL, Stice SL. Isolation, characterization, gene modifi-cation, and nuclear reprogramming of porcine mesenchymal stem cells. Biol Reprod 2006;74:46-57.
24. Moscoso I, Centeno A, Lopez E, Rodriguez-Barbosa JI, Santamarina I, Filgueira P, et al. Differentiation "in vitro" of primary and immortalized porcine mesenchymal stem cells into cardiomyocytes for cell transplantation. Transplant Proc 2005;37:481-482.
25. Orlic D. BM stem cells and cardiac repair: Where do we stand in 2004? Cytotherapy 2005;7:3-15.
26. Dib N, Diethrich EB, Campbell A, Gahremanpour A, McGarry M, Opie SR. A percutaneous swine model of myocardial infarction. J Pharmacol Toxicol Methods 2006;53:256-263.
27. Makkar RR, Price MJ, Lill M, Frantzen M, Takizawa K, Kleisli T, et al. Intramyocardial injection of allogenic bone marrow-derived mesenchymal stem cells without immunosuppression preserves cardiac function in a porcine model of myocardial infarction. J Cardiovasc Pharmacol Ther 2005;10:225-233.
28. Kamihata H, Matsubara H, Nishiue T, Fujiyama S, Tsutsumi Y, Ozono R, et al. Implantation of bone marrow mononuclear cells into ischemic myocardium enhances collateral perfusion and regional function via side supply of angioblasts, angiogenic ligands, and cytokines. Circulation 2001;104:1046-1052.
29. Freyman T, Polin G, Osman H, Crary J, Lu M, Cheng L, et al. A quantitative, randomized study evaluating three methods of mesenchymal stem cell delivery following myocardial infarction. Eur Heart J 2006;27:1114-1122.
30. Dick AJ, Guttman MA, Raman VK, Peters DC, Pessanha BS, Hill JM, et al. Magnetic resonance fluoroscopy allows targeted delivery of mesenchymal stem cells to infarct borders in swine. Circulation 2003;108:2899-2904.
31. Hill JM, Dick AJ, Raman VK, Thompson RB, Yu ZX, Hinds KA, et al. Serial cardiac magnetic resonance imaging of injected mesenchymal stem cells. Circulation 2003;108:1009-1014.
32. Kraitchman DL, Heldman AW, Atalar E, Amado LC, Martin BJ, Pittenger MF, et al. In vivo magnetic resonance imaging of mesenchymal stem cells in myocardial infarction. Circulation 2003;107: 2290-2293.
33. Carstens MH, Chin M, Li XJ. In situ osteogenesis: Regeneration of 10-cm mandibular defect in porcine model using recombinant human bone morphogenetic protein-2 (rhBMP-2) and Helistat absorbable collagen sponge. J Craniofac Surg 2005;16:1033-1042.
34. Mainil-Varlet P, Rieser F, Grogan S, Mueller W, Saager C, Jakob RP. Articular cartilage repair using a tissue-engineered cartilage-like implant: An animal study. Osteoarthritis Cartilage 2001;9(Suppl A): S6-15.
35. Liu Y, Chen F, Liu W, Cui L, Shang Q, Xia W, et al. Repairing large porcine full-thickness defects of articular cartilage using autologous chondrocyte-engineered cartilage. Tissue Eng 2002;8:709-721.
36. Sullivan TP, Eaglstein WH, Davis SC, Mertz P. The pig as a model for human wound healing. Wound Repair Regen 2001;9:66-76.
37. Middelkoop E, van den Bogaerdt AJ, Lamme EN, Hoekstra MJ, Brandsma K, Ulrich MM. Porcine wound models for skin substitution and burn treatment. Biomaterials 2004;25:1559-1567.
38. Matouskova E, Vogtova D, Konigova R. A recombined skin composed of human keratinocytes cultured on cell-free pig dermis. Burns 1993;19:118-123.
39. Ito M, Liu Y, Yang Z, Nguyen J, Liang F, Morris RJ, et al. Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis. Nat Med 2005;11:1351-1354.
40. Tumbar T, Guasch G, Greco V, Blanpain C, Lowry WE, Rendl M, et al. Defi ning the epithelial stem cell niche in skin. Science 2004;303:359-363.
41. Klima J, Smetana K Jr, Motlik J, Plzakova Z, Liu FT, Stork J, et al. Comparative phenotypic characterization of keratinocytes originating from hair follicles. J Mol Histol 2005;36:89-96.
42. Coyne TM, Akiva JM, Woodbury D, Black IB. Marrow stromal cells transplanted to the adult brain are rejected by an infl ammatory response and transfer donor labels to host neurons and glia. Stem Cells 2006;24(11):2483- 2492.
43. Vodicka P, Smetana K Jr, Dvorankova B, Emerick T, Xu YZ, Ourednik J, et al. The miniature pig as an animal model in biomedical research. Ann NY Acad Sci 2005;1049:161-171.
44. Hofmann A, Kessler B, Ewerling S, Weppert M, Vogg B, Ludwig H, et al. Efficient transgenesis in farm animals by lentiviral vectors. EMBO Rep 2003;4:1054-1060.
45. Nguyen TH, Khakhoulina T, Simmons A, Morel P, Trono D. A simple and highly effective method for the stable transduction of uncultured porcine hepatocytes using lentiviral vector. Cell Transplant 2005;14:489-496.
46. Arbab AS, Yocum GT, Rad AM, Khakoo AY, Fellowes V, Read EJ, et al. Labeling of cells with ferumoxides-protamine sulfate complexes does not inhibit function or differentiation capacity of hematopoietic or mesenchymal stem cells. NMR Biomed 2005;18: 553-559.