Stress-induced multiple organ damage in rats is ameliorated by the antioxidant and anxiolytic effects of regular exercise

Cell Biochemistry and Function

Volumn 28, Issue 6, 2010, Pages 469-479

  Çakir, Bariş ^a   Kasimay, Özgür ^a   Kolgazi, Meltem ^a   Ersoy, Yasemin ^a   Ercan, Feriha ^a   Yeǧen, Berrak Ç ^a  

^a MARMARA UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

Author keywords

Antioxidant; Malondialdehyde; Myeloperoxidase; Stress; Swimming

Indexed keywords

ASPARTATE AMINOTRANSFERASE; GLUTATHIONE; HYDROCORTISONE; MALONALDEHYDE; MYELOPEROXIDASE;

ACUTE STRESS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ANXIETY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BRAIN; CHRONIC STRESS; CONTROLLED STUDY; DECAPITATION; ENZYME ACTIVITY; EXERCISE; EXPLORATORY BEHAVIOR; FOOTSHOCK; FORCED SWIMMING TEST; HEART MUSCLE; HYDROCORTISONE BLOOD LEVEL; LIVER; MALE; MULTIPLE ORGAN FAILURE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; SITTING; SKELETAL MUSCLE; STOMACH; STRESS; TRANQUILIZING ACTIVITY;

ANIMALS; ANXIETY DISORDERS; BRAIN; DISEASE MODELS, ANIMAL; EXERCISE THERAPY; GLUTATHIONE; HUMANS; LIVER; MALE; MALONDIALDEHYDE; MUSCLE, SKELETAL; OXIDATIVE STRESS; PEROXIDASE; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; STRESS, PHYSIOLOGICAL; SWIMMING;

ANIMALIA; RATTUS;

EID: 77956799066     PISSN: 02636484     EISSN: 10990844     Source Type: Journal    
DOI: 10.1002/cbf.1679     Document Type: Article

References (50)

1. Liu JK, Mori A. Stress, aging, brain oxidative damage. Neurochem Res 1999; 24: 1479-1497.
2. Laudenslager ML, Ryan SM, Drugan RC, Hyson RL, Maier SF. Coping and immunosuppression: Inescapable but not escapable shock suppresses lymphocyte proliferation. Science 1983; 221: 568-570.
3. Okimura T, Nigo Y. Stress and immune responses: Suppression of T cell function in restraint-stressed mice. Jpn J Pharmacol 1986; 40: 505-511.
4. Sklar LS, Anisman H. Stress and coping factors influence tumor growth. Science 1979; 205: 513-515.
5. Sant'anna ID, de Sousa EB, de Moraes AV, Loures DL, Mesquita ET, da Nobrega AC. Cardiac function during mental stress: Cholinergic modulation with pyridostigmine in healthy subjects. Clin Sci 2003; 105: 161-165.
6. Salmon P. Effects of the physical exercise on anxiety, depression, and sensitivity to stress: A unifying theory. Clin Psychol Rev 2001; 21: 33-61.
7. Sen CK, Atalay M, Agren J, Laaksonen DE, Roy S, Hanninen O. Fish oil and vitamin E supplementation in oxidative stress at rest and after physical exercise. J Appl Physiol 1997; 83: 189-195.
8. Kumar CT, Reddy VK, Prasad M, Thyagaraju K, Reddana P. Dietary supplementation of vitamin E protects heart tissue from exerciseinduced oxidant stress. Mol Cell Biochem 1992; 111: 109-115.
9. Reddy VK, Kumar CT, Prasad M, Reddanna P. Exercise-induced oxidant stress in the lung tissue: Role of dietary supplementation of vitamin E and selenium. Bio-chem Int 1992; 26: 863-871.
10. Davies KJ, Quintanilha AT, Brooks GA, Packer L. Free radicals and tissue damage produced by exercise. Biochem Biophys Res Commun 1982; 107: 1198-1205.
11. Kalani R, Judge S, Carter C, Pahor M, Leeuwenburgh C. Effects of caloric restriction and exercise on age-related, chronic inflammation assessed by CRP and interleukin-6. J Gerontol A Biol Sci Med Sci 2006; 61: 211-217.
12. Navarro A, Gomez C, Lopez-Cepero JM, Boveris A. Beneficial effects of moderate exercise on mice aging: Survival, behavior, oxidative stress, and mitochondrial electron transfer. Am J Physiol Regul Integr Comp Physiol 2004; 286: R505-R511.
13. Kihlström M. Protection effect of endurance training against reoxygenation- induced injuries in rat heart. J Appl Physiol 1990; 68: 1672-1678.
14. Lew H, Quintanilha A. Effects of endurance training and exercise on tissue antioxidative capacity and acetaminophen detoxification. Eur J Drug Metab Pharmacokinet 1991; 16: 59-68.
15. Terblanche SE. The effects of exhaustive exercise on the activity levels of catalase in various tissues of male and female rats. Cell Biol Int 2000; 23: 749-753.
16. Lima FD, Oliveira MS, Furian AF, et al. Adaptation to oxidative challenge induced by chronic physical exercise prevents Na+,K+- ATPase activity inhibition after traumatic brain injury. Brain Res 2009; 1279: 147-155.
17. Peijie C, Hongwu L, Fengpeng X, Jie R, Jie Z. Heavy load exercise induced dysfunction of immunity and neuroendocrine responses in rats. Life Sci 2003; 72: 2255-2262.
18. Gülpinar MA, Özbeyli D, Arbak S, Yeǧen BÇ. Anti-inflammatory effect of acute stress on experimental colitis mediated by cholecystokinin- B receptors. Life Sci 2004; 75: 77-91.
19. Marco EM, Llorente R, Pérez-Alvarez L, Moreno E, Guaza C, Viveros MP. The kappa-opioid receptor is involved in the stimulating effect of nicotine on adrenocortical activity but not in nicotine induced anxiety. Behav Brain Res 2005; 163: 212-218.
20. File SE,Wardill AG. Validity of head-dipping as a measure of exploration in a modified hole-board. Psychopharmacologia 1975; 44: 53-59.
21. Boissier JR, Simon P. The exploration reaction in the mouse. Therapie 1962; 17: 1225-1232.
22. Buege JL, Aust SD. Microsomal lipid peroxidation. Methods Enzymol 1978; 52: 302-311.
23. Beutler E. 1975; Glutathione. In: Red Blood Cell Metabolism: A Manual of Biochemical Methods, Beutler E (ed). Grune & Stratton: New York, 112-114.
24. Bradley PP, Priebat DA, Christersen RD, Rothstein G. Measurement of cutaneous inflammation. Estimation of neutrophil content with an enzyme marker. J Invest Dermatol 1982; 78: 206-209.
25. Hillegas LM, Griswold DE, Brickson B, Albrightson-Winslow C. Assesment of myeloperoxidase activity in whole rat kidney. J Pharmacol Methods 1990; 24: 285-295.
26. Sener G, Toklu H, Kapucu C, et al. Melatonin protects against oxidative organ injury in a rat model of sepsis. Surg Today 2005; 35: 52-59. (Pubitemid 40941131)
27. Sen CK, Packer L, Hanninen O (eds). Exercise and Oxygen Toxicity. Elsevier Science Publishers BV: Amsterdam, 1994.
28. Powers SK, Criswell D, Lawler J, et al. Rigorous exercise training increases superoxide dismutase activity in ventricular myocardium. Am J Physiol 1993; 265: H2094-H2098.
29. Quintanilha AT. Effects of physical exercise and/or vitamin E on tissue oxidative metabolism. Biochem Soc Trans 1984; 12: 403-404.
30. Kim JD, Yu BP, McCarter RJ, Lee SY, Herlihy JT. Exercise and diet modulate cardiac lipid peroxidation and antioxidant defenses. Free Radic Biol Med 1996; 20: 83-88.
31. Ji LL, Fu RG, Mitchell EW, Griffiths M, Waldrop TG, Swartz HM. Cardiac hypertrophy alters myocardial response to ischaemia and reperfusion in vivo. Acta Physiol Scand 1994; 151: 279-290.
32. Venditti P, Di Meo S. Effect of training on antioxidant capacity, tissue damage, and endurance of adult male rats. Int J Sports Med 1997; 18: 497-502.
33. Soukup T, Zachařová G, Smerdu V. Fibre type composition of soleus and extensor digitorum longus muscles in normal female inbred Lewis rats. Acta Histochem 2002; 104: 399-405.
34. Ji LL, Gomez-Cabrera MC, Vina J. Role of free radicals and antioxidant signaling in skeletal muscle health and pathology. Infect Disord Drug Targets 2009; 9: 428-444.
35. Silva LA, Pinho CA, Scarabelot KS, et al. Physical exercise increases mitochondrial function and reduces oxidative damage in skeletal muscle. Eur J Appl Physiol 2009; 105: 861-867.
36. Ji LL, Fu R. Responses of glutathione system and antioxidant enzymes to exhaustive exercise and hydroperoxide. J Appl Physiol 1992; 72: 549-554.
37. Venditti P, Masullo P, Di Meo S. Effect of Exercise Duration on Characteristics of Mitochondrial Population from Rat Liver. Arch Biochem Biophys 1999; 368: 112-120. (Pubitemid 29372311)
38. AoiW, Ichiishi E, Sakamoto N, Tsujimoto A, Tokuda H, Yoshikawa T. Effect of exercise on hepatic gene expression in rats: A microarray analysis. Life Sci 2004; 75: 3117-3128.
39. Huang CC, Lin WT, Hsu FL, Tsai PW, Hou CC. Metabolomics investigation of exercise-modulated changes in metabolism in rat liver after exhaustive and endurance exercises. Eur J Appl Physiol 2009; DOI: 10.1007/s00421-009- 1247-1257
40. Lambert GP. Intestinal barrier dysfunction, endotoxemia, and gastrointestinal symptoms: The 'canary in the coal mine' during exercise-heat stress? Med Sport Sci 2008; 53: 61-73.
41. Peters HP, De Vries WR, Vanberge-Henegouwen GP, Akkermans LM. Potential benefits and hazards of physical activity and exercise on the gastrointestinal tract. Gut 2001; 48: 435-439.
42. Kasimay O, Güzel E, Gemici A, et al. Colitis-induced oxidative damage of the colon and skeletal muscle is ameliorated by regular exercise in rats: The anxiolytic role of exercise. Exp Physiol 2006; 91: 897-906.
43. Howells FM, Russell VA, Mabandla MV, Kellaway LA. Stress reduces the neuroprotective effect of exercise in a rat model for Parkinson's disease. Behav Brain Res 2005; 165: 210-220.
44. Marais L, Stein DJ, Daniels WM. Exercise increases BDNF levels in the striatum and decreases depressive-like behavior in chronically stressed rats. Metab Brain Dis 2009; DOI: 10.1007/s11011-009- 9157-9162
45. Kirschner PB, Jenkins BG, Schulz JB, et al. NGF, BDNF and NT-5, but not NT-3 protect against MPP+toxicity and oxidative stress in neonatal animals. Brain Res 1996; 713: 178-185.
46. Wipfli BM, Rethorst CD, Landers DM. The anxiolytic effects of exercise: A meta-analysis of randomized trials and dose-response analysis. J Sport Exerc Psychol 2008; 30: 392-410.
47. Staats R, Balkow S, Sorichter S, et al. Change in perforin-positive peripheral blood lymphocyte (PBL) subpopulations following exercise. Clin Exp Immunol 2000; 120: 434-439.
48. Pedersen BK, Steensberg A, Fischer C, Keller C, Ostrowski K, Schjerling P. Exercise and cytokines with particular focus on muscle-derived IL-6. Exerc Immunol Rev 2001; 7: 18-31.
49. Munhoz CD, García-Bueno B, Madrigal JL, Lepsch LB, Scavone C, Leza JC. Stress-induced neuroinflammation: Mechanisms and new pharmacological targets. Braz J Med Biol Res 2008; 41: 1037-1046.
50. Tvede N, Kappel M, Halkjaer-Kristensen J, Galbo H, Pedersen BK. The effect of light, moderate and severe bicycle exercise on lymphocyte subsets, natural and lymphokine activated killer cells, lymphocyte proliferative response and interleukin 2 production. Int J Sports Med 1993; 14: 275-282.