Effect of exercise on hepatic gene expression in rats: A microarray analysis

Life Sciences

Volumn 75, Issue 26, 2004, Pages 3117-3128

  Aoi, Wataru ^a   Ichiishi, Eiichiro ^a   Sakamoto, Naoyuki ^a   Tsujimoto, Atsumi ^b   Tokuda, Harukuni ^a   Yoshikawa, Toshikazu ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b DNA CHIP RESEARCH INC   (Japan)

Author keywords

Exercise training; Gene expression; Liver; Microarray; P38; Stat3

Indexed keywords

COMPLEMENTARY DNA; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; STAT3 PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DNA MICROARRAY; DOWN REGULATION; EXERCISE; GENE EXPRESSION; GENE FUNCTION; GENETIC TRANSCRIPTION; LIVER; LIVER FUNCTION; MALE; MOLECULAR BIOLOGY; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYSICAL ACTIVITY; RAT; RUNNING; UNINDEXED SEQUENCE; UPREGULATION;

ANIMALS; BLOTTING, WESTERN; DNA PRIMERS; DNA-BINDING PROTEINS; EXERTION; GENE EXPRESSION REGULATION; LIVER; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS;

ANIMALIA;

EID: 5444254450     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2004.04.053     Document Type: Article

References (36)

1. S. Akira Functional roles of STAT family proteins: lessons from knockout mice Stem Cells 17 3 1999 138 146
2. F. Amersi, X.D. Shen, D. Anselmo, J. Melinel, S. Lyer, D.J. Southard, M. Katori, H.D. Volk, R.W. Busuttil, R. Buelow, and J.W. Kupiec-Weglinski Ex vivo exposure to carbon monooxide prevents hepatic ischemia/reperfusion injury through p38 MAPkinase pathway Hepatology 35 4 2002 815 823
3. J.G. Bode, P. Gatsios, S. Ludwig, U.R. Rapp, D. Haussinger, P.C. Heinrich, and L. Graeve The mitogen-activated protein (MAP) kinase p38 and its upstream activator MAP kinase kinase 6 are involved in the activation of signal transducer and activator of transcription by hyperosmolarity Journal of Biological Chemistry 274 42 1999 30222 30227
4. G.D. Cartee, and R.P. Farrar Exercise training induces glycogen sparing during exercise by old rats Journal of Applied Physiology 64 1 1988 259 265
5. G.M. Diffee, E.A. Seversen, T.D. Stein, and J.A. Johnson Microarray expression analysis of effects of exercise training: increase in atrial MLC-1 in rat ventricles American Journal of Physiology Heart and Circulatory Physiology 284 3 2003 H830 H837
6. C.M. Donovan, and K.D. Sumida Training enhanced hepatic gluconeogenesis: the importance for glucose homeostasis during exercise Medicine and Science in Sports and Exercise 29 5 1997 628 634
7. T.M. Dyke, R.A. Sams, and K.W. Hinchcliff Exercise-training-induced alterations in hepatic function in mares Journal of Applied Physiology 85 4 1998 1442 1447
8. R.G. Fiebig, J.M. Hollander, D. Ney, R. Boileau, E. Jeffery, and L.L. Ji Training down-regulates fatty acid synthase and body fat in obese Zucker rats Medicine and Science in Sports and Exercise 34 7 2002 1106 1114
9. R. Frenkl, A. Gyore, and S. Szeberenyi The effect of muscular exercise on the microsomal enzyme system of the rat liver European Journal of Applied Physiology 44 2 1980 135 140
10. J. Gorski, L.B. Oscai, and W.K. Palmer Hepatic lipid metabolism in exercise and training Medicine and Science in Sports and Exercise 22 2 1990 213 221
11. S. Haga, K. Terui, H.Q. Zhang, S. Enosawa, W. Ogawa, H. Inoue, T. Okuyama, K. Takeda, S. Akira, T. Ogino, K. Irani, and M. Ozaki Stat3 protects against Fas-induced liver injury by redox-dependent and -independent mechanisms Journal of Clinical Investigation 112 7 2003 989 998
12. D. Haussinger, F. Schliess, F. Dombrowski, and S. vom Dahl Involvement of p38 MAPK in the regulation proteolysis by liver cell hydration Gastroenterology 116 1999 921 935
13. D. Haussinger, D. Graf, and O.H. Weiergraber Glutamine and cell signaling in liver Journal of Nutrition 131 2001 2509S 2514S
14. H. Inoue, W. Ogawa, M. Ozaki, S. Haga, M. Matsumoto, K. Furukawa, N. Hashimoto, Y. Kido, T. Mori, H. Sakaue, K. Teshigawara, S. Jin, H. Iguchi, R. Hiramatsu, D. LeRoith, K. Takeda, S. Akira, and M. Kasuga Role of stst-3 in regulation of hepatic gluconeogenic genes and carbohydrate metabolism in vivo Nature Medicine 10 2 2004 168 174
15. J.P. Kirwan, and L.F. del Aguila Insulin signalling, exercise and cellular integrity Biochemical Society Transactions 31 6 2003 1281 1285
16. Z. Li, T. Murakami, N. Nakai, M. Nagasaki, M. Obayashi, M. Xu, J. Sato, Y. Oshida, Y. Sato, and Y. Shimomura Modification by exercise training of activity and enzyme expression of hepatic branched-chain alpha-ketoacid dehydrogenase complex in streptozotocin-induced diabetic rats Journal of Nutritional Science and Vitaminology (Tokyo) 47 5 2001 345 350
17. T. Liqi, H. Shen, V.M. Perreau, R. Balazs, and C.W. Cotman Effects of exercise on gene-expression profile in the rat hippocampus Neurobiology of Disease 8 6 2001 1046 1056
18. J.L. Mauriz, B. Tabernero, J. Garcia-Lopez, F. Jorquera, J.G. Villa, and J. Gonzalez-Gallego Physical exercise and improvement of liver oxidative metabolism in the elderly European Journal of Applied Physiology 81 1-2 2000 62 66
19. J.L. Nieto, I. Diaz-Laviada, A. Guillen, and A. Haro Effect of endurance physical training on rat liver adenylyl cyclase system Cellular Signalling 8 4 1996 317 322
20. T. Ookawara, K. Suzuki, S. Haga, S. Ha, K.S. Chung, K. Toshinai, T. Hamaoka, T. Katsumura, T. Takemasa, M. Mizuno, Y. Hitomi, T. Kizaki, K. Suzuki, and H. Ohno Transcriptional regulation of gene expression in human skeletal muscle in response to endurance training Research Communications in Molecular Pathology and Pharmacology 111 1-4 2002 41 54
21. A. Paul, S. Wilson, C.M. Belham, C.J. Robinson, P.H. Scott, G.W. Gould, and R. Plevin Stress-activated protein kinases: activation, regulation and function Cellular Signalling 9 6 1997 403 410
22. D.A. Podolin, M.J. Pagliassotti, T.T. Gleeson, and R.S. Mazzeo Influence of endurance training on the age-related decline in hepatic glyconeogenesis Mechanisms of Ageing and Development 75 1 1994 81 93
23. C.P. Reddy Avula, and G. Fernandes Modulation of antioxidant enzymes and lipid peroxidation in salivary gland and other tissues in mice by moderate treadmill exercise Aging (Milano) 11 4 1999 246 252
24. S. Ritland Exercise and liver disease Sports Medicine 6 2 1988 121 126
25. P.J. Roach Glycogen and its metabolism Current Molecular Medicine 2 2 2002 101 120
26. S.M. Roth, G.F. Martel, R.E. Ferrell, E.J. Metter, B.F. Hurley, and M.A. Rogers Myostatin gene expression is reduced in humans with heavy-resistance strength training: a brief communication Experimental Biology and Medicine 228 6 2003 706 709
27. C. Schudt Influence of insulin, glucocorticoids and glucose on glycogen synthase activity in hepatocyte cultures Biochimica et Biophysica Acta 629 3 1980 499 509
28. C. Simonelli, and R.P. Eaton Reduced triglyceride secretion: a metabolic consequence of chronic exercise American Journal of Physiology 234 3 1978 E221 E227
29. B. Stoll, W. Gerok, F. Lang, and D. Haussinger Liver cell volume and protein synthesis Biochemica Journal 287 1 1992 217 222
30. B.J. Thompson, C.A. Shang, and M.J. Waters Identification of genes induced by growth hormone in rat liver using cDNA arrays Endocrinology 141 11 2000 4321 4324
31. P. Venditti, and S. Di Meo Antioxidants, tissue damage, and endurance in trained and untrained young male rats Archives of Biochemistry and Biophysics 331 1 1996 63 68
32. P. Venditti, and S. Di Meo Effect of training on antioxidant capacity, tissue damage, and endurance of adult male rats International Journal of Sports Medicine 18 7 1997 497 502
33. L. Wideman, J.Y. Weltman, M.L. Hartman, J.D. Veldhuis, and A. Weltman Growth hormone release during acute and chronic aerobic and resistance exercise: recent findings Sports Medicine 32 15 2002 987 1004
34. M. Wittwer, R. Billeter, H. Hoppeler, and M. Fluck Regulatory gene expression in skeletal muscle of highly endurance-trained humans Acta Physiologica Scandinavica 180 2 2004 217 227
35. S. Zanconato, D.Y. Moromisato, M.Y. Moromisato, J. Woods, J.A. Brasel, D. Leroith, C.T. Roberts Jr., and D.M. Cooper Effect of training and growth hormone suppression on insulin-like growth factor I mRNA in young rats Journal of Applied Physiology 76 5 1994 2204 2209
36. A. Zauberman, D. Zipori, M. Krupsky, and R. Ben-Levy Stress activated protein kinase p38 is involved in IL-6 induced transcriptional activation of stat3 Oncogene 18 26 1999 3886 3893