Exercise and cytokines with particular focus on muscle-derived il-6

Exercise Immunology Review

Volumn 7, Issue , 2001, Pages 18-31

  Pedersen, B K ^a   Steensberg, A ^a   Fischer, C ^a   Keller, C ^a   Ostrowski, K ^a   Schjerling, P ^a  

^a Rigshospitalet   (Denmark)

Author keywords

Cytokines; Exercise; Interleukin; Training

Indexed keywords

CYTOKINE; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; INTERLEUKIN 6; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR;

BLOOD LEVEL; EXERCISE; HUMAN; LIPOLYSIS; MALE; MARATHON RUNNER; MUSCLE CONTRACTION; MUSCLE METABOLISM; REVIEW; SKELETAL MUSCLE;

ANIMALS; CYTOKINES; EPINEPHRINE; EXERCISE; HUMANS; INTERLEUKIN-6; MUSCLE, SKELETAL; STRESS, MECHANICAL;

EID: 0034813001     PISSN: 10775552     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (44)

1. IL-6: Insights into novel biological activities
2. Exercise-induced increase in interleukin-6 is related to muscle damage
3. Some aspects of the acute phase response after a marathon race, and the effects of glutamine supplementation
4. Effects of training on exercise-induced muscle damage and interleukin 6 production
5. Induction of plasma interleukin-6 by circulating adrenaline in the rat
6. Role of interleukin-1 in infectious diseases
7. Endurance run increases circulating IL-6 and IL-1ra but downregulates ex vivo TNF-alpha and IL-1beta production
8. Interleukins and exercise
9. Effect of physical exercise on in vitro production of interleukin 1, interleukin 6, tumor necrosis factor-alpha, interleukin 2 and interferon-gamma
10. Role of cytokines in sepsis
11. Xanthine oxidase in human skeletal muscle following eccentric exercise: A role of inflammation
12. Muscle contractions induces interleukin-6 mRNA production in rat skeletal muscles
13. Interleukin 1beta and interleukin 6, but not tumor necrosis factor alpha, inhibit insulin-stimulated glycogen synthesis in rat hepatocytes
14. Hypoxemia increases serum interleukin-6 in humans
15. Markers of inflammation and myofibrillar proteins following eccentric exercise in humans
16. Recombinant interleukin-6 activates the hypothalamic-pituitary-adrenal axis in humans
17. Interactions of adrenaline and TNF and IL-6 in the control of lipolysis from adipocytes around lymph nodes
18. Carbohydrate and the cytokine response to 2.5 h of running
19. Lymphocytes and NK cell activity during repeated bouts of maximal exercise
20. Expression of the inducible nitric oxide synthase (iNOS) in human leukocytes: Responses to running exercise
21. Immunologic mediators as parameters of the reaction to strenuous exercise
22. Chemokines are elevated in plasma after strenuous exercise in humans
23. Physical activity and plasma interleukin-6 in humans-effect of intensity of exercise
24. A trauma-like elevation in plasma cytokines in humans in response to treadmill running
25. The cytokine balance and strenuous exercise: TNF-alpha, IL-2beta, IL-6, IL-1ra, sTNF-r1, sTNF-r2, and IL-10
26. Evidence that IL-6 is produced in skeletal muscle during intense long-term muscle activity
27. Exercise and interleukin-6
28. Exercise and the immune system: Regulation, integration and adaption
29. Exercise and immunology: Integration and regulation
30. The cytokine response to strenuous exercise
31. Dynamic exercise leads to an increase in circulating ICAM-1: Further evidence for adrenergic modulation of cell adhesion
32. Role of cytokines in acute-phase response
33. Prolonged submaximal eccentric exercise is associated with increased levels of plasma IL-6
34. Enhanced release of cytokines, interleukin-2 receptors, and neopterin after long-distance running
35. Carbohydrate ingestion attenuates the increase in plasma interleukin 6, but not skeletal muscle interleukin 6 mRNA, during exercise in humans
36. Production of interleukin-6 in contracting human skeletal muscles can account for the exercise-induced increase in plasma-IL-6 and is inversely related to glycogen content
37. Plasma interleukin-6 during strenuous exercise-role of adrenaline
38. Production of IL-6 in contracting human skeletal muscles can account for the exercise-induced increase in plasma IL-6
39. Endocrinologic and metabolic effects of interleukin-6 in humans
40. Induction of interleukin-1beta and interleukin-6 gene expression in hypoperfused skeletal muscle of patients with peripheral arterial disease
41. Dose-dependent effects of recombinant human interleukin-6 on glucose regulation
42. Bicycle exercise enhances plasma IL-6 but does not change IL-1 alpha, IL1beta, IL-6, or TNF-alpha pre-mRNA in BMNC
43. Effect of exhaustive exercise stress on the cytokine response
44. IL-6 is an antiinflammatory cytokine required for controlling local or systemic acute inflammatory responses