Chapter 1 Mapping Structure/Function Relations in αbENaC

Current Topics in Membranes and Transport

Volumn 47, Issue C, 1999, Pages 3-24

  Fuller, C M ^a   Ismailov, I I ^a   Berdiev, B K ^a   Shlyonsky, V Gh ^a   Benos, D J ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 77956657799     PISSN: 00702161     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0070-2161(08)60949-1     Document Type: Article

References (67)

1. + channel. J. Gen. Physiol. 108 (1996) 49-65
2. Benos D.J., Saccomani G., Brenner B.M., and Sariban-Sohraby S. Purification and characterization of the amiloride-sensitive sodium channel from A6 cultured cells and bovine renal papilla. Proc. Natl. Acad. Set. U.S.A. 83 (1986) 8525-8529
3. Benos D.J., Saccomani G., and Sariban-Sohraby S. The epithelial sodium channel. Subunit number and location of the amiloride binding site. J. Biol. Chem. 262 (1987) 10613-10618
4. + channels: Insights and outlooks. News Physiol. Sci. 12 (1997) 55-61
5. Berdiev B.K., Prat A.G., Cantiello H.F., Ausiello D.A., Fuller C.M., Jovov B., Benos D.J., and Ismailov I.I. Regulation of epithelial sodium channels by short actin filaments. J. Biol Chem. 271 (1996) 17704-17710
6. + channel (ENaC). Physiologist 40 (1997) A7 (abstr. 7.6)
7. + channels in rat kidney medulla. Am. J. Physiol. 256 (1989) F366-F369
8. + channels by β-subunit mutation. Am. J. Physiol. 270 (1996) C208-C213
9. Canessa C.M., Horisberger J.-D., and Rossier B.C. Epithelial sodium channel related to proteins involved in neurodegeneration. Nature (London) 361 (1993) 467-470
10. Canessa C.M., Merrilat A.-M., and Rossier B.C. Membrane topology of the epithelial sodium channel. Am. J. Physiol. 267 (1994) C1682-C1690
11. + channel is made of three homologous subunits. Nature (London) 367 (1994) 463-467
12. + channels from M-1 cortical collecting duct cells. Am. J. Physiol. 271 (1996) F861-F870
13. Chalfant M.L., Karlson K.H., McCoy D.E., Halpin P.A., Loffing D.N., and Stanton B.A. Possible role of the N-terminus of α-rENaC in sodium channel function. Physiologist 40 (1997) A8 (abstr. 7.11)
14. Chang S.S., Grunder S., Rosier A., Mathew P.M., Hanukoglu I., Schild L., Lu Y., Shimkets R.A., Nelson-Williams Rossier C.B.C., and Lifton R.P. Mutations in subunits of the epithelial sodium channel cause salt wasting with hyperkalaemic acidosis, pseudohypoaldosteronism type I. Nat. Genet. 12 (1996) 248-253
15. Driscoll M., and Chalfie M. The mec-4 gene is a member of a family of Caenorhabditis elegans genes that can mutate to induce neuronal degeneration. Nature (London) 349 (1991) 588-593
16. Firsov D., Gautschi I., Merillat A.M., Rossier B.C., and Schild L. The heterotetra-meric architecture of the epithelial sodium channel (ENaC). EMBO J. 17 (1998) 344-352
17. Frings S.M., Purves R.D., and MacKnight A.D.C. Single channel recordings from the apical membrane of the toad urinary bladder epithelial cell. J. Membr. Biol. 106 (1988) 157-172
18. + channel subunit. Am. J. Physiol. 269 (1995) C641-C654
19. + channel by C-terminal truncation of the bovine subunit. J. Biol. Chem. 271 (1996) 26602-26608
20. Fuller C.M., Berdiev B.K., Shlyonsky V.G., Ismailov I.I., and Benos D.J. Point mutations in αbENaC regulate channel gating, ion selectivity and sensitivity to amiloride. Biophys. J. 72 (1997) 1622-1632
21. Garcia-Anoveros J., Derfler B., Neville-Golden J., Hyman B.T., and Corey D.P. BNaCl and BNaC2 constitute a new family of human neuronal sodium channels related to degenerins and epithelial sodium channels. Proc. Natl. Acad. Sci. U.S.A. 94 (1997) 1459-1464
22. Garty H., and Palmer L. Epithelial sodium channels: Function, structure and regulation. Physiol. Rev. 77 (1997) 359-396
23. Grunder S., Firsov D., Chang S.S., Jaeger N.F., Gautschi I., Schild L., Lifton R.P., and Rossier B.C. A mutation causing pseudohypoaldosteronism type I identifies a conserved glycine that is involved in the gating of the epithelial sodium channel. EMBO J. 16 (1997) 899-907
24. Hamilton K.L., and Eaton D.C. Single-channel recordings from amiloride-sensitive epithelial sodium channel. Am. J. Physiol. 249 (1985) C200-C207
25. Hansson J.H., Nelson-Williams Suzuki C., Schild H.L., Shimkets R., Lu Y., Canessa Iwaski C., Rossier T.B., and Lifton R.P. Hypertension caused by a truncated epithelial sodium channel gamma subunit: Genetic heterogeneity of Liddle syndrome. Nat. Genet. 11 (1995) 76-82
26. Hansson J.H., Schild L., Lu Y., Wilson T.A., Gautschi I., Shimkets R., Nelson-Williams C., Rossier B.C., and Lifton R.P. A de novo missense mutation of the beta subunit of the epithelial sodium channel causes hypertension and Liddle syndrome, identifying a proline-rich segment critical for regulation of channel activity. Proc. Natl. Acad. Sci. U.S.A. 92 (1995) 11495-11499
27. + channels in planar bilayer membranes. J. Biol. Chem. 269 (1994) 10235-10241
28. + channels in Liddle's disease. Am. J. Physiol. 270 (1996) C214-C223
29. + channel function. J. Membr. Biol. 149 (1996) 123-132
30. + channel subunit. Am. J. Physiol. 271 (1996) 807-816
31. + channel. J. Biol. Chem. 272 (1997) 21075-21083
32. + channel antibody raised by an anti-idiotypic route. J. Biol. Chem. 266 (1991) 3907-3915
33. + channels. Am. J. Physiol. 254 (1988) C802-C808
34. Li X.-J., Xu R.-H., Guggino W.B., and Snyder S.H. Alternatively spliced forms of the α subunit of the epithelial sodium channel: Distinct sites for amiloride binding and channel pore. Mol. Pharmacol. 47 (1995) 1133-1140
35. Lingueglia E., Champigny G., Lazdunski M., and Barbry P. Cloning of the amiloride-sensitive FMRFamide peptide-gated sodium channel. Nature (London) 378 (1995) 730-733
36. Marunaka Y., and Eaton D.C. Effects of vasopressin and cAMP on single amiloride-blockade Na channels. Am. J. Phnysiol. 260 (1991) C1071-C1084
37. Oh Y.S., Smith P.R., Bradford A.L., Keeton D., and Benos D.J. Regulation byphosphorylation of purified epithelial Na channels in planar lipid bilayers. Am. J. Physiol. 265 (1993) C85-C91
38. + channels from the apical membrane of the rat cortical collecting tubule. Proc. Natl. Acad. Sci. U.S.A. 83 (1986) 2767-2770
39. Palmer L.G., and Frindt G. Epithelial sodium channels: Characterization by using the patch-clamp technique. Fed. Proc, Fed. Am. Soc. Exp. Biol. 45 (1986) 2708-2712
40. Ca channels from Xenopus oocytes to lipid bilayers. Biophys. J. 66 (1994) 1022-1027
41. Perozo E., Santacruz-Toloza L., Stefani E., Bezanilla F., and Papazian D.M. S4 mutations alter gating currents of Shaker K channels. Biophys. J. 66 (1994) 345-354
42. + channels by protein kinase A requires actin filaments. Am. J. Physiol. 265 (1993) C224-C233
43. + channel. J. Biol. Chem. 271 (1996) 7879-7882
44. + and water transport in the rat CCD. Am. J. Physiol. 265 (1993) F569-F577
45. Sariban-Sohraby S., and Benos D.J. Detergent solubilization, functional reconstitution, and partial purification of an epithelial amiloride-binding protein. Biochemistry 25 (1986) 4639-4640
46. + channel protein following vasopressin treatment of A6 cells. J. Biol. Chem. 263 (1988) 13875-13879
47. Schild L., Canessa C.M., Shimkets R.A., Gautschi I., Lifton R.P., and Rossier B.C. A mutation in the epithelial sodium channel causing Liddle disease increases channel activity in the Xenopus laevis oocyte expression system. Proc. Natl. Acad. Sci.U.S.A. 92 (1995) 5699-5703
48. Schild L., Lu Y., Gautschi I., Schneeberger E., Lifton R.P., and Rossier B.C. Identification of a PY motif in the epithelial Na channel subunits as a target sequence for mutations causing channel activation found in Liddle syndrome. EMBO J. 15 (1996) 2381-2387
49. Schild L., Schneeberger E., Gautschi I., and Firsov D. Identification of amino acid residues in the α, β, and γ subunits of the epithelial sodium channel (ENaC) involved in amiloride block and ion permeation. J. Gen. Physiol. 109 (1997) 15-26
50. Shimkets R.A., Warnock D.G., Bositis C.M., Williams C.N., Hansson J.H., Schamelan M., Gill J.R.J., Ulick S., Milora R.V., Findling J.W., Canessa C.M., Rossier B.C., and Lifton R.P. Liddle's syndrome: Heritable human hypertension caused by mutations in the β subunit of the epithelial sodium channel. Cell (Cambridge, Mass.) 79 (1994) 407-414
51. Shimkets R.A., Lifton R., and Canessa C.M. In vitro phosphorylation of the epithelial sodium channel. Proc. Natl. Acad. Sci. U.S.A. 95 (1998) 3301-3305
52. Silver R.B., Frindt G., Windhager E.E., and Palmer L.G. Feedback regulation of Na channels in rat CCT. I. Effects of inhibition of the Na pump. Am. J. Physiol. 264 (1993) F557-F564
53. Snyder P.M., McDonald F.J., Stokes J.B., and Welsh M.J. Membrane topology of the amiloride-sensitive epithelial sodium channel. J. Biol. Chem. 269 (1994) 24379-24383
54. + channel. Cell (Cambridge, Mass.) 83 (1995) 969-978
55. Snyder P.M., Cheng Prince C., Rogers L.S.J.C., and Welsh M.J. Electrophysiological and biochemical evidence that DEG/ENaC cation channels are composed of nine subunits. J. Biol. Chem. 273 (1998) 681-684
56. Sorscher E.J., Accavitti M.A., Keeton D., Steadman E., Frizzell R.A., and Benos D.J. Antibodies against purified epithelial sodium channel protein from bovine renal papilla. Am. J. Physiol. 255 (1988) C835-C843
57. Stanton B.A., Chalfant M.L., Ismailov I.I., Karlson K., Loffing D., Halpin P., Berdiev B.K., Fuller C.M., Shlyonsky V.G., and Benos D.J. Regulation of ENaC by the amino terminus of α-rENaC. Physiologist 40 (1997) A-4 (abstr. 4.5)
58. + channel deleted in Liddle's syndrome. EMBO J. 15 (1996) 2371-2380
59. Stutts M.J., Canessa C.M., Olsen Hamrick J.C., Cohn M.J.A., Rossier B.C., and Boucher R.C. CFTR as a cAMP-dependent regulator of sodium channels. Science 269 (1995) 847-850
60. Stutts M.J., Rossier B.C., and Boucher R.C. CFTR inverts PKA-mediated regulation of epithelial sodium channel single channel kinetics. J. Biol. Chem. 272 (1997) 14037-14040
61. Tamba K., Tucker J.K., Ma H., Saxena S., Unlap T., Quick M., Oh Y., and Warnock D.G. Human ENaC expressed in Xenopus oocytes is activated by cyclic AMP. FASEB J. 12 (1998) A372 (abstr. 2161)
62. + channel gene. J. Clin. Invest. 97 (1996) 1780-1784
63. Tousson A., Alley C.D., Sorscher E.J., Brinkley B.R., and Benos D.J. Immuno-chemical localization of amiloride-sensitive sodium channels in sodium transporting epithelia. J. Cell Sci. 93 (1989) 349-362
64. + channel function. J. Biol. Chem. 270 (1995) 11735-11737
65. + channel. J. Biol. Chem. 270 (1995) 27411-27414
66. Yanase M., and Handler J.S. Activators of protein kinase C inhibit sodium transport in A6 epithelia. Am. J. Physiol. 250 (1986) C517-C522
67. Zagotta W.N., Hoshi T., and Aldrich R.W. Restoration of inactivation in mutants of Shaker potassium channels by a peptide derived from ShB. Science 250 (1990) 568-571