High-molecular weight hyaluronan reduced renal PKC activation in genetically diabetic mice

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1802, Issue 11, 2010, Pages 1118-1130

  Campo, Giuseppe M ^a   Avenoso, Angela ^a   Micali, Antonio ^a   Nastasi, Giancarlo ^a   Squadrito, Francesco ^a   Altavilla, Domenica ^a   Bitto, Alessandra ^a   Polito, Francesca ^a   Rinaldi, Maria Grazia ^a   Calatroni, Alberto ^a   D'Ascola, Angela ^a   Campo, Salvatore ^a  

^a UNIVERSITY OF MESSINA   (Italy)

Author keywords

CD44; Cytokines; Diabetes; Hyaluronan; NF B; PKC

Indexed keywords

HERMES ANTIGEN; HYALURONIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INSULIN; INTERLEUKIN 18; INTERLEUKIN 6; ISOENZYME; MATRILYSIN; MATRIX METALLOPROTEINASE; MESSENGER RNA; PROTEIN KINASE C; PROTEIN KINASE C ALPHA; PROTEIN KINASE C BETA; PROTEIN KINASE C EPSILON; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIABETIC NEPHROPATHY; ENZYME ACTIVATION; GENE EXPRESSION; HISTOPATHOLOGY; INSULIN BLOOD LEVEL; LIGAND BINDING; MALE; MOLECULAR WEIGHT; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; ANTIGENS, CD44; BLOOD GLUCOSE; BLOTTING, WESTERN; DIABETES MELLITUS; DIABETIC NEPHROPATHIES; ENZYME ACTIVATION; HYALURONIC ACID; INTERLEUKIN-18; INTERLEUKIN-6; KIDNEY; MALE; MATRIX METALLOPROTEINASE 7; MICE; MICE, CONGENIC; MOLECULAR WEIGHT; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; PROTEIN KINASE C; PROTEIN KINASE C-EPSILON; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR NECROSIS FACTOR-ALPHA;

MUS;

EID: 77956649315     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbadis.2010.08.004     Document Type: Article

References (56)

1. Zelmanovitz T., Gerchman F., Balthazar A.P., Thomazelli F.C., Matos J.D., Canani L.H. Diabetic nephropathy. Diabetol. Metab. Syndr. 2009, 1:1-17.
2. Tervaert T.W., Mooyaart A.L., Amann K., Cohen A.H., Cook H.T., Drachenberg C.B., Ferrario F., Fogo A.B., Haas M., Heer E.D., Joh K., Noel L.H., Radhakrishnan J., Seshan S.V., Bajema I.M., Bruijn J.A. Pathological classification of diabetic nephropathy. J Am Soc Nephrol 2010, 21:556-563.
3. Navarro-Gonzales J.F., Mora-Fernandez C. The role of inflammatory cytokines in diabetic nephropathy. J Am Soc Nephrol 2008, 19:433-442.
4. Wu C.C., Chen J.S., Lu K.C., Chen C.C., Lin S.H., Chu P., Sytwu H.K., Lin Y.F. Aberrant cytokines/chemokines production correlate with proteinuria in patients with overt diabetic nephropathy. Clin Chim Acta 2010, 411:700-704.
5. Hakim F.A., Pflueger A. Role of oxidative stress in diabetic kidney disease. Med Sci Monit 2010, 16. RA37-48.
6. Nvarro-Gonzales J.F., Jarque A., Muros M., Mora C., Garcia J. Tumor necrosis factor-alpha as a therapeutic target for diabetic nephropathy. Cytokine Growth Factor Rev 2009, 20:165-173.
7. Goldberg R.B. Cytokine and cytokine-like inflammation markers, endothelial dysfunction, and imbalanced coagulation in development of diabetes and its compications. J Clin Endocrinol Metab 2009, 94:3171-3182.
8. Miyauchi K., Takiyama Y., Honjyo J., Tateno M., Haneda M. Upregulated IL-18 expression in type 2 diabetic subjects with nephropathy: TGF-β1 enhanced IL-18 expression in human renal proximal tubular epithelial cells. Diabetes Res. Clin. Pract. 2009, 83:190-199.
9. Xiao H., Li Y., Qi J., Wang H., Liu K. Peroxynitrite plays a key role in glomerular lesions in diabetic rats. J Nephrol 2009, 22:800-808.
10. Thrailkill K.M., Bunn R.C., Fowlkes J.L. Matrix metalloproteinases: their potential role in the pathogenesis of diabetic nephropathy. Endocr 2009, 35:1-10.
11. Okada S., Saito M., Kazuyama E., Hanada T., Kawaba Y., Hayashi A., Satoh K., Kanzaki S. Effects of N-hexacosanol on nitric oxide synthase system in diabetic rat nephropathy. Mol Cell Biochem 2008, 315:169-177.
12. Gruden G., Perin P.C., Camussi G. Insight on the pathogenesis of diabetic nephropathy from the study of podocyte and mesangial cell biology. Curr. Diabetes Rev. 2005, 1:27-40.
13. Nagy G., Koncz A., Fernandez D., Perl A. Nitric oxide, mitochondrial hyperpolarization, and T cell activation. Free Radic Biol Med 2007, 42:1625-1631.
14. Han K.H., Han S.Y., Kim H.S., Kang Y.S., Cha D.R. Prolonged administration enhanced the renoprotective effect of pentoxifylline via anti-inflammatory activity in streptozotocin-induced diabetic nephropathy. Inflammation 2010, 33:137-143.
15. Li J.J., Lee S.H., Kim D.K., Jin R., Jung D.S., Kwak S.J., Kim S.H., Han S.H., Lee J.E., Moon S.J., Ryu D.R., Yoo T.H., Han D.S., Kang S.W. Colchicine attenuates inflammatory cell infiltration and extracellular matrix accumulation in diabetic nephropathy. Am. J. Physiol. Renal Physiol. 2009, 297:F200-F209.
16. Fraser J.R., Laurent T.C., Laurent U.B. Hyaluronan: its nature, distribution, function and turnover. J Intern Med 1997, 242:27-33.
17. Noble P.W. Hyaluronan and its catabolic products in tissue injury and repair. Matrix Biol 2002, 21:25-29.
18. Jiang D., Liang J., Noble P.W. Hyaluronan in tissue injury and repair. Annu Rev Cell Dev Biol 2007, 23:435-461.
19. Campo G.M., Avenoso A., Campo S., D'Ascola A., Traina P., Calatroni A. Differential effect of molecular size HA in mouse chondrocytes stimulated with PMA. Biochim Biophys Acta 2009, 1790:1353-1367.
20. Campo G.M., Avenoso A., Campo S., D'Ascola A., Nastasi G., Calatroni A. Molecular size hyaluronan differently modulates toll-like receptor-4 in LPS-induced inflammation in mouse chondrocytes. Biochimie 2010, 92:204-215.
21. Aruffo A., Stamenkovic I., Melnick M., Underhill C.B., Seed B. CD44 is the principal cell surface receptor for hyaluronate. Cell 1990, 61:1303-1313.
22. Heldin P., Karousou E., Bernert B., Porsch H., Nishitsuka K., Skandalis S.S. Importance of hyaluronan-CD44 interactions in inflammation and tumorigenesis. Connect Tissue Res 2008, 49:215-218.
23. Weiss L., Slavin S., Reich S., Cohen P., Shuster S., Stern R., Kaganovsky E., Okon E., Rubinstein A.M., Naor D. Induction of resistance to diabetes in non-obese diabetic mice by targeting CD44 with a specific monoclonal antibody. Proc Natl Acad Sci USA 2000, 97:285-290.
24. Weiss L., Botero-Anug A.M., Hand C., Slavin S., Naor D. CD44 gene vaccination for insulin-dependent diabetes mellitus in non-obese diabetic mice. Isr Med Assoc J 2008, 10:20-25.
25. Zoller M., Gupta P., Marhaba R., Vitacolonna M., Freyschmidt-Paul P. Anti-CD44-mediated blockade of leukocyte migration in skin-associated immune diseases. J Leukoc Biol 2007, 82:57-71.
26. Baier G., Wagner J. PKC inhibitors: potential in T cell-dependent immune diseases. Curr Opin Cell Biol 2009, 21:262-267.
27. Thorne R.F., Legg J.W., Isacke C.M. The role of the CD44 transmembrane and cytoplasmic domains in co-ordinating adhesive and signalling events. J Cell Sci 2004, 117:373-380.
28. Larsson C. Protein kinase C and the regulation of the actin cytoskeleton. Cell Signal 2006, 18:276-284.
29. Okamoto I., Kawano Y., Matsumoto M., Suga M., Kaibuchi K., Andò M., Saya H. Regulated CD44 cleavage under the control of protein kinase C, calcium influx, and the Rho family of small G proteins. J Biol Chem 1999, 274:25525-25534.
30. Liu D., Liu T., Li R., Sy M.S. Mechanisms regulating the binding activity of CD44 to hyaluronic acid. Front Biosci 1998, 3:d631-d636.
31. Fitzgerald K.A., Bowie A.G., Skeffington B.S., O'Neill L.A.J. Ras, protein Kinase Czeta and IkB kinase 1 and 2 are downstream effectors of CD44 during the activation of NF.kB by hyaluronic acid fragments in T-24 carcinoma cells. J Immunol 2000, 164:2053-2063.
32. Kumar A., Takada Y., Boriek A.M., Aggarwal B.B. Nuclear factor-kappaB: its role in health and disease. J Mol Med 2004, 82:434-448.
33. Menne J., Meier M., Park J.K., Boehne M., Kirsch T., Lindschau C., Ociepka R., Leitges M., Rinta-Valkama J., Holthofer H., Haller H. Nephrin loss in experimental diabetic nephropathy is prevented by deletion of protein kinase C alpha signalling in-vivo. Kidney Int 2006, 70:1456-1462.
34. Wu D., Peng F., Zhang B., Ingram A.J., Kelly D.J., Gilbert R.E., Gao B., Krepinsky J.C. PKC-beta1 mediates glucose-induced Akt activation and TGF-beta1 upregulation in mesangial cells. J Am Soc Nephrol 2009, 20:554-566.
35. Nagareddy P.R., Soliman H., Lin G., Rajput P.S., Kumar U., McNeill J.H., MacLeod K.M. Selective inhibition of protein kinase C beta (2) attenuates inducible nitric oxide synthase-mediated cardiovascular abnormalities in streptozotocin-induced diabetic rats. Diabetes 2009, 58:2355-2364.
36. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976, 72:248-254.
37. Garris D.R., Garris B.L. Estrogenic restoration of functional pancreatic islet cytoarchitecture in diabetes (db/db) mutant C57BL/KsJ mice: relationship to estradiol localization, systemic glycemia, and persistent hyperinsulinemia. Cell Tissue Res 2005, 319:231-242.
38. Lebel L., Fraser J.R., Kimpton W.S., Gabrielsson J., Gerdin B., Laurent T.C. A pharmacokinetic model of intravenously administered hyaluronan in sheep. Pharm Res 1989, 6:677-682.
39. Naor D., Nedvetzki S., Walmsley M., Yayon A., Turley E.A., Golan I., Caspi D., Sebban L.E., Zick Y., Garin T., Karussis D., Assayag-Asherie N., Raz I., Weiss L., Slavin S., Golan I. CD44 involvement in autoimmune inflammations: the lesson to be learned from CD44-targeting by antibody or from knockout mice. Ann. N.Y. Acad. Sci. 2007, 1110:233-247.
40. Melin J., Hellberg O., Funa K., Hallgren R., Larsson E., Fellstrom B.C. Ischemia-induced renal expression of hyaluronan and CD44 in diabetic rats. Nephron Exp Nephrol 2006, 103:e86-e94.
41. Lan H.Y. Role of macrophage migration inhibition factor in kidney disease. Nephron Exp Nephrol 2008, 109:e79-e83.
42. Ascon M., Ascon D.B., Liu M., Cheadle C., Sarkar C., Racusen L., Hassoun H.T., Rabb H. Renal ischemia-reperfusion leads to long term infiltration of activated and effector-memory T lymphocytes. Kidney Int 2009, 75:526-535.
43. Newton A.C. Regulation of the ABC kinases by phosphorylation: protein kinase C as a paradigm. Biochem J 2003, 370:361-371. part2).
44. Martelli A.M., Evangelisti C., Nyakern M., Manzoli F.A. Nuclear protein kinase C. Biochim Biophys Acta 2006, 1761:542-551.
45. Newton A.C. Lipid activation of protein kinases. J. Lipid Res. Suppl 2009, 50:S266-S271.
46. Koya D., Haneda M., Nakagawa H., Isshiki K., Sato H., Maeda S., Sugimoto T., Yasuda H., Kashiwagi A., Ways D.K., King G.L., Kikkawa R. Amelioration of accelerated diabetic mesangial expansion by treatment with a PKC β inhibitor in diabetic db/db mice, a rodent model for type 2 diabetes. FASEB J 2000, 14:439-447.
47. Kim Y., Lee Y.S., Choe J., Lee H., Kim Y.M., Joung D. CD44-epidermal growth factor receptor interaction mediates hyaluronic acid-promoted cell motility by activating protein kinase C signalling involving Akt, Rac1, Phox, reactive oxygen species, focal adhesion kinase, and MMP-2. J Biol Chem 2008, 283:22513-22528.
48. Jensen P.V., Larsson L.I. Actin microdomains on endothelial cells: association with CD44, ERM proteins, and signalling molecules during quiescence and wound healing. Histochem Cell Biol 2004, 121:361-369.
49. Clarke D.L., Sutcliffe A., Deacon K., Bradbury D., Corbett L., Knox A.J. PKCbetaII augments NF-kappaB-dependent transcription at the CCL11 promoter via p300/CBP-Associated factor recruitment and histone H4 acetylation. J Immunol 2008, 181:3503-3514.
50. Thylur R.P., Kim Y.D., Kwon M.S., Oh H.M., Kwon H.K., Kim S.H., Im S.H., Chun J.S., Park Z.Y., Jun C.D. Swiprosin-1 is expressed in mast cells and up-regulated through the protein kinase C beta I/eta pathway. J Cell Biochem 2009, 108:705-715.
51. Greene M.W., Ruhoff M.S., Burrington C.M., Garofalo R.S., Orena S.J. TNFalpha activation of PKCdelta, mediated by NFkappaB and ER stress, cross-talks with the insulin signalling cascade. Cell Signal 2010, 22:274-284.
52. Yates E.A., Terry C.J., Rees C., Rudd T.R., Duchesne L., Skidmore M.A., Lèvy R., Thanh N.T., Nichols R.J., Clarke D.T., Fernig D.G. Protein-GAG interactions: new surface-based techniques, spectroscopies and nanotechnology probes. Biochem Soc Trans 2006, 34:427-430.
53. Steeber D.A., Venturi G.M., Tedder T.F. A new twist to the leukocyte adhesion cascade: intimate cooperation is key. Trends Immunol 2005, 26:9-12.
54. Eberlein M., Scheibner K.A., Black K.E., Collins S.L., Chan-Li Y., Powell J.D., Horton M.R. Anti-oxidant inhibition of hyaluronan fragment-induced inflammatory gene expression. J Inflamm 2008, 5:5-20.
55. Stern R. Hyaluronan catabolism: a new metabolic pathway. Eur J Cell Biol 2004, 83:317-325.
56. Beckman J.A., Goldfine A.B., Gordon M.B. L. A Garrett, M.A. Creager, Inhibition of protein kinase Cβ prevents impaired endothelium-dependent vasodilation caused by hyperglycemia in humans. Circ Res 2002, 90:107-111.