Alcohol-induced deterioration in primary antioxidant and glutathione family enzymes reversed by exercise training in the liver of old rats

Alcohol

Volumn 44, Issue 6, 2010, Pages 523-529

  Mallikarjuna, K ^a,b   Shanmugam, K R ^a   Nishanth, K ^c   Wu, Ming Chieh ^b   Hou, Chien Wen ^b   Kuo, Chia Hua ^b   Reddy, K Sathyavelu ^a  

^a SRI VENKATESWARA UNIVERSITY   (India)

^b UNIVERSITY OF TAIPEI   (Taiwan)

^c NEW JERSEY INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Aging liver; Ethanol; Exercise; Free radical scavenging enzymes; Oxidative stress; ROS

Indexed keywords

CATALASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; SELENIUM DERIVATIVE; SUPEROXIDE DISMUTASE;

AGING; ALCOHOL CONSUMPTION; ALCOHOL METABOLISM; ALCOHOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; EXERCISE; GLUTATHIONE METABOLISM; LIVER; MALE; NONHUMAN; OXIDATIVE STRESS; PROTEIN BLOOD LEVEL; PROTEIN DETERMINATION; RAT; WISTAR RAT;

AGING; ANIMALS; ANTIOXIDANTS; CATALASE; ETHANOL; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; LIVER; LIVER DISEASES, ALCOHOLIC; MALE; OXIDATIVE STRESS; PHYSICAL CONDITIONING, ANIMAL; RATS; RATS, WISTAR; SUPEROXIDE DISMUTASE;

RATTUS;

EID: 77956649283     PISSN: 07418329     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.alcohol.2010.07.004     Document Type: Article

References (42)

1. Aebi H. Catalase. Meth. Enzymol. 1984, 105:125-126.
2. Ardies C.M., Zachman E.K., Koehn B. Effects of swimming exercise and ethanol on rat liver P450-dependent monoxygenases. Med. Sci. Sports Exer. 1994, 26:1453-1458.
3. Bailey S.M., Patel V.B., Young T.A., Asayama K., Cunningham C.C. Chronic ethanol consumption alters the glutathione/glutathione peroxidase-1 system and protein oxidation status in rat liver. Alcohol. Clin. Exp. Res. 2001, 25:726-733.
4. Bindu M.P., Sreekanth K.S., Annamali P.T., Augusti K.T. Effect of S-allyl cysteine sulphoxide on lipid metabolism and free radical scavengers in alcohol-fed rats. Curr. Sci. 2002, 82:628-631.
5. Cahill A., Hershman S., Davies A., Sykora P. Ethanol feeding enhances age-related deterioration of the rat hepatic mitochondrion. Am. J. Physiol. Gastrointest. Liver Physiol. 2005, 289:G1115-G1123.
6. Carlberg I., Mannervik B. Glutathione reductase. Meth. Enzymol. 1985, 113:484-499.
7. Chandra R., Aneja R., Rewal C., Konduri R., Das S.K., Agarwal S. An opium alkaloid-papaverine ameliorates ethanol-induced hepatotoxicity: diminution of oxidative stress. Ind. J. Clin. Biochem. 2000, 15:155-160.
8. Das S.K., Vasudevan D.M. Effect of ethanol on liver antioxidant defense system: a dose dependent study. Ind. J. Clin. Biochem. 2005, 20:80-84.
9. Duncan K., Harris S., Ardies C.M. Running exercise may reduce risk of lung and liver cancer by inducing activity of antioxidant and phase II enzymes. Cancer Lett. 1997, 116:151-158.
10. El-Sayed M.S., Ali N., El-Sayed A.Z. Interaction between alcohol and exercise: physiological and haematological implications. Sports Med. 2005, 35:257-269.
11. Flohe L., Gunzler W.A. Glutathione peroxidase. Meth. Enzymol. 1984, 105:115-121.
12. Gunduz F., Senturk U.K., Kuru O., Aktekin B., Aktekin M.R. The effect of one year's swimming exercise on oxidant stress and antioxidant capacity in aged rats. Physiol. Res. 2004, 53:171-176.
13. Gupta S., Pandey R., Katyal R., Aggarwal H.K., Aggarwal R.P., Aggarwal S.K. Lipid peroxidation levels and antioxidant status in alcoholic liver disease. Ind. J. Clin. Biochem. 2003, 20:67-71.
14. Habig W.H., Pabst M.J., Jacoby W.B. Glutathione S-transferase: the enzymatic step in mercapturic acid formation. J. Biol. Chem. 1984, 249:7130-7139.
15. Hirano T., Kaplowitz N., Tsukamoto H., Kamimura S., Fernandez-Checa J.C. Hepatic mitochondrial glutathione depletion and progression of experimental alcoholic liver disease in rats. Hepatology 1992, 16:1423-1427.
16. Husain K., Somani S.M. Interaction of exercise training and chronic ethanol ingestion on hepatic and plasma antioxidant system in rat. J. Appl. Toxicol. 1997, 17:189-194.
17. Husain K., Somani S.M. Interaction of exercise and ethanol on hepatic and plasma antioxidant system in rat. Pathophysiology 1997, 4:69-74.
18. Indira S.K., Jhansi L.C.H. Endurance exercise-induced alterations in antioxidant enzymes of old albino male rats. Curr. Sci. 2001, 80:921-923.
19. Jang I., Chae K., Cho J. Effects of age and strain on small intestinal and hepatic antioxidant defense enzymes in Wistar and Fisher 344 rats. Mech. Ageing Dev. 2001, 122:561-570.
20. Jurczuk M., Moniuszko-Jakoniuk J., Rogalska J. Glutathione-related enzyme activity in liver and kidney of rats exposed to cadmium and ethanol. Polish J. Environ. Stud. 2006, 15:861-868.
21. Kato S., Kawase T., Alderman J., Inatomi N., Lieber C.S. Role of xanthine oxidase in ethanol-induced lipid peroxidation in rats. Gastroenterology 1990, 98:203-210.
22. Kim Y.C., Kim Y.S., Sohn Y.R. Effect of age increase on metabolism and toxicity of ethanol in female rats. Life Sci. 2003, 74:509-519.
23. Knecht K.T., Thurman R.G., Mason R.P. Role of superoxide and trace transition metals in production of α-hydroxylethyl radical from ethanol by microsomes from alcohol dehydrogenase-deficient deermice. Arch. Biochem. Biophys. 1993, 303:339-348.
24. Kumaran S.V., Arulmathi K., Srividhya R., Kalaiselvi P. Repletion of antioxidant status by EGCG and retardation of oxidative damage induced macromolecular anomalies in aged rats. Exp. Gerontol. 2008, 43:176-183.
25. Mallikarjuna K., Nishanth K., Reddy K.S. Hepatic glutathione mediated antioxidant system in ethanol treated rats: decline with age. Pathophysiology 2007, 14:17-21.
26. Mallikarjuna K., Nishanth K., Hou C.W., Kuo C.H., Reddy K.S. Effect of exercise training on ethanol-induced oxidative damage in aged rats. Alcohol 2009, 43:59-64.
27. Meir P., Seitz H.K. Age, alcohol metabolism and liver disease. Curr. Opin. Clin. Nutr. Metab. Care 2008, 11:21-26.
28. Misra H.P., Fridovich I. The role of superoxide anion in the autooxidation of epinephrine and a simple assay for superoxide dismutase. J. Biol. Chem. 1972, 247:3170-3175.
29. Oh S.I., Kim C.I., Chun H.J., Park S.C. Chronic ethanol consumption affects glutathione status in rat liver. J. Nutr. 1997, 128:758-763.
30. Ojeda M.L., Nogales F., Vazquez B., Delgado M.J., Murillo M.L., Carreras O. Alcohol, gestation and breastfeeding: selenium as an antioxidant therapy. Alcohol Alcohol. 2009, 44:272-277.
31. Pigeolet E., Corbisier P., Houbion A., Lambert D., Michiels C., Raes M., et al. Glutathione peroxidase, superoxide dismutase and catalase inactivation by peroxides and oxygen derived free radicals. Mech. Ageing Dev. 1990, 51:283-297.
32. Polavarapu R., Spitz D.R., Sim J.E., Follansbee N.H., Oberley L.W., Rahemtulla A., et al. Increased lipid peroxidation and impaired antioxidant enzyme function is associated with pathological liver injury in experimental alcoholic liver disease in rats fed diets high in corn oil and fish oil. Hepatology 1998, 27:1317-1323.
33. Reddy C.C., Tu C.P., Burgess J.R., Ho C.Y., Scholz R.W., Massarro E.J. Evidence for the occurrence of selenium-independent glutathione peroxidase in rat liver microsomes. Biochem. Biophys. Res. Commun. 1981, 101:970-978.
34. Rikans L.E., Snowden C.D., Moore D.R. Influence of aging on ethanol and acetaldehyde oxidation in female rat liver. Gerontology 1990, 36:185-192.
35. Rushmore T.H., Morton M.R., Pickett C.B. The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity. J. Biol. Chem. 1991, 266:11632-11659.
36. Savarino L., Granchi D., Ciapetti G., Cenni E., Ravaglia G., Forti P., et al. Serum concentrations of zinc and selenium in elderly people: results in healthy nonagenarians/centenarians. Exp. Gerontol. 2001, 36:327-339.
37. Seitz H.K., Xu Y., Simanowski U.A., Osswald B. Effect of age and gender on in vivo ethanol elimination, hepatic alcohol dehydrogenase activity, and NAD availability in F344 rats. Res. Exp. Med. (Berl.) 1992, 192:205-212.
38. Sen C.K., Marin E., Kretzschmar M., Hanninen O. Skeletal muscle and liver glutathione homeostasis in response to training, exercise, and immobilization. J. Appl. Physiol. 1992, 73:1265-1272.
39. Skrzydlewska E., Augustyniak A., Michalak K., Farbiszewski R. Green tea supplementation in rats of different ages mitigates ethanol-induced changes in brain antioxidant abilities. Alcohol 2005, 37:89-98.
40. Somani S.M., Ryback L.P. Comparative effects of exercise training on transcription of antioxidant enzyme and the activity in old rat heart. Ind. J. Physiol. Pharmacol. 1996, 40:205-212.
41. Suter P.M., Schutz Y., Jequier E. The effect of ethanol on fat storage in healthy subjects. N. Engl. J. Med. 1992, 326:983-987.
42. Zima T., Fialova L., Mestek O., Janebova M., Crkovska J., Malbohan I., et al. Oxidative stress, metabolism of ethanol and alcohol-related diseases. J. Biomed. Sci. 2001, 8:59-70.