Effect of ethanol on liver antioxidant defense systems: A dose dependent study

Indian Journal of Clinical Biochemistry

Volumn 20, Issue 1, 2005, Pages 80-84

  Das, Subir Kumar ^a   Vasudevan, D M ^a  

^a AMRITA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Antioxidants; Ethanol; Glutathione; Oxidative stress; Superoxide dismutase

Indexed keywords

ALCOHOL; ASCORBIC ACID; CATALASE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SUPEROXIDE; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ADIPOSE TISSUE; ALCOHOL CONSUMPTION; ALCOHOL METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ACTIVITY; LIPID PEROXIDATION; LIVER METABOLISM; LIVER WEIGHT; MALE; NONHUMAN; OXIDATIVE STRESS; RAT; WEIGHT GAIN;

ANIMALIA;

EID: 14944359241     PISSN: 09701915     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02893047     Document Type: Article

References (24)

1. Das, S.K., Nayak, P., and Vasudevan, D.M. (2003) Biochemical markers for alcohol consumption. Ind. J. Clin. Biochem. 18(2), 111-118.
2. Ishii, H., Kurose, I., and Kato, S. (1997) Pathogenesis of alcoholic liver disease with particular emphasis on oxidative stress. J. Gastroenterol. Hepatol. 12(9-10), S272-282
3. Fernandez-Checha, J.C., Kaplowitz, N., Colell, A., and Gracia-Ruiz, C. (1997) Oxidative stress and alcoholic liver disease. Alcohol Health & Res. World. 21(4), 321-324
4. Dinu, V. and Zamfir, O. (1991) Oxidative stress in ethanol intoxicated rats. Rev. Roum. Physiol. 28(1-2), 63-67.
5. Chandra, R., Aneja, R., Rewal, C., Konduri, R., Dass, S.K., and Agarwal, S. (2000) An opium alkaloid-Papaverine ameliorates ethanol-induced hepatotoxicity: diminution of oxidative stress. Ind. J. Clin. Biochem. 15(2), 155-160.
6. Husain, K., Scott, B.R., Reddy, S.K., and Somani, S.M. (2001) Chronic ethanol and nicotine interaction on rat tissue antioxidant defense system. Alcohol. 25(2), 89-97.
7. Oh, S.I., Kim, C.I., Chun, H.J., and Park, S.C. (1998) Chronic ethanol consumption affects glutathione status in rat liver. J. Nutr. 128(4), 758-763
8. Chatterjee, A.K., Sadhu, U., Dalal, B.B., Chatterjee, T. (1984) Studies on certain drug metabolising enzymes in deoxypyridoxin treated rats. Jap. J. Pharmacol. 25, 827.
9. Lowry, O.H., Rosenbourgh, N.J., Farr, A.L., and Randall, R.J. (1951) Protein measurement with folin phenol reagent. J. Biol. Chem. 193, 265-275.
10. Roe, J.H., and Kuether, C.A. (1943) The determination of ascorbic acid in whole blood and urine through the 2,4-dinitrophenyl hydrazine derivative of dehydro ascorbic acid. J. Biol. Chem. 147, 399-401.
11. Sinnhuber, R.O., Yu, T.C., and Yu, T.C. (1958) Characterization of the red pigment formed in the thiobarbituric acid determination of oxidative rancidity. Food Res. 23, 626-630.
12. Ellman, G.L. (1959) The sulphydryl groups. Arch. Biochem. Biophys. 32, 70-77.
13. Beers, R.F., and Sizer, I.W. (1952) A spectrophotometric method for measuring the breakdown of hydrogen peroxides by catalase. J. Biol. Chem. 195, 133-140.
14. rd edn. pp. 258-265.
15. Habig, W.H., Pabst, M.J., and Jakoby, W.B. (1974) Glutathione S-transferase, the first enzymatic step in mercapturic acid formation. J. Biol. Chem. 249, 7130-7139.
16. Paglia, D.E., and Valentine, W.N. (1967) Studies on the quantitative and qualitative characterisation of erythrocyte glutathione peroxides. J. Lab. Clin. Med. 70, 158-159.
17. Marklund, S., and Marklund, G. (1974) Involvement of superoxide radical in the auto oxidation pyrogallol and a convenient assay for superoxide dismutase. Eur. J. Biochem. 47, 469-474.
18. Beutler, E. (1988) Glucose-6-phosphate dehydrogenas - New perspectives. Blood. 73, 1397.
19. Husain, K., and Somani, S.M. (1997) Interaction of exercise training and chronic ethanol ingestion on hepatic and plasma antioxidant system in rat. J. Appl. Toxicol. 17(3), 189-194.
20. McCord, J.M. (1979) Superoxide dismutase. In: Isozyme: Current topics in biological and medica research, Eds, Tattazzi, M.C., Scanalios, J.G., Whitt, G.S. and Alan, R. Liss Inc. New York, section 1.
21. Marklund, S. (1984) Properties of extracellular superoxide dismutase from human lung. Biochem. J. 220, 269-272.
22. Fridovich, I. (1999) Superoxide dismutases. J. Biol. Chem. 264, 7761-7764.
23. Koch, O., Farre, S., De Leo, M.E., Palozza, P., Palazzotti, B., Borrelo, S., Palombini, G., Cravero, A., and Galeotti, T. (2000) Regulation of manganese superoxide dismutase (MnSOD) in chronic experimental alcoholism: effects of vitamin E-supplemented and -deficient diets. Alcchol Alcohol. 35(2), 159-163.
24. Aniya, Y., and Daido, A. (1994) Activation of microsomal glutathione S-transferase in tert-butyl hydroperoxide-induced oxidative stress of isolated rat liver. Jpn. J. Pharmacol. 66(1), 123-130