CD8- and CD95/95L-dependent mechanisms of resistance in mice with chronic pulmonary tuberculosis

American Journal of Respiratory Cell and Molecular Biology

Volumn 24, Issue 2, 2001, Pages 203-209

  Turner, J ^a   D'Souza, C D ^a   Pearl, J E ^a   Marietta, P ^a   Noel, M ^a   Frank, A A ^a   Appelberg, R ^a   Orme, I M ^a   Cooper, A M ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA; BACTERIA (MICROORGANISMS); MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS;

EID: 0035125898     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.24.2.4370     Document Type: Article

References (35)

1. Progression of chronic pulmonary tuberculosis in mice aerogenically infected with virulent Mycobacterium tuberculosis
2. Granuloma formation is required to contain bacilli growth and delay mortality in mice chronically infected with Mycobacterium tuberculosis
3. Cytokine/chemokine cascades in immunity to tuberculosis
4. Mice deficient in CD4 T cells have only transiently diminished levels of IFN-gamma, yet succumb to tuberculosis
5. Adult tuberculosis overview: African versus Western perspectives
6. The kinetics of emergence and toss of mediator T lymphocytes acquired in response to infection with Mycobacterium tuberculosis
7. T lymphocytes mediating protection and cellular cytolysis during the course of Mycobacterium tuberculosis infection: Evidence for different kinetics and recognition of a wide spectrum of protein antigens
8. Major histocompatibility complex class I-restricted T cells are necessary for protection against Mycobacterium tuberculosis in mice
9. Susceptibility of mice deficient in CD1d or Tap1 to infection with Mycobacterium tuberculosis
10. A novel non-classical β2-microglobulin-restricted mechanism influencing early lymphocyte accumulation and subsequent resistance to tuberculosis in the lung
11. Relative contributions of distinct MHC class I-dependent cell populations in protection to tuberculosis infection in mice
12. + T cells requires the production of gamma interferon
13. Increase in gamma interferon-secreting CD8, as well as CD4, T cells in lungs following aerosol infection with Mycobacterium tuberculosis
14. Human cytolytic and interferon gamma-secreting CD8 T lymphocytes specific for Mycobacterium tuberculosis
15. Impaired resistance to Mycobacterium tuberculosis infection after selective in vivo depletion of L3T4+ and Lyt-2+ T cells
16. Differential effects of cytolytic T cell subsets on intracellular infection
17. Human alveolar T lymphocyte responses to Myeobacterium tuberculosis antigens: Role for CD4 and CD8 cytotoxic T cells and relative resistance of alveolar macrophages to lysis
18. Stimulation of human peripheral blood mononuclear cells with live Mycobacterium bovis BCG activates cytolytic CD8+ T cells in vitro
19. + T cell-mediated protection against an intracellular bacterium by perforin-dependent cytotoxicity
20. The antimicobial activity of cytolytic T cells is mediated by granulysin
21. Drug-resistant strains of Mycobacterium tuberculosis exhibit a range of virulence for mice
22. Expression of memory immunity in the lung following re-exposure to Mycobacterium tuberculosis
23. The immunopathogenesis of tuberculosis: A new working hypothesis
24. Helper T cells without CD4: Control of leishmaniasis in CD4-deficient mice
25. CD8+ T lymphocytes in intracellar microbial infections
26. Molecular mechanisms of lymphocyte-mediated cytotoxicity and their role in immunological protection and pathogenesis in vivo
27. The course of Mycobacterium tuberculosis infection in the lungs of mice lacking either perforin or granzyme mediated cytolytic mechanisms
28. Perforin, a cytotoxic molecule which mediates cell necrosis, is not required for the early control of mycobacterial infection in mice
29. CD8+ CTL from lungs of Mycobacterium tuberculosis infected mice express perforin in vivo and lyse infected macrophages
30. The central effectors of cell death in the immune system
31. Identification and characterization of a dimerisation domain in CED-6. An adapter protein involved in engulfment of apoptotic cells
32. Macrophage apoptosis in mycobacterial infection
33. Apoptosis, but not necrosis, of infected monocytes is coupled with killing of intracellular Bacillus Calmette-Guerin
34. Vaccines, genes and trials
35. CD95 signaling is not required for the down regulation of cellular responses to systemic Mycobacterium tuberculosis infection