Systemic administration of acidic fibroblast growth factor ameliorates the ischemic injury of the retina in rats

Neuroscience Letters

Volumn 255, Issue 1, 1998, Pages 1-4

  Cuevas, Pedro ^a   Carceller, Fernando ^a   Redondo Horcajo, Mariano ^b   Maria Lozano, Rosa ^b   Giménez Gallego, Guillermo ^b  

^a HOSPITAL RAMÓN Y CAJAL   (Spain)

^b CSIC   (Spain)

Author keywords

Fibroblast growth factor; Neuroprotection; Rat; Retinal ischemia

Indexed keywords

ACIDIC FIBROBLAST GROWTH FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG SAFETY; INTRACAMERAL DRUG ADMINISTRATION; INTRAPERITONEAL DRUG ADMINISTRATION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RAT; REPERFUSION INJURY; RETINA BIPOLAR GANGLION CELL; RETINA BLOOD FLOW; RETINA GANGLION CELL; RETINA INJURY; RETINA ISCHEMIA;

ANIMALS; FEMALE; FIBROBLAST GROWTH FACTOR 1; HUMANS; INJECTIONS, INTRA-ARTERIAL; ISCHEMIA; MALE; NEUROPROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; RETINAL VESSELS;

EID: 0032500713     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(98)00672-7     Document Type: Article

References (24)

1. Bresnick G.H. Excitotoxins: a possible new mechanism for the pathogenesis of ischemic retinal damage. Arch. Ophthalmol. 107:1989;339-341.
2. Cheng B., Mattson M.P. NGF and bFGF protect rat hippocampal and human cortical neurons against hypoglucemic damage by stabilising calcium homeostasis. Neuron. 7:1991;1031-1041.
3. Cuevas P., Fernandez Ayerdi A., Carceller F., Collin S., Mascarelli F., Muñoz Willery Y., Giménez-Gallego G. Central nervous system distribution of fibroblast growth factor injected into the blood stream. Neurol. Res. 18:1996;267-272.
4. Cuevas P., Carceller F., Giménez-Gallego G. Intravenous fibroblast growth factor penetrates the blood-brain barrier and protects hippocampal neurons against ischemia-reperfusion injury. Surg. Neurol. 49:1998;77-84.
5. Cuevas P., Carceller F., Reimers D., Saenz de Tejada Y., Giménez-Gallego G. Acidic fibroblast growth factor rescues gerbil hippocampal neurons from ischemic apoptotic death. Neurol. Res. 20:1998;271-274.
6. Freese A., Finklestein S.P., DiFiglia M. Basic fibroblast growth factor protects striatal neurons in vitro from NMDA-receptor mediated excitotoxicity. Brain Res. 575:1992;351-355.
7. Heidinger V., Hicks D., Sahel J., Dreyfus H. Peptide growth factors but not ganglioside protect against excitotoxicity in rat retinal neurons in vitro. Brain Res. 767:1997;279-288.
8. Hughes W.F. Quantitation of ischemic damage in the rat retina. Exp. Eye Res. 53:1991;573-582.
9. Ikeda K., Iwasaki Y., Tagaya N., Shiojima T., Kobayashi T., Kinoshita M. Neuroprotective effect of basic fibroblast growth factor on wobbler mouse motor neuron disease. Neurol. Res. 17:1995;445-448.
10. Ishihara A., Saito H., Nishiyama N. Basic fibroblast growth factor ameliorates learning deficits in basal forebrain-lesioned mice. Jpn. J. Pharmacol. 59:1992;7-13.
11. Kirschner P.B., Henshaw R., Weise J., Trubetskoy V., Finklestein S., Schultz J.B., Beal M.F. Basic fibroblast growth factor protects against excitotoxicity and chemical hypoxia in both neonatal and adult rats. J. Cereb. Blood Flow Metab. 15:1995;619-623.
12. Lavail N.M., Unoki K., Yasumura D., Matthes M.T., Yancopoulos G.D., Steinberg R.H. Multiple growth factors, cytokines and neurotrophins rescue photoreceptors from the damaging effects of constant light. Proc. Natl. Acad. Sci. USA. 89:1992;11249-11253.
13. Lefaucher J.P., Gjata B., Lafont H., Sebile A. Angiogenic and inflammatory responses following skeletal muscle injury are altered by immune neutralization of endogenous basic fibroblast growth factor insulin-like growth factor-1 and transforming growth factor-β1. J. Neuroimmunol. 70:1996;37-44.
14. Matson M.P., Kumar K., Cheng B., Wang H., Michelis E.K. Basic FGF regulates the expression of a functional 71 Kda NMDA receptor protein that mediates calcium influx and neurotoxicity in cultured hippocampal neurons. J. Neurosci. 13:1993;4575-4588.
15. Mattson M.P., Cheng B., Smith-Swintosky V.L. Growth factor-mediated protection from excitotoxicity and disturbances in calcium and free radical metabolism. Semin. Neurosci. 5:1993;295-307.
16. Miyashiro M., Ogata N., Takahashi Kl., Matsushima M., Yamamoto C., Yamada H., Uyama M. Expression of basic fibroblast growth factor and its receptor mRNA in retinal tissue following ischemic injury in the rat. Graefe's Arch. Clin. Exp. Ophthalmol. 236:1998;295-300.
17. Otto D., Unsicker K. Basic FGF reverses chemical and morphological deficits in the nigrostriatal system of MPTP-treated mice. J. Neurosci. 10:1990;1912-1921.
18. Stefansson E., Wilson C.A., Schoen T., Kuwabara T. Experimental ischemia induces cell mitosis in the adult rat retina. Invest. Ophthalmol. Vis. Sci. 29:1988;1050-1055.
19. Takami K., Iwane M., Kiyota Y., Miyamoto M., Tsukuda R., Shiosaka S. Increase of basic fibroblast growth factor immunoreactivity and its mRNA level in rat brain following transient forebrain ischemia. Exp. Brain Res. 90:1992;1-10.
20. Unoki K., Lavail M.M. Protection of the rat retina from ischemic injury by brain-derived neurotrophic factor, ciliary neurotrophic factor, and basic fibroblast growth factor. Invest. Ophthalmol. Vis. Sci. 35:1994;907-915.
21. Walicke P.A., Cowan W.M., Ueno N., Baird A., Guillemin R. Fibroblast growth factor promotes survival of dissociated hippocampal neurons and enhances neurite extension. Proc. Natl. Acad. Sci. USA. 83:1986;3012-3016.
22. Zazo M., Lozano R.M., Ortega S., Varela J., Diaz-Orejas R., Ramirez J.M., Giménez-Gallego G. High-level synthesis in Escherichia coli of shortened and full-length human acidic fibroblast growth factor and purification in a form stable in aqueous solutions. Gene. 113:1992;231-238.
23. Zhang C., Takahashi K., Lam T.T., Tso M.O.M. Effects of basic fibroblast growth factor in retinal ischemia. Invest. Ophathlmol. Vis. Sci. 35:1994;3163-3168.
24. Zimmermann M. Ethical principles for the maintenance and use of animals in neuroscience research. Neurosci. Lett. 73:1987;1.