-
1
-
-
58749098455
-
-
Humana Press, Clifton, NJ
-
Ougolkov A.V., Billadeau D.D. Inhibition of Glycogen Synthase Kinase-3. Wnt Signaling 2009, Humana Press, Clifton, NJ, p. 67-75.
-
(2009)
Inhibition of Glycogen Synthase Kinase-3. Wnt Signaling
, pp. 67-75
-
-
Ougolkov, A.V.1
Billadeau, D.D.2
-
2
-
-
47349090556
-
The role of glycogen synthase kinase-3b in normal haematopoiesis, angiogenesis and leukaemia
-
Holmes T., O'Brien T.A., Knight R., Lindeman R., Symonds G., Dolnikov A. The role of glycogen synthase kinase-3b in normal haematopoiesis, angiogenesis and leukaemia. Curr Med Chem 2008, 15:1493-1499.
-
(2008)
Curr Med Chem
, vol.15
, pp. 1493-1499
-
-
Holmes, T.1
O'Brien, T.A.2
Knight, R.3
Lindeman, R.4
Symonds, G.5
Dolnikov, A.6
-
3
-
-
0035477020
-
GSK3 takes centre stage more than 20 years after its discovery
-
Frame S., Cohen P. GSK3 takes centre stage more than 20 years after its discovery. Biochem J 2001, 359:1-16.
-
(2001)
Biochem J
, vol.359
, pp. 1-16
-
-
Frame, S.1
Cohen, P.2
-
4
-
-
67650569513
-
Glycogen synthase kinase 3: more than a namesake
-
Rayasam G.V., Tulasi V.K., Sodhi R., Davis J.A., Ray A. Glycogen synthase kinase 3: more than a namesake. Br J Pharmacol 2009, 156:885-898.
-
(2009)
Br J Pharmacol
, vol.156
, pp. 885-898
-
-
Rayasam, G.V.1
Tulasi, V.K.2
Sodhi, R.3
Davis, J.A.4
Ray, A.5
-
5
-
-
55249120170
-
Glycogen synthase kinase 3 in MLL leukaemia maintenance and targeted therapy
-
Wang Z., Smith K.S., Murphy M., Piloto O., Somervaille T.C.P., Cleary M.L. Glycogen synthase kinase 3 in MLL leukaemia maintenance and targeted therapy. Nature 2008, 455:1205-1209.
-
(2008)
Nature
, vol.455
, pp. 1205-1209
-
-
Wang, Z.1
Smith, K.S.2
Murphy, M.3
Piloto, O.4
Somervaille, T.C.P.5
Cleary, M.L.6
-
6
-
-
0036789185
-
Effects of a novel glycogen synthase kinase-3 inhibitor on insulin-stimulated glucose metabolism in Zucker diabetic fatty (fa/fa) rats
-
Cline G.W., Johnson K., Regittnig W., et al. Effects of a novel glycogen synthase kinase-3 inhibitor on insulin-stimulated glucose metabolism in Zucker diabetic fatty (fa/fa) rats. Diabetes 2002, 51:2903-2910.
-
(2002)
Diabetes
, vol.51
, pp. 2903-2910
-
-
Cline, G.W.1
Johnson, K.2
Regittnig, W.3
-
7
-
-
0037339766
-
Selective glycogen synthase kinase 3 inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo
-
Ring D.B., Johnson K.W., Henriksen E.J., et al. Selective glycogen synthase kinase 3 inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo. Diabetes 2003, 52:588-595.
-
(2003)
Diabetes
, vol.52
, pp. 588-595
-
-
Ring, D.B.1
Johnson, K.W.2
Henriksen, E.J.3
-
8
-
-
34547114509
-
Inhibition of glycogen synthase kinase-3 activity leads to epigenetic silencing of nuclear factor kB target genes and induction of apoptosis in chronic lymphocytic leukemia B cells
-
Ougolkov A.V., Bone N.D., Fernandez-Zapico M.E., Kay N.E., Billadeau D.D. Inhibition of glycogen synthase kinase-3 activity leads to epigenetic silencing of nuclear factor kB target genes and induction of apoptosis in chronic lymphocytic leukemia B cells. Blood 2007, 110:735-742.
-
(2007)
Blood
, vol.110
, pp. 735-742
-
-
Ougolkov, A.V.1
Bone, N.D.2
Fernandez-Zapico, M.E.3
Kay, N.E.4
Billadeau, D.D.5
-
9
-
-
62649139996
-
Glycogen synthase kinase 3b missplicing contributes to leukemia stem cell generation
-
Abrahamsson A.E., Geron I., Gotlib J., et al. Glycogen synthase kinase 3b missplicing contributes to leukemia stem cell generation. Proc Nat Acad Sci U S A 2009, 106:3925-3929.
-
(2009)
Proc Nat Acad Sci U S A
, vol.106
, pp. 3925-3929
-
-
Abrahamsson, A.E.1
Geron, I.2
Gotlib, J.3
-
10
-
-
62449130185
-
Knockin of mutant PIK3CA activates multiple oncogenic pathways
-
Gustin J.P., Karakas B., Weiss M.B., et al. Knockin of mutant PIK3CA activates multiple oncogenic pathways. Proc Nat Acad Sci U S A 2009, 106:2835-2840.
-
(2009)
Proc Nat Acad Sci U S A
, vol.106
, pp. 2835-2840
-
-
Gustin, J.P.1
Karakas, B.2
Weiss, M.B.3
-
11
-
-
61349146623
-
Potential therapeutic effect of glycogen synthase kinase 3b inhibition against human glioblastoma
-
Miyashita K., Kawakami K., Nakada M., et al. Potential therapeutic effect of glycogen synthase kinase 3b inhibition against human glioblastoma. Clin Cancer Res 2009, 15:887-897.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 887-897
-
-
Miyashita, K.1
Kawakami, K.2
Nakada, M.3
-
12
-
-
35348948074
-
Analysis of cell differentiation by division tracking cytometry
-
Ko K.-H., Odell R., Nordon R.E. Analysis of cell differentiation by division tracking cytometry. Cytometry Part A 2007, 71A:773-782.
-
(2007)
Cytometry Part A
, vol.71 A
, pp. 773-782
-
-
Ko, K.-H.1
Odell, R.2
Nordon, R.E.3
-
13
-
-
0038005018
-
DAVID: Database for Annotation, Visualization, and Integrated Discovery
-
Dennis G., Sherman B., Hosack D., et al. DAVID: Database for Annotation, Visualization, and Integrated Discovery. Genome Biology 2003, 4:R60.
-
(2003)
Genome Biology
, vol.4
-
-
Dennis, G.1
Sherman, B.2
Hosack, D.3
-
14
-
-
61449172037
-
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
-
Huang D.W., Sherman B.T., Lempicki R.A. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 2008, 4:44-57.
-
(2008)
Nat Protoc
, vol.4
, pp. 44-57
-
-
Huang, D.W.1
Sherman, B.T.2
Lempicki, R.A.3
-
15
-
-
47949127436
-
Glycogen synthase kinase-3b inhibition preserves hematopoietic stem cell activity and inhibits leukemic cell growth
-
Holmes T., O'Brien T.A., Knight R., et al. Glycogen synthase kinase-3b inhibition preserves hematopoietic stem cell activity and inhibits leukemic cell growth. Stem Cells 2008, 26:1288-1297.
-
(2008)
Stem Cells
, vol.26
, pp. 1288-1297
-
-
Holmes, T.1
O'Brien, T.A.2
Knight, R.3
-
16
-
-
0030863757
-
Immune-deficient SCID and NOD/SCID mice models as functional assays for studying normal and malignant human hematopoiesis
-
Lapidot T., Fajerman Y., Kollet O. Immune-deficient SCID and NOD/SCID mice models as functional assays for studying normal and malignant human hematopoiesis. J Mol Med 1997, 75:664-673.
-
(1997)
J Mol Med
, vol.75
, pp. 664-673
-
-
Lapidot, T.1
Fajerman, Y.2
Kollet, O.3
-
17
-
-
0032532632
-
Activated endothelial cells induce apoptosis in leukemic cells by endothelial interleukin-8
-
Terui Y., Ikeda M., Tomizuka H., et al. Activated endothelial cells induce apoptosis in leukemic cells by endothelial interleukin-8. Blood 1998, 92:2672-2680.
-
(1998)
Blood
, vol.92
, pp. 2672-2680
-
-
Terui, Y.1
Ikeda, M.2
Tomizuka, H.3
-
18
-
-
0035692411
-
Mechanisms associated with cell adhesion mediated drug resistance (CAM-DR) in hematopoietic malignancies
-
Hazlehurst L.A., Dalton W.S. Mechanisms associated with cell adhesion mediated drug resistance (CAM-DR) in hematopoietic malignancies. Cancer Metast Rev 2001, 20:43-50.
-
(2001)
Cancer Metast Rev
, vol.20
, pp. 43-50
-
-
Hazlehurst, L.A.1
Dalton, W.S.2
-
19
-
-
33744476502
-
A crosstalk between the Wnt and the adhesion-dependent signaling pathways governs the chemosensitivity of acute myeloid leukemia
-
De Toni F., Racaud-Sultan C., Chicanne G., et al. A crosstalk between the Wnt and the adhesion-dependent signaling pathways governs the chemosensitivity of acute myeloid leukemia. Oncogene 2006, 25:3113-3122.
-
(2006)
Oncogene
, vol.25
, pp. 3113-3122
-
-
De Toni, F.1
Racaud-Sultan, C.2
Chicanne, G.3
-
20
-
-
0141461414
-
Interaction between leukemic-cell VLA-4 and stromal fibronectin is a decisive factor for minimal residual disease of acute myelogenous leukemia
-
Matsunaga T., Takemoto N., Sato T., et al. Interaction between leukemic-cell VLA-4 and stromal fibronectin is a decisive factor for minimal residual disease of acute myelogenous leukemia. Nat Med 2003, 9:1158-1165.
-
(2003)
Nat Med
, vol.9
, pp. 1158-1165
-
-
Matsunaga, T.1
Takemoto, N.2
Sato, T.3
-
21
-
-
0034652115
-
Survival function of ERK1/2 as IL-3-activated, staurosporine-resistant Bcl2 kinases
-
Deng X., Ruvolo P., Carr B., May W.S. Survival function of ERK1/2 as IL-3-activated, staurosporine-resistant Bcl2 kinases. Proc Nat Acad Sci U S A 2000, 97:1578-1583.
-
(2000)
Proc Nat Acad Sci U S A
, vol.97
, pp. 1578-1583
-
-
Deng, X.1
Ruvolo, P.2
Carr, B.3
May, W.S.4
-
22
-
-
26444608505
-
Therapeutic-antagonists of oestrogens can be produced for cancer and other therapies using cytochromes P450 (CYP)
-
Wiseman A. Therapeutic-antagonists of oestrogens can be produced for cancer and other therapies using cytochromes P450 (CYP). Med Hypotheses 2005, 65:1088-1090.
-
(2005)
Med Hypotheses
, vol.65
, pp. 1088-1090
-
-
Wiseman, A.1
-
23
-
-
64049107948
-
Sequential cancer immunotherapy: targeted activity of dimeric TNF and IL-8
-
Bauer S., Adrian N., Siebenborn U., et al. Sequential cancer immunotherapy: targeted activity of dimeric TNF and IL-8. Cancer Immun 2009, 9:2.
-
(2009)
Cancer Immun
, vol.9
, pp. 2
-
-
Bauer, S.1
Adrian, N.2
Siebenborn, U.3
-
25
-
-
36749102595
-
Elevated level of SUMOylated IRF-1 in tumor cells interferes with IRF-1-mediated apoptosis
-
Park J., Kim K., Lee E.-J., et al. Elevated level of SUMOylated IRF-1 in tumor cells interferes with IRF-1-mediated apoptosis. Proc Nat Acad Sci U S A 2007, 104:17028-17033.
-
(2007)
Proc Nat Acad Sci U S A
, vol.104
, pp. 17028-17033
-
-
Park, J.1
Kim, K.2
Lee, E.-J.3
-
26
-
-
33845532359
-
The paradox of pro-inflammatory cytokines in cancer
-
Dinarello C.A. The paradox of pro-inflammatory cytokines in cancer. Cancer Metast Rev 2006, 25:307-313.
-
(2006)
Cancer Metast Rev
, vol.25
, pp. 307-313
-
-
Dinarello, C.A.1
-
27
-
-
4444353257
-
Tumor progression: the effects of thrombospondin-1 and -2
-
Lawler J., Detmar M. Tumor progression: the effects of thrombospondin-1 and -2. Int J Biochem Cell Biol 2004, 36:1038-1045.
-
(2004)
Int J Biochem Cell Biol
, vol.36
, pp. 1038-1045
-
-
Lawler, J.1
Detmar, M.2
-
28
-
-
53049087888
-
Bone morphogenetic protein-Smad pathway as drug targets for osteoporosis and cancer therapy
-
Li B. Bone morphogenetic protein-Smad pathway as drug targets for osteoporosis and cancer therapy. Endocr Metab Immune Disord Drug Targets 2008, 8:208-219.
-
(2008)
Endocr Metab Immune Disord Drug Targets
, vol.8
, pp. 208-219
-
-
Li, B.1
-
29
-
-
0032530215
-
Molecular epidemiology of human cancer: contribution of mutation spectra studies of tumor suppressor genes
-
Hussain S.P., Harris C.C. Molecular epidemiology of human cancer: contribution of mutation spectra studies of tumor suppressor genes. Cancer Res 1998, 58:4023-4037.
-
(1998)
Cancer Res
, vol.58
, pp. 4023-4037
-
-
Hussain, S.P.1
Harris, C.C.2
-
30
-
-
5144223361
-
Gonadotropin-induced gene regulation in human granulosa cells obtained from IVF patients: modulation of genes coding for growth factors and their receptors and genes involved in cancer and other diseases
-
Rimon E., Sasson R., Dantes A., Land-Bracha A., Amsterdam A. Gonadotropin-induced gene regulation in human granulosa cells obtained from IVF patients: modulation of genes coding for growth factors and their receptors and genes involved in cancer and other diseases. Int J Oncol 2004, 24:1325-1338.
-
(2004)
Int J Oncol
, vol.24
, pp. 1325-1338
-
-
Rimon, E.1
Sasson, R.2
Dantes, A.3
Land-Bracha, A.4
Amsterdam, A.5
-
31
-
-
54249107246
-
The promise of cancer therapeutics targeting the TNF-related apoptosis-inducing ligand and TRAIL receptor pathway
-
Wang S. The promise of cancer therapeutics targeting the TNF-related apoptosis-inducing ligand and TRAIL receptor pathway. Oncogene 2008, 27:6207-6215.
-
(2008)
Oncogene
, vol.27
, pp. 6207-6215
-
-
Wang, S.1
-
32
-
-
0029022737
-
Human interleukin-3 receptor modulates bcl-2 mRNA and protein levels through protein kinase C in TF-1 cells
-
Rinaudo M.S., Su K., Falk L.A., Halder S., Mufson R.A. Human interleukin-3 receptor modulates bcl-2 mRNA and protein levels through protein kinase C in TF-1 cells. Blood 1995, 86:80-88.
-
(1995)
Blood
, vol.86
, pp. 80-88
-
-
Rinaudo, M.S.1
Su, K.2
Falk, L.A.3
Halder, S.4
Mufson, R.A.5
-
33
-
-
34247329753
-
Nilotinib exerts equipotent antiproliferative effects to imatinib and does not induce apoptosis in CD34+ CML cells
-
Jorgensen H.G., Allan E.K., Jordanides N.E., Mountford J.C., Holyoake T.L. Nilotinib exerts equipotent antiproliferative effects to imatinib and does not induce apoptosis in CD34+ CML cells. Blood 2007, 109:4016-4019.
-
(2007)
Blood
, vol.109
, pp. 4016-4019
-
-
Jorgensen, H.G.1
Allan, E.K.2
Jordanides, N.E.3
Mountford, J.C.4
Holyoake, T.L.5
-
34
-
-
0037059012
-
Preferential induction of apoptosis for primary human leukemic stem cells
-
Guzman M.L., Swiderski C.F., Howard D.S., et al. Preferential induction of apoptosis for primary human leukemic stem cells. Proc Nat Acad Sci U S A 2002, 99:16220-16225.
-
(2002)
Proc Nat Acad Sci U S A
, vol.99
, pp. 16220-16225
-
-
Guzman, M.L.1
Swiderski, C.F.2
Howard, D.S.3
-
35
-
-
65449172847
-
Drug development targeting the glycogen synthase kinase-3b (GSK-3b)-mediated signal transduction pathway: targeting the Wnt pathway and transplantation therapy as strategies for retinal repair
-
Osakada F., Takahashi M. Drug development targeting the glycogen synthase kinase-3b (GSK-3b)-mediated signal transduction pathway: targeting the Wnt pathway and transplantation therapy as strategies for retinal repair. J Pharmacol Sci 2009, 109:168-173.
-
(2009)
J Pharmacol Sci
, vol.109
, pp. 168-173
-
-
Osakada, F.1
Takahashi, M.2
-
36
-
-
69249222794
-
New perspectives on APC control of cell fate and proliferation in colorectal cancer
-
Phelps R.A., Broadbent T.J., Stafforini D.M., Jones D.A. New perspectives on APC control of cell fate and proliferation in colorectal cancer. Cell Cycle 2009, 15:2549-2556.
-
(2009)
Cell Cycle
, vol.15
, pp. 2549-2556
-
-
Phelps, R.A.1
Broadbent, T.J.2
Stafforini, D.M.3
Jones, D.A.4
-
37
-
-
1242267927
-
Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor
-
Sato N., Meijer L., Skaltsounis L., Greengard P., Brivanlou A.H. Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor. Nat Med 2004, 10:55-63.
-
(2004)
Nat Med
, vol.10
, pp. 55-63
-
-
Sato, N.1
Meijer, L.2
Skaltsounis, L.3
Greengard, P.4
Brivanlou, A.H.5
-
38
-
-
0033026520
-
TCF-1-mediated transcription in T lymphocytes: differential role for glycogen synthase kinase-3 in fibroblasts and T cells
-
Staal F.J.T., Burgering B.M.T., van de Wetering M., Clevers H.C. TCF-1-mediated transcription in T lymphocytes: differential role for glycogen synthase kinase-3 in fibroblasts and T cells. Int Immunol 1999, 11:317-323.
-
(1999)
Int Immunol
, vol.11
, pp. 317-323
-
-
Staal, F.J.T.1
Burgering, B.M.T.2
van de Wetering, M.3
Clevers, H.C.4
-
39
-
-
67649200331
-
Monoclonal antibody-mediated targeting of CD123, IL-3 receptor a chain, eliminates human acute myeloid leukemic stem cells
-
Jin L., Lee E.M., Ramshaw H.S., et al. Monoclonal antibody-mediated targeting of CD123, IL-3 receptor a chain, eliminates human acute myeloid leukemic stem cells. Cell Stem Cell 2009, 5:31-42.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 31-42
-
-
Jin, L.1
Lee, E.M.2
Ramshaw, H.S.3
-
40
-
-
77953975330
-
-
Life in Progress Editions, Roscoff, France
-
Meijer L., Guyard N., Skaltsounis L., Eisenbrand G. Indirubin, the Red Shade of Indigo 2006, Life in Progress Editions, Roscoff, France.
-
(2006)
Indirubin, the Red Shade of Indigo
-
-
Meijer, L.1
Guyard, N.2
Skaltsounis, L.3
Eisenbrand, G.4
|