Drug development targeting the glycogen synthase kinase-3/ß(GSK-3/ ß)-mediated signal transduction pathway: Targeting the Wnt pathway and transplantation therapy as strategies for retinal repair

Journal of Pharmacological Sciences

Volumn 109, Issue 2, 2009, Pages 168-173

  Osakada, Fumitaka ^a   Takahashi, Masayo ^a  

^a RIKEN   (Japan)

Author keywords

Cell replacement; Eye; Glycogen synthase kinase 3 (GSK 3 ); Induced pluripotent stem (iPS) cell; Neurogenesis; Rod and cone photoreceptor

Indexed keywords

BETA CATENIN; FRIZZLED PROTEIN; GLYCOGEN SYNTHASE KINASE 3 INHIBITOR; GLYCOGEN SYNTHASE KINASE 3BETA; WNT PROTEIN; GLYCOGEN SYNTHASE KINASE 3;

CELL ACTIVATION; CELL DIFFERENTIATION; CELL PROLIFERATION; DRUG EFFECT; DRUG TARGETING; EMBRYONIC STEM CELL; HUMAN; MUELLER CELL; NERVE CELL NETWORK; NERVE REGENERATION; NEURAL STEM CELL; NONHUMAN; PHOTORECEPTOR; PIGMENT EPITHELIUM; PLURIPOTENT STEM CELL; PROTEIN FUNCTION; RETINA INJURY; RETINA NERVE CELL; SHORT SURVEY; SIGNAL TRANSDUCTION; STEM CELL TRANSPLANTATION; VISION; ANIMAL; DRUG DELIVERY SYSTEM; METABOLISM; METHODOLOGY; PHOTORECEPTOR CELL; PHYSIOLOGY; RAT; RETINA; REVIEW; TRANSPLANTATION;

ANIMALS; DRUG DELIVERY SYSTEMS; EMBRYONIC STEM CELLS; GLYCOGEN SYNTHASE KINASE 3; NERVE REGENERATION; PHOTORECEPTOR CELLS, VERTEBRATE; RATS; RETINA; SIGNAL TRANSDUCTION; STEM CELL TRANSPLANTATION; WNT PROTEINS;

EID: 65449172847     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.08R19FM     Document Type: Short Survey

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