Peroxisome proliferator-activated receptors (PPARs)-independent functions of fish oil on glucose and lipid metabolism in diet-induced obese mice

Lipids in Health and Disease

Volumn 9, Issue , 2010, Pages

  Wakutsu, Masaki ^a   Tsunoda, Nobuyo ^a   Shiba, Sachiko ^a   Muraki, Etsuko ^a   Kasono, Keizo ^a  

^a JOSAI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

FISH OIL; GLUCOSE; LIPID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA ANTAGONIST; TRIACYLGLYCEROL; ACYL COENZYME A OXIDASE; FATTY ACID SYNTHASE; MESSENGER RNA; OMEGA 3 FATTY ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; SREBF1 PROTEIN, MOUSE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIETARY INTAKE; DRUG MECHANISM; FEMALE; GLUCOSE METABOLISM; GLUCOSE TOLERANCE; LIPID BLOOD LEVEL; LIPID LIVER LEVEL; LIPID METABOLISM; MOUSE; NONHUMAN; OBESITY; TRIACYLGLYCEROL BLOOD LEVEL; ANIMAL; BLOOD; CELL SIZE; DIET THERAPY; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; GLUCOSE INTOLERANCE; HYPERTRIGLYCERIDEMIA; INSULIN RESISTANCE; INTRAABDOMINAL FAT; LIVER; METABOLISM; MOUSE STRAIN; PATHOLOGY;

MUS;

ACYL-COA OXIDASE; ANIMALS; CELL SIZE; FATTY ACID SYNTHETASE COMPLEX; FATTY ACIDS, OMEGA-3; FEMALE; FISH OILS; GENE EXPRESSION REGULATION; GLUCOSE; GLUCOSE INTOLERANCE; HYPERTRIGLYCERIDEMIA; INSULIN RESISTANCE; INTRA-ABDOMINAL FAT; LIPID METABOLISM; LIPIDS; LIVER; MICE; MICE, INBRED STRAINS; OBESITY; PPAR ALPHA; PPAR GAMMA; RNA, MESSENGER; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

EID: 77956569751     PISSN: None     EISSN: 1476511X     Source Type: Journal    
DOI: 10.1186/1476-511X-9-101     Document Type: Article

References (37)

1. Fish oil prevents insulin resistance induced by high-fat feeding in rats. LH Storlien EW Kraegen DJ Chisholm GL Ford DG Bruce WS Pascoe, Science 1987 37 885 8 10.1126/science.3303333
2. Docosahexaenoic acid supplementation decreases remnant-like particle-cholesterol and increases the n-3 index in hypertriglyceridemic men. DS Kelly D Siegel M Vemuri GH Chung BE Mackey, J Nutr 2008 138 30 5 18156400
3. Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma. SA Kliewer SS Sundseth SA Jones PJ Brown GB Wisely C Koble P Devchand W Wahli TM Willson JM Lenhard JM Lehmann, Proc Natl Acad Sci USA 1997 94 4318 23 10.1073/pnas.94.9.4318 9113987
4. An overview on biological mechanisms of PPARs. BP Kota TH Huang BD Roufogalis, Pharmacol Res 2005 51 85 94 10.1016/j.phrs.2004.07.012 15629253
5. Troglitazone Increases the number of small adipocytes without the change of white adipose tissue mass in obese zucker rats. A Okuno H Tamemoto K Tobe K Ueki Y Mori K Iwamoto K Umesono Y Akanuma T Fujiwara H Horikoshi Y Yazaki T Kadowaki, J Clin Invest 1998 101 1354 61 10.1172/JCI1235 9502777
6. PPAR delta as a therapeutic target in metabolic disease. SM Reilly CH Lee, FEBS Lett 2008 582 26 31 10.1016/j.febslet.2007.11.040 18036566
7. Pole of the peroxisome proliferator-activated receptor (PPAR) in mediating the effects of fibrates and fatty acids on gene expression. K Schoonjans B Staels J Auwerx, J Lipid Res 1996 37 907 25 8725145
8. Mechanism of actin of fibrates on lipid and lipoprotein metabolism. B Staels J Dallongeville J Auwerx K Schoonjans E Leitersdorf JC Fruchart, Circulation 1998 98 2088 93 9808609
9. An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor (PPAR). JM Lehmann LB Moore TA Smith-Oliver WO Wilkison TM Willson SA Kliewer, J Biol Chem 1995 270 12953 6 10.1074/jbc.270.50.30221 7768881
10. The metabolic syndrome: peroxisome proliferator-activated receptor and its therapeutic modulation. M Gurnell DB Savage V Chatterjee K Krishna S O' Rahilly, J Clin Endocrinol Metab 2003 88 2412 21 10.1210/jc.2003-030435 12788836
11. Comparison of effect of pioglitazone with metformin or sulfonylurea (monotherapy and combination therapy) on postload glycemia and composite insulin sensitivity index during an oral glucose tolerance test in patients with type 2 diabetes. A Ceriello D Johns M Widel D Eckland KJ Gilmore MH Tan, Diabetes Care 2005 28 266 72 10.2337/diacare.28.2.266 15677777
12. Fish oil feeding decreases mature sterol regulatory element binding protein 1 (SREBP-1) by down-regulation of SREBP-1c mRNA in mouse liver. A possible mechanism for down-regulation of lipogenic enzyme mRNAs. HJ Kim M Takahashi O Ezaki, J Biol Chem 1999 274 25892 8 10.1074/jbc.274.36.25892 10464332
13. SREBPs: physiology and pathophysiology of the SREBP family. H Shimano, FEBS J 2009 276 616 21 10.1111/j.1742-4658.2008.06806.x 19143830
14. Peroxisome proliferator-activated receptor is not rate-limiting for the lipoprotein-lowering action of fish oil. J Dallongeville E Baugé A Tailleux JM Peters FJ Gonzalez JC Fruchart B Staels, J Biol Chem 2001 276 4634 9 10.1074/jbc.M008809200 11050100
15. Interaction of fenofibrate and fish oil in relation to lipid metabolism in mice. T Arai H Kim H Chiba A Matsumoto, J Atheroscler Tromb 2009 16 283 91
16. Fish oil regulates adiponectin secretion by a peroxisome proliferator-activated receptor - dependent mechanism in mice. S Neschen K Morino JC Rossbacher RL Pongratz GW Cline S Sono M Gillum GI Shulman, Diabetes 2006 55 924 8 10.2337/diabetes.55.04.06.db05-0985 16567512
17. N-3 fatty acids preserve insulin sensitivity in vivo in a peroxisome proliferator-activated receptor - dependent manner. S Neschen K Morino J Dong Y Wang-Fischer GW Cline AJ Romanelli JC Rossbacher IK Moore W Regittnig DS Munoz JH Kim GI Shulman, Diabetes 2007 56 1034 41 10.2337/db06-1206 17251275
18. AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition Ad Hoc Writing Committee on the reformulation of the AIN-76A rodent diet. PG Reeves FH Nielsen GC Fahey Jr, J Nutr 1993 123 1939 51 8229312
19. High-fat diet-induced hyperglycemia and obesity in mice: differential effects of dietary oils. S Ikemoto M Takahashi N Tsunoda K Maruyama H Itakura O Ezaki, Metabolism 1996 45 1539 46 10.1016/S0026-0495(96)90185-7 8969289
20. Inhibition of peroxisome-proliferator-activated receptor (PPAR) by MK886. JP Kehrer SS Biswal LA Eunhye P Thuillier K Datta SM Fischer HPV Heuvel, Biochem J 2001 356 899 906 10.1042/0264-6021:3560899 11389700
21. Peroxisome proliferator-activated receptor agonist-induced down-regulation of hepatic glucocorticoid receptor expression in SD rats. X Chen MLW Sun Y Bi M Cai H Liang Q Yu X He J Weng, Biochem Biophys Res Commun 2008 368 865 70 10.1016/j.bbrc.2008.01.152 18267115
22. 2. HP Raikwar G Muthian J Rajasingh CN Johnson JJ Bright, J Neuroimmunol 2006 178 76 86 10.1016/j.jneuroim.2006.05.013 16844232
23. High-monounsaturated fat diet-induced obesity and diabetes in C57BL/6J mice. N Tsunoda S Ikemoto M Takahashi K Maruyama H Watanabe N Goto O Ezaki, Metabolism 1998 47 724 30 10.1016/S0026-0495(98)90037-3 9627373
24. A rapid method of total lipid extraction and purification. EG Bligh WJ Dyer, Can J Biochem Physiol 1959 37 911 7 13671378
25. n-3 fatty acids and gene expression. RD Deckelbaum TS Worgall T Seo, Am J Clin Nutr 2006 83 suppl 1520S 5S 16841862
26. N-3 polyunsaturated fatty acid regulation of hepatic gene transcription. DB Jump, Curr Opin Lipidol 2008 19 242 7 10.1097/MOL.0b013e3282ffaf6a 18460914
27. Are fish oil omega-3 long-chain fatty acids and their derivatives peroxisome proliferator-activated receptor agonists? OA Gani, Cardiovascular Diabetology 2008 7 1 6 10.1186/1475-2840-7-6 18171473
28. Cross-talk between peroxisome proliferator-activated receptor (PPAR) and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. I. PPARs suppress sterol regulatory element binding protein-1c promoter through inhibition of LXR signaling. T Yoshikawa T Ide H Shimano N Yahagi KM Amemiya T Matsuzaka S Yatoh T Kitamine H Okazaki Y Tamura M Sekiya A Takahashi AH Hasty R Sato H Sone J Osuga S Ishibashi N Yamada, Mol Endocriol 2003 17 1240 5 10.1210/me.2002-0190 (Pubitemid 36819948)
29. Cross-talk between peroxisome proliferator-activated receptor (PPAR) and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. II. LXRs suppress lipid degradation gene promoters through inhibition of PPAR signaling. T Ide H Shimano T Yoshikawa N Yahagi M Amemiya-K T Matsuzaka M Nakakuki S Yatoh Y Iizuka S Tomita K Ohashi A Takahashi H Sone T Gotoda J Osuga S Ishibashi N Yamada, Mol Endocriol 2003 17 1255 67 10.1210/me.2002-0191 (Pubitemid 36819949)
30. Peroxisome proliferator-activated receptor (PPAR) potentiates, whereas PPAR attenuates, glucose-stimulated insulin secretion in pancreatic -cells. K Ravnskjaer M Boergesen B Rubi JK Larsen T Nielsen J Fridriksson P Maechler S Mandrup, Endocrinology 2005 146 3266 76 10.1210/en.2004-1430 15878969
31. Peroxisome proliferator-activated receptors and insulin secretion. Y Terauchi Kadowaki, Endocrinology 2005 146 3263 5 10.1210/en.2005-0526 16009973
32. Enlarged subcutaneous abdominal adipocyte size, but not obesity itself, predicts type II diabetes independent of insulin resistance. C Weyer JE Foley C Bogardus PA Tataranni RE Pratley, Diabetologia 2000 43 1498 506 10.1007/s001250051560 11151758
33. Markers of de novo lipogenesis in adipose tissue: associations with small adipocytes andinsulin sensitivity in humans. R Roberts L Hodson AL Dennis MJ Neville SM Humphreys KE Harnden KJ Micklem KN Frayn, Diabetologia 2009 52 882 90 10.1007/s00125-009-1300-4 19252892
34. Insulin-induced GLUT4 translocation to the plasma membrane is blunted in large compared with small primary fat cells isolated from the same individual. N Franck KG Stenkula A st T Lindström P Strålfors FH Nystrom, Diabetologia 2007 50 1716 22 10.1007/s00125-007-0713-1 17572871
35. Adipose tissue, liver and pancreas structural alterations in C57BL/6 mice fed high-fat-high-sucrose diet supplemented with fish oil (n-3 fatty acid rich oil). FA Nascimento S Barbosa-da-Silva C Fernandes-Santos CA Mandarim-de-Lacerda MB Aguila, Exp Toxycol Pathol 2010 62 17 25 10.1016/j.etp.2008.12.008
36. PPAR mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance. N Kubota Y Terauchi H Miki H Tamemoto T Yamauchi K Komeda S Satoh R Nakano C Ishii T Sugiyama K Eto Y Tsubamoto A Okuno K Murakami H Sekihara G Hasegawa M Naito Y Toyoshima S Tanaka K Shiota T Kitamura T Fujita O Ezaki S Aizawa R Nagai K Tobe S Kimura T Kadowaki, Mol Cell 1999 4 597 609 10.1016/S1097-2765(00)80210-5 10549291
37. PPAR adipogenic regulator and thiazolidinedione receptor. BM Spiegeleman, Diabetes 1998 47 507 14 10.2337/diabetes.47.4.507 9568680