Dominant negative effects of a non-conducting TREK1 splice variant expressed in brain

Journal of Biological Chemistry

Volumn 285, Issue 38, 2010, Pages 29295-29304

  Veale, Emma L ^a   Rees, Kathryn A ^a   Mathie, Alistair ^a   Trapp, Stefan ^b  

^a MEDWAY SCHOOL OF PHARMACY   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; AMINO ACIDS; LAWS AND LEGISLATION; ORGANIC ACIDS; POTASSIUM;

CHANNEL ACTIVITY; DOMINANT-NEGATIVE EFFECTS; FUNCTIONAL EXPRESSION; INTRACELLULAR COMPARTMENTS; N-TERMINAL DOMAINS; NEUROPROTECTION; PAIN PERCEPTION; PCR TECHNIQUES; PLASMA MEMBRANES; SPLICE VARIANTS; TRANS-MEMBRANE DOMAINS; WHOLE CELL; WILD TYPES;

CELL MEMBRANES;

AMINO ACID; CELL MEMBRANE PROTEIN; POTASSIUM CHANNEL; PROTEIN TREK1; REGULATOR PROTEIN; UNCLASSIFIED DRUG; ISOPROTEIN; MESSENGER RNA; POTASSIUM CHANNEL PROTEIN TREK-1; TANDEM PORE DOMAIN POTASSIUM CHANNEL;

AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ARTICLE; BRAIN; CELL MEMBRANE TRANSPORT; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DIMERIZATION; FEMALE; GENETIC CODE; HUMAN; HUMAN CELL; INTRACELLULAR SPACE; MALE; MOUSE; NERVE CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN VARIANT; RAT; TRANSLATION INITIATION; WHOLE CELL; WILD TYPE; ANIMAL; C57BL MOUSE; CELL LINE; DOG; ELECTROPHYSIOLOGY; GENETICS; METABOLISM; MUTATION; SPRAGUE DAWLEY RAT;

ANIMALS; BRAIN; CELL LINE; DOGS; ELECTROPHYSIOLOGY; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL; MUTATION; POLYMERASE CHAIN REACTION; POTASSIUM CHANNELS, TANDEM PORE DOMAIN; PROTEIN ISOFORMS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER;

EID: 77956556827     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.108423     Document Type: Article

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