-
1
-
-
0032053823
-
The unique physiology of solid tumors: Opportunities (and problems) for cancer therapy
-
Brown JM, Giaccia AJ. The unique physiology of solid tumors: opportunities (and problems) for cancer therapy. Cancer Res 1998;58:1408-16.
-
(1998)
Cancer Res
, vol.58
, pp. 1408-1416
-
-
Brown, J.M.1
Giaccia, A.J.2
-
2
-
-
0032708195
-
Oxygenation of head and neck cancer: Changes during radiotherapy and impact on treatment outcome
-
Brizel DM, Dodge RK, Clough RW, Dewhirst MW. Oxygenation of head and neck cancer: changes during radiotherapy and impact on treatment outcome. Radiother Oncol 1999;53:113-7.
-
(1999)
Radiother Oncol
, vol.53
, pp. 113-117
-
-
Brizel, D.M.1
Dodge, R.K.2
Clough, R.W.3
Dewhirst, M.W.4
-
3
-
-
0034307112
-
A confirmatory prognostic study on oxygenation status and loco-regional control in advanced head and neck squamous cell carcinoma treated by radiation therapy
-
Nordsmark M, Overgaard J. A confirmatory prognostic study on oxygenation status and loco-regional control in advanced head and neck squamous cell carcinoma treated by radiation therapy. Radiother Oncol 2000;57:39-43.
-
(2000)
Radiother Oncol
, vol.57
, pp. 39-43
-
-
Nordsmark, M.1
Overgaard, J.2
-
4
-
-
0030022252
-
Tumor oxygenation predicts for the likelihood of distant metastases in human soft tissue sarcoma
-
Brizel DM, Scully SP, Harrelson JM, et al. Tumor oxygenation predicts for the likelihood of distant metastases in human soft tissue sarcoma. Cancer Res 1996;56:941-3.
-
(1996)
Cancer Res
, vol.56
, pp. 941-943
-
-
Brizel, D.M.1
Scully, S.P.2
Harrelson, J.M.3
-
5
-
-
0029775242
-
Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix
-
Hockel M, Schlenger K, Aral B, et al. Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix. Cancer Res 1996;56:4509-15.
-
(1996)
Cancer Res
, vol.56
, pp. 4509-4515
-
-
Hockel, M.1
Schlenger, K.2
Aral, B.3
-
6
-
-
0038376175
-
In vivo assessment of tumor hypoxia in lung cancer with (60)Cu-ATSM
-
Dehdashti F, Mintun, MA, Lewis JS, et al. In vivo assessment of tumor hypoxia in lung cancer with (60)Cu-ATSM. Eur J Nucl Med Mol Imaging 2003;30:844-50.
-
(2003)
Eur J Nucl Med Mol Imaging
, vol.30
, pp. 844-850
-
-
Dehdashti, F.1
Mintun, M.A.2
Lewis, J.S.3
-
7
-
-
0030249455
-
Quantifying regional hypoxia in human tumors with positron emission tomography of [18F]fluoromisonidazole: A pretherapy study of 37 patients
-
Rasey JS, Koh WJ, Evans ML, et al. Quantifying regional hypoxia in human tumors with positron emission tomography of [18F]fluoromisonidazole: a pretherapy study of 37 patients. Int J Radiat Oncol Biol Phys 1996;36:417-28.
-
(1996)
Int J Radiat Oncol Biol Phys
, vol.36
, pp. 417-428
-
-
Rasey, J.S.1
Koh, W.J.2
Evans, M.L.3
-
8
-
-
15844368087
-
Prognostic impact of hypoxia imaging with 18F-misonidazole PET in non-small cell lung cancer and head and neck cancer before radiotherapy
-
Eschmann SM, Paulsen F, Reimold M, et al. Prognostic impact of hypoxia imaging with 18F-misonidazole PET in non-small cell lung cancer and head and neck cancer before radiotherapy. J Nucl Med 2005;46:253-60.
-
(2005)
J Nucl Med
, vol.46
, pp. 253-260
-
-
Eschmann, S.M.1
Paulsen, F.2
Reimold, M.3
-
9
-
-
0037315252
-
Carbonic anhydrase IX expression, a novel surrogate marker of tumor hypoxia, is associated with a poor prognosis in non-small-cell lung cancer
-
Swinson DE, Jones JL, Richardson D, et al. Carbonic anhydrase IX expression, a novel surrogate marker of tumor hypoxia, is associated with a poor prognosis in non-small-cell lung cancer. J Clin Oncol 2003;21:473-82.
-
(2003)
J Clin Oncol
, vol.21
, pp. 473-482
-
-
Swinson, D.E.1
Jones, J.L.2
Richardson, D.3
-
10
-
-
0035503362
-
Expression of hypoxia-inducible carbonic anhydrase-9 relates to angiogenic pathways and independently to poor outcome in non-small cell lung cancer
-
Giatromanolaki A, Koukourakis MI, Sivridis E, et al. Expression of hypoxia-inducible carbonic anhydrase-9 relates to angiogenic pathways and independently to poor outcome in non-small cell lung cancer. Cancer Res 2001;61:7992-8.
-
(2001)
Cancer Res
, vol.61
, pp. 7992-7998
-
-
Giatromanolaki, A.1
Koukourakis, M.I.2
Sivridis, E.3
-
11
-
-
0035860147
-
Relation of hypoxia inducible factor 1α and 2α in operable non-small cell lung cancer to angiogenic/molecular profile of tumours and survival
-
Giatromanolaki A, Koukourakis MI, Sivridis E, et al. Relation of hypoxia inducible factor 1α and 2α in operable non-small cell lung cancer to angiogenic/molecular profile of tumours and survival. Br J Cancer 2001;85:881-90.
-
(2001)
Br J Cancer
, vol.85
, pp. 881-890
-
-
Giatromanolaki, A.1
Koukourakis, M.I.2
Sivridis, E.3
-
12
-
-
9744272532
-
Carbonic anhydrase IX in early-stage non-small cell lung cancer
-
Kim SJ, Rabbani ZN, Vollmer RT, et al. Carbonic anhydrase IX in early-stage non-small cell lung cancer. Clin Cancer Res 2004;10:7925-33.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 7925-7933
-
-
Kim, S.J.1
Rabbani, Z.N.2
Vollmer, R.T.3
-
13
-
-
23744479831
-
Expression of HIF-1α, CA IX, VEGF, and MMP-9 in surgically resected non-small cell lung cancer
-
Kim SJ, Rabbani ZN, Dewhirst MW, et al. Expression of HIF-1α, CA IX, VEGF, and MMP-9 in surgically resected non-small cell lung cancer. Lung Cancer 2005;49:325-35.
-
(2005)
Lung Cancer
, vol.49
, pp. 325-335
-
-
Kim, S.J.1
Rabbani, Z.N.2
Dewhirst, M.W.3
-
14
-
-
20944443085
-
Osteopontin expression correlates with melanoma invasion
-
Zhou Y, Dai DL, Martinka M, et al. Osteopontin expression correlates with melanoma invasion. J Invest Dermatol 2005;124:1044-52.
-
(2005)
J Invest Dermatol
, vol.124
, pp. 1044-1052
-
-
Zhou, Y.1
Dai, D.L.2
Martinka, M.3
-
15
-
-
17844388876
-
Osteopontin silencing by small interfering RNA suppresses in vitro and in vivo CT26 murine colon adenocarcinoma metastasis
-
Wai PY, Mi Z, Guo H, et al. Osteopontin silencing by small interfering RNA suppresses in vitro and in vivo CT26 murine colon adenocarcinoma metastasis. Carcinogenesis 2005;26:741-51.
-
(2005)
Carcinogenesis
, vol.26
, pp. 741-751
-
-
Wai, P.Y.1
Mi, Z.2
Guo, H.3
-
16
-
-
0033595125
-
Osteopontin induces increased invasiveness and plasminogen activator expression of human mammary epithelial cells
-
Tuck AB, Arsenault DM, O'Malley FP, et al. Osteopontin induces increased invasiveness and plasminogen activator expression of human mammary epithelial cells. Oncogene 1999;18:4237-46.
-
(1999)
Oncogene
, vol.18
, pp. 4237-4246
-
-
Tuck, A.B.1
Arsenault, D.M.2
O'Malley, F.P.3
-
17
-
-
0042709227
-
Osteopontin stimulates cell motility and nuclear factor κB-mediated secretion of urokinase type plasminogen activator through phosphatidylinositol 3-kinase/Akt signaling pathways in breast cancer cells
-
Das R, Mahabeleshwar GH, Kundu GC. Osteopontin stimulates cell motility and nuclear factor κB-mediated secretion of urokinase type plasminogen activator through phosphatidylinositol 3-kinase/Akt signaling pathways in breast cancer cells. J Biol Chem 2003;278:28593-606.
-
(2003)
J Biol Chem
, vol.278
, pp. 28593-28606
-
-
Das, R.1
Mahabeleshwar, G.H.2
Kundu, G.C.3
-
18
-
-
0030988805
-
Elevated plasma osteopontin in metastatic breast cancer associated with increased tumor burden and decreased survival
-
Singhal H, Bautista DS, Tonkin KS, et al. Elevated plasma osteopontin in metastatic breast cancer associated with increased tumor burden and decreased survival. Clin Cancer Res 1997;3:605-11.
-
(1997)
Clin Cancer Res
, vol.3
, pp. 605-611
-
-
Singhal, H.1
Bautista, D.S.2
Tonkin, K.S.3
-
19
-
-
0031662496
-
Osteopontin expression in a group of lymph node negative breast cancer patients
-
Tuck AB, O'Malley FP, Singhal H, et al. Osteopontin expression in a group of lymph node negative breast cancer patients. Int J Cancer 1998;79:502-8.
-
(1998)
Int J Cancer
, vol.79
, pp. 502-508
-
-
Tuck, A.B.1
O'Malley, F.P.2
Singhal, H.3
-
20
-
-
12244267969
-
Identification of osteopontin as a prognostic plasma marker for head and neck squamous cell carcinomas
-
Le QT Sutphin PD, Raychaudhuri S, et al. Identification of osteopontin as a prognostic plasma marker for head and neck squamous cell carcinomas. Clin Cancer Res 2003;9:59-67.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 59-67
-
-
Le, Q.T.1
Sutphin, P.D.2
Raychaudhuri, S.3
-
21
-
-
0037012338
-
Osteopontin identified as lead marker of colon cancer progression, using pooled sample expression profiling
-
Agrawal D, Chen T, Irby R, et al. Osteopontin identified as lead marker of colon cancer progression, using pooled sample expression profiling. J Natl Cancer Inst 2002;94:513-21.
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 513-521
-
-
Agrawal, D.1
Chen, T.2
Irby, R.3
-
22
-
-
0037096898
-
Prognostic significance of the metastasis-associated protein osteopontin in human breast cancer
-
Rudland PS, Platt-Higgins A, El-Tanani M, et al. Prognostic significance of the metastasis-associated protein osteopontin in human breast cancer. Cancer Res 2002;62:3417-27.
-
(2002)
Cancer Res
, vol.62
, pp. 3417-3427
-
-
Rudland, P.S.1
Platt-Higgins, A.2
El-Tanani, M.3
-
23
-
-
0035671826
-
Elevated serum bone sialoprotein and osteopontin in colon, breast, prostate, and lung cancer
-
Fedarko NS, Jain A, Karadag A, Van Eman MR, Fisher LW. Elevated serum bone sialoprotein and osteopontin in colon, breast, prostate, and lung cancer. Clin Cancer Res 2001;7:4060-6.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 4060-4066
-
-
Fedarko, N.S.1
Jain, A.2
Karadag, A.3
Van Eman, M.R.4
Fisher, L.W.5
-
24
-
-
27644526912
-
Overexpression of osteopontin is associated with more aggressive phenotypes in human non-small cell lung cancer
-
Hu Z, Lin D, Yuan J, et al. Overexpression of osteopontin is associated with more aggressive phenotypes in human non-small cell lung cancer. Clin Cancer Res 2005;11:4646-52.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 4646-4652
-
-
Hu, Z.1
Lin, D.2
Yuan, J.3
-
25
-
-
33645059086
-
Hypoxia upregulates osteopontin expression in NIH-3T3 cells via a Ras-activated enhancer
-
Zhu Y, Denhardt DT Cao H, et al. Hypoxia upregulates osteopontin expression in NIH-3T3 cells via a Ras-activated enhancer. Oncogene 2005;65:6150-8.
-
(2005)
Oncogene
, vol.65
, pp. 6150-6158
-
-
Zhu, Y.1
Denhardt, D.T.2
Cao, H.3
-
27
-
-
4544304745
-
Transient changes in oxygen tension inhibit osteogenic differentiation and Runx2 expression in osteoblasts
-
Salim A, Nacamuli RP, Morgan EF, Giaccia AJ, Longaker MT. Transient changes in oxygen tension inhibit osteogenic differentiation and Runx2 expression in osteoblasts. J Biol Chem 2004;279:40007-16.
-
(2004)
J Biol Chem
, vol.279
, pp. 40007-40016
-
-
Salim, A.1
Nacamuli, R.P.2
Morgan, E.F.3
Giaccia, A.J.4
Longaker, M.T.5
-
28
-
-
0035942271
-
Significance analysis of microarrays applied to the ionizing radiation response
-
Tusher VG, Tibshirani R, Chu G. Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci U S A 2001;98:5116-21.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 5116-5121
-
-
Tusher, V.G.1
Tibshirani, R.2
Chu, G.3
-
30
-
-
0000336139
-
Regression models and life tables
-
Cox DR. Regression models and life tables. J R Stat Soc 1972;34:187-220.
-
(1972)
J R Stat Soc
, vol.34
, pp. 187-220
-
-
Cox, D.R.1
-
31
-
-
0348143264
-
Osteopontin-dependent CD44v6 expression and cell adhesion in HepG2 cells
-
Gao C, Guo H, Downey L, Marroquin C, Wei J, Kuo PC. Osteopontin-dependent CD44v6 expression and cell adhesion in HepG2 cells. Carcinogenesis 2003;24:1871-8.
-
(2003)
Carcinogenesis
, vol.24
, pp. 1871-1878
-
-
Gao, C.1
Guo, H.2
Downey, L.3
Marroquin, C.4
Wei, J.5
Kuo, P.C.6
-
32
-
-
0036467638
-
Tumor hypoxia has independent predictor impact only in patients with node-negative cervix cancer
-
Fyles A, Milosevic M, Medley D, et al. Tumor hypoxia has independent predictor impact only in patients with node-negative cervix cancer. J Clin Oncol 2002;20:680-7.
-
(2002)
J Clin Oncol
, vol.20
, pp. 680-687
-
-
Fyles, A.1
Milosevic, M.2
Medley, D.3
-
33
-
-
0036775108
-
Hypoxic prostate/muscle pO2 ratio predicts for biochemical failure in patients with prostate cancer: Preliminary findings
-
Movsas B, Chapman JD, Hanlon AL, et al. Hypoxic prostate/muscle pO2 ratio predicts for biochemical failure in patients with prostate cancer: preliminary findings. Urology 2002;60:634-9.
-
(2002)
Urology
, vol.60
, pp. 634-639
-
-
Movsas, B.1
Chapman, J.D.2
Hanlon, A.L.3
-
34
-
-
10744219705
-
Tissue-wide expression profiling using cDNA subtraction and microarrays to identify tumor-specific genes
-
Amatschek S, Koenig U, Auer H, et al. Tissue-wide expression profiling using cDNA subtraction and microarrays to identify tumor-specific genes. Cancer Res 2004;64:844-56.
-
(2004)
Cancer Res
, vol.64
, pp. 844-856
-
-
Amatschek, S.1
Koenig, U.2
Auer, H.3
-
35
-
-
0035966343
-
The metastasis gene osteopontin: A candidate target for cancer therapy
-
Weber GF. The metastasis gene osteopontin: a candidate target for cancer therapy. Biochim Biophys Acta 2001;1552:61-85.
-
(2001)
Biochim Biophys Acta
, vol.1552
, pp. 61-85
-
-
Weber, G.F.1
-
36
-
-
6344258588
-
The role of osteopontin in tumor metastasis
-
Wai PY, Kuo PC. The role of osteopontin in tumor metastasis. J Surg Res 2004;121:228-41.
-
(2004)
J Surg Res
, vol.121
, pp. 228-241
-
-
Wai, P.Y.1
Kuo, P.C.2
-
37
-
-
4344561931
-
Osteopontin increases CD44 expression and cell adhesion in RAW 264.7 murine leukemia cells
-
Marroquin CE, Downey L, Guo H, Kuo PC. Osteopontin increases CD44 expression and cell adhesion in RAW 264.7 murine leukemia cells. Immunol Lett 2004;95:109-12.
-
(2004)
Immunol Lett
, vol.95
, pp. 109-112
-
-
Marroquin, C.E.1
Downey, L.2
Guo, H.3
Kuo, P.C.4
-
38
-
-
13244284603
-
Autocrine activation of an osteopontin-CD44-Rac pathway enhances invasion and transformation by H-RasV12
-
Teramoto H, Castellone MD, Malek RL, et al. Autocrine activation of an osteopontin-CD44-Rac pathway enhances invasion and transformation by H-RasV12. Oncogene 2005;24:489-501.
-
(2005)
Oncogene
, vol.24
, pp. 489-501
-
-
Teramoto, H.1
Castellone, M.D.2
Malek, R.L.3
-
39
-
-
11144355973
-
Autocrine stimulation by osteopontin plays a pivotal role in the expression of the mitogenic and invasive phenotype of RET/PTC-transformed thyroid cells
-
Castellone MD, Celetti A, Guarino V, et al. Autocrine stimulation by osteopontin plays a pivotal role in the expression of the mitogenic and invasive phenotype of RET/PTC-transformed thyroid cells. Oncogene 2004;23:2188-96.
-
(2004)
Oncogene
, vol.23
, pp. 2188-2196
-
-
Castellone, M.D.1
Celetti, A.2
Guarino, V.3
|