-
1
-
-
78649908758
-
National institute of health GWAS website
-
National institute of health GWAS website. , http://www.genome.gov/GWAStudies/
-
-
-
-
2
-
-
55549147191
-
The case of the missing heritability
-
10.1038/456018a, 18987709
-
Maher B. The case of the missing heritability. Nature 2008, 456:18-21. 10.1038/456018a, 18987709.
-
(2008)
Nature
, vol.456
, pp. 18-21
-
-
Maher, B.1
-
3
-
-
33847759937
-
Schizophrenia: a common disease caused by multiple rare alleles
-
10.1192/bjp.bp.106.025585, 17329737
-
McClellan J, Sussier E, King M. Schizophrenia: a common disease caused by multiple rare alleles. British Journal of Psychiatry 2007, 190:194-199. 10.1192/bjp.bp.106.025585, 17329737.
-
(2007)
British Journal of Psychiatry
, vol.190
, pp. 194-199
-
-
McClellan, J.1
Sussier, E.2
King, M.3
-
4
-
-
57049184635
-
Missing data imputation and haplotype phase inference for genome-wide association studies
-
10.1007/s00439-008-0568-7, 2731769, 18850115
-
Browning S. Missing data imputation and haplotype phase inference for genome-wide association studies. Hum Genet 2008, 124:439-450. 10.1007/s00439-008-0568-7, 2731769, 18850115.
-
(2008)
Hum Genet
, vol.124
, pp. 439-450
-
-
Browning, S.1
-
5
-
-
84872976442
-
1000 Genomes project website
-
1000 Genomes project website. , http://www.1000genomes.org
-
-
-
-
6
-
-
42249087793
-
Estimation of significance thresholds for genomewide association scans
-
10.1002/gepi.20297, 2573032,2573032, 18300295
-
Dudbridge F, Gusnanto A. Estimation of significance thresholds for genomewide association scans. Genetic Epidemiology 2008, 32:227-234. 10.1002/gepi.20297, 2573032,2573032, 18300295.
-
(2008)
Genetic Epidemiology
, vol.32
, pp. 227-234
-
-
Dudbridge, F.1
Gusnanto, A.2
-
7
-
-
39649108872
-
Genome-wide significance for dense SNP and resequencing data
-
10.1002/gepi.20292, 18200594
-
Hoggart C, Clark T, De Iorio M, Whittaker J, Balding D. Genome-wide significance for dense SNP and resequencing data. Genetic Epidemiology 2008, 32:179-185. 10.1002/gepi.20292, 18200594.
-
(2008)
Genetic Epidemiology
, vol.32
, pp. 179-185
-
-
Hoggart, C.1
Clark, T.2
De Iorio, M.3
Whittaker, J.4
Balding, D.5
-
8
-
-
0344033602
-
Detecting disease associations due to linkage disequilibrium using haplotype tags: a class of tests and the determinants of statistical power
-
10.1159/000073729, 14614235
-
Chapman J, Cooper JD, Todd TA, Clayton D. Detecting disease associations due to linkage disequilibrium using haplotype tags: a class of tests and the determinants of statistical power. Hum Hered 2003, 56:18-31. 10.1159/000073729, 14614235.
-
(2003)
Hum Hered
, vol.56
, pp. 18-31
-
-
Chapman, J.1
Cooper, J.D.2
Todd, T.A.3
Clayton, D.4
-
9
-
-
10044279127
-
Use of unphased multilocus genotype data in indirect association studies
-
10.1002/gepi.20032, 15481099
-
Clayton D, Chapman J, Cooper J. Use of unphased multilocus genotype data in indirect association studies. Genetic Epidemiology 2004, 27:415-428. 10.1002/gepi.20032, 15481099.
-
(2004)
Genetic Epidemiology
, vol.27
, pp. 415-428
-
-
Clayton, D.1
Chapman, J.2
Cooper, J.3
-
10
-
-
33748804424
-
A tutorial on statistical methods for population association studies
-
10.1038/nrg1916, 16983374
-
Balding D. A tutorial on statistical methods for population association studies. Nature Reviews Genetics 2006, 7:781-791. 10.1038/nrg1916, 16983374.
-
(2006)
Nature Reviews Genetics
, vol.7
, pp. 781-791
-
-
Balding, D.1
-
11
-
-
43249118858
-
Measuring and partitioning the high-order linkage disequilibrium by multiple order Markov chains
-
10.1002/gepi.20305, 18330903
-
Kim Y, Feng S, Zeng Z. Measuring and partitioning the high-order linkage disequilibrium by multiple order Markov chains. Genetic Epidemiology 2008, 32:301-312. 10.1002/gepi.20305, 18330903.
-
(2008)
Genetic Epidemiology
, vol.32
, pp. 301-312
-
-
Kim, Y.1
Feng, S.2
Zeng, Z.3
-
12
-
-
30344466239
-
Fine-scale mapping in case-control samples using locus scoring and haplotype-sharing methods
-
10.1186/1471-2156-6-S1-S74, 545062, 15634360
-
Humphreys K, Iles M. Fine-scale mapping in case-control samples using locus scoring and haplotype-sharing methods. BMC Genet 2005, 6(Suppl 1):1-5. 10.1186/1471-2156-6-S1-S74, 545062, 15634360.
-
(2005)
BMC Genet
, vol.6
, Issue.SUPPL 1
, pp. 1-5
-
-
Humphreys, K.1
Iles, M.2
-
13
-
-
0033358595
-
Transmission/Disequilibrium tests for extended marker haplotypes
-
Clayton D, Jones H. Transmission/Disequilibrium tests for extended marker haplotypes. Am J Hum Gen 1999, 65:1161-1169.
-
(1999)
Am J Hum Gen
, vol.65
, pp. 1161-1169
-
-
Clayton, D.1
Jones, H.2
-
14
-
-
33746512512
-
Principal componenents analysis corrects for stratification in genome-wide association studies
-
10.1038/ng1847, 16862161
-
Price A, Patterson N, et al. Principal componenents analysis corrects for stratification in genome-wide association studies. Nature genetics 2006, 38:904-909. 10.1038/ng1847, 16862161.
-
(2006)
Nature genetics
, vol.38
, pp. 904-909
-
-
Price, A.1
Patterson, N.2
-
16
-
-
68449096727
-
Common variants on chromosome 6p22.1 are associated with schizophrenia
-
2775422, 19571809
-
Shi J, Levinson D, Duan J, et al. Common variants on chromosome 6p22.1 are associated with schizophrenia. Nature 2009, 460:753-757. 2775422, 19571809.
-
(2009)
Nature
, vol.460
, pp. 753-757
-
-
Shi, J.1
Levinson, D.2
Duan, J.3
-
17
-
-
27544497650
-
Calibrating a coalescent simulation of human genome sequence variation
-
10.1101/gr.3709305, 1310645, 16251467
-
Schaffner S, Foo C, Gabriel S, Reich D, Daly MJ, Altshuler D. Calibrating a coalescent simulation of human genome sequence variation. Genome Research 2005, 15:1576-1583. 10.1101/gr.3709305, 1310645, 16251467.
-
(2005)
Genome Research
, vol.15
, pp. 1576-1583
-
-
Schaffner, S.1
Foo, C.2
Gabriel, S.3
Reich, D.4
Daly, M.J.5
Altshuler, D.6
-
18
-
-
0036284203
-
Testing association of statistically inferred haplotypes with discrete and continuous traits in samples of unrelated individuals
-
Zaykin D, Westfall P, Young S, Karnoub M, Wagner M, Ehm M. Testing association of statistically inferred haplotypes with discrete and continuous traits in samples of unrelated individuals. Hum Hered 2001, 53:79-91.
-
(2001)
Hum Hered
, vol.53
, pp. 79-91
-
-
Zaykin, D.1
Westfall, P.2
Young, S.3
Karnoub, M.4
Wagner, M.5
Ehm, M.6
-
19
-
-
67149093174
-
A kinship-based modification of the Armitage trend test to address hidden population structure and small differential genotyping errors
-
10.1371/journal.pone.0005825, 2688076, 19503792
-
Rakovski C, Stram D. A kinship-based modification of the Armitage trend test to address hidden population structure and small differential genotyping errors. PLoS one 2009, 4:e5825. 10.1371/journal.pone.0005825, 2688076, 19503792.
-
(2009)
PLoS one
, vol.4
-
-
Rakovski, C.1
Stram, D.2
-
20
-
-
34548292504
-
PLINK: a toolset for whole-genome association and population-based linkage analysis
-
Purcell S, et al. PLINK: a toolset for whole-genome association and population-based linkage analysis. Am J Hum Gen 2007, 81:559-575.
-
(2007)
Am J Hum Gen
, vol.81
, pp. 559-575
-
-
Purcell, S.1
-
21
-
-
77955166399
-
Population structure and cryptic relatedness in genetic association studies
-
Astle W, Balding D. Population structure and cryptic relatedness in genetic association studies. Statistical Science 2009, 24:451-471.
-
(2009)
Statistical Science
, vol.24
, pp. 451-471
-
-
Astle, W.1
Balding, D.2
-
22
-
-
41649094148
-
Likelihood-based association analysis for nuclear and unrelated subjects with missing genotype data
-
10.1159/000119108, 2386559, 18382088
-
Dudbridge F. Likelihood-based association analysis for nuclear and unrelated subjects with missing genotype data. Human Heredity 2008, 66:87-98. 10.1159/000119108, 2386559, 18382088.
-
(2008)
Human Heredity
, vol.66
, pp. 87-98
-
-
Dudbridge, F.1
-
23
-
-
35348817330
-
Rapid and accurate haplotype phasing and missing data inference for whole-genome association studies by use of localized haplotype clustering
-
Browning S, Browning B. Rapid and accurate haplotype phasing and missing data inference for whole-genome association studies by use of localized haplotype clustering. Am J Hum Gen 2007, 81:1084-1097.
-
(2007)
Am J Hum Gen
, vol.81
, pp. 1084-1097
-
-
Browning, S.1
Browning, B.2
-
24
-
-
33947701533
-
One degree of freedom for dominance in indirect association studies
-
10.1002/gepi.20207, 17266117
-
Chapman J, Clayton D. One degree of freedom for dominance in indirect association studies. Genetic Epidemiology 2007, 31:261-271. 10.1002/gepi.20207, 17266117.
-
(2007)
Genetic Epidemiology
, vol.31
, pp. 261-271
-
-
Chapman, J.1
Clayton, D.2
-
25
-
-
0030474271
-
A simulation study of the number of events per variable in logistic regression analysis
-
Peduzzi P, Concato J, Kemper E, Holford T, Feinstein A. A simulation study of the number of events per variable in logistic regression analysis. J Clin Epidemiol 1996, 12:1373-1379.
-
(1996)
J Clin Epidemiol
, vol.12
, pp. 1373-1379
-
-
Peduzzi, P.1
Concato, J.2
Kemper, E.3
Holford, T.4
Feinstein, A.5
-
26
-
-
3042591234
-
Linkage disequilibrium mapping via cladistic analysis of single-nucleotide polymorphism haplotypes
-
Durrant C, Zondervan K, Cardon L, Hunt S, Deloukas P, Morris A. Linkage disequilibrium mapping via cladistic analysis of single-nucleotide polymorphism haplotypes. Am J Hum Gen 2004, 75:35-43.
-
(2004)
Am J Hum Gen
, vol.75
, pp. 35-43
-
-
Durrant, C.1
Zondervan, K.2
Cardon, L.3
Hunt, S.4
Deloukas, P.5
Morris, A.6
-
28
-
-
33749037699
-
A flexible Bayesian framework for modelling haplotype association with disease, allowing for dominance effects of the underlying causative variants
-
10.1086/508264, 1592560, 16960804
-
Morris A. A flexible Bayesian framework for modelling haplotype association with disease, allowing for dominance effects of the underlying causative variants. Am J Hum Genet 2006, 79:679-694. 10.1086/508264, 1592560, 16960804.
-
(2006)
Am J Hum Genet
, vol.79
, pp. 679-694
-
-
Morris, A.1
-
29
-
-
34547638844
-
Genetic association mapping via evolution-based clustering of haplotypes
-
Tachmazidou I, Verzilli C, De Iorio M. Genetic association mapping via evolution-based clustering of haplotypes. PLoS Genetics 2004, 3:1163-1177.
-
(2004)
PLoS Genetics
, vol.3
, pp. 1163-1177
-
-
Tachmazidou, I.1
Verzilli, C.2
De Iorio, M.3
-
30
-
-
0142156650
-
Modeling and E-M estimation of haplotype specific relative risks from genotype data for a case-control study of unrelated individuals
-
10.1159/000073202, 14566096
-
Stram D, et al. Modeling and E-M estimation of haplotype specific relative risks from genotype data for a case-control study of unrelated individuals. Hum Hered 2003, 55:179-190. 10.1159/000073202, 14566096.
-
(2003)
Hum Hered
, vol.55
, pp. 179-190
-
-
Stram, D.1
-
31
-
-
15544366469
-
Accounting for haplotype uncertainty in matched association studies: a comparison of simple and flexible techniques
-
10.1002/gepi.20061, 15637718
-
Kraft P, Cox D, Paynter R, Hunter D, De Vivo I. Accounting for haplotype uncertainty in matched association studies: a comparison of simple and flexible techniques. Genetic Epidemiology 2005, 28:261-272. 10.1002/gepi.20061, 15637718.
-
(2005)
Genetic Epidemiology
, vol.28
, pp. 261-272
-
-
Kraft, P.1
Cox, D.2
Paynter, R.3
Hunter, D.4
De Vivo, I.5
-
32
-
-
33645465693
-
Estimation and testing of genotype and haplotype effects in case-control studies: comparison of weighted regression and multiple imputation procedures
-
10.1002/gepi.20142, 16496312
-
Cordell H. Estimation and testing of genotype and haplotype effects in case-control studies: comparison of weighted regression and multiple imputation procedures. Genetic Epidemiology 2006, 30:259-275. 10.1002/gepi.20142, 16496312.
-
(2006)
Genetic Epidemiology
, vol.30
, pp. 259-275
-
-
Cordell, H.1
-
33
-
-
0029130796
-
Maximum likelihood estimation of molecular haplotype frequencies in a diploid population
-
Excoffier L, Slatkin M. Maximum likelihood estimation of molecular haplotype frequencies in a diploid population. Mol Biol Evol 1995, 12:921-927.
-
(1995)
Mol Biol Evol
, vol.12
, pp. 921-927
-
-
Excoffier, L.1
Slatkin, M.2
-
34
-
-
0003167173
-
Robust properties of likelihood ratio tests
-
Kent J. Robust properties of likelihood ratio tests. Biometrika 1982, 69:19-27.
-
(1982)
Biometrika
, vol.69
, pp. 19-27
-
-
Kent, J.1
-
35
-
-
0002394561
-
Large sample tests of statistical hypotheses concerning several parameters with applications to problems of estimation
-
Rao CR. Large sample tests of statistical hypotheses concerning several parameters with applications to problems of estimation. Proc Camb Phil 1948, 44:50.
-
(1948)
Proc Camb Phil
, vol.44
, pp. 50
-
-
Rao, C.R.1
-
36
-
-
0036137030
-
A unified stepwise regression procedure for evaluating the relative effects of polymorphisms within a gene using case/control or family data: application to HLA in type 1 diabetes
-
10.1086/338007, 384883, 11719900
-
Cordell H, Clayton D. A unified stepwise regression procedure for evaluating the relative effects of polymorphisms within a gene using case/control or family data: application to HLA in type 1 diabetes. Am J Hum Genet 2002, 70:124-141. 10.1086/338007, 384883, 11719900.
-
(2002)
Am J Hum Genet
, vol.70
, pp. 124-141
-
-
Cordell, H.1
Clayton, D.2
-
37
-
-
0029199341
-
A method for quantifying differentiation between populations a multi-allelicloci and its implications for investigating identity and paternity
-
10.1007/BF01441146, 7607457
-
Balding D, Nichols R. A method for quantifying differentiation between populations a multi-allelicloci and its implications for investigating identity and paternity. Genetica 1995, 96:3-12. 10.1007/BF01441146, 7607457.
-
(1995)
Genetica
, vol.96
, pp. 3-12
-
-
Balding, D.1
Nichols, R.2
-
39
-
-
0032714352
-
Genomic control for association studies
-
10.1111/j.0006-341X.1999.00997.x, 11315092
-
Devlin B, Roeder K. Genomic control for association studies. Biometrics 1999, 55:997-1004. 10.1111/j.0006-341X.1999.00997.x, 11315092.
-
(1999)
Biometrics
, vol.55
, pp. 997-1004
-
-
Devlin, B.1
Roeder, K.2
-
40
-
-
42349112088
-
Genome-wide association studies for complex traits: consensus, uncertainty and challenges
-
10.1038/nrg2344, 18398418
-
McCarthy M, Abecasis G, et al. Genome-wide association studies for complex traits: consensus, uncertainty and challenges. Nature Reviews Genetics 2008, 9:356-369. 10.1038/nrg2344, 18398418.
-
(2008)
Nature Reviews Genetics
, vol.9
, pp. 356-369
-
-
McCarthy, M.1
Abecasis, G.2
-
41
-
-
84969213492
-
Genome-wide association study of 14000 cases of seven common diseases and 3000 shared controls
-
10.1038/nature05911, 2719288, 17554300
-
Genome-wide association study of 14000 cases of seven common diseases and 3000 shared controls. Nature 2007, 447:661-679. 10.1038/nature05911, 2719288, 17554300.
-
(2007)
Nature
, vol.447
, pp. 661-679
-
-
-
42
-
-
27644546712
-
Population structure, differential bias and genomic control in a large-scale, case-control association study
-
10.1038/ng1653, 16228001
-
Clayon D, Walker N, et al. Population structure, differential bias and genomic control in a large-scale, case-control association study. Nature Genetics 2005, 37:1243-1246. 10.1038/ng1653, 16228001.
-
(2005)
Nature Genetics
, vol.37
, pp. 1243-1246
-
-
Clayon, D.1
Walker, N.2
|