Apogossypolone, a novel inhibitor of antiapoptotic Bcl-2 family proteins, induces autophagy of PC-3 and LNCaP prostate cancer cells in vitro

Asian Journal of Andrology

Volumn 12, Issue 5, 2010, Pages 697-708

  Zhang, Xian Qing ^a   Huang, Xiao Feng ^b   Hu, Xing Bin ^a   Zhan, Yong Hua ^a   An, Qun Xing ^a   Yang, Shi Ming ^c   Xia, Ai Jun ^a   Yi, Jing ^a   Chen, Rui ^a   Mu, Shi Jie ^a   Wu, Dao Cheng ^d  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c XIDIAN UNIVERSITY   (China)

^d XI'AN JIAOTONG UNIVERSITY   (China)

Author keywords

apogossypolone; apoptosis; autophagy; prostate cancer

Indexed keywords

3 METHYLADENINE; ANTINEOPLASTIC AGENT; APOGOSSYPOLONE; BECLIN 1; GOSSYPOL; PROTEIN INHIBITOR; UNCLASSIFIED DRUG;

ACID VESICULAR ORGANELLE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL ORGANELLE; CELL STRAIN LNCAP; CELL VACUOLE; CONTROLLED STUDY; CYTOPLASM; HUMAN; HUMAN CELL; IN VITRO STUDY; PROTEIN EXPRESSION;

ADENINE; ANTINEOPLASTIC AGENTS; APOPTOSIS; AUTOPHAGY; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; GOSSYPOL; GROWTH INHIBITORS; HUMANS; MALE; PROSTATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 77956424866     PISSN: 1008682X     EISSN: 17457262     Source Type: Journal    
DOI: 10.1038/aja.2010.57     Document Type: Article

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