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Volumn 7, Issue , 2008, Pages
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Preclinical studies of apogossypolone: A new nonpeptidic pan small-molecule inhibitor of Bcl-2, Bcl-XL and Mcl-1 proteins in Follicular Small Cleaved Cell Lymphoma model
a
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Author keywords
[No Author keywords available]
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Indexed keywords
APOGOSSYPOLONE;
APOPTOSIS INDUCING FACTOR;
CASPASE 3;
CASPASE 8;
CASPASE 9;
NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE;
PROTEIN BCL 2;
PROTEIN BCL XL;
PROTEIN INHIBITOR;
PROTEIN MCL 1;
UNCLASSIFIED DRUG;
ANTINEOPLASTIC AGENT;
APOPTOSIS REGULATORY PROTEIN;
CASPASE;
GOSSYPOL;
MCL1 PROTEIN;
PROTEIN BCL X;
TUMOR PROTEIN;
ANIMAL EXPERIMENT;
ANIMAL MODEL;
ANIMAL TISSUE;
ARTICLE;
CELL GROWTH;
CELL ISOLATION;
CONTROLLED STUDY;
DRUG STRUCTURE;
ENZYME INHIBITION;
FEMALE;
FOLLICULAR LYMPHOMA;
GROWTH INHIBITION;
HUMAN;
HUMAN CELL;
IC 50;
LYMPHOMA CELL LINE;
MOUSE;
NONHUMAN;
PROTEIN EXPRESSION;
PROTEIN FAMILY;
PROTEIN TARGETING;
SURVIVAL RATE;
TUMOR XENOGRAFT;
ANIMAL;
BONE MARROW;
CELL SURVIVAL;
CHEMISTRY;
DRUG ANTAGONISM;
DRUG EFFECT;
DRUG SCREENING;
ENZYME ACTIVATION;
ENZYMOLOGY;
LYMPHOCYTE;
METABOLISM;
MOUSE MUTANT;
PATHOLOGY;
SURVIVAL;
TUMOR CELL LINE;
MUS;
ANIMALS;
ANTINEOPLASTIC AGENTS;
APOPTOSIS REGULATORY PROTEINS;
BCL-X PROTEIN;
BONE MARROW;
CASPASES;
CELL LINE, TUMOR;
CELL SURVIVAL;
DRUG EVALUATION, PRECLINICAL;
ENZYME ACTIVATION;
FEMALE;
GOSSYPOL;
HUMANS;
INHIBITORY CONCENTRATION 50;
LYMPHOCYTES;
LYMPHOMA, FOLLICULAR;
MICE;
MICE, SCID;
NEOPLASM PROTEINS;
POLY(ADP-RIBOSE) POLYMERASES;
PROTO-ONCOGENE PROTEINS C-BCL-2;
SURVIVAL ANALYSIS;
XENOGRAFT MODEL ANTITUMOR ASSAYS;
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EID: 40549146581
PISSN: None
EISSN: 14764598
Source Type: Journal
DOI: 10.1186/1476-4598-7-20 Document Type: Article |
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Times cited : (83)
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References (39)
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