-
1
-
-
14844361808
-
Multisite protein modification and intramolecular signaling
-
Yang XJ: Multisite protein modification and intramolecular signaling . Oncogene 2005 ; 24: 1653-1662 .
-
(2005)
Oncogene
, vol.24
, pp. 1653-1662
-
-
Yang, X.J.1
-
2
-
-
0037032835
-
The protein kinase complement of the human genome
-
Manning G , Whyte DB , Martinez R , Hunter T , Sudarsanam S: The protein kinase complement of the human genome . Science 2002 ; 298: 1912-1934 .
-
(2002)
Science
, vol.298
, pp. 1912-1934
-
-
Manning, G.1
Whyte, D.B.2
Martinez, R.3
Hunter, T.4
Sudarsanam, S.5
-
3
-
-
0034693799
-
The protein tyrosine kinase family of the human genome
-
Robinson DR , Wu YM , Lin SF: The protein tyrosine kinase family of the human genome . Oncogene 2000 ; 19: 5548-5557 .
-
(2000)
Oncogene
, vol.19
, pp. 5548-5557
-
-
Robinson, D.R.1
Wu, Y.M.2
Lin, S.F.3
-
4
-
-
0031439247
-
Cellular functions regulated by Src family kinases
-
Thomas SM , Brugge JS: Cellular functions regulated by Src family kinases . Annu Rev Cell Dev Biol 1997 ; 13: 513-609 .
-
(1997)
Annu Rev Cell Dev Biol
, vol.13
, pp. 513-609
-
-
Thomas, S.M.1
Brugge, J.S.2
-
5
-
-
7944236785
-
Src family kinases, key regulators of signal transduction
-
Parsons SJ , Parsons JT: Src family kinases, key regulators of signal transduction . Oncogene 2004 ; 23: 7906-7909 .
-
(2004)
Oncogene
, vol.23
, pp. 7906-7909
-
-
Parsons, S.J.1
Parsons, J.T.2
-
6
-
-
7944223078
-
Structure and regulation of Src family kinases
-
Boggon TJ , Eck MJ: Structure and regulation of Src family kinases . Oncogene 2004 ; 23: 7918-7927 .
-
(2004)
Oncogene
, vol.23
, pp. 7918-7927
-
-
Boggon, T.J.1
Eck, M.J.2
-
7
-
-
0031452274
-
Structures of Src-family tyrosine kinases
-
Sicheri F , Kuriyan J: Structures of Src-family tyrosine kinases . Curr Opin Struct Biol 1997 ; 7: 777-785 .
-
(1997)
Curr Opin Struct Biol
, vol.7
, pp. 777-785
-
-
Sicheri, F.1
Kuriyan, J.2
-
8
-
-
0030293791
-
Alpha beta T cell development is abolished in mice lacking both Lck and Fyn protein tyrosine kinases
-
van Oers NS , Lowin-Kropf B , Finlay D , Connolly K , Weiss A: alpha beta T cell development is abolished in mice lacking both Lck and Fyn protein tyrosine kinases . Immunity 1996 ; 5: 429-436 .
-
(1996)
Immunity
, vol.5
, pp. 429-436
-
-
Van Oers, N.S.1
Lowin-Kropf, B.2
Finlay, D.3
Connolly, K.4
Weiss, A.5
-
9
-
-
0026522204
-
Profound block in thymocyte development in mice lacking p56lck
-
Molina TJ , Kishihara K , Siderovski DP , van Ewijk W , Narendran A , Timms E , et al .: Profound block in thymocyte development in mice lacking p56lck . Nature 1992 ; 357: 161-164 .
-
(1992)
Nature
, vol.357
, pp. 161-164
-
-
Molina, T.J.1
Kishihara, K.2
Siderovski, D.P.3
Van Ewijk, W.4
Narendran, A.5
Timms, E.6
-
10
-
-
0028784215
-
Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease
-
Hibbs ML , Tarlinton DM , Armes J , Grail D , Hodgson G , Maglitto R , et al .: Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease . Cell 1995 ; 83: 301-311 .
-
(1995)
Cell
, vol.83
, pp. 301-311
-
-
Hibbs, M.L.1
Tarlinton, D.M.2
Armes, J.3
Grail, D.4
Hodgson, G.5
Maglitto, R.6
-
11
-
-
0037121973
-
Sustained activation of Lyn tyrosine kinase in vivo leads to autoimmunity
-
Hibbs ML , Harder KW , Armes J , Kountouri N , Quilici C, Casagranda F, et al.: Sustained activation of Lyn tyrosine kinase in vivo leads to autoimmunity . J Exp Med 2002 ; 196: 1593-1604 .
-
(2002)
J Exp Med
, vol.196
, pp. 1593-1604
-
-
Hibbs, M.L.1
Harder, K.W.2
Armes, J.3
Kountouri, N.4
Quilici, C.5
Casagranda, F.6
-
12
-
-
0028293147
-
Functional overlap in the src gene family: Inactivation of hck and fgr impairs natural immunity
-
Lowell CA , Soriano P , Varmus HE: Functional overlap in the src gene family: inactivation of hck and fgr impairs natural immunity . Genes Dev 1994 ; 8: 387-398 .
-
(1994)
Genes Dev
, vol.8
, pp. 387-398
-
-
Lowell, C.A.1
Soriano, P.2
Varmus, H.E.3
-
13
-
-
0036715696
-
Constitutive activation of the SRC family kinase Hck results in spontaneous pulmonary inflammation and an enhanced innate immune response
-
Ernst M , Inglese M , Scholz GM , Harder KW , Clay FJ , Bozinovski S , et al .: Constitutive activation of the SRC family kinase Hck results in spontaneous pulmonary inflammation and an enhanced innate immune response . J Exp Med 2002 ; 196: 589-604 .
-
(2002)
J Exp Med
, vol.196
, pp. 589-604
-
-
Ernst, M.1
Inglese, M.2
Scholz, G.M.3
Harder, K.W.4
Clay, F.J.5
Bozinovski, S.6
-
14
-
-
0031882754
-
Activation of extracellular signalregulated kinases (ERK1/2) by angiotensin II is dependent on c-Src in vascular smooth muscle cells
-
Ishida M , Ishida T , Thomas SM , Berk BC: Activation of extracellular signalregulated kinases (ERK1/2) by angiotensin II is dependent on c-Src in vascular smooth muscle cells . Circ Res 1998 ; 82: 7-12 .
-
(1998)
Circ Res
, vol.82
, pp. 7-12
-
-
Ishida, M.1
Ishida, T.2
Thomas, S.M.3
Berk, B.C.4
-
15
-
-
0033559439
-
Agonist-stimulated cytoskeletal reorganization and signal transduction at focal adhesions in vascular smooth muscle cells require c-Src
-
Ishida T , Ishida M , Suero J , Takahashi M , Berk BC: Agonist-stimulated cytoskeletal reorganization and signal transduction at focal adhesions in vascular smooth muscle cells require c-Src . J Clin Invest 1999 ; 103: 789-797 .
-
(1999)
J Clin Invest
, vol.103
, pp. 789-797
-
-
Ishida, T.1
Ishida, M.2
Suero, J.3
Takahashi, M.4
Berk, B.C.5
-
16
-
-
33845317252
-
ANG II-induced cell proliferation is dually mediated by c-Src/Yes/Fyn-regulated ERK1/2 activation in the cytoplasm and PKCzetacontrolled ERK1/2 activity within the nucleus
-
Godeny MD , Sayeski PP: ANG II-induced cell proliferation is dually mediated by c-Src/Yes/Fyn-regulated ERK1/2 activation in the cytoplasm and PKCzetacontrolled ERK1/2 activity within the nucleus . Am J Physiol, Cell Physiol 2006 ; 291: C1297-C1307 .
-
(2006)
Am J Physiol, Cell Physiol
, vol.291
-
-
Godeny, M.D.1
Sayeski, P.P.2
-
17
-
-
0029121267
-
Potentiation of epidermal growth factor receptor-mediated oncogenesis by c-Src: Implications for the etiology of multiple human cancers
-
Maa MC , Leu TH , McCarley DJ , Schatzman RC , Parsons SJ: Potentiation of epidermal growth factor receptor-mediated oncogenesis by c-Src: implications for the etiology of multiple human cancers . Proc Natl Acad Sci USA 1995 ; 92: 6981-6985 .
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 6981-6985
-
-
Maa, M.C.1
Leu, T.H.2
McCarley, D.J.3
Schatzman, R.C.4
Parsons, S.J.5
-
18
-
-
0031025529
-
A role for epidermal growth factor receptor, c-Src and focal adhesion kinase in an in vitro model for the progression of colon cancer
-
Brunton VG , Ozanne BW , Paraskeva C , Frame MC: A role for epidermal growth factor receptor, c-Src and focal adhesion kinase in an in vitro model for the progression of colon cancer . Oncogene 1997 ; 14: 283-293 .
-
(1997)
Oncogene
, vol.14
, pp. 283-293
-
-
Brunton, V.G.1
Ozanne, B.W.2
Paraskeva, C.3
Frame, M.C.4
-
19
-
-
0033573921
-
Mechanism of biological synergy between cellular Src and epidermal growth factor receptor
-
Tice DA , Biscardi JS , Nickles AL , Parsons SJ: Mechanism of biological synergy between cellular Src and epidermal growth factor receptor . Proc Natl Acad Sci USA 1999 ; 96: 1415-1420 .
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 1415-1420
-
-
Tice, D.A.1
Biscardi, J.S.2
Nickles, A.L.3
Parsons, S.J.4
-
20
-
-
22544465537
-
Lyndeficient mice develop severe, persistent asthma: Lyn is a critical negative regulator of Th2 immunity
-
Beavitt SJ , Harder KW , Kemp JM , Jones J , Quilici C , Casagranda F , et al .: Lyndeficient mice develop severe, persistent asthma: Lyn is a critical negative regulator of Th2 immunity . J Immunol 2005 ; 175: 1867-1875 .
-
(2005)
J Immunol
, vol.175
, pp. 1867-1875
-
-
Beavitt, S.J.1
Harder, K.W.2
Kemp, J.M.3
Jones, J.4
Quilici, C.5
Casagranda, F.6
-
21
-
-
0027469402
-
Increase in activity and level of pp60c-src in progressive stages of human colorectal cancer
-
Talamonti MS , Roh MS , Curley SA , Gallick GE: Increase in activity and level of pp60c-src in progressive stages of human colorectal cancer . J Clin Invest 1993 ; 91: 53-60 .
-
(1993)
J Clin Invest
, vol.91
, pp. 53-60
-
-
Talamonti, M.S.1
Roh, M.S.2
Curley, S.A.3
Gallick, G.E.4
-
22
-
-
0032932248
-
Activating SRC mutation in a subset of advanced human colon cancers
-
Irby RB , Mao W , Coppola D , Kang J , Loubeau JM , Trudeau W , et al .: Activating SRC mutation in a subset of advanced human colon cancers . Nat Genet 1999 ; 21: 187-190 .
-
(1999)
Nat Genet
, vol.21
, pp. 187-190
-
-
Irby, R.B.1
Mao, W.2
Coppola, D.3
Kang, J.4
Loubeau, J.M.5
Trudeau, W.6
-
23
-
-
6844259884
-
Activation of c-Src by receptor tyrosine kinases in human colon cancer cells with high metastatic potential
-
Mao W , Irby R , Coppola D , Fu L , Wloch M, Turner J, et al.: Activation of c-Src by receptor tyrosine kinases in human colon cancer cells with high metastatic potential . Oncogene 1997 ; 15: 3083-3090 .
-
(1997)
Oncogene
, vol.15
, pp. 3083-3090
-
-
Mao, W.1
Irby, R.2
Coppola, D.3
Fu, L.4
Wloch, M.5
Turner, J.6
-
24
-
-
0037229627
-
Activated SRC protein tyrosine kinase is overexpressed in late-stage human ovarian cancers
-
Wiener JR, Windham TC, Estrella VC, Parikh NU, Thall PF, Deavers MT, et al.: Activated SRC protein tyrosine kinase is overexpressed in late-stage human ovarian cancers . Gynecol Oncol 2003 ; 88: 73-79 .
-
(2003)
Gynecol Oncol
, vol.88
, pp. 73-79
-
-
Wiener, J.R.1
Windham, T.C.2
Estrella, V.C.3
Parikh, N.U.4
Thall, P.F.5
Deavers, M.T.6
-
25
-
-
17344371665
-
Pp60csrc activation in hepatocellular carcinoma of humans and LEC rats
-
Masaki T , Okada M , Shiratori Y , Rengifo W , Matsumoto K , Maeda S , et al .: pp60csrc activation in hepatocellular carcinoma of humans and LEC rats . Hepatology 1998 ; 27: 1257-1264 .
-
(1998)
Hepatology
, vol.27
, pp. 1257-1264
-
-
Masaki, T.1
Okada, M.2
Shiratori, Y.3
Rengifo, W.4
Matsumoto, K.5
Maeda, S.6
-
26
-
-
40649125574
-
Cell growth, global phosphotyrosine elevation, and c-Met phosphorylation through Src family kinases in colorectal cancer cells
-
Emaduddin M , Bicknell DC , Bodmer WF , Feller SM: Cell growth, global phosphotyrosine elevation, and c-Met phosphorylation through Src family kinases in colorectal cancer cells . Proc Natl Acad Sci USA 2008 ; 105: 2358-2362 .
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 2358-2362
-
-
Emaduddin, M.1
Bicknell, D.C.2
Bodmer, W.F.3
Feller, S.M.4
-
27
-
-
0032560522
-
Malignant transformation of early lymphoid progenitors in mice expressing an activated Blk tyrosine kinase
-
Malek SN , Dordai DI , Reim J , Dintzis H , Desiderio S: Malignant transformation of early lymphoid progenitors in mice expressing an activated Blk tyrosine kinase . Proc Natl Acad Sci USA 1998 ; 95: 7351-7356 .
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 7351-7356
-
-
Malek, S.N.1
Dordai, D.I.2
Reim, J.3
Dintzis, H.4
Desiderio, S.5
-
28
-
-
2942618768
-
A renaissance for SRC
-
Yeatman TJ: A renaissance for SRC . Nat Rev Cancer 2004 ; 4: 470-480 .
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 470-480
-
-
Yeatman, T.J.1
-
29
-
-
33645705918
-
Multiplex analysis of intracellular signaling pathways in lymphoid cells by microbead suspension arrays
-
Khan IH, Mendoza S, Rhyne P, Ziman M, Tuscano J, Eisinger D, et al.: Multiplex analysis of intracellular signaling pathways in lymphoid cells by microbead suspension arrays . Mol Cell Proteomics 2006 ; 5: 758-768 .
-
(2006)
Mol Cell Proteomics
, vol.5
, pp. 758-768
-
-
Khan, I.H.1
Mendoza, S.2
Rhyne, P.3
Ziman, M.4
Tuscano, J.5
Eisinger, D.6
-
30
-
-
33645129863
-
Simultaneous detection of antibodies to six nonhuman-primate viruses by multiplex microbead immunoassay
-
Khan IH, Mendoza S, Yee J, Deane M, Venkateswaran K, Zhou SS, et al.: Simultaneous detection of antibodies to six nonhuman-primate viruses by multiplex microbead immunoassay . Clin Vaccine Immunol 2006 ; 13: 45-52 .
-
(2006)
Clin Vaccine Immunol
, vol.13
, pp. 45-52
-
-
Khan, I.H.1
Mendoza, S.2
Yee, J.3
Deane, M.4
Venkateswaran, K.5
Zhou, S.S.6
-
31
-
-
22844437882
-
Simultaneous serodetection of 10 highly prevalent mouse infectious pathogens in a single reaction by multiplex analysis
-
Khan IH , Kendall LV , Ziman M , Wong S , Mendoza S , Fahey J , et al .: Simultaneous serodetection of 10 highly prevalent mouse infectious pathogens in a single reaction by multiplex analysis . Clin Diagn Lab Immunol 2005 ; 12: 513-519 .
-
(2005)
Clin Diagn Lab Immunol
, vol.12
, pp. 513-519
-
-
Khan, I.H.1
Kendall, L.V.2
Ziman, M.3
Wong, S.4
Mendoza, S.5
Fahey, J.6
-
32
-
-
0030029143
-
Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation
-
Hanke JH , Gardner JP , Dow RL , Changelian PS , Brissette WH , Weringer EJ , et al .: Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation . J Biol Chem 1996 ; 271: 695-701 .
-
(1996)
J Biol Chem
, vol.271
, pp. 695-701
-
-
Hanke, J.H.1
Gardner, J.P.2
Dow, R.L.3
Changelian, P.S.4
Brissette, W.H.5
Weringer, E.J.6
-
33
-
-
17444374230
-
Src kinase regulation by phosphorylation and dephosphorylation
-
Roskoski R , Jr: Src kinase regulation by phosphorylation and dephosphorylation . Biochem Biophys Res Commun 2005 ; 331: 1-14 .
-
(2005)
Biochem Biophys Res Commun
, vol.331
, pp. 1-14
-
-
Roskoski Jr., R.1
-
34
-
-
61849136595
-
CD45, CD148, and Lyp/Pep: Critical phosphatases regulating Src family kinase signaling networks in immune cells
-
Hermiston ML , Zikherman J , Zhu JW: CD45, CD148, and Lyp/Pep: critical phosphatases regulating Src family kinase signaling networks in immune cells . Immunol Rev 2009 ; 228: 288-311 .
-
(2009)
Immunol Rev
, vol.228
, pp. 288-311
-
-
Hermiston, M.L.1
Zikherman, J.2
Zhu, J.W.3
-
35
-
-
3042522852
-
B cell antigen receptor signaling 101
-
Dal Porto JM , Gauld SB , Merrell KT , Mills D , Pugh-Bernard AE , Cambier J: B cell antigen receptor signaling 101 . Mol Immunol 2004 ; 41: 599-613 .
-
(2004)
Mol Immunol
, vol.41
, pp. 599-613
-
-
Dal Porto, J.M.1
Gauld, S.B.2
Merrell, K.T.3
Mills, D.4
Pugh-Bernard, A.E.5
Cambier, J.6
-
36
-
-
61849141064
-
Tyrosine kinases and their substrates in B lymphocytes
-
Kurosaki T , Hikida M . Tyrosine kinases and their substrates in B lymphocytes . Immunol Rev 2009 ; 228: 132-148 .
-
(2009)
Immunol Rev
, vol.228
, pp. 132-148
-
-
Kurosaki, T.1
Hikida, M.2
-
37
-
-
0025739498
-
Anti-immunoglobulin stimulation of B lymphocytes activates src-related protein-tyrosine kinases
-
Burkhardt AL , Brunswick M , Bolen JB , Mond JJ: Anti-immunoglobulin stimulation of B lymphocytes activates src-related protein-tyrosine kinases . Proc Natl Acad Sci USA 1991 ; 88: 7410-7414 .
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 7410-7414
-
-
Burkhardt, A.L.1
Brunswick, M.2
Bolen, J.B.3
Mond, J.J.4
-
38
-
-
0026637001
-
Association between B-lymphocyte membrane immunoglobulin and multiple members of the Src family of protein tyrosine kinases
-
Campbell MA , Sefton BM: Association between B-lymphocyte membrane immunoglobulin and multiple members of the Src family of protein tyrosine kinases . Mol Cell Biol 1992 ; 12: 2315-2321 .
-
(1992)
Mol Cell Biol
, vol.12
, pp. 2315-2321
-
-
Campbell, M.A.1
Sefton, B.M.2
-
39
-
-
0028987576
-
Src-family tyrosine kinase p55fgr is expressed in murine splenic B cells and is activated in response to antigen receptor crosslinking
-
Wechsler RJ , Monroe JG: src-family tyrosine kinase p55fgr is expressed in murine splenic B cells and is activated in response to antigen receptor crosslinking . J Immunol 1995 ; 154: 3234-3244 .
-
(1995)
J Immunol
, vol.154
, pp. 3234-3244
-
-
Wechsler, R.J.1
Monroe, J.G.2
-
40
-
-
0025873239
-
B lymphocyte activation is accompanied by phosphorylation of a 72-kDa protein-tyrosine kinase
-
Hutchcroft JE , Harrison ML , Geahlen RL: B lymphocyte activation is accompanied by phosphorylation of a 72-kDa protein-tyrosine kinase . J Biol Chem 1991 ; 266: 14846-14849 .
-
(1991)
J Biol Chem
, vol.266
, pp. 14846-14849
-
-
Hutchcroft, J.E.1
Harrison, M.L.2
Geahlen, R.L.3
-
41
-
-
60149089005
-
Beadbased profiling of tyrosine kinase phosphorylation identifies SRC as a potential target for glioblastoma therapy
-
Du J , Bernasconi P , Clauser KR , Mani DR , Finn SP , Beroukhim R , et al .: Beadbased profiling of tyrosine kinase phosphorylation identifies SRC as a potential target for glioblastoma therapy . Nat Biotechnol 2009 ; 27: 77-83 .
-
(2009)
Nat Biotechnol
, vol.27
, pp. 77-83
-
-
Du, J.1
Bernasconi, P.2
Clauser, K.R.3
Mani, D.R.4
Finn, S.P.5
Beroukhim, R.6
-
42
-
-
35348822482
-
Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies
-
Stommel JM , Kimmelman AC , Ying H , Nabioullin R , Ponugoti AH , Wiedemeyer R , et al .: Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies . Science 2007 ; 318: 287-290 .
-
(2007)
Science
, vol.318
, pp. 287-290
-
-
Stommel, J.M.1
Kimmelman, A.C.2
Ying, H.3
Nabioullin, R.4
Ponugoti, A.H.5
Wiedemeyer, R.6
-
43
-
-
34249075147
-
MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling
-
Engelman JA , Zejnullahu K , Mitsudomi T , Song Y , Hyland C , Park JO , et al .: MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling . Science 2007 ; 316: 1039-1043 .
-
(2007)
Science
, vol.316
, pp. 1039-1043
-
-
Engelman, J.A.1
Zejnullahu, K.2
Mitsudomi, T.3
Song, Y.4
Hyland, C.5
Park, J.O.6
-
44
-
-
0035848705
-
Reverse phase protein microarrays which capture disease progression show activation of pro-survival pathways at the cancer invasion front
-
Paweletz CP , Charboneau L , Bichsel VE , Simone NL , Chen T , Gillespie JW , et al .: Reverse phase protein microarrays which capture disease progression show activation of pro-survival pathways at the cancer invasion front . Oncogene 2001 ; 20: 1981-1989 .
-
(2001)
Oncogene
, vol.20
, pp. 1981-1989
-
-
Paweletz, C.P.1
Charboneau, L.2
Bichsel, V.E.3
Simone, N.L.4
Chen, T.5
Gillespie, J.W.6
|