Non-adherence to antihypertensive medication and impaired cognition: Which comes first?

International Journal of Pharmacy Practice

Volumn 18, Issue 5, 2010, Pages 252-259

  Gard, Paul R ^a  

^a UNIVERSITY OF BRIGHTON   (United Kingdom)

Author keywords

Alzheimer's disease; angiotensin receptor antagonists; angiotensin converting enzyme inhibitors (ACEIs); dementia; mild cognitive impairment

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; ANTIHYPERTENSIVE AGENT; BENAZEPRIL; CALCIUM CHANNEL BLOCKING AGENT; CAPTOPRIL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENALAPRIL; FOSINOPRIL; LISINOPRIL; MOEXIPRIL; PERINDOPRIL; QUINAPRIL; RAMIPRIL; THIAZIDE DIURETIC AGENT; TRANDOLAPRIL;

ALZHEIMER DISEASE; ANTIHYPERTENSIVE THERAPY; BLOOD PRESSURE REGULATION; COGNITIVE DEFECT; DEMENTIA; DISEASE SEVERITY; DRUG EFFICACY; HUMAN; HYPERTENSION; HYPOTENSION; PATIENT COMPLIANCE; PRACTICE GUIDELINE; PREVALENCE; PRIORITY JOURNAL; REVIEW; AGED; COGNITION DISORDERS; MEDICATION COMPLIANCE; MIDDLE AGED;

AGED; ANTIHYPERTENSIVE AGENTS; COGNITION DISORDERS; GUIDELINES AS TOPIC; HUMANS; HYPERTENSION; MEDICATION ADHERENCE; MIDDLE AGED;

EID: 77956414653     PISSN: 09617671     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.2042-7174.2010.00045.x     Document Type: Review

References (64)

1. Turner BJ et al. Barriers to adherence and hypertension control in a racially diverse representative sample of elderly primary care patients. Pharmacoepidemiol Drug Saf 2009 18 : 672 681.
2. Petersen RC et al. Mild cognitive impairment - clinical characterization and outcome. Arch Neurol 1999 56 : 303 308.
3. Vinyoles E et al. Cognitive function and blood pressure control in hypertensive patients over 60 years of age: COGNIPRES study. Curr Med Res Opin 2008 24 : 3331 3340.
4. Farmer ME et al. Blood-pressure and cognitive performance - the Framingham-study. Am J Epidemiol 1987 126 : 1103 1114.
5. Amenta F et al. Protective effect of anti-hypertensive treatment on cognitive function in essential hypertension: analysis of published clinical data. 2nd International Congress on Vascular Dementia; 24-27 January 2002; Salzburg, Austria: Elsevier Science BV 2002. pp. 147 151.
6. Feigin V et al. Does blood pressure lowering treatment prevents dementia or cognitive decline in patients with cardiovascular and cerebrovascular disease? 3rd International Congress on Vascular Dementia; 23-26 October 2003; Prague, Czech Republic: Elsevier Science BV 2003. pp. 151 155.
7. Kilander L et al. Hypertension is related to cognitive impairment - a 20-year follow-up of 999 men. Hypertension 1998 31 : 780 786.
8. Guo ZC et al. Occurrence and progression of dementia in a community population aged 75 years and older - Relationship of antihypertensive medication use. Arch Neurol 1999 56 : 991 996.
9. Birns J et al. The effects of blood pressure reduction on cognitive function: a review of effects based on pooled data from clinical trials. J Hypertens 2006 24 : 1907 1914.
10. Di Bari M et al. Dementia and disability outcomes in large hypertension trials: lessons learned from the Systolic Hypertension in the Elderly Program (SHEP) trial. Am J Epidemiol 2001 153 : 72 78.
11. Forette F et al. Prevention of dementia in randomised double-blind placebo-controlled Systolic Hypertension in Europe (Syst-Eur) trial. Lancet 1998 352 : 1347 1351.
12. Tzourio C et al. Effects of blood pressure lowering with perindopril and indapamide therapy on dementia and cognitive decline in patients with cerebrovascular disease. Arch Intern Med 2003 163 : 1069 1075.
13. Khachaturian AS et al. Antihypertensive medication use and incident Alzheimer disease - the Cache County Study. Arch Neurol 2006 63 : 686 692.
14. Mogi M, Horiuchi M. Effects of angiotensin II receptor blockers on dementia. Hypertens Res 2009 32 : 738 740.
15. Hanon O et al. Effects of hypertension therapy based on eprosartan on systolic arterial blood pressure and cognitive function: primary results of the Observational Study on Cognitive function And Systolic Blood Pressure Reduction open-label study. J Hypertens 2008 26 : 1642 1650.
16. Lithell H et al. The Study on Cognition and Prognosis in the Elderly (SCOPE): principal results of a randomized double-blind intervention trial. J Hypertens 2003 21 : 875 886. (Pubitemid 36677151)
17. Tedesco MA et al. Does the angiotensin II receptor antagonist losartan improve cognitive function? Drugs Aging 2002 19 : 723 732.
18. Shlyakhto E. Observational Study on Cognitive function And systolic blood pressure Reduction (OSCAR): preliminary analysis of 6-month data from >10 000 patients and review of the literature. 28th Congress of the European-Society-of-Cardiology/World Congress of Cardiology; 2-6 September 2006; Barcelona, Spain: Librapharm/Informa Healthcare 2006. pp. S13 SS8.
19. Mechaeil R et al. The separate and combined effects of losartan and scopolamine on cognitive performance of healthy young adults. Neuroscience; Washington DC 2008. p. 788.4/SS54.
20. Castillo Del P. [Hyperostosis frontalis interna, obesity, polyuria, amenorrhea, arterial hypertension, hyperglycemia, cataleptic attacks, somnolence, Korsakow type of dementia and episodes of acute intracranial hypertension]. Acta Endocrinol Iber 1952 2 : 115 122
21. in Spanish C et al. Cardiovascular risk factors and incident alzheimer disease a systematic review of the literature. Alzheimer Dis Assoc Dis 2009 23 : 1 10.
22. McGuinness B et al. Blood pressure lowering in patients without prior cerebrovascular disease for prevention of cognitive impairment and dementia. Cochrane Database Syst Rev 2009 4 : 39.
23. Kennelly SP et al. Blood pressure and the risk for dementia-a double edged sword. Ageing Res Rev 2009 8 : 61 70.
24. Birns J, Kalra L. Cognitive function and hypertension. J Hum Hypertens 2009 23 : 86 96.
25. Fournier A et al. Prevention of dementia by antihypertensive drugs: how AT1-receptor-blockers and dihydropyridines better prevent dementia in hypertensive patients than thiazides and ACE-inhibitors. Expert Rev Neurother 2009 9 : 1413 1431.
26. Shah K et al. Does use of antihypertensive drugs affect the incidence or progression of dementia? A systematic review. Am J Geriatr Pharmacother 2009 7 : 250 261.
27. Huang CQ et al. Cognitive impairment and hypertension among Chinese nonagenarians and centenarians. Hypertens Res 2009 32 : 554 558.
28. Tsivgoulis G et al. Association of higher diastolic blood pressure levels with cognitive impairment. Neurology 2009 73 : 589 595.
29. Gao SJ et al. Hypertension and cognitive decline in rural elderly Chinese. J Am Geriatr Soc 2009 57 : 1051 1057.
30. Brown JP et al. Blood pressure reactivity and cognitive function in the baltimore longitudinal study of aging. Health Psychol 2009 28 : 641 646.
31. Euser SM et al. The effect of age on the association between blood pressure and cognitive function later in life. J Am Geriatr Soc 2009 57 : 1232 1237.
32. Knecht S et al. How much does hypertension affect cognition? Explained variance in cross-sectional analysis of non-demented community-dwelling individuals in the SEARCH study. J Neurol Sci 2009 283 (1-2, special issue 1 149 152.
33. Cherbuin N et al. Risk factors of transition from normal cognition to mild cognitive disorder: the PATH through life study. Dement Geriatr Cogn Disord 2009 28 : 47 55.
34. Alonso A et al. Risk of dementia hospitalisation associated with cardiovascular risk factors in midlife and older age: the Atherosclerosis Risk in Communities (ARIC) study. J Neurol Neurosurg Psychiatry 2009 80 : 1194 1201.
35. Stewart R et al. Change in blood pressure and incident dementia a 32-year prospective study. Hypertension 2009 54 : 233 240.
36. Razay G et al. Blood pressure, dementia and Alzheimer's disease: the OPTIMA longitudinal study. Dement Geriatr Cogn Disord 2009 28 : 70 74.
37. Haag MDM et al. Duration of antihypertensive drug use and risk of dementia A prospective cohort study. Neurology 2009 72 : 1727 1734.
38. Qiu CX et al. Low diastolic pressure and risk of dementia in very old people: a longitudinal study. Dement Geriatr Cogn Disord 2009 28 : 213 219.
39. Rastas S et al. Vascular risk factors and dementia in the general population aged >85 years Prospective population-based study. Neurobiol Aging 2010 31 : 1 7.
40. van Bruchem-Visser RL et al. High systolic and pulse pressure levels are associated with better cognitive performance in patients with probable Alzheimer's disease: a cross-sectional observational study in a geriatric outpatient population. Dement Geriatr Cogn Disord 2009 28 : 320 324.
41. Duron E et al. Effects of antihypertensive therapy on cognitive decline in Alzheimer's disease. Am J Hypertens 2009 22 : 1020 1024.
42. Hoffman LB et al. Less Alzheimer disease neuropathology in medicated hypertensive than nonhypertensive persons. Neurology 2009 72 : 1720 1726.
43. Sink KM et al. Angiotensin-converting enzyme inhibitors and cognitive decline in older adults with hypertension results from the Cardiovascular Health Study. Arch Intern Med 2009 169 : 1195 1202.
44. Li N-C et al. Use of angiotensin receptor blockers and risk of dementia in a predominantly male population: prospective cohort analysis. BMJ 2010 340 : b5465.
45. Sink KM et al. Angiotensin-converting enzyme inhibitors and cognitive decline in older adults with hypertension results from the Cardiovascular Health Study. Annual Meeting of the American-Geriatrics-Society. 2-6 May 2007; Seattle, WA: American Medical Association 2007 pp. 1195 1202.
46. Smakotina SA et al. Effect of perindopril on cognitive functions in young and middle aged patients with hypertensive disease. Kardiologiya 2008 48 : 28 33.
47. Skoog I. The relationship between blood pressure and dementia: a review. Biomed Pharmacother 1997 51 : 367 375.
48. Kehoe PG, Wilcock GK. Is inhibition of the renin-angiotensin system a new treatment option for Alzheimer's disease? Lancet Neurol 2007 6 : 373 378.
49. Zou K et al. Angiotensin-converting enzyme converts amyloid beta-protein 1-42 (A beta) to A beta(1-40), and its inhibition enhances brain A beta deposition. J Neurosci 2007 27 : 8628 8635.
50. Firbank MJ et al. Brain atrophy and white matter hyperintensity change in older adults and relationship to blood pressure. J Neurol 2007 254 : 713 721.
51. Gard PR. The role of angiotensin II in cognition and behaviour. Eur J Pharmacol 2002 438 : 1 14.
52. Wright JW, Harding JW. The angiotensin AT receptor subtype as a target for the treatment of memory dysfunction associated with Alzheimer's disease. J Renin Angiotensin Aldosterone Syst 2008 9 : 226 237.
53. Gard P, Rusted J. Angiotensin and Alzheimer's disease: therapeutic prospects. Expert Rev Neurother 2004 4 : 87 96.
54. Gard PR. Cognitive-enhancing effects of angiotensin IV. BMC Neurosci 2008 9 : 6.
55. Gibbs CR et al. The management of hypertensive disease in Black patients. QJM-Int J Med 1999 92 : 187 192.
56. Filigheddu F et al. Clinical variables, not RAAS polymorphisms, predict blood pressure response to ACE inhibitors in Sardinians. Pharmacogenomics 2008 9 : 1419 1427.
57. Schelleman H et al. Drug-gene interaction between the insertion/deletion polymorphism of the angiotensin-converting enzyme gene and anti hypertensive therapy. Ann Pharmacother 2006 40 : 212 218.
58. Schelleman H et al. Interactions between five candidate genes and antihypertensive drug therapy on blood pressure. Pharmacogenomics J 2006 6 : 22 26.
59. Fan X et al. Polymorphisms of ACE2 gene are associated with essential hypertension and antihypertensive effects of captopril in women. Clin Pharmacol Ther 2007 82 : 187 196.
60. Bhatnagar V et al. Angiotensin-converting enzyme gene polymorphism predicts the time-course of blood pressure response to angiotensin converting enzyme inhibition in the AASK trial. J Hypertens 2007 25 : 2082 2092.
61. Kurbanova DR et al. Pharmacogenetic aspects of eprosartan therapy and polymorphic markers of renin-angiotensin-aldosterone system genes in Uzbek patients with essential arterial hypertension. Cardiovasc Ther Prev 2009 8 : 41 46.
62. Moraes CF et al. A common polymorphism in the renin angiotensin system is associated with differential outcome of antihypertensive pharmacotherapy prescribed to Brazilian older women. Clin Chim Acta 2008 396 : 70 75.
63. Liu H et al. Renin-angiotensin-aldosterone system gene polymorphisms and antihypertensive response to irbesartan in Chinese hypertensives. Methods Find Exp Clin Pharmacol 2008 30 : 307 312.
64. Peters R, Beckett N. Hypertension, dementia, and antihypertensive treatment: implications for the very elderly. Curr Hypertens Rep 2009 11 : 277 282.