Extracellular Superoxide Dismutase Accelerates Endothelial Recovery and Inhibits In-Stent Restenosis in Stented Atherosclerotic Watanabe Heritable Hyperlipidemic Rabbit Aorta

Journal of the American College of Cardiology

Volumn 50, Issue 23, 2007, Pages 2249-2253

  Bräsen, Jan Hinrich ^a,b   Leppänen, Olli ^a,c   Inkala, Matias ^a   Heikura, Tommi ^a   Levin, Max ^d   Ahrens, Fabian ^e   Rutanen, Juha ^a   Pietsch, Hubertus ^f   Bergqvist, David ^c   Levonen, Anna Liisa ^a   Basu, Samar ^c   Zeller, Thomas ^g   Klöppel, Günter ^b   Laukkanen, Mikko O ^h   Ylä Herttuala, Seppo ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b UNIVERSITY OF KIEL   (Germany)

^c UPPSALA UNIVERSITY   (Sweden)

^d UNIVERSITY OF GOTHENBURG   (Sweden)

^e HUMBOLDT UNIVERSITY   (Germany)

^f BAYER PHARMA AG   (Germany)

^g UNIVERSITY HEART CENTER FREIBURG BAD KROZINGEN   (Germany)

^h UNIVERSITY OF TURKU   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; SUPEROXIDE DISMUTASE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROSIS; CONTROLLED STUDY; GENE TARGETING; GENE THERAPY; HISTOPATHOLOGY; HYPERLIPIDEMIA; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RESTENOSIS;

ADENOVIRIDAE; ANIMALS; AORTIC DISEASES; ATHEROSCLEROSIS; DISEASE MODELS, ANIMAL; ENDOTHELIUM, VASCULAR; FREE RADICAL SCAVENGERS; GENETIC VECTORS; GRAFT OCCLUSION, VASCULAR; OXIDATIVE STRESS; RABBITS; STENTS; SUPEROXIDE DISMUTASE;

EID: 36448988233     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacc.2007.08.038     Document Type: Article

References (16)

1. Joner M., Finn A.V., Farb A., et al. Pathology of drug-eluting stents in humans: delayed healing and late thrombotic risk. J Am Coll Cardiol 48 (2006) 193-202
2. Ylä-Herttuala S., and Alitalo K. Gene transfer as a tool to induce therapeutic vascular growth. Nat Med 9 (2003) 694-701
3. Berg K., Wiseth R., Bjerve K., et al. Oxidative stress and myocardial damage during elective percutaneous coronary interventions and coronary angiography. A comparison of blood-borne isoprostane and troponin release. Free Radic Res 38 (2004) 517-525
4. Tsimikas S., Lau H.K., Han K.R., et al. Percutaneous coronary intervention results in acute increases in oxidized phospholipids and lipoprotein(a): short-term and long-term immunologic responses to oxidized low-density lipoprotein. Circulation 109 (2004) 3164-3170
5. Szöcs K., Lassegue B., Sorescu D., et al. Upregulation of Nox-based NAD(P)H oxidases in restenosis after carotid injury. Arterioscler Thromb Vasc Biol 22 (2002) 21-27
6. Laukkanen M.O., Kivela A., Rissanen T., et al. Adenovirus-mediated extracellular superoxide dismutase gene therapy reduces neointima formation in balloon-denuded rabbit aorta. Circulation 106 (2002) 1999-2003
7. Leite P.F., Danilovic A., Moriel P., et al. Sustained decrease in superoxide dismutase activity underlies constrictive remodeling after balloon injury in rabbits. Arterioscler Thromb Vasc Biol 23 (2003) 2197-2202
8. Bräsen J.H., Kivela A., Roser K., et al. Angiogenesis, vascular endothelial growth factor and platelet-derived growth factor-BB expression, iron deposition, and oxidation-specific epitopes in stented human coronary arteries. Arterioscler Thromb Vasc Biol 21 (2001) 1720-1726
9. Fattman C.L., Schaefer L.M., and Oury T.D. Extracellular superoxide dismutase in biology and medicine. Free Radic Biol Med 35 (2003) 236-256
10. Agrawal R.S., Muangman S., Layne M.D., et al. Pre-emptive gene therapy using recombinant adeno-associated virus delivery of extracellular superoxide dismutase protects heart against ischemic reperfusion injury, improves ventricular function and prolongs survival. Gene Ther 11 (2004) 962-969
11. Rosenfeld M.E., Tsukada T., Chait A., et al. Fatty streak expansion and maturation in Watanabe heritable hyperlipemic and comparably hypercholesterolemic fat-fed rabbits. Arteriosclerosis 7 (1987) 24-34
12. Glass C.K., and Witztum J.L. Atherosclerosis: the road ahead. Cell 104 (2001) 503-516
13. Leppänen O., Rutanen J., Hiltunen M.O., et al. Oral imatinib mesylate (STI571/gleevec) improves the efficacy of local intravascular vascular endothelial growth factor-C gene transfer in reducing neointimal growth in hypercholesterolemic rabbits. Circulation 109 (2004) 1140-1146
14. Laitinen M., Makinen K., Manninen H., et al. Adenovirus-mediated gene transfer to lower limb artery of patients with chronic critical leg ischemia. Hum Gene Ther 9 (1998) 1481-1486
15. Basu S. Radioimmunoassay of 8-iso-prostaglandin F2alpha: an index for oxidative injury via free radical catalysed lipid peroxidation. Prostaglandins Leukot Essent Fatty Acids 58 (1998) 319-325
16. Schwartz R.S., Edelman E.R., Carter A., et al. Drug-eluting stents in preclinical studies: recommended evaluation from a consensus group. Circulation 106 (2002) 1867-1873