Iodine deficiency activates antioxidant genes and causes DNA damage in the thyroid gland of rats and mice

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1773, Issue 6, 2007, Pages 990-999

  Maier, J ^a,b   van Steeg, H ^c   van Oostrom, C ^c   Paschke, R ^a   Weiss, R E ^d   Krohn, K ^a,b  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b UNIVERSITY HOSPITAL LEIPZIG   (Germany)

^c Laboratory of Toxicology   (Netherlands)

^d UNIVERSITY OF CHICAGO   (United States)

Author keywords

Comet Assay; DNA Damage; Iodine Deficiency; Mutagenesis

Indexed keywords

ANTIOXIDANT; DNA; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; MESSENGER RNA; PEROXIREDOXIN; SUPEROXIDE DISMUTASE; THYROTROPIN; THYROXINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CATALYSIS; CONTROLLED STUDY; DETOXIFICATION; DIET RESTRICTION; DNA DAMAGE; FEEDING BEHAVIOR; GENE EXPRESSION; IODINE DEFICIENCY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; SPONTANEOUS MUTATION; STEADY STATE; THYROID GLAND; THYROID WEIGHT;

ANIMALS; ANTIOXIDANTS; DNA DAMAGE; DNA REPAIR; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HYDROGEN PEROXIDE; IODINE; MICE; MICE, INBRED BALB C; MICE, TRANSGENIC; MUTAGENESIS; OXIDATION-REDUCTION; OXIDOREDUCTASES; POINT MUTATION; RATS; RATS, WISTAR; THYROID GLAND; THYROID NODULE; URACIL;

MUS; RATTUS;

EID: 34249661768     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2007.03.011     Document Type: Article

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